Loading…

AureoWiki ̵ The repository of the Staphylococcus aureus research and annotation community

In light of continuously accumulating data and knowledge on major human pathogens, comprehensive and up-to-date sources of easily accessible information are urgently required. The AureoWiki database (http://aureowiki.med.uni-greifswald.de) provides detailed information on the genes and proteins of c...

Full description

Saved in:

Bibliographic Details
Published in:	International journal of medical microbiology 2018-08, Vol.308 (6), p.558-568
Main Authors:	Fuchs, Stephan, Mehlan, Henry, Bernhardt, Jörg, Hennig, André, Michalik, Stephan, Surmann, Kristin, Pané-Farré, Jan, Giese, Anne, Weiss, Stefan, Backert, Linus, Herbig, Alexander, Nieselt, Kay, Hecker, Michael, Völker, Uwe, Mäder, Ulrike
Format:	Article
Language:	English
Subjects:	Bacterial Proteins Computational Biology Databases as Topic Gene and protein information Genes, Bacterial Genome, Bacterial Internet Molecular Sequence Annotation Pan-genome S. aureus Staphylococcal Infections - microbiology Staphylococcus aureus - genetics Unified gene names
Citations:	Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

cited_by	cdi_FETCH-LOGICAL-c313t-ee9449e1a7ce2eb5db505866543db185f77461921878596c7f232eee2723a4673
cites
container_end_page	568
container_issue	6
container_start_page	558
container_title	International journal of medical microbiology
container_volume	308
creator	Fuchs, Stephan Mehlan, Henry Bernhardt, Jörg Hennig, André Michalik, Stephan Surmann, Kristin Pané-Farré, Jan Giese, Anne Weiss, Stefan Backert, Linus Herbig, Alexander Nieselt, Kay Hecker, Michael Völker, Uwe Mäder, Ulrike
description	In light of continuously accumulating data and knowledge on major human pathogens, comprehensive and up-to-date sources of easily accessible information are urgently required. The AureoWiki database (http://aureowiki.med.uni-greifswald.de) provides detailed information on the genes and proteins of clinically and experimentally relevant S. aureus strains, currently covering NCTC 8325, COL, Newman, USA300_FPR3757, and N315. By implementing a pan-genome approach, AureoWiki facilitates the transfer of knowledge gained in studies with different S. aureus strains, thus supporting functional annotation and better understanding of this organism. All data related to a given gene or gene product is compiled on a strain-specific gene page. The gene pages contain sequence-based information complemented by data on, for example, protein function and localization, transcriptional regulation, and gene expression. The information provided is connected via links to other databases and published literature. Importantly, orthologous genes of the individual strains, which are linked by a pan-genome gene identifier and a unified gene name, are presented side by side using strain-specific tabs. The respective pan-genome gene page contains an orthologue table for 32 S. aureus strains, a multiple-strain genome viewer, a protein sequence alignment as well as other comparative information. The data collected in AureoWiki is also accessible through various download options in order to support bioinformatics applications. In addition, based on two large-scale gene expression data sets, AureoWiki provides graphical representations of condition-dependent mRNA levels and protein profiles under various laboratory and infection-related conditions.
doi_str_mv	10.1016/j.ijmm.2017.11.011
format	article
fullrecord	<record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1972304251</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1438422117304629</els_id><sourcerecordid>1972304251</sourcerecordid><originalsourceid>FETCH-LOGICAL-c313t-ee9449e1a7ce2eb5db505866543db185f77461921878596c7f232eee2723a4673</originalsourceid><addsrcrecordid>eNo1kM1KxDAQx4Morl8v4EF69NKaSdokBS8ifoHgQUXwErLpLJt126xJKuyD-RY-lFlcD8N_GH4zDD9CToFWQEFcLCq36PuKUZAVQEUBdsgBCFAlFVTu5r7mqqwZgwk5jHFBKWUtF_tkwlpolVL0gLxfjQH9m_twxc938TLHIuDKR5d8WBd-VqQ8eU5mNV8vvfXWjrEweSNHwIgm2Hlhhi7X4JNJzg-F9X0_Di6tj8nezCwjnmzziLze3rxc35ePT3cP11ePpeXAU4nY1nWLYKRFhtOmmza0UUI0Ne-moJqZlLWAloGSqmmFlTPGGSIyybipheRH5Pzv7ir4zxFj0r2LFpdLM6Afo4Y2k7RmDWT0bIuO0x47vQquN2Gt_31k4PIPwPzwl8Ogo3U4WOxcQJt0550Gqjf69UJv9OuNfg2gs37-CzjCeJM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1972304251</pqid></control><display><type>article</type><title>AureoWiki ̵ The repository of the Staphylococcus aureus research and annotation community</title><source>ScienceDirect Journals</source><creator>Fuchs, Stephan ; Mehlan, Henry ; Bernhardt, Jörg ; Hennig, André ; Michalik, Stephan ; Surmann, Kristin ; Pané-Farré, Jan ; Giese, Anne ; Weiss, Stefan ; Backert, Linus ; Herbig, Alexander ; Nieselt, Kay ; Hecker, Michael ; Völker, Uwe ; Mäder, Ulrike</creator><creatorcontrib>Fuchs, Stephan ; Mehlan, Henry ; Bernhardt, Jörg ; Hennig, André ; Michalik, Stephan ; Surmann, Kristin ; Pané-Farré, Jan ; Giese, Anne ; Weiss, Stefan ; Backert, Linus ; Herbig, Alexander ; Nieselt, Kay ; Hecker, Michael ; Völker, Uwe ; Mäder, Ulrike</creatorcontrib><description>In light of continuously accumulating data and knowledge on major human pathogens, comprehensive and up-to-date sources of easily accessible information are urgently required. The AureoWiki database (http://aureowiki.med.uni-greifswald.de) provides detailed information on the genes and proteins of clinically and experimentally relevant S. aureus strains, currently covering NCTC 8325, COL, Newman, USA300_FPR3757, and N315. By implementing a pan-genome approach, AureoWiki facilitates the transfer of knowledge gained in studies with different S. aureus strains, thus supporting functional annotation and better understanding of this organism. All data related to a given gene or gene product is compiled on a strain-specific gene page. The gene pages contain sequence-based information complemented by data on, for example, protein function and localization, transcriptional regulation, and gene expression. The information provided is connected via links to other databases and published literature. Importantly, orthologous genes of the individual strains, which are linked by a pan-genome gene identifier and a unified gene name, are presented side by side using strain-specific tabs. The respective pan-genome gene page contains an orthologue table for 32 S. aureus strains, a multiple-strain genome viewer, a protein sequence alignment as well as other comparative information. The data collected in AureoWiki is also accessible through various download options in order to support bioinformatics applications. In addition, based on two large-scale gene expression data sets, AureoWiki provides graphical representations of condition-dependent mRNA levels and protein profiles under various laboratory and infection-related conditions.</description><identifier>ISSN: 1438-4221</identifier><identifier>EISSN: 1618-0607</identifier><identifier>DOI: 10.1016/j.ijmm.2017.11.011</identifier><identifier>PMID: 29198880</identifier><language>eng</language><publisher>Germany: Elsevier GmbH</publisher><subject>Bacterial Proteins ; Computational Biology ; Databases as Topic ; Gene and protein information ; Genes, Bacterial ; Genome, Bacterial ; Internet ; Molecular Sequence Annotation ; Pan-genome ; S. aureus ; Staphylococcal Infections - microbiology ; Staphylococcus aureus - genetics ; Unified gene names</subject><ispartof>International journal of medical microbiology, 2018-08, Vol.308 (6), p.558-568</ispartof><rights>2017 The Authors</rights><rights>Copyright © 2017 The Authors. Published by Elsevier GmbH.. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c313t-ee9449e1a7ce2eb5db505866543db185f77461921878596c7f232eee2723a4673</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29198880$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fuchs, Stephan</creatorcontrib><creatorcontrib>Mehlan, Henry</creatorcontrib><creatorcontrib>Bernhardt, Jörg</creatorcontrib><creatorcontrib>Hennig, André</creatorcontrib><creatorcontrib>Michalik, Stephan</creatorcontrib><creatorcontrib>Surmann, Kristin</creatorcontrib><creatorcontrib>Pané-Farré, Jan</creatorcontrib><creatorcontrib>Giese, Anne</creatorcontrib><creatorcontrib>Weiss, Stefan</creatorcontrib><creatorcontrib>Backert, Linus</creatorcontrib><creatorcontrib>Herbig, Alexander</creatorcontrib><creatorcontrib>Nieselt, Kay</creatorcontrib><creatorcontrib>Hecker, Michael</creatorcontrib><creatorcontrib>Völker, Uwe</creatorcontrib><creatorcontrib>Mäder, Ulrike</creatorcontrib><title>AureoWiki ̵ The repository of the Staphylococcus aureus research and annotation community</title><title>International journal of medical microbiology</title><addtitle>Int J Med Microbiol</addtitle><description>In light of continuously accumulating data and knowledge on major human pathogens, comprehensive and up-to-date sources of easily accessible information are urgently required. The AureoWiki database (http://aureowiki.med.uni-greifswald.de) provides detailed information on the genes and proteins of clinically and experimentally relevant S. aureus strains, currently covering NCTC 8325, COL, Newman, USA300_FPR3757, and N315. By implementing a pan-genome approach, AureoWiki facilitates the transfer of knowledge gained in studies with different S. aureus strains, thus supporting functional annotation and better understanding of this organism. All data related to a given gene or gene product is compiled on a strain-specific gene page. The gene pages contain sequence-based information complemented by data on, for example, protein function and localization, transcriptional regulation, and gene expression. The information provided is connected via links to other databases and published literature. Importantly, orthologous genes of the individual strains, which are linked by a pan-genome gene identifier and a unified gene name, are presented side by side using strain-specific tabs. The respective pan-genome gene page contains an orthologue table for 32 S. aureus strains, a multiple-strain genome viewer, a protein sequence alignment as well as other comparative information. The data collected in AureoWiki is also accessible through various download options in order to support bioinformatics applications. In addition, based on two large-scale gene expression data sets, AureoWiki provides graphical representations of condition-dependent mRNA levels and protein profiles under various laboratory and infection-related conditions.</description><subject>Bacterial Proteins</subject><subject>Computational Biology</subject><subject>Databases as Topic</subject><subject>Gene and protein information</subject><subject>Genes, Bacterial</subject><subject>Genome, Bacterial</subject><subject>Internet</subject><subject>Molecular Sequence Annotation</subject><subject>Pan-genome</subject><subject>S. aureus</subject><subject>Staphylococcal Infections - microbiology</subject><subject>Staphylococcus aureus - genetics</subject><subject>Unified gene names</subject><issn>1438-4221</issn><issn>1618-0607</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNo1kM1KxDAQx4Morl8v4EF69NKaSdokBS8ifoHgQUXwErLpLJt126xJKuyD-RY-lFlcD8N_GH4zDD9CToFWQEFcLCq36PuKUZAVQEUBdsgBCFAlFVTu5r7mqqwZgwk5jHFBKWUtF_tkwlpolVL0gLxfjQH9m_twxc938TLHIuDKR5d8WBd-VqQ8eU5mNV8vvfXWjrEweSNHwIgm2Hlhhi7X4JNJzg-F9X0_Di6tj8nezCwjnmzziLze3rxc35ePT3cP11ePpeXAU4nY1nWLYKRFhtOmmza0UUI0Ne-moJqZlLWAloGSqmmFlTPGGSIyybipheRH5Pzv7ir4zxFj0r2LFpdLM6Afo4Y2k7RmDWT0bIuO0x47vQquN2Gt_31k4PIPwPzwl8Ogo3U4WOxcQJt0550Gqjf69UJv9OuNfg2gs37-CzjCeJM</recordid><startdate>201808</startdate><enddate>201808</enddate><creator>Fuchs, Stephan</creator><creator>Mehlan, Henry</creator><creator>Bernhardt, Jörg</creator><creator>Hennig, André</creator><creator>Michalik, Stephan</creator><creator>Surmann, Kristin</creator><creator>Pané-Farré, Jan</creator><creator>Giese, Anne</creator><creator>Weiss, Stefan</creator><creator>Backert, Linus</creator><creator>Herbig, Alexander</creator><creator>Nieselt, Kay</creator><creator>Hecker, Michael</creator><creator>Völker, Uwe</creator><creator>Mäder, Ulrike</creator><general>Elsevier GmbH</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201808</creationdate><title>AureoWiki ̵ The repository of the Staphylococcus aureus research and annotation community</title><author>Fuchs, Stephan ; Mehlan, Henry ; Bernhardt, Jörg ; Hennig, André ; Michalik, Stephan ; Surmann, Kristin ; Pané-Farré, Jan ; Giese, Anne ; Weiss, Stefan ; Backert, Linus ; Herbig, Alexander ; Nieselt, Kay ; Hecker, Michael ; Völker, Uwe ; Mäder, Ulrike</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c313t-ee9449e1a7ce2eb5db505866543db185f77461921878596c7f232eee2723a4673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Bacterial Proteins</topic><topic>Computational Biology</topic><topic>Databases as Topic</topic><topic>Gene and protein information</topic><topic>Genes, Bacterial</topic><topic>Genome, Bacterial</topic><topic>Internet</topic><topic>Molecular Sequence Annotation</topic><topic>Pan-genome</topic><topic>S. aureus</topic><topic>Staphylococcal Infections - microbiology</topic><topic>Staphylococcus aureus - genetics</topic><topic>Unified gene names</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fuchs, Stephan</creatorcontrib><creatorcontrib>Mehlan, Henry</creatorcontrib><creatorcontrib>Bernhardt, Jörg</creatorcontrib><creatorcontrib>Hennig, André</creatorcontrib><creatorcontrib>Michalik, Stephan</creatorcontrib><creatorcontrib>Surmann, Kristin</creatorcontrib><creatorcontrib>Pané-Farré, Jan</creatorcontrib><creatorcontrib>Giese, Anne</creatorcontrib><creatorcontrib>Weiss, Stefan</creatorcontrib><creatorcontrib>Backert, Linus</creatorcontrib><creatorcontrib>Herbig, Alexander</creatorcontrib><creatorcontrib>Nieselt, Kay</creatorcontrib><creatorcontrib>Hecker, Michael</creatorcontrib><creatorcontrib>Völker, Uwe</creatorcontrib><creatorcontrib>Mäder, Ulrike</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of medical microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fuchs, Stephan</au><au>Mehlan, Henry</au><au>Bernhardt, Jörg</au><au>Hennig, André</au><au>Michalik, Stephan</au><au>Surmann, Kristin</au><au>Pané-Farré, Jan</au><au>Giese, Anne</au><au>Weiss, Stefan</au><au>Backert, Linus</au><au>Herbig, Alexander</au><au>Nieselt, Kay</au><au>Hecker, Michael</au><au>Völker, Uwe</au><au>Mäder, Ulrike</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>AureoWiki ̵ The repository of the Staphylococcus aureus research and annotation community</atitle><jtitle>International journal of medical microbiology</jtitle><addtitle>Int J Med Microbiol</addtitle><date>2018-08</date><risdate>2018</risdate><volume>308</volume><issue>6</issue><spage>558</spage><epage>568</epage><pages>558-568</pages><issn>1438-4221</issn><eissn>1618-0607</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>In light of continuously accumulating data and knowledge on major human pathogens, comprehensive and up-to-date sources of easily accessible information are urgently required. The AureoWiki database (http://aureowiki.med.uni-greifswald.de) provides detailed information on the genes and proteins of clinically and experimentally relevant S. aureus strains, currently covering NCTC 8325, COL, Newman, USA300_FPR3757, and N315. By implementing a pan-genome approach, AureoWiki facilitates the transfer of knowledge gained in studies with different S. aureus strains, thus supporting functional annotation and better understanding of this organism. All data related to a given gene or gene product is compiled on a strain-specific gene page. The gene pages contain sequence-based information complemented by data on, for example, protein function and localization, transcriptional regulation, and gene expression. The information provided is connected via links to other databases and published literature. Importantly, orthologous genes of the individual strains, which are linked by a pan-genome gene identifier and a unified gene name, are presented side by side using strain-specific tabs. The respective pan-genome gene page contains an orthologue table for 32 S. aureus strains, a multiple-strain genome viewer, a protein sequence alignment as well as other comparative information. The data collected in AureoWiki is also accessible through various download options in order to support bioinformatics applications. In addition, based on two large-scale gene expression data sets, AureoWiki provides graphical representations of condition-dependent mRNA levels and protein profiles under various laboratory and infection-related conditions.</abstract><cop>Germany</cop><pub>Elsevier GmbH</pub><pmid>29198880</pmid><doi>10.1016/j.ijmm.2017.11.011</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record>
fulltext	fulltext
identifier	ISSN: 1438-4221
ispartof	International journal of medical microbiology, 2018-08, Vol.308 (6), p.558-568
issn	1438-4221 1618-0607
language	eng
recordid	cdi_proquest_miscellaneous_1972304251
source	ScienceDirect Journals
subjects	Bacterial Proteins Computational Biology Databases as Topic Gene and protein information Genes, Bacterial Genome, Bacterial Internet Molecular Sequence Annotation Pan-genome S. aureus Staphylococcal Infections - microbiology Staphylococcus aureus - genetics Unified gene names
title	AureoWiki ̵ The repository of the Staphylococcus aureus research and annotation community
url	http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-22T14%3A37%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=AureoWiki%20%CC%B5%20The%20repository%20of%20the%20Staphylococcus%20aureus%20research%20and%20annotation%20community&rft.jtitle=International%20journal%20of%20medical%20microbiology&rft.au=Fuchs,%20Stephan&rft.date=2018-08&rft.volume=308&rft.issue=6&rft.spage=558&rft.epage=568&rft.pages=558-568&rft.issn=1438-4221&rft.eissn=1618-0607&rft_id=info:doi/10.1016/j.ijmm.2017.11.011&rft_dat=%3Cproquest_pubme%3E1972304251%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c313t-ee9449e1a7ce2eb5db505866543db185f77461921878596c7f232eee2723a4673%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1972304251&rft_id=info:pmid/29198880&rfr_iscdi=true