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Neuropsychological Functioning in Children with Non-Syndromic Cleft of the Lip and/or Palate

Objective: Evaluate neuropsychological functioning in children with non-syndromic cleft of the lip and/or palate (NSCL/P) through profile variance within type of cleft and comparisons to controls. Methods: Children ages 7 to 17 years participated; 66 had a diagnosis of NSCL/P and 87 were healthy con...

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Published in:Child neuropsychology 2009-09, Vol.15 (5), p.471-484
Main Authors: Conrad, Amy Lynn, Richman, Lynn, Nopoulos, Peg, Dailey, Scott
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Language:English
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creator Conrad, Amy Lynn
Richman, Lynn
Nopoulos, Peg
Dailey, Scott
description Objective: Evaluate neuropsychological functioning in children with non-syndromic cleft of the lip and/or palate (NSCL/P) through profile variance within type of cleft and comparisons to controls. Methods: Children ages 7 to 17 years participated; 66 had a diagnosis of NSCL/P and 87 were healthy controls. Neuropsychological tests of language, visual-perceptual, executive functioning, and memory skills were administered. Between- and within-group differences were assessed. Results: Within cleft types, children with NSCLP had an even profile with equal Verbal and Performance IQ (VIQ and PIQ, respectively). Children with non-syndromic cleft palate only (NSCP) had significantly lower VIQ than PIQ, while children with non-syndromic cleft lip only (NSCL) showed a nonsignificant trend for higher VIQ than PIQ. Overall, subjects with NSCL/P performed lower on measures of expressive language and verbal memory than controls. Conclusions: While deficits in verbal and memory skills for children with NSCL/P remain apparent, there is still uncertainty around the possible influence of cleft type on the pattern of deficits.
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Methods: Children ages 7 to 17 years participated; 66 had a diagnosis of NSCL/P and 87 were healthy controls. Neuropsychological tests of language, visual-perceptual, executive functioning, and memory skills were administered. Between- and within-group differences were assessed. Results: Within cleft types, children with NSCLP had an even profile with equal Verbal and Performance IQ (VIQ and PIQ, respectively). Children with non-syndromic cleft palate only (NSCP) had significantly lower VIQ than PIQ, while children with non-syndromic cleft lip only (NSCL) showed a nonsignificant trend for higher VIQ than PIQ. Overall, subjects with NSCL/P performed lower on measures of expressive language and verbal memory than controls. Conclusions: While deficits in verbal and memory skills for children with NSCL/P remain apparent, there is still uncertainty around the possible influence of cleft type on the pattern of deficits.</description><subject>Adolescent</subject><subject>Child</subject><subject>Children</subject><subject>Cleft</subject><subject>Cleft Lip - psychology</subject><subject>Cleft Palate - psychology</subject><subject>Cognition</subject><subject>Executive Function</subject><subject>Female</subject><subject>Humans</subject><subject>Intelligence</subject><subject>Male</subject><subject>Memory</subject><subject>Neuropsychological Tests</subject><subject>Non-syndromic</subject><subject>Verbal skill</subject><issn>0929-7049</issn><issn>1744-4136</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>7T9</sourceid><recordid>eNqFkUuLFDEUhYMoTjv6A9xIVroqJ4-qSgpEkMZRoRkFdSeEVB5dkVTSJinH_vem6cYHg87qBs53zr3hAPAYo-cYcXSBBjIw1NYn6QeMCboDVpi1bdNi2t8Fq4PeVGA4Aw9y_ooQ7hmm98EZHjBvGeMr8OXKLCnu8l5N0cetU9LDyyWo4mJwYQtdgOvJeZ1MgNeuTPAqhubjPugUZ6fg2htbYLSwTAZu3A7KoC9igh-kl8U8BPes9Nk8Os1z8Pny9af122bz_s279atNo7oel4abQevRKtm2Eiut21EpXhVsO0s47y0mI0E9k3hsST9iRjtJkeattb3klNBz8PKYu1vG2WhlQknSi11ys0x7EaUTfyvBTWIbvwtKcF3Ea8CzU0CK3xaTi5hdVsZ7GUxcsuCcDZSTYajk0_-THatFkNtBcsAo6iqIj6BKMedk7K-7MRKHmsWNmqvnyZ8f_u049VoBdgRcsDHN8jomr0WRex-TTTIol2_GivKjVOeLW53035f9BFNIyPc</recordid><startdate>200909</startdate><enddate>200909</enddate><creator>Conrad, Amy Lynn</creator><creator>Richman, Lynn</creator><creator>Nopoulos, Peg</creator><creator>Dailey, Scott</creator><general>Taylor &amp; Francis Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7T9</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>200909</creationdate><title>Neuropsychological Functioning in Children with Non-Syndromic Cleft of the Lip and/or Palate</title><author>Conrad, Amy Lynn ; Richman, Lynn ; Nopoulos, Peg ; Dailey, Scott</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c561t-8e9ddbfca44a1cdd4bcc85611f5f2886f12b2067a1b426b1735a30d84ff6a8323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adolescent</topic><topic>Child</topic><topic>Children</topic><topic>Cleft</topic><topic>Cleft Lip - psychology</topic><topic>Cleft Palate - psychology</topic><topic>Cognition</topic><topic>Executive Function</topic><topic>Female</topic><topic>Humans</topic><topic>Intelligence</topic><topic>Male</topic><topic>Memory</topic><topic>Neuropsychological Tests</topic><topic>Non-syndromic</topic><topic>Verbal skill</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Conrad, Amy Lynn</creatorcontrib><creatorcontrib>Richman, Lynn</creatorcontrib><creatorcontrib>Nopoulos, Peg</creatorcontrib><creatorcontrib>Dailey, Scott</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Linguistics and Language Behavior Abstracts (LLBA)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Child neuropsychology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Conrad, Amy Lynn</au><au>Richman, Lynn</au><au>Nopoulos, Peg</au><au>Dailey, Scott</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neuropsychological Functioning in Children with Non-Syndromic Cleft of the Lip and/or Palate</atitle><jtitle>Child neuropsychology</jtitle><addtitle>Child Neuropsychol</addtitle><date>2009-09</date><risdate>2009</risdate><volume>15</volume><issue>5</issue><spage>471</spage><epage>484</epage><pages>471-484</pages><issn>0929-7049</issn><eissn>1744-4136</eissn><coden>CHNEFJ</coden><notes>ObjectType-Article-2</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-1</notes><notes>content type line 23</notes><notes>ObjectType-Article-1</notes><notes>ObjectType-Feature-2</notes><abstract>Objective: Evaluate neuropsychological functioning in children with non-syndromic cleft of the lip and/or palate (NSCL/P) through profile variance within type of cleft and comparisons to controls. 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source Taylor & Francis; Linguistics and Language Behavior Abstracts (LLBA)
subjects Adolescent
Child
Children
Cleft
Cleft Lip - psychology
Cleft Palate - psychology
Cognition
Executive Function
Female
Humans
Intelligence
Male
Memory
Neuropsychological Tests
Non-syndromic
Verbal skill
title Neuropsychological Functioning in Children with Non-Syndromic Cleft of the Lip and/or Palate
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