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The Importance of Muscle Capillarization for Optimizing Satellite Cell Plasticity

Satellite cells are essential for skeletal muscle regeneration, repair, and adaptation. The activity of satellite cells is influenced by their interactions with muscle-resident endothelial cells. We postulate that the microvascular network between muscle fibers plays a critical role in satellite cel...

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Published in:Exercise and sport sciences reviews 2021-10, Vol.49 (4), p.284-290
Main Authors: Nederveen, Joshua P, Betz, Milan W, Snijders, Tim, Parise, Gianni
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Language:English
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description Satellite cells are essential for skeletal muscle regeneration, repair, and adaptation. The activity of satellite cells is influenced by their interactions with muscle-resident endothelial cells. We postulate that the microvascular network between muscle fibers plays a critical role in satellite cell function. Exercise-induced angiogenesis can mitigate the decline in satellite cell function with age.
doi_str_mv 10.1249/jes.0000000000000270
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source LWW_医学期刊
subjects Adaptation, Physiological
Cell Plasticity
Endothelial Cells
Muscle Fibers, Skeletal
Muscle, Skeletal
Satellite Cells, Skeletal Muscle
title The Importance of Muscle Capillarization for Optimizing Satellite Cell Plasticity
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