Sources of Variation in the Ampicillin-Resistant Escherichia coli Concentration in the Feces of Organic Broiler Chickens

Currently, there are limited published data for the population dynamics of antimicrobial-resistant commensal bacteria. This study was designed to evaluate both the proportions of the Escherichia coli populations that are resistant to ampicillin at the level of the individual chicken on commercial br...

Full description

Saved in:
Bibliographic Details
Published in:Applied and Environmental Microbiology 2007-01, Vol.73 (1), p.203-210
Main Authors: Pleydell, E.J, Brown, P.E, Woodward, M.J, Davies, R.H, French, N.P
Format: Article
Language:English
Subjects:
Ampicillin - pharmacology
Ampicillin Resistance
Animals
Anti-Bacterial Agents - pharmacology
Biological and medical sciences
Body Weight
Chickens - microbiology
Escherichia coli
Escherichia coli - drug effects
Escherichia coli - isolation & purification
Feces - microbiology
Female
Fundamental and applied biological sciences. Psychology
Linear Models
Male
Microbiology
Public Health Microbiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c492t-ab972c0bbe3ba1a524f7f504698c2bb63f75dfb3895eb695ac7579cc99f5c4603
cites cdi_FETCH-LOGICAL-c492t-ab972c0bbe3ba1a524f7f504698c2bb63f75dfb3895eb695ac7579cc99f5c4603
container_end_page 210
container_issue 1
container_start_page 203
container_title Applied and Environmental Microbiology
container_volume 73
creator Pleydell, E.J
Brown, P.E
Woodward, M.J
Davies, R.H
French, N.P
description Currently, there are limited published data for the population dynamics of antimicrobial-resistant commensal bacteria. This study was designed to evaluate both the proportions of the Escherichia coli populations that are resistant to ampicillin at the level of the individual chicken on commercial broiler farms and the feasibility of obtaining repeated measures of fecal E. coli concentrations. Short-term temporal variation in the concentration of fecal E. coli was investigated, and a preliminary assessment was made of potential factors involved in the shedding of high numbers of ampicillin-resistant E. coli by growing birds in the absence of the use of antimicrobial drugs. Multilevel linear regression modeling revealed that the largest component of random variation in log-transformed fecal E. coli concentrations was seen between sampling occasions for individual birds. The incorporation of fixed effects into the model demonstrated that the older, heavier birds in the study were significantly more likely (P = 0.0003) to shed higher numbers of ampicillin-resistant E. coli. This association between increasing weight and high shedding was not seen for the total fecal E. coli population (P = 0.71). This implies that, in the absence of the administration of antimicrobial drugs, the proportion of fecal E. coli that was resistant to ampicillin increased as the birds grew. This study has shown that it is possible to collect quantitative microbiological data on broiler farms and that such data could make valuable contributions to risk assessments concerning the transfer of resistant bacteria between animal and human populations.
doi_str_mv 10.1128/AEM.01482-06
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_19506866</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>19506866</sourcerecordid><originalsourceid>FETCH-LOGICAL-c492t-ab972c0bbe3ba1a524f7f504698c2bb63f75dfb3895eb695ac7579cc99f5c4603</originalsourceid><addsrcrecordid>eNqFkU1v1DAURSMEotPCjjV4AytSnr_jDdIwmgJSUSVK2VqOa08MiT3YGQr_nkwzonTFygufd3Tfu1X1DMMpxqR5s1x_OgXMGlKDeFAtMKim5pSKh9UCQKmaEAZH1XEp3wCAgWgeV0dYQsOFoovq12XaZesKSh59NTmYMaSIQkRj59By2AYb-j7E-rMroYwmjmhdbOdysF0wyKY-oFWK1sUx3xs9cwfpRd6YGCx6l1PoXUarLtjvLpYn1SNv-uKeHt6T6ups_WX1oT6_eP9xtTyvLVNkrE2rJLHQto62BhtOmJeeAxOqsaRtBfWSX_uWNoq7VihurORSWauU55YJoCfV29m73bWDu56T9nqbw2Dyb51M0Pd_Yuj0Jv3UWCqJGZ0Erw6CnH7sXBn1EIp1fW-iS7uiRUMlY_B_ECs-XV-ICXw9gzanUrLzf9Ng0PtO9dSpvu1Uwx5__u8Gd_ChxAl4eQBMsab32UQbyh3XCMwJ7E-BZq4Lm-4mZKdNGbRxg5ZUY01ud3gxI94kbTZ50lxdEsAUplwcU0r_APJYv4c</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19506866</pqid></control><display><type>article</type><title>Sources of Variation in the Ampicillin-Resistant Escherichia coli Concentration in the Feces of Organic Broiler Chickens</title><source>ASM_美国微生物学会期刊</source><source>PubMed Central (Training)</source><creator>Pleydell, E.J ; Brown, P.E ; Woodward, M.J ; Davies, R.H ; French, N.P</creator><creatorcontrib>Pleydell, E.J ; Brown, P.E ; Woodward, M.J ; Davies, R.H ; French, N.P</creatorcontrib><description>Currently, there are limited published data for the population dynamics of antimicrobial-resistant commensal bacteria. This study was designed to evaluate both the proportions of the Escherichia coli populations that are resistant to ampicillin at the level of the individual chicken on commercial broiler farms and the feasibility of obtaining repeated measures of fecal E. coli concentrations. Short-term temporal variation in the concentration of fecal E. coli was investigated, and a preliminary assessment was made of potential factors involved in the shedding of high numbers of ampicillin-resistant E. coli by growing birds in the absence of the use of antimicrobial drugs. Multilevel linear regression modeling revealed that the largest component of random variation in log-transformed fecal E. coli concentrations was seen between sampling occasions for individual birds. The incorporation of fixed effects into the model demonstrated that the older, heavier birds in the study were significantly more likely (P = 0.0003) to shed higher numbers of ampicillin-resistant E. coli. This association between increasing weight and high shedding was not seen for the total fecal E. coli population (P = 0.71). This implies that, in the absence of the administration of antimicrobial drugs, the proportion of fecal E. coli that was resistant to ampicillin increased as the birds grew. This study has shown that it is possible to collect quantitative microbiological data on broiler farms and that such data could make valuable contributions to risk assessments concerning the transfer of resistant bacteria between animal and human populations.</description><identifier>ISSN: 0099-2240</identifier><identifier>EISSN: 1098-5336</identifier><identifier>DOI: 10.1128/AEM.01482-06</identifier><identifier>PMID: 17085693</identifier><identifier>CODEN: AEMIDF</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Ampicillin - pharmacology ; Ampicillin Resistance ; Animals ; Anti-Bacterial Agents - pharmacology ; Biological and medical sciences ; Body Weight ; Chickens - microbiology ; Escherichia coli ; Escherichia coli - drug effects ; Escherichia coli - isolation &amp; purification ; Feces - microbiology ; Female ; Fundamental and applied biological sciences. Psychology ; Linear Models ; Male ; Microbiology ; Public Health Microbiology</subject><ispartof>Applied and Environmental Microbiology, 2007-01, Vol.73 (1), p.203-210</ispartof><rights>2007 INIST-CNRS</rights><rights>Copyright © 2007, American Society for Microbiology 2007</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c492t-ab972c0bbe3ba1a524f7f504698c2bb63f75dfb3895eb695ac7579cc99f5c4603</citedby><cites>FETCH-LOGICAL-c492t-ab972c0bbe3ba1a524f7f504698c2bb63f75dfb3895eb695ac7579cc99f5c4603</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797143/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797143/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,315,733,786,790,891,3207,3208,27957,27958,53827,53829</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=18615200$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17085693$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pleydell, E.J</creatorcontrib><creatorcontrib>Brown, P.E</creatorcontrib><creatorcontrib>Woodward, M.J</creatorcontrib><creatorcontrib>Davies, R.H</creatorcontrib><creatorcontrib>French, N.P</creatorcontrib><title>Sources of Variation in the Ampicillin-Resistant Escherichia coli Concentration in the Feces of Organic Broiler Chickens</title><title>Applied and Environmental Microbiology</title><addtitle>Appl Environ Microbiol</addtitle><description>Currently, there are limited published data for the population dynamics of antimicrobial-resistant commensal bacteria. This study was designed to evaluate both the proportions of the Escherichia coli populations that are resistant to ampicillin at the level of the individual chicken on commercial broiler farms and the feasibility of obtaining repeated measures of fecal E. coli concentrations. Short-term temporal variation in the concentration of fecal E. coli was investigated, and a preliminary assessment was made of potential factors involved in the shedding of high numbers of ampicillin-resistant E. coli by growing birds in the absence of the use of antimicrobial drugs. Multilevel linear regression modeling revealed that the largest component of random variation in log-transformed fecal E. coli concentrations was seen between sampling occasions for individual birds. The incorporation of fixed effects into the model demonstrated that the older, heavier birds in the study were significantly more likely (P = 0.0003) to shed higher numbers of ampicillin-resistant E. coli. This association between increasing weight and high shedding was not seen for the total fecal E. coli population (P = 0.71). This implies that, in the absence of the administration of antimicrobial drugs, the proportion of fecal E. coli that was resistant to ampicillin increased as the birds grew. This study has shown that it is possible to collect quantitative microbiological data on broiler farms and that such data could make valuable contributions to risk assessments concerning the transfer of resistant bacteria between animal and human populations.</description><subject>Ampicillin - pharmacology</subject><subject>Ampicillin Resistance</subject><subject>Animals</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Body Weight</subject><subject>Chickens - microbiology</subject><subject>Escherichia coli</subject><subject>Escherichia coli - drug effects</subject><subject>Escherichia coli - isolation &amp; purification</subject><subject>Feces - microbiology</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Linear Models</subject><subject>Male</subject><subject>Microbiology</subject><subject>Public Health Microbiology</subject><issn>0099-2240</issn><issn>1098-5336</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNqFkU1v1DAURSMEotPCjjV4AytSnr_jDdIwmgJSUSVK2VqOa08MiT3YGQr_nkwzonTFygufd3Tfu1X1DMMpxqR5s1x_OgXMGlKDeFAtMKim5pSKh9UCQKmaEAZH1XEp3wCAgWgeV0dYQsOFoovq12XaZesKSh59NTmYMaSIQkRj59By2AYb-j7E-rMroYwmjmhdbOdysF0wyKY-oFWK1sUx3xs9cwfpRd6YGCx6l1PoXUarLtjvLpYn1SNv-uKeHt6T6ups_WX1oT6_eP9xtTyvLVNkrE2rJLHQto62BhtOmJeeAxOqsaRtBfWSX_uWNoq7VihurORSWauU55YJoCfV29m73bWDu56T9nqbw2Dyb51M0Pd_Yuj0Jv3UWCqJGZ0Erw6CnH7sXBn1EIp1fW-iS7uiRUMlY_B_ECs-XV-ICXw9gzanUrLzf9Ng0PtO9dSpvu1Uwx5__u8Gd_ChxAl4eQBMsab32UQbyh3XCMwJ7E-BZq4Lm-4mZKdNGbRxg5ZUY01ud3gxI94kbTZ50lxdEsAUplwcU0r_APJYv4c</recordid><startdate>20070101</startdate><enddate>20070101</enddate><creator>Pleydell, E.J</creator><creator>Brown, P.E</creator><creator>Woodward, M.J</creator><creator>Davies, R.H</creator><creator>French, N.P</creator><general>American Society for Microbiology</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20070101</creationdate><title>Sources of Variation in the Ampicillin-Resistant Escherichia coli Concentration in the Feces of Organic Broiler Chickens</title><author>Pleydell, E.J ; Brown, P.E ; Woodward, M.J ; Davies, R.H ; French, N.P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c492t-ab972c0bbe3ba1a524f7f504698c2bb63f75dfb3895eb695ac7579cc99f5c4603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Ampicillin - pharmacology</topic><topic>Ampicillin Resistance</topic><topic>Animals</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Body Weight</topic><topic>Chickens - microbiology</topic><topic>Escherichia coli</topic><topic>Escherichia coli - drug effects</topic><topic>Escherichia coli - isolation &amp; purification</topic><topic>Feces - microbiology</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Linear Models</topic><topic>Male</topic><topic>Microbiology</topic><topic>Public Health Microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pleydell, E.J</creatorcontrib><creatorcontrib>Brown, P.E</creatorcontrib><creatorcontrib>Woodward, M.J</creatorcontrib><creatorcontrib>Davies, R.H</creatorcontrib><creatorcontrib>French, N.P</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Applied and Environmental Microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pleydell, E.J</au><au>Brown, P.E</au><au>Woodward, M.J</au><au>Davies, R.H</au><au>French, N.P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sources of Variation in the Ampicillin-Resistant Escherichia coli Concentration in the Feces of Organic Broiler Chickens</atitle><jtitle>Applied and Environmental Microbiology</jtitle><addtitle>Appl Environ Microbiol</addtitle><date>2007-01-01</date><risdate>2007</risdate><volume>73</volume><issue>1</issue><spage>203</spage><epage>210</epage><pages>203-210</pages><issn>0099-2240</issn><eissn>1098-5336</eissn><coden>AEMIDF</coden><notes>http://aem.asm.org/contents-by-date.0.shtml</notes><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><notes>Corresponding author. Mailing address: Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. Phone: 64 6 350 5270. Fax: 64 6 350 5716. E-mail: e.j.pleydell@massey.ac.nz.</notes><abstract>Currently, there are limited published data for the population dynamics of antimicrobial-resistant commensal bacteria. This study was designed to evaluate both the proportions of the Escherichia coli populations that are resistant to ampicillin at the level of the individual chicken on commercial broiler farms and the feasibility of obtaining repeated measures of fecal E. coli concentrations. Short-term temporal variation in the concentration of fecal E. coli was investigated, and a preliminary assessment was made of potential factors involved in the shedding of high numbers of ampicillin-resistant E. coli by growing birds in the absence of the use of antimicrobial drugs. Multilevel linear regression modeling revealed that the largest component of random variation in log-transformed fecal E. coli concentrations was seen between sampling occasions for individual birds. The incorporation of fixed effects into the model demonstrated that the older, heavier birds in the study were significantly more likely (P = 0.0003) to shed higher numbers of ampicillin-resistant E. coli. This association between increasing weight and high shedding was not seen for the total fecal E. coli population (P = 0.71). This implies that, in the absence of the administration of antimicrobial drugs, the proportion of fecal E. coli that was resistant to ampicillin increased as the birds grew. This study has shown that it is possible to collect quantitative microbiological data on broiler farms and that such data could make valuable contributions to risk assessments concerning the transfer of resistant bacteria between animal and human populations.</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>17085693</pmid><doi>10.1128/AEM.01482-06</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0099-2240
ispartof Applied and Environmental Microbiology, 2007-01, Vol.73 (1), p.203-210
issn 0099-2240
1098-5336
language eng
recordid cdi_proquest_miscellaneous_19506866
source ASM_美国微生物学会期刊; PubMed Central (Training)
subjects Ampicillin - pharmacology
Ampicillin Resistance
Animals
Anti-Bacterial Agents - pharmacology
Biological and medical sciences
Body Weight
Chickens - microbiology
Escherichia coli
Escherichia coli - drug effects
Escherichia coli - isolation & purification
Feces - microbiology
Female
Fundamental and applied biological sciences. Psychology
Linear Models
Male
Microbiology
Public Health Microbiology
title Sources of Variation in the Ampicillin-Resistant Escherichia coli Concentration in the Feces of Organic Broiler Chickens
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-22T06%3A30%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Sources%20of%20Variation%20in%20the%20Ampicillin-Resistant%20Escherichia%20coli%20Concentration%20in%20the%20Feces%20of%20Organic%20Broiler%20Chickens&rft.jtitle=Applied%20and%20Environmental%20Microbiology&rft.au=Pleydell,%20E.J&rft.date=2007-01-01&rft.volume=73&rft.issue=1&rft.spage=203&rft.epage=210&rft.pages=203-210&rft.issn=0099-2240&rft.eissn=1098-5336&rft.coden=AEMIDF&rft_id=info:doi/10.1128/AEM.01482-06&rft_dat=%3Cproquest_pubme%3E19506866%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c492t-ab972c0bbe3ba1a524f7f504698c2bb63f75dfb3895eb695ac7579cc99f5c4603%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=19506866&rft_id=info:pmid/17085693&rfr_iscdi=true