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A nationwide post-marketing survey of knowledge, attitude and practice toward human papillomavirus vaccine in general population: Implications for vaccine roll-out in mainland China
•HPV vaccine awareness and knowledge is limited in general population.•HPV vaccine uptake is still low in China despite high willingness to be vaccinated.•Safety, lack of knowledge and high price are main obstacles to be vaccinated.•Safety concern, lack of knowledge, and high price of HPV vaccines a...
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| Published in: | Vaccine 2021-01, Vol.39 (1), p.35-44 |
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| container_title | Vaccine |
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| creator | Hu, Shangying Xu, Xiaoqian Zhang, Yanyang Liu, Yawen Yang, Chunxia Wang, Yueyun Wang, Yan Yu, Yanqin Hong, Ying Zhang, Xingxing Bian, Rui Cao, Xian Xu, Lili Zhao, Fanghui |
| description | •HPV vaccine awareness and knowledge is limited in general population.•HPV vaccine uptake is still low in China despite high willingness to be vaccinated.•Safety, lack of knowledge and high price are main obstacles to be vaccinated.•Safety concern, lack of knowledge, and high price of HPV vaccines are main obstacles for general population to get vaccinated.
Human papillomavirus (HPV) vaccine has been increasingly discussed in mainland China since its first approval in 2016. To date, nearly all studies assessing HPV vaccine perceptions and attitudes were implemented during pre-licensure period. Therefore, the nationwide post-marketing survey was conducted to update knowledge, attitudes and practice on HPV vaccine among general population in mainland China.
Participants aged 18–45 years living in mainland China were recruited in April 2019 by multi-stage non-randomized sampling. Sociodemographic factors, HPV and HPV vaccine related awareness, knowledge, attitudes, vaccine uptake and potential obstacles were assessed in questionnaires. Bivariate analysis and multivariate regression were used to identify disparity among subgroups with different sociodemographic characteristics.
4,000 women (32.1 ± 7.81y) and 1,000 men (31.8 ± 7.96y) were included in final analysis. Less than one third of participants had heard of HPV (female: 31%; male: 22%) and HPV vaccine (female: 34%; male: 23%). Knowledge score was also unfavorable on HPV (female: 3 out of 13; male: 1.8 out of 13) and HPV vaccine (female: 3 out of 6; male: 2 out of 5). Only 3% females had been vaccinated three years after HPV licensure in China, although willingness to get vaccinated among those unvaccinated were high (mean willingness score ± SD: female: 3.3 ± 0.97; male: 3.0 ± 0.98). Industry of employment and household income were the major factors related to awareness and knowledge of vaccine, whereas HPV and HPV vaccine awareness were key influential factors for willingness. The main obstacles of vaccination were safety concerns, lack of knowledge, and high price of HPV vaccines.
Findings highlight a lack of vaccine awareness, knowledge, and poor uptake in mainland China and underscore the necessity of health education campaigns. The identified priority groups, contents to be delivered and practical obstacles could furthermore provide insight into health education to reduce disparities and accelerate HPV vaccine roll-out in China. |
| doi_str_mv | 10.1016/j.vaccine.2020.11.029 |
| format | article |
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Human papillomavirus (HPV) vaccine has been increasingly discussed in mainland China since its first approval in 2016. To date, nearly all studies assessing HPV vaccine perceptions and attitudes were implemented during pre-licensure period. Therefore, the nationwide post-marketing survey was conducted to update knowledge, attitudes and practice on HPV vaccine among general population in mainland China.
Participants aged 18–45 years living in mainland China were recruited in April 2019 by multi-stage non-randomized sampling. Sociodemographic factors, HPV and HPV vaccine related awareness, knowledge, attitudes, vaccine uptake and potential obstacles were assessed in questionnaires. Bivariate analysis and multivariate regression were used to identify disparity among subgroups with different sociodemographic characteristics.
4,000 women (32.1 ± 7.81y) and 1,000 men (31.8 ± 7.96y) were included in final analysis. Less than one third of participants had heard of HPV (female: 31%; male: 22%) and HPV vaccine (female: 34%; male: 23%). Knowledge score was also unfavorable on HPV (female: 3 out of 13; male: 1.8 out of 13) and HPV vaccine (female: 3 out of 6; male: 2 out of 5). Only 3% females had been vaccinated three years after HPV licensure in China, although willingness to get vaccinated among those unvaccinated were high (mean willingness score ± SD: female: 3.3 ± 0.97; male: 3.0 ± 0.98). Industry of employment and household income were the major factors related to awareness and knowledge of vaccine, whereas HPV and HPV vaccine awareness were key influential factors for willingness. The main obstacles of vaccination were safety concerns, lack of knowledge, and high price of HPV vaccines.
Findings highlight a lack of vaccine awareness, knowledge, and poor uptake in mainland China and underscore the necessity of health education campaigns. The identified priority groups, contents to be delivered and practical obstacles could furthermore provide insight into health education to reduce disparities and accelerate HPV vaccine roll-out in China.</description><identifier>ISSN: 0264-410X</identifier><identifier>EISSN: 1873-2518</identifier><identifier>DOI: 10.1016/j.vaccine.2020.11.029</identifier><identifier>PMID: 33243631</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Adolescent ; Adult ; Attitudes ; Barriers ; Bivariate analysis ; China ; Cross-Sectional Studies ; Education ; Female ; Health Knowledge, Attitudes, Practice ; HPV vaccine ; Human papillomavirus ; Humans ; Immunization ; Knowledge ; Male ; Marketing ; Men ; Middle Aged ; Papillomavirus Infections - prevention & control ; Papillomavirus Vaccines ; Patient Acceptance of Health Care ; Polls & surveys ; Practice ; Regression analysis ; Subgroups ; Survey ; Surveys and Questionnaires ; Uterine Cervical Neoplasms ; Vaccination ; Vaccines ; Willingness ; Womens health ; Young Adult</subject><ispartof>Vaccine, 2021-01, Vol.39 (1), p.35-44</ispartof><rights>2020 The Authors</rights><rights>Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.</rights><rights>2020. The Authors</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-6e2d7cf0a22080ebae91509ffd41e944423170e8d2693b022f10090e036257683</citedby><cites>FETCH-LOGICAL-c440t-6e2d7cf0a22080ebae91509ffd41e944423170e8d2693b022f10090e036257683</cites><orcidid>0000-0001-9294-0005</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33243631$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hu, Shangying</creatorcontrib><creatorcontrib>Xu, Xiaoqian</creatorcontrib><creatorcontrib>Zhang, Yanyang</creatorcontrib><creatorcontrib>Liu, Yawen</creatorcontrib><creatorcontrib>Yang, Chunxia</creatorcontrib><creatorcontrib>Wang, Yueyun</creatorcontrib><creatorcontrib>Wang, Yan</creatorcontrib><creatorcontrib>Yu, Yanqin</creatorcontrib><creatorcontrib>Hong, Ying</creatorcontrib><creatorcontrib>Zhang, Xingxing</creatorcontrib><creatorcontrib>Bian, Rui</creatorcontrib><creatorcontrib>Cao, Xian</creatorcontrib><creatorcontrib>Xu, Lili</creatorcontrib><creatorcontrib>Zhao, Fanghui</creatorcontrib><title>A nationwide post-marketing survey of knowledge, attitude and practice toward human papillomavirus vaccine in general population: Implications for vaccine roll-out in mainland China</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>•HPV vaccine awareness and knowledge is limited in general population.•HPV vaccine uptake is still low in China despite high willingness to be vaccinated.•Safety, lack of knowledge and high price are main obstacles to be vaccinated.•Safety concern, lack of knowledge, and high price of HPV vaccines are main obstacles for general population to get vaccinated.
Human papillomavirus (HPV) vaccine has been increasingly discussed in mainland China since its first approval in 2016. To date, nearly all studies assessing HPV vaccine perceptions and attitudes were implemented during pre-licensure period. Therefore, the nationwide post-marketing survey was conducted to update knowledge, attitudes and practice on HPV vaccine among general population in mainland China.
Participants aged 18–45 years living in mainland China were recruited in April 2019 by multi-stage non-randomized sampling. Sociodemographic factors, HPV and HPV vaccine related awareness, knowledge, attitudes, vaccine uptake and potential obstacles were assessed in questionnaires. Bivariate analysis and multivariate regression were used to identify disparity among subgroups with different sociodemographic characteristics.
4,000 women (32.1 ± 7.81y) and 1,000 men (31.8 ± 7.96y) were included in final analysis. Less than one third of participants had heard of HPV (female: 31%; male: 22%) and HPV vaccine (female: 34%; male: 23%). Knowledge score was also unfavorable on HPV (female: 3 out of 13; male: 1.8 out of 13) and HPV vaccine (female: 3 out of 6; male: 2 out of 5). Only 3% females had been vaccinated three years after HPV licensure in China, although willingness to get vaccinated among those unvaccinated were high (mean willingness score ± SD: female: 3.3 ± 0.97; male: 3.0 ± 0.98). Industry of employment and household income were the major factors related to awareness and knowledge of vaccine, whereas HPV and HPV vaccine awareness were key influential factors for willingness. The main obstacles of vaccination were safety concerns, lack of knowledge, and high price of HPV vaccines.
Findings highlight a lack of vaccine awareness, knowledge, and poor uptake in mainland China and underscore the necessity of health education campaigns. The identified priority groups, contents to be delivered and practical obstacles could furthermore provide insight into health education to reduce disparities and accelerate HPV vaccine roll-out in China.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Attitudes</subject><subject>Barriers</subject><subject>Bivariate analysis</subject><subject>China</subject><subject>Cross-Sectional Studies</subject><subject>Education</subject><subject>Female</subject><subject>Health Knowledge, Attitudes, Practice</subject><subject>HPV vaccine</subject><subject>Human papillomavirus</subject><subject>Humans</subject><subject>Immunization</subject><subject>Knowledge</subject><subject>Male</subject><subject>Marketing</subject><subject>Men</subject><subject>Middle Aged</subject><subject>Papillomavirus Infections - prevention & control</subject><subject>Papillomavirus Vaccines</subject><subject>Patient Acceptance of Health Care</subject><subject>Polls & surveys</subject><subject>Practice</subject><subject>Regression analysis</subject><subject>Subgroups</subject><subject>Survey</subject><subject>Surveys and Questionnaires</subject><subject>Uterine Cervical Neoplasms</subject><subject>Vaccination</subject><subject>Vaccines</subject><subject>Willingness</subject><subject>Womens health</subject><subject>Young 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nationwide post-marketing survey of knowledge, attitude and practice toward human papillomavirus vaccine in general population: Implications for vaccine roll-out in mainland China</title><author>Hu, Shangying ; Xu, Xiaoqian ; Zhang, Yanyang ; Liu, Yawen ; Yang, Chunxia ; Wang, Yueyun ; Wang, Yan ; Yu, Yanqin ; Hong, Ying ; Zhang, Xingxing ; Bian, Rui ; Cao, Xian ; Xu, Lili ; Zhao, Fanghui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-6e2d7cf0a22080ebae91509ffd41e944423170e8d2693b022f10090e036257683</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Attitudes</topic><topic>Barriers</topic><topic>Bivariate analysis</topic><topic>China</topic><topic>Cross-Sectional Studies</topic><topic>Education</topic><topic>Female</topic><topic>Health Knowledge, Attitudes, Practice</topic><topic>HPV vaccine</topic><topic>Human 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Yan</au><au>Yu, Yanqin</au><au>Hong, Ying</au><au>Zhang, Xingxing</au><au>Bian, Rui</au><au>Cao, Xian</au><au>Xu, Lili</au><au>Zhao, Fanghui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A nationwide post-marketing survey of knowledge, attitude and practice toward human papillomavirus vaccine in general population: Implications for vaccine roll-out in mainland China</atitle><jtitle>Vaccine</jtitle><addtitle>Vaccine</addtitle><date>2021-01-03</date><risdate>2021</risdate><volume>39</volume><issue>1</issue><spage>35</spage><epage>44</epage><pages>35-44</pages><issn>0264-410X</issn><eissn>1873-2518</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>•HPV vaccine awareness and knowledge is limited in general population.•HPV vaccine uptake is still low in China despite high willingness to be vaccinated.•Safety, lack of knowledge and high price are main obstacles to be vaccinated.•Safety concern, lack of knowledge, and high price of HPV vaccines are main obstacles for general population to get vaccinated.
Human papillomavirus (HPV) vaccine has been increasingly discussed in mainland China since its first approval in 2016. To date, nearly all studies assessing HPV vaccine perceptions and attitudes were implemented during pre-licensure period. Therefore, the nationwide post-marketing survey was conducted to update knowledge, attitudes and practice on HPV vaccine among general population in mainland China.
Participants aged 18–45 years living in mainland China were recruited in April 2019 by multi-stage non-randomized sampling. Sociodemographic factors, HPV and HPV vaccine related awareness, knowledge, attitudes, vaccine uptake and potential obstacles were assessed in questionnaires. Bivariate analysis and multivariate regression were used to identify disparity among subgroups with different sociodemographic characteristics.
4,000 women (32.1 ± 7.81y) and 1,000 men (31.8 ± 7.96y) were included in final analysis. Less than one third of participants had heard of HPV (female: 31%; male: 22%) and HPV vaccine (female: 34%; male: 23%). Knowledge score was also unfavorable on HPV (female: 3 out of 13; male: 1.8 out of 13) and HPV vaccine (female: 3 out of 6; male: 2 out of 5). Only 3% females had been vaccinated three years after HPV licensure in China, although willingness to get vaccinated among those unvaccinated were high (mean willingness score ± SD: female: 3.3 ± 0.97; male: 3.0 ± 0.98). Industry of employment and household income were the major factors related to awareness and knowledge of vaccine, whereas HPV and HPV vaccine awareness were key influential factors for willingness. The main obstacles of vaccination were safety concerns, lack of knowledge, and high price of HPV vaccines.
Findings highlight a lack of vaccine awareness, knowledge, and poor uptake in mainland China and underscore the necessity of health education campaigns. The identified priority groups, contents to be delivered and practical obstacles could furthermore provide insight into health education to reduce disparities and accelerate HPV vaccine roll-out in China.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>33243631</pmid><doi>10.1016/j.vaccine.2020.11.029</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0001-9294-0005</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0264-410X |
| ispartof | Vaccine, 2021-01, Vol.39 (1), p.35-44 |
| issn | 0264-410X 1873-2518 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2465438430 |
| source | ScienceDirect Freedom Collection |
| subjects | Adolescent Adult Attitudes Barriers Bivariate analysis China Cross-Sectional Studies Education Female Health Knowledge, Attitudes, Practice HPV vaccine Human papillomavirus Humans Immunization Knowledge Male Marketing Men Middle Aged Papillomavirus Infections - prevention & control Papillomavirus Vaccines Patient Acceptance of Health Care Polls & surveys Practice Regression analysis Subgroups Survey Surveys and Questionnaires Uterine Cervical Neoplasms Vaccination Vaccines Willingness Womens health Young Adult |
| title | A nationwide post-marketing survey of knowledge, attitude and practice toward human papillomavirus vaccine in general population: Implications for vaccine roll-out in mainland China |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-21T23%3A22%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20nationwide%20post-marketing%20survey%20of%20knowledge,%20attitude%20and%20practice%20toward%20human%20papillomavirus%20vaccine%20in%20general%20population:%20Implications%20for%20vaccine%20roll-out%20in%20mainland%20China&rft.jtitle=Vaccine&rft.au=Hu,%20Shangying&rft.date=2021-01-03&rft.volume=39&rft.issue=1&rft.spage=35&rft.epage=44&rft.pages=35-44&rft.issn=0264-410X&rft.eissn=1873-2518&rft_id=info:doi/10.1016/j.vaccine.2020.11.029&rft_dat=%3Cproquest_cross%3E2465438430%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c440t-6e2d7cf0a22080ebae91509ffd41e944423170e8d2693b022f10090e036257683%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2467832860&rft_id=info:pmid/33243631&rfr_iscdi=true |