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Retinal Neurostimulator for a Multifocal Vision Prosthesis
A neurostimulator application-specific integrated circuit (ASIC) with scalable circuitry that can stimulate 14 channels, has been developed for an epi-retinal vision prosthesis. This ASIC was designed to allow seven identical units to be connected to control up to 98 channels, with the ability to st...
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| Published in: | IEEE transactions on neural systems and rehabilitation engineering 2007-09, Vol.15 (3), p.425-434 |
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| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c560t-c3e177657eb7a6f1fa3d740aa14810ee153150cf456aa97855b0e6e7f78b3263 |
| container_end_page | 434 |
| container_issue | 3 |
| container_start_page | 425 |
| container_title | IEEE transactions on neural systems and rehabilitation engineering |
| container_volume | 15 |
| creator | Wong, Yan T. Dommel, Norbert Preston, Philip Hallum, Luke E. Lehmann, Torsten Lovell, Nigel H. Suaning, Gregg J. |
| description | A neurostimulator application-specific integrated circuit (ASIC) with scalable circuitry that can stimulate 14 channels, has been developed for an epi-retinal vision prosthesis. This ASIC was designed to allow seven identical units to be connected to control up to 98 channels, with the ability to stimulate 14 electrodes simultaneously. The neurostimulator forms part of a vision prosthesis, designed to restore vision to patients who have lost their sight due to retinal diseases such as retinitis pigmentosa and macular degeneration. For charge balance, the neurostimulator was designed to stimulate with current sources and sinks operating together, and with the ability to drive a hexagonal mosaic of electrodes to reduce the electrical crosstalk that occurs when multiple bipolar stimulation sites are active simultaneously. A hexagonal mosaic of electrodes surrounds each stimulation site and has been shown to effectively isolate each site, increasing the ability to inject localized independent charge into multiple regions simultaneously. |
| doi_str_mv | 10.1109/TNSRE.2007.903958 |
| format | article |
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This ASIC was designed to allow seven identical units to be connected to control up to 98 channels, with the ability to stimulate 14 electrodes simultaneously. The neurostimulator forms part of a vision prosthesis, designed to restore vision to patients who have lost their sight due to retinal diseases such as retinitis pigmentosa and macular degeneration. For charge balance, the neurostimulator was designed to stimulate with current sources and sinks operating together, and with the ability to drive a hexagonal mosaic of electrodes to reduce the electrical crosstalk that occurs when multiple bipolar stimulation sites are active simultaneously. A hexagonal mosaic of electrodes surrounds each stimulation site and has been shown to effectively isolate each site, increasing the ability to inject localized independent charge into multiple regions simultaneously.</description><identifier>ISSN: 1534-4320</identifier><identifier>EISSN: 1558-0210</identifier><identifier>DOI: 10.1109/TNSRE.2007.903958</identifier><identifier>PMID: 17894275</identifier><identifier>CODEN: ITNSB3</identifier><language>eng</language><publisher>United States: IEEE</publisher><subject>Application specific integrated circuits ; Australia ; Biomedical engineering ; Channels ; Charge ; Charge (electric) ; Diseases ; Electric charge ; Electric Stimulation Therapy - instrumentation ; Electric Stimulation Therapy - methods ; Electrical stimulation ; Electrodes ; Electrodes, Implanted ; Equipment Design ; Equipment Failure Analysis ; Eyes & eyesight ; Frequency ; Humans ; Integrated circuit ; Macular degeneration ; neurostimulator ; Pigmentation ; Prostheses ; Prostheses and Implants ; Prosthetics ; Retina ; Retinal Diseases - rehabilitation ; Sensory Aids ; Signal Processing, Computer-Assisted - instrumentation ; simultaneous stimulation ; Stimulation ; Surgical implants ; Therapy, Computer-Assisted - instrumentation ; Therapy, Computer-Assisted - methods ; Vision ; Vision Disorders - rehabilitation ; vision prosthesis</subject><ispartof>IEEE transactions on neural systems and rehabilitation engineering, 2007-09, Vol.15 (3), p.425-434</ispartof><rights>Copyright The Institute of Electrical and Electronics Engineers, Inc. (IEEE) 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c560t-c3e177657eb7a6f1fa3d740aa14810ee153150cf456aa97855b0e6e7f78b3263</citedby><cites>FETCH-LOGICAL-c560t-c3e177657eb7a6f1fa3d740aa14810ee153150cf456aa97855b0e6e7f78b3263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17894275$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wong, Yan T.</creatorcontrib><creatorcontrib>Dommel, Norbert</creatorcontrib><creatorcontrib>Preston, Philip</creatorcontrib><creatorcontrib>Hallum, Luke E.</creatorcontrib><creatorcontrib>Lehmann, Torsten</creatorcontrib><creatorcontrib>Lovell, Nigel H.</creatorcontrib><creatorcontrib>Suaning, Gregg J.</creatorcontrib><title>Retinal Neurostimulator for a Multifocal Vision Prosthesis</title><title>IEEE transactions on neural systems and rehabilitation engineering</title><addtitle>TNSRE</addtitle><addtitle>IEEE Trans Neural Syst Rehabil Eng</addtitle><description>A neurostimulator application-specific integrated circuit (ASIC) with scalable circuitry that can stimulate 14 channels, has been developed for an epi-retinal vision prosthesis. This ASIC was designed to allow seven identical units to be connected to control up to 98 channels, with the ability to stimulate 14 electrodes simultaneously. The neurostimulator forms part of a vision prosthesis, designed to restore vision to patients who have lost their sight due to retinal diseases such as retinitis pigmentosa and macular degeneration. For charge balance, the neurostimulator was designed to stimulate with current sources and sinks operating together, and with the ability to drive a hexagonal mosaic of electrodes to reduce the electrical crosstalk that occurs when multiple bipolar stimulation sites are active simultaneously. A hexagonal mosaic of electrodes surrounds each stimulation site and has been shown to effectively isolate each site, increasing the ability to inject localized independent charge into multiple regions simultaneously.</description><subject>Application specific integrated circuits</subject><subject>Australia</subject><subject>Biomedical engineering</subject><subject>Channels</subject><subject>Charge</subject><subject>Charge (electric)</subject><subject>Diseases</subject><subject>Electric charge</subject><subject>Electric Stimulation Therapy - instrumentation</subject><subject>Electric Stimulation Therapy - methods</subject><subject>Electrical stimulation</subject><subject>Electrodes</subject><subject>Electrodes, Implanted</subject><subject>Equipment Design</subject><subject>Equipment Failure Analysis</subject><subject>Eyes & eyesight</subject><subject>Frequency</subject><subject>Humans</subject><subject>Integrated circuit</subject><subject>Macular degeneration</subject><subject>neurostimulator</subject><subject>Pigmentation</subject><subject>Prostheses</subject><subject>Prostheses and Implants</subject><subject>Prosthetics</subject><subject>Retina</subject><subject>Retinal Diseases - rehabilitation</subject><subject>Sensory Aids</subject><subject>Signal Processing, Computer-Assisted - instrumentation</subject><subject>simultaneous stimulation</subject><subject>Stimulation</subject><subject>Surgical implants</subject><subject>Therapy, Computer-Assisted - instrumentation</subject><subject>Therapy, Computer-Assisted - methods</subject><subject>Vision</subject><subject>Vision Disorders - rehabilitation</subject><subject>vision prosthesis</subject><issn>1534-4320</issn><issn>1558-0210</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNqFkctLAzEQxoMoWh9_gAhSPKiXrTOb53qTUh_gCy1eQ7rOYsq2Wze7B_97s7YoeNBDmMD85kvm-xjbRxggQnY2vn9-Gg1SAD3IgGfSrLEeSmkSSBHWuzsXieApbLHtEKYAqJXUm2wLtclEqmWPnT9R4-eu7N9TW1eh8bO2dE1V94t4XP-uLRtfVHkEXnzw1bz_2FFvFHzYZRuFKwPtreoOG1-OxsPr5Pbh6mZ4cZvkUkGT5JxQd-_SRDtVYOH4qxbgHAqDQBQ_iRLyQkjlXKaNlBMgRbrQZsJTxXfYyVJ2UVfvLYXGznzIqSzdnKo2WKMFZiCBR_L4T1IZjqnQ-C-YdnIRjuDpnyCqqGZQgYzo0S90WrV1dDbYDLWI20G3Cy6hPLoYairsovYzV39YBNtFar8itV2kdhlpnDlcCbeTGb3-TKwyjMDBEvBE9N0WHDhGbz8Bg3CisQ</recordid><startdate>20070901</startdate><enddate>20070901</enddate><creator>Wong, Yan T.</creator><creator>Dommel, Norbert</creator><creator>Preston, Philip</creator><creator>Hallum, Luke E.</creator><creator>Lehmann, Torsten</creator><creator>Lovell, Nigel H.</creator><creator>Suaning, Gregg J.</creator><general>IEEE</general><general>The Institute of Electrical and Electronics Engineers, Inc. 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instrumentation</topic><topic>Electric Stimulation Therapy - methods</topic><topic>Electrical stimulation</topic><topic>Electrodes</topic><topic>Electrodes, Implanted</topic><topic>Equipment Design</topic><topic>Equipment Failure Analysis</topic><topic>Eyes & eyesight</topic><topic>Frequency</topic><topic>Humans</topic><topic>Integrated circuit</topic><topic>Macular degeneration</topic><topic>neurostimulator</topic><topic>Pigmentation</topic><topic>Prostheses</topic><topic>Prostheses and Implants</topic><topic>Prosthetics</topic><topic>Retina</topic><topic>Retinal Diseases - rehabilitation</topic><topic>Sensory Aids</topic><topic>Signal Processing, Computer-Assisted - instrumentation</topic><topic>simultaneous stimulation</topic><topic>Stimulation</topic><topic>Surgical implants</topic><topic>Therapy, Computer-Assisted - instrumentation</topic><topic>Therapy, Computer-Assisted - methods</topic><topic>Vision</topic><topic>Vision Disorders - rehabilitation</topic><topic>vision prosthesis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wong, Yan T.</creatorcontrib><creatorcontrib>Dommel, Norbert</creatorcontrib><creatorcontrib>Preston, Philip</creatorcontrib><creatorcontrib>Hallum, Luke E.</creatorcontrib><creatorcontrib>Lehmann, Torsten</creatorcontrib><creatorcontrib>Lovell, Nigel H.</creatorcontrib><creatorcontrib>Suaning, Gregg J.</creatorcontrib><collection>IEEE All-Society Periodicals Package (ASPP) 2005-present</collection><collection>IEEE All-Society Periodicals Package (ASPP) 1998–Present</collection><collection>IEEE Xplore</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>IEEE transactions on neural systems and rehabilitation engineering</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wong, Yan T.</au><au>Dommel, Norbert</au><au>Preston, Philip</au><au>Hallum, Luke E.</au><au>Lehmann, Torsten</au><au>Lovell, Nigel H.</au><au>Suaning, Gregg J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Retinal Neurostimulator for a Multifocal Vision Prosthesis</atitle><jtitle>IEEE transactions on neural systems and rehabilitation engineering</jtitle><stitle>TNSRE</stitle><addtitle>IEEE Trans Neural Syst Rehabil Eng</addtitle><date>2007-09-01</date><risdate>2007</risdate><volume>15</volume><issue>3</issue><spage>425</spage><epage>434</epage><pages>425-434</pages><issn>1534-4320</issn><eissn>1558-0210</eissn><coden>ITNSB3</coden><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>A neurostimulator application-specific integrated circuit (ASIC) with scalable circuitry that can stimulate 14 channels, has been developed for an epi-retinal vision prosthesis. This ASIC was designed to allow seven identical units to be connected to control up to 98 channels, with the ability to stimulate 14 electrodes simultaneously. The neurostimulator forms part of a vision prosthesis, designed to restore vision to patients who have lost their sight due to retinal diseases such as retinitis pigmentosa and macular degeneration. For charge balance, the neurostimulator was designed to stimulate with current sources and sinks operating together, and with the ability to drive a hexagonal mosaic of electrodes to reduce the electrical crosstalk that occurs when multiple bipolar stimulation sites are active simultaneously. A hexagonal mosaic of electrodes surrounds each stimulation site and has been shown to effectively isolate each site, increasing the ability to inject localized independent charge into multiple regions simultaneously.</abstract><cop>United States</cop><pub>IEEE</pub><pmid>17894275</pmid><doi>10.1109/TNSRE.2007.903958</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1534-4320 |
| ispartof | IEEE transactions on neural systems and rehabilitation engineering, 2007-09, Vol.15 (3), p.425-434 |
| issn | 1534-4320 1558-0210 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_20503831 |
| source | Alma/SFX Local Collection |
| subjects | Application specific integrated circuits Australia Biomedical engineering Channels Charge Charge (electric) Diseases Electric charge Electric Stimulation Therapy - instrumentation Electric Stimulation Therapy - methods Electrical stimulation Electrodes Electrodes, Implanted Equipment Design Equipment Failure Analysis Eyes & eyesight Frequency Humans Integrated circuit Macular degeneration neurostimulator Pigmentation Prostheses Prostheses and Implants Prosthetics Retina Retinal Diseases - rehabilitation Sensory Aids Signal Processing, Computer-Assisted - instrumentation simultaneous stimulation Stimulation Surgical implants Therapy, Computer-Assisted - instrumentation Therapy, Computer-Assisted - methods Vision Vision Disorders - rehabilitation vision prosthesis |
| title | Retinal Neurostimulator for a Multifocal Vision Prosthesis |
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