Genetic analysis of 20 autosomal STR loci in the Miao ethnic group from Yunnan Province, Southwest China

Abstract The genetic polymorphisms of 20 autosomal short tandem repeat (STR) loci included in the PowerPlex® 21 kit were evaluated from 748 unrelated healthy individuals of the Miao ethnic minority living in the Yunnan province in southwestern China. All of the loci reached Hardy–Weinberg equilibriu...

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Bibliographic Details
Published in:Forensic science international : genetics 2017-05, Vol.28, p.e28-e29
Main Authors: Zhang, Xiufeng, Hu, Liping, Du, Lei, Nie, Aiting, Rao, Min, Pang, Jing bo, Xiran, Zeng, Nie, Shengjie
Format: Article
Language:English
Subjects:
China
Ethnic Groups - genetics
Gene Frequency
Genetic distribution
Genetics, Population
Humans
Miao ethnic minority
Microsatellite Repeats
Pathology
Polymorphism, Genetic
Short tandem repeat (STR)
Yunnan province
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Summary:Abstract The genetic polymorphisms of 20 autosomal short tandem repeat (STR) loci included in the PowerPlex® 21 kit were evaluated from 748 unrelated healthy individuals of the Miao ethnic minority living in the Yunnan province in southwestern China. All of the loci reached Hardy–Weinberg equilibrium. These loci were examined to determine allele frequencies and forensic statistical parameters. The genetic relationship between the Miao population and other Chinese populations were also estimated. The combined discrimination power and probability of excluding paternity of the 20 STR loci were 0.999 999 999 999 999 999 999 991 26 and 0.999 999 975, respectively. The results suggested that the 20 STR loci were highly polymorphic, which makes them suitable for forensic personal identification and paternity testing.
ISSN:1872-4973
1878-0326
DOI:10.1016/j.fsigen.2017.02.003