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Intracellular Metabolism of β-l-2′,3′-Dideoxyadenosine: Relevance to Its Limited Antiviral Activity
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Published in: | Antimicrobial Agents and Chemotherapy 2000-04, Vol.44 (4), p.853-858 |
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creator | PLACIDI, L CRETTON-SCOTT, E GOSSELIN, G PIERRA, C SCHINAZI, R. F IMBACH, J.-L EL KOUNI, M. H SOMMADOSSI, J.-P |
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doi_str_mv | 10.1128/AAC.44.4.853-858.2000 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.44.4.853-858.2000</identifier><identifier>PMID: 10722481</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>2',3'-Dideoxyadenosine ; Adenosine - analogs & derivatives ; Adenosine - pharmacology ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Antiviral Agents - metabolism ; Antiviral Agents - pharmacology ; Biological and medical sciences ; Cell Line ; Cells, Cultured ; Chromatography, High Pressure Liquid ; Cryopreservation ; Dideoxyadenosine ; Dideoxyadenosine - metabolism ; Dideoxyadenosine - pharmacology ; Hepatitis B virus ; Hepatitis B virus - drug effects ; HepG2 cells ; HIV - drug effects ; Human immunodeficiency virus ; Humans ; Liver - cytology ; Liver - metabolism ; Medical sciences ; methylthioadenosine phosphorylase ; Monocytes - metabolism ; Pharmacology. Drug treatments ; Thionucleosides - pharmacology</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2000-04, Vol.44 (4), p.853-858</ispartof><rights>2000 INIST-CNRS</rights><rights>Copyright © 2000 American Society for Microbiology</rights><rights>Copyright © 2000, American Society for Microbiology 2000</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a533t-5bde8d88118db1d36c5d646d86713f0a923b09b65ac684feb19baf5a6c6a6b203</citedby><cites>FETCH-LOGICAL-a533t-5bde8d88118db1d36c5d646d86713f0a923b09b65ac684feb19baf5a6c6a6b203</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.asm.org/doi/pdf/10.1128/AAC.44.4.853-858.2000$$EPDF$$P50$$Gasm2$$H</linktopdf><linktohtml>$$Uhttps://journals.asm.org/doi/full/10.1128/AAC.44.4.853-858.2000$$EHTML$$P50$$Gasm2$$H</linktohtml><link.rule.ids>230,315,730,783,787,888,3195,3196,27936,27937,52763,52764,52765,53804,53806</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1310106$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10722481$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>PLACIDI, L</creatorcontrib><creatorcontrib>CRETTON-SCOTT, E</creatorcontrib><creatorcontrib>GOSSELIN, G</creatorcontrib><creatorcontrib>PIERRA, C</creatorcontrib><creatorcontrib>SCHINAZI, R. F</creatorcontrib><creatorcontrib>IMBACH, J.-L</creatorcontrib><creatorcontrib>EL KOUNI, M. H</creatorcontrib><creatorcontrib>SOMMADOSSI, J.-P</creatorcontrib><title>Intracellular Metabolism of β-l-2′,3′-Dideoxyadenosine: Relevance to Its Limited Antiviral Activity</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob. Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>2',3'-Dideoxyadenosine</subject><subject>Adenosine - analogs & derivatives</subject><subject>Adenosine - pharmacology</subject><subject>Antibiotics. Antiinfectious agents. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>10722481</pmid><doi>10.1128/AAC.44.4.853-858.2000</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | 2',3'-Dideoxyadenosine Adenosine - analogs & derivatives Adenosine - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Antiviral Agents - metabolism Antiviral Agents - pharmacology Biological and medical sciences Cell Line Cells, Cultured Chromatography, High Pressure Liquid Cryopreservation Dideoxyadenosine Dideoxyadenosine - metabolism Dideoxyadenosine - pharmacology Hepatitis B virus Hepatitis B virus - drug effects HepG2 cells HIV - drug effects Human immunodeficiency virus Humans Liver - cytology Liver - metabolism Medical sciences methylthioadenosine phosphorylase Monocytes - metabolism Pharmacology. Drug treatments Thionucleosides - pharmacology |
title | Intracellular Metabolism of β-l-2′,3′-Dideoxyadenosine: Relevance to Its Limited Antiviral Activity |
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