Renal Dysfunction at Discharge and Long-Term Survival in Acute Type A Aortic Dissection

We aimed to investigate the association between renal dysfunction at discharge and long-term survival in acute type A aortic dissection (ATAAD) patients following surgery. From 2000 to 2021, 784 patients underwent aortic repair for an ATAAD. Patients were stratified based on creatinine (Cr) level at...

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Bibliographic Details
Published in:The Journal of surgical research 2024-04, Vol.296, p.472-480
Main Authors: Norton, Elizabeth L., Longi, Faraz N., Wu, Xiaoting, Monaghan, Katelyn, Kim, Karen M., Fukuhara, Shinichi, Patel, Himanshu J., Deeb, G. Michael, Yang, Bo
Format: Article
Language:English
Subjects:
Aortic dissection
Creatinine
Dialysis
Renal dysfunction
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Summary:We aimed to investigate the association between renal dysfunction at discharge and long-term survival in acute type A aortic dissection (ATAAD) patients following surgery. From 2000 to 2021, 784 patients underwent aortic repair for an ATAAD. Patients were stratified based on creatinine (Cr) level at discharge alive or dead: normal Cr (n = 582) and elevated Cr defined as >1.3 mg/dL for males and >1.0 mg/dL for females or on dialysis at discharge (n = 202). Preoperatively, both groups had similar rates of comorbidities except for the elevated-Cr group which had more diabetes, chronic obstructive pulmonary disease, and chronic and acute renal insufficiency. Both groups had similar open ATAAD repair procedures. Postoperative outcomes in the elevated-Cr group were significantly worse, including six times higher operative mortality (20% versus 3.4%, P 
ISSN:0022-4804
1095-8673
DOI:10.1016/j.jss.2023.12.020