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National Trends of Tobacco, Alcohol, and Drug Use in Patients Admitted With Acute Myocardial Infarction
Acute myocardial infarction (AMI) is a significant health and economic burden in the US. Tobacco, alcohol, and drug use are established risk factors. We sought to evaluate the national trend of use of each substance in patients admitted with AMI. We used the National Inpatient Sample between 2005 an...
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| Published in: | Cardiovascular revascularization medicine 2021-05, Vol.26, p.26-31 |
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| container_title | Cardiovascular revascularization medicine |
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| creator | Kadri, Amer N. Khodor, Sara Ali, Ahmed Nusairat, Leen Mahmood, Asadullah Nahhas, George Dabbous, Samir Spears, James Jafri, Syed Werns, Steven |
| description | Acute myocardial infarction (AMI) is a significant health and economic burden in the US. Tobacco, alcohol, and drug use are established risk factors. We sought to evaluate the national trend of use of each substance in patients admitted with AMI.
We used the National Inpatient Sample between 2005 and 2017. We included adult patients hospitalized with AMI. International Classification of Diseases, Ninth and Tenth Revisions codes were used to define tobacco, alcohol, cocaine, opioid, cannabis and other drug use. Trends of each substance use were assessed using multivariable Poisson regression, and were expressed as annual percent change (APC) with their 95% confidence intervals (CIs).
A total of 10,796,844 hospitalizations with AMI were included. Among all substances used, tobacco was the most common (32.7%), followed by alcohol (3.2%). Between 2005 and 2017, the prevalence ratio of tobacco use increased from 21.5% to 44.5% with an APC +6.2% (95%CI 6.2%–6.2%). Tobacco users had more percutaneous coronary intervention (41%vs25%) and coronary artery bypass surgery (6.9%vs4.9%), p |
| doi_str_mv | 10.1016/j.carrev.2020.10.021 |
| format | article |
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We used the National Inpatient Sample between 2005 and 2017. We included adult patients hospitalized with AMI. International Classification of Diseases, Ninth and Tenth Revisions codes were used to define tobacco, alcohol, cocaine, opioid, cannabis and other drug use. Trends of each substance use were assessed using multivariable Poisson regression, and were expressed as annual percent change (APC) with their 95% confidence intervals (CIs).
A total of 10,796,844 hospitalizations with AMI were included. Among all substances used, tobacco was the most common (32.7%), followed by alcohol (3.2%). Between 2005 and 2017, the prevalence ratio of tobacco use increased from 21.5% to 44.5% with an APC +6.2% (95%CI 6.2%–6.2%). Tobacco users had more percutaneous coronary intervention (41%vs25%) and coronary artery bypass surgery (6.9%vs4.9%), p < 0.001. Further, there were positive trends in alcohol (APC +3.1%; 95%CI 3.0%–3.2%), opioid (APC +9.0%; 95%CI 8.7%–9.2%), cannabis (APC + 7.2; 95% CI 7%–7.4%), and combined all drug use (+7.1%; 95%CI 7%–7.2%). Meanwhile, there was a slight negative trend in cocaine use.
This analysis outlines the national trends of substance use in patients admitted with AMI and reveals an increasing prevalence of tobacco use, alcohol and drug use. More effective cessation measures are necessary to reduce the risk for AMI and its burden on the healthcare system and economy.
•AMI is among the leading causes of morbidity and mortality in the US.•A downward trend in tobacco use has been observed in the US adult population.•Tobacco is the most commonly used substance in patients with AMI.•Alcohol is the second most commonly used substance in patient with AMI.•Tobacco and alcohol use is increasing in patient with AMI.</description><identifier>ISSN: 1553-8389</identifier><identifier>EISSN: 1878-0938</identifier><identifier>DOI: 10.1016/j.carrev.2020.10.021</identifier><identifier>PMID: 33229134</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Acute myocardial infarction ; Adult ; Alcohol ; Drug use ; Hospital Mortality ; Hospitalization ; Humans ; Myocardial Infarction - epidemiology ; Nicotiana ; Pharmaceutical Preparations ; Risk Factors ; Smoking ; Substance-Related Disorders - epidemiology ; Tobacco Use</subject><ispartof>Cardiovascular revascularization medicine, 2021-05, Vol.26, p.26-31</ispartof><rights>2020 Elsevier Inc.</rights><rights>Copyright © 2020 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c362t-2e7581177f6cb4dd1fb9316b884d5c62cd5ddd57a90be851cbca4106a6f859893</citedby><cites>FETCH-LOGICAL-c362t-2e7581177f6cb4dd1fb9316b884d5c62cd5ddd57a90be851cbca4106a6f859893</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33229134$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kadri, Amer N.</creatorcontrib><creatorcontrib>Khodor, Sara</creatorcontrib><creatorcontrib>Ali, Ahmed</creatorcontrib><creatorcontrib>Nusairat, Leen</creatorcontrib><creatorcontrib>Mahmood, Asadullah</creatorcontrib><creatorcontrib>Nahhas, George</creatorcontrib><creatorcontrib>Dabbous, Samir</creatorcontrib><creatorcontrib>Spears, James</creatorcontrib><creatorcontrib>Jafri, Syed</creatorcontrib><creatorcontrib>Werns, Steven</creatorcontrib><title>National Trends of Tobacco, Alcohol, and Drug Use in Patients Admitted With Acute Myocardial Infarction</title><title>Cardiovascular revascularization medicine</title><addtitle>Cardiovasc Revasc Med</addtitle><description>Acute myocardial infarction (AMI) is a significant health and economic burden in the US. Tobacco, alcohol, and drug use are established risk factors. We sought to evaluate the national trend of use of each substance in patients admitted with AMI.
We used the National Inpatient Sample between 2005 and 2017. We included adult patients hospitalized with AMI. International Classification of Diseases, Ninth and Tenth Revisions codes were used to define tobacco, alcohol, cocaine, opioid, cannabis and other drug use. Trends of each substance use were assessed using multivariable Poisson regression, and were expressed as annual percent change (APC) with their 95% confidence intervals (CIs).
A total of 10,796,844 hospitalizations with AMI were included. Among all substances used, tobacco was the most common (32.7%), followed by alcohol (3.2%). Between 2005 and 2017, the prevalence ratio of tobacco use increased from 21.5% to 44.5% with an APC +6.2% (95%CI 6.2%–6.2%). Tobacco users had more percutaneous coronary intervention (41%vs25%) and coronary artery bypass surgery (6.9%vs4.9%), p < 0.001. Further, there were positive trends in alcohol (APC +3.1%; 95%CI 3.0%–3.2%), opioid (APC +9.0%; 95%CI 8.7%–9.2%), cannabis (APC + 7.2; 95% CI 7%–7.4%), and combined all drug use (+7.1%; 95%CI 7%–7.2%). Meanwhile, there was a slight negative trend in cocaine use.
This analysis outlines the national trends of substance use in patients admitted with AMI and reveals an increasing prevalence of tobacco use, alcohol and drug use. More effective cessation measures are necessary to reduce the risk for AMI and its burden on the healthcare system and economy.
•AMI is among the leading causes of morbidity and mortality in the US.•A downward trend in tobacco use has been observed in the US adult population.•Tobacco is the most commonly used substance in patients with AMI.•Alcohol is the second most commonly used substance in patient with AMI.•Tobacco and alcohol use is increasing in patient with AMI.</description><subject>Acute myocardial infarction</subject><subject>Adult</subject><subject>Alcohol</subject><subject>Drug use</subject><subject>Hospital Mortality</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Myocardial Infarction - epidemiology</subject><subject>Nicotiana</subject><subject>Pharmaceutical Preparations</subject><subject>Risk Factors</subject><subject>Smoking</subject><subject>Substance-Related Disorders - epidemiology</subject><subject>Tobacco Use</subject><issn>1553-8389</issn><issn>1878-0938</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kEtv1TAQhS0EoqXwDxDykkVz8SN2nA3SVcujUnksbsXScsaT1le5cbGdSv33OLqFJasZjc6ZM_MR8pazDWdcf9hvwKWEDxvBxDraMMGfkVNuOtOwXprntVdKNkaa_oS8ynnPmOyE7l6SEymF6LlsT8ntd1dCnN1Edwlnn2kc6S4ODiCe0-0E8S5O59TNnl6m5ZbeZKRhpj-rCeeS6dYfQino6a9Q7ugWloL022Osl_lQd17No0uwBrwmL0Y3ZXzzVM_IzedPu4uvzfWPL1cX2-sGpBalEdgpw3nXjRqG1ns-Dr3kejCm9Qq0AK-896pzPRvQKA4DuJYz7fRoVG96eUbeH_fep_h7wVzsIWTAaXIzxiVb0eqWK6bkKm2PUkgx54SjvU_h4NKj5cyuiO3eHhHbFfE6rYir7d1TwjIc0P8z_WVaBR-PAqx_PgRMNkOlBehDQijWx_D_hD_dIY51</recordid><startdate>202105</startdate><enddate>202105</enddate><creator>Kadri, Amer N.</creator><creator>Khodor, Sara</creator><creator>Ali, Ahmed</creator><creator>Nusairat, Leen</creator><creator>Mahmood, Asadullah</creator><creator>Nahhas, George</creator><creator>Dabbous, Samir</creator><creator>Spears, James</creator><creator>Jafri, Syed</creator><creator>Werns, Steven</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202105</creationdate><title>National Trends of Tobacco, Alcohol, and Drug Use in Patients Admitted With Acute Myocardial Infarction</title><author>Kadri, Amer N. ; Khodor, Sara ; Ali, Ahmed ; Nusairat, Leen ; Mahmood, Asadullah ; Nahhas, George ; Dabbous, Samir ; Spears, James ; Jafri, Syed ; Werns, Steven</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c362t-2e7581177f6cb4dd1fb9316b884d5c62cd5ddd57a90be851cbca4106a6f859893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Acute myocardial infarction</topic><topic>Adult</topic><topic>Alcohol</topic><topic>Drug use</topic><topic>Hospital Mortality</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Myocardial Infarction - epidemiology</topic><topic>Nicotiana</topic><topic>Pharmaceutical Preparations</topic><topic>Risk Factors</topic><topic>Smoking</topic><topic>Substance-Related Disorders - epidemiology</topic><topic>Tobacco Use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kadri, Amer N.</creatorcontrib><creatorcontrib>Khodor, Sara</creatorcontrib><creatorcontrib>Ali, Ahmed</creatorcontrib><creatorcontrib>Nusairat, Leen</creatorcontrib><creatorcontrib>Mahmood, Asadullah</creatorcontrib><creatorcontrib>Nahhas, George</creatorcontrib><creatorcontrib>Dabbous, Samir</creatorcontrib><creatorcontrib>Spears, James</creatorcontrib><creatorcontrib>Jafri, Syed</creatorcontrib><creatorcontrib>Werns, Steven</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cardiovascular revascularization medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kadri, Amer N.</au><au>Khodor, Sara</au><au>Ali, Ahmed</au><au>Nusairat, Leen</au><au>Mahmood, Asadullah</au><au>Nahhas, George</au><au>Dabbous, Samir</au><au>Spears, James</au><au>Jafri, Syed</au><au>Werns, Steven</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>National Trends of Tobacco, Alcohol, and Drug Use in Patients Admitted With Acute Myocardial Infarction</atitle><jtitle>Cardiovascular revascularization medicine</jtitle><addtitle>Cardiovasc Revasc Med</addtitle><date>2021-05</date><risdate>2021</risdate><volume>26</volume><spage>26</spage><epage>31</epage><pages>26-31</pages><issn>1553-8389</issn><eissn>1878-0938</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>Acute myocardial infarction (AMI) is a significant health and economic burden in the US. Tobacco, alcohol, and drug use are established risk factors. We sought to evaluate the national trend of use of each substance in patients admitted with AMI.
We used the National Inpatient Sample between 2005 and 2017. We included adult patients hospitalized with AMI. International Classification of Diseases, Ninth and Tenth Revisions codes were used to define tobacco, alcohol, cocaine, opioid, cannabis and other drug use. Trends of each substance use were assessed using multivariable Poisson regression, and were expressed as annual percent change (APC) with their 95% confidence intervals (CIs).
A total of 10,796,844 hospitalizations with AMI were included. Among all substances used, tobacco was the most common (32.7%), followed by alcohol (3.2%). Between 2005 and 2017, the prevalence ratio of tobacco use increased from 21.5% to 44.5% with an APC +6.2% (95%CI 6.2%–6.2%). Tobacco users had more percutaneous coronary intervention (41%vs25%) and coronary artery bypass surgery (6.9%vs4.9%), p < 0.001. Further, there were positive trends in alcohol (APC +3.1%; 95%CI 3.0%–3.2%), opioid (APC +9.0%; 95%CI 8.7%–9.2%), cannabis (APC + 7.2; 95% CI 7%–7.4%), and combined all drug use (+7.1%; 95%CI 7%–7.2%). Meanwhile, there was a slight negative trend in cocaine use.
This analysis outlines the national trends of substance use in patients admitted with AMI and reveals an increasing prevalence of tobacco use, alcohol and drug use. More effective cessation measures are necessary to reduce the risk for AMI and its burden on the healthcare system and economy.
•AMI is among the leading causes of morbidity and mortality in the US.•A downward trend in tobacco use has been observed in the US adult population.•Tobacco is the most commonly used substance in patients with AMI.•Alcohol is the second most commonly used substance in patient with AMI.•Tobacco and alcohol use is increasing in patient with AMI.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>33229134</pmid><doi>10.1016/j.carrev.2020.10.021</doi><tpages>6</tpages></addata></record> |
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| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | Acute myocardial infarction Adult Alcohol Drug use Hospital Mortality Hospitalization Humans Myocardial Infarction - epidemiology Nicotiana Pharmaceutical Preparations Risk Factors Smoking Substance-Related Disorders - epidemiology Tobacco Use |
| title | National Trends of Tobacco, Alcohol, and Drug Use in Patients Admitted With Acute Myocardial Infarction |
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