Effect of obesity on venous blood flow in the lower limbs

Summary Background and objectives Although obesity is a recognized risk factor for the development of lower limb venous disease, less attention has been paid to objectively measuring the effect of centripetal obesity on blood flow in the lower limbs. Patients and methods The diameter of lower limb v...

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Bibliographic Details
Published in:Journal der Deutschen Dermatologischen Gesellschaft 2023-06, Vol.21 (6), p.622-629
Main Authors: Langan, Ewan A., Wienandt, Malte, Bayer, Andreas, Ellebrecht, Lena, Kahle, Birgit
Format: Article
Language:English
Subjects:
blood
Blood flow
chronic venous disease
Limbs
Obesity
Risk factors
Veins
Veins & arteries
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Summary:Summary Background and objectives Although obesity is a recognized risk factor for the development of lower limb venous disease, less attention has been paid to objectively measuring the effect of centripetal obesity on blood flow in the lower limbs. Patients and methods The diameter of lower limb veins and venous blood flow were measured in 44 patients (65.6 ± 12.5 years, 25 females, 19 males) with centripetal obesity and chronic venous disease. Results The mean diameter of both common femoral veins (CFV) increased significantly in the semi‐supine position following elevation of the panniculus (right: ∆0.73 ± 1.21 mm; p ≤ 0.001, left: ∆1.16 ± 1.42 mm; p ≤ 0.001). Moreover, there was a significant increase in venous flow volume in the left CFV (∆62.96 ± 117.85 ml/min; p  =  0.001). Similarly, there was an increase in the diameter of left great saphenous vein (∆0.24 ± 0.41 mm; p  =  0.002), measured at the mid‐thigh, when the patient lifted their abdominal panniculus. Finally, the grade of obesity correlated with the extent of the venous disease. Conclusions These data provide preliminary evidence that centripetal obesity results in both structural and hemodynamic changes in the lower limb veins, even in the absence of classical reflux.
ISSN:1610-0379
1610-0387
DOI:10.1111/ddg.15062