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Evaluation of dose calculation accuracy of various algorithms in lung equivalent inhomogeneity: Comparison of calculated data with Gafchromic film measured results
To evaluate dose calculation accuracy of various algorithms in lung equivalent inhomogeneity comprising tumor within it and comparison with Gafchromic film data. Gafchromic film measured central axis absorbed dose in lung insert (-700 Hounsfield unit [HU]), in racemosa wood cylindrical inhomogeneity...
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| Published in: | Journal of cancer research and therapeutics 2017-10, Vol.13 (6), p.1007-1014 |
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| container_issue | 6 |
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| container_title | Journal of cancer research and therapeutics |
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| creator | Verma, Teerth Raj Painuly, Nirmal K Mishra, Surendra P Singh, Navin Bhatt, M L B Jamal, Naseem Pant, M C |
| description | To evaluate dose calculation accuracy of various algorithms in lung equivalent inhomogeneity comprising tumor within it and comparison with Gafchromic film data.
Gafchromic film measured central axis absorbed dose in lung insert (-700 Hounsfield unit [HU]), in racemosa wood cylindrical inhomogeneity (-725 HU) and at three surfaces of tumor (-20 HU) created in cylindrical inhomogeneity, put in the cavity of computerized imaging reference systems (CIRS) thorax phantom were compared with convolution (CON), superposition (SP), fast SP (FSP), and X-ray voxel Monte Carlo (XVMC) algorithms calculated dose using 6 MV beams of field size 2 cm × 2 cm, 3 cm × 3 cm, 4 cm × 4 cm, 5 cm × 5 cm, and 8 cm × 8 cm.
XVMC was in good agreement with film measured results for all selected field sizes except 3 cm × 3 cm. SP under estimated by 5.7% at the center of the lung insert while deviation up to 6% was found at the cent of wood inhomogeneity in 2 cm × 2 cm. Except CON, increase in dose from proximal to the central surface of the tumor and then dose falloff from central to the distal surface for field size 2 cm × 2 cm to 4 cm × 4 cm was recorded. The change in film measured percentage depth dose from 2 cm × 2 cm to 3 cm × 3 cm field sizes was found -8% however for consecutive field size(s) larger than 3 cm × 3 cm this difference was less. CON and FSP produced overestimated results.
Out of four algorithms, XVMC found consistent with measured data. The electronic disequilibrium within and at the interface of inhomogeneity make the accurate dose predictions difficult. These limitations results in deviations from the expected results of the treatments. |
| doi_str_mv | 10.4103/0973-1482.168992 |
| format | article |
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Gafchromic film measured central axis absorbed dose in lung insert (-700 Hounsfield unit [HU]), in racemosa wood cylindrical inhomogeneity (-725 HU) and at three surfaces of tumor (-20 HU) created in cylindrical inhomogeneity, put in the cavity of computerized imaging reference systems (CIRS) thorax phantom were compared with convolution (CON), superposition (SP), fast SP (FSP), and X-ray voxel Monte Carlo (XVMC) algorithms calculated dose using 6 MV beams of field size 2 cm × 2 cm, 3 cm × 3 cm, 4 cm × 4 cm, 5 cm × 5 cm, and 8 cm × 8 cm.
XVMC was in good agreement with film measured results for all selected field sizes except 3 cm × 3 cm. SP under estimated by 5.7% at the center of the lung insert while deviation up to 6% was found at the cent of wood inhomogeneity in 2 cm × 2 cm. Except CON, increase in dose from proximal to the central surface of the tumor and then dose falloff from central to the distal surface for field size 2 cm × 2 cm to 4 cm × 4 cm was recorded. The change in film measured percentage depth dose from 2 cm × 2 cm to 3 cm × 3 cm field sizes was found -8% however for consecutive field size(s) larger than 3 cm × 3 cm this difference was less. CON and FSP produced overestimated results.
Out of four algorithms, XVMC found consistent with measured data. The electronic disequilibrium within and at the interface of inhomogeneity make the accurate dose predictions difficult. These limitations results in deviations from the expected results of the treatments.</description><identifier>ISSN: 0973-1482</identifier><identifier>EISSN: 1998-4138</identifier><identifier>DOI: 10.4103/0973-1482.168992</identifier><identifier>PMID: 29237967</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Accuracy ; Algorithms ; Calibration ; Cancer therapies ; Care and treatment ; Charged particles ; Computational biology ; Dose-response relationship ; Dosimetry ; Evaluation ; Fourier transforms ; Humans ; Lung - diagnostic imaging ; Lung - pathology ; Lung cancer ; Lung Neoplasms - pathology ; Lung Neoplasms - radiotherapy ; Methods ; Monte Carlo Method ; Phantoms, Imaging ; Planning ; Radiation therapy ; Radiometry - methods ; Radiotherapy ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted - methods ; Specialty products ; Studies ; Thorax</subject><ispartof>Journal of cancer research and therapeutics, 2017-10, Vol.13 (6), p.1007-1014</ispartof><rights>COPYRIGHT 2017 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications & Media Pvt. Ltd. Oct/Dec 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c391t-bfd38df1b47e8dec5e84b8d453a561e0a879f6be11feac6cec34dc0e2523da543</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1978578995?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>315,786,790,25783,27957,27958,37047,37048,44625</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29237967$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Verma, Teerth Raj</creatorcontrib><creatorcontrib>Painuly, Nirmal K</creatorcontrib><creatorcontrib>Mishra, Surendra P</creatorcontrib><creatorcontrib>Singh, Navin</creatorcontrib><creatorcontrib>Bhatt, M L B</creatorcontrib><creatorcontrib>Jamal, Naseem</creatorcontrib><creatorcontrib>Pant, M C</creatorcontrib><title>Evaluation of dose calculation accuracy of various algorithms in lung equivalent inhomogeneity: Comparison of calculated data with Gafchromic film measured results</title><title>Journal of cancer research and therapeutics</title><addtitle>J Cancer Res Ther</addtitle><description>To evaluate dose calculation accuracy of various algorithms in lung equivalent inhomogeneity comprising tumor within it and comparison with Gafchromic film data.
Gafchromic film measured central axis absorbed dose in lung insert (-700 Hounsfield unit [HU]), in racemosa wood cylindrical inhomogeneity (-725 HU) and at three surfaces of tumor (-20 HU) created in cylindrical inhomogeneity, put in the cavity of computerized imaging reference systems (CIRS) thorax phantom were compared with convolution (CON), superposition (SP), fast SP (FSP), and X-ray voxel Monte Carlo (XVMC) algorithms calculated dose using 6 MV beams of field size 2 cm × 2 cm, 3 cm × 3 cm, 4 cm × 4 cm, 5 cm × 5 cm, and 8 cm × 8 cm.
XVMC was in good agreement with film measured results for all selected field sizes except 3 cm × 3 cm. SP under estimated by 5.7% at the center of the lung insert while deviation up to 6% was found at the cent of wood inhomogeneity in 2 cm × 2 cm. Except CON, increase in dose from proximal to the central surface of the tumor and then dose falloff from central to the distal surface for field size 2 cm × 2 cm to 4 cm × 4 cm was recorded. The change in film measured percentage depth dose from 2 cm × 2 cm to 3 cm × 3 cm field sizes was found -8% however for consecutive field size(s) larger than 3 cm × 3 cm this difference was less. CON and FSP produced overestimated results.
Out of four algorithms, XVMC found consistent with measured data. The electronic disequilibrium within and at the interface of inhomogeneity make the accurate dose predictions difficult. These limitations results in deviations from the expected results of the treatments.</description><subject>Accuracy</subject><subject>Algorithms</subject><subject>Calibration</subject><subject>Cancer therapies</subject><subject>Care and treatment</subject><subject>Charged particles</subject><subject>Computational biology</subject><subject>Dose-response relationship</subject><subject>Dosimetry</subject><subject>Evaluation</subject><subject>Fourier transforms</subject><subject>Humans</subject><subject>Lung - diagnostic imaging</subject><subject>Lung - pathology</subject><subject>Lung cancer</subject><subject>Lung Neoplasms - pathology</subject><subject>Lung Neoplasms - radiotherapy</subject><subject>Methods</subject><subject>Monte Carlo Method</subject><subject>Phantoms, Imaging</subject><subject>Planning</subject><subject>Radiation therapy</subject><subject>Radiometry - methods</subject><subject>Radiotherapy</subject><subject>Radiotherapy Dosage</subject><subject>Radiotherapy Planning, Computer-Assisted - methods</subject><subject>Specialty products</subject><subject>Studies</subject><subject>Thorax</subject><issn>0973-1482</issn><issn>1998-4138</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNptkkFvFCEUx4nR2G317smQePEy6wDDDHhrNrWaNPGi5wkDb3ZpGNjC0GY_j19UpttqNBsOJO_9-OXxB4TekXrdkJp9qmXHKtIIuiatkJK-QCsipagawsRLtPrTPkPnKd3WNe8oFa_RGZWUdbLtVujX1b1yWc02eBxGbEICrJXT2R1rSusclT4szXsVbcgJK7cN0c67KWHrsct-i-Eu2yICP5fSLkxhCx7sfPiMN2Hal3Pp6H9Wg8FGzQo_FA2-VqPexTBZjUfrJjyBSjkWJELKbk5v0KtRuQRvn_YL9PPL1Y_N1-rm-_W3zeVNpZkkczWMhgkzkqHpQBjQHEQzCNNwpnhLoFaik2M7ACEjKN1q0KwxugbKKTOKN-wCfTx69zHcZUhzP9mkwTnlody7J7LraC3pI_rhP_Q25OjLdAsleFdeg_-ltiWa3voxzCXLRdpfciI5lQ1bXNUJagkwKhc8lEzgX359gi_LQInw5IH3T8PmYQLT76OdVDz0z7-A_QZnCrbu</recordid><startdate>201710</startdate><enddate>201710</enddate><creator>Verma, Teerth Raj</creator><creator>Painuly, Nirmal K</creator><creator>Mishra, Surendra P</creator><creator>Singh, Navin</creator><creator>Bhatt, M L B</creator><creator>Jamal, Naseem</creator><creator>Pant, M C</creator><general>Medknow Publications and Media Pvt. 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Bhatt, M L B ; Jamal, Naseem ; Pant, M C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-bfd38df1b47e8dec5e84b8d453a561e0a879f6be11feac6cec34dc0e2523da543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Accuracy</topic><topic>Algorithms</topic><topic>Calibration</topic><topic>Cancer therapies</topic><topic>Care and treatment</topic><topic>Charged particles</topic><topic>Computational biology</topic><topic>Dose-response relationship</topic><topic>Dosimetry</topic><topic>Evaluation</topic><topic>Fourier transforms</topic><topic>Humans</topic><topic>Lung - diagnostic imaging</topic><topic>Lung - pathology</topic><topic>Lung cancer</topic><topic>Lung Neoplasms - pathology</topic><topic>Lung Neoplasms - radiotherapy</topic><topic>Methods</topic><topic>Monte Carlo Method</topic><topic>Phantoms, Imaging</topic><topic>Planning</topic><topic>Radiation therapy</topic><topic>Radiometry - methods</topic><topic>Radiotherapy</topic><topic>Radiotherapy Dosage</topic><topic>Radiotherapy Planning, Computer-Assisted - methods</topic><topic>Specialty products</topic><topic>Studies</topic><topic>Thorax</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Verma, Teerth Raj</creatorcontrib><creatorcontrib>Painuly, Nirmal K</creatorcontrib><creatorcontrib>Mishra, Surendra P</creatorcontrib><creatorcontrib>Singh, Navin</creatorcontrib><creatorcontrib>Bhatt, M L B</creatorcontrib><creatorcontrib>Jamal, Naseem</creatorcontrib><creatorcontrib>Pant, M C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cancer research and therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Verma, Teerth Raj</au><au>Painuly, Nirmal K</au><au>Mishra, Surendra P</au><au>Singh, Navin</au><au>Bhatt, M L B</au><au>Jamal, Naseem</au><au>Pant, M C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of dose calculation accuracy of various algorithms in lung equivalent inhomogeneity: Comparison of calculated data with Gafchromic film measured results</atitle><jtitle>Journal of cancer research and therapeutics</jtitle><addtitle>J Cancer Res Ther</addtitle><date>2017-10</date><risdate>2017</risdate><volume>13</volume><issue>6</issue><spage>1007</spage><epage>1014</epage><pages>1007-1014</pages><issn>0973-1482</issn><eissn>1998-4138</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>To evaluate dose calculation accuracy of various algorithms in lung equivalent inhomogeneity comprising tumor within it and comparison with Gafchromic film data.
Gafchromic film measured central axis absorbed dose in lung insert (-700 Hounsfield unit [HU]), in racemosa wood cylindrical inhomogeneity (-725 HU) and at three surfaces of tumor (-20 HU) created in cylindrical inhomogeneity, put in the cavity of computerized imaging reference systems (CIRS) thorax phantom were compared with convolution (CON), superposition (SP), fast SP (FSP), and X-ray voxel Monte Carlo (XVMC) algorithms calculated dose using 6 MV beams of field size 2 cm × 2 cm, 3 cm × 3 cm, 4 cm × 4 cm, 5 cm × 5 cm, and 8 cm × 8 cm.
XVMC was in good agreement with film measured results for all selected field sizes except 3 cm × 3 cm. SP under estimated by 5.7% at the center of the lung insert while deviation up to 6% was found at the cent of wood inhomogeneity in 2 cm × 2 cm. Except CON, increase in dose from proximal to the central surface of the tumor and then dose falloff from central to the distal surface for field size 2 cm × 2 cm to 4 cm × 4 cm was recorded. The change in film measured percentage depth dose from 2 cm × 2 cm to 3 cm × 3 cm field sizes was found -8% however for consecutive field size(s) larger than 3 cm × 3 cm this difference was less. CON and FSP produced overestimated results.
Out of four algorithms, XVMC found consistent with measured data. The electronic disequilibrium within and at the interface of inhomogeneity make the accurate dose predictions difficult. These limitations results in deviations from the expected results of the treatments.</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>29237967</pmid><doi>10.4103/0973-1482.168992</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of cancer research and therapeutics, 2017-10, Vol.13 (6), p.1007-1014 |
| issn | 0973-1482 1998-4138 |
| language | eng |
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| source | Publicly Available Content Database; IngentaConnect Journals |
| subjects | Accuracy Algorithms Calibration Cancer therapies Care and treatment Charged particles Computational biology Dose-response relationship Dosimetry Evaluation Fourier transforms Humans Lung - diagnostic imaging Lung - pathology Lung cancer Lung Neoplasms - pathology Lung Neoplasms - radiotherapy Methods Monte Carlo Method Phantoms, Imaging Planning Radiation therapy Radiometry - methods Radiotherapy Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted - methods Specialty products Studies Thorax |
| title | Evaluation of dose calculation accuracy of various algorithms in lung equivalent inhomogeneity: Comparison of calculated data with Gafchromic film measured results |
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