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In vivo biocompatibility versus degree of conversion of resin-reinforced cements in different time periods

ABSTRACT This study focused on test the null hypothesis that there is no difference between the degree of conversion and biocompatibility of different resin reinforced glass ionomer cements (RRGICs). Forty‐eight male Wistar rats were used, distributed into four groups (n = 12), as follows: Group C (...

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Published in:Microscopy research and technique 2014-05, Vol.77 (5), p.335-340
Main Authors: Lacerda-Santos, Rogério, De Farias, Maria Isabel Serpa Simões, De Carvalho, Fabiola Galbiatti, Pithon, Matheus Melo, Alves, Pollianna Muniz, Tanaka, Orlando Motohiro, Guênes, Gymenna Maria Tenório
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creator Lacerda-Santos, Rogério
De Farias, Maria Isabel Serpa Simões
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Tanaka, Orlando Motohiro
Guênes, Gymenna Maria Tenório
description ABSTRACT This study focused on test the null hypothesis that there is no difference between the degree of conversion and biocompatibility of different resin reinforced glass ionomer cements (RRGICs). Forty‐eight male Wistar rats were used, distributed into four groups (n = 12), as follows: Group C (Control, polyethylene), Group FOB (Fuji Ortho Band), Group UBL (Ultra band Lok), and Group MCG (Multicure Glass), in subcutaneous tissue. The events of edema, necrosis, granulation tissue, multinuclear giant cells, young fibroblasts, and collagen formation were analyzed at 7, 15, and 30 days. The degree of conversion was evaluated by the Fourier method. Biocompatibility and degree of conversion were assessed using the Kruskal–Wallis and Dunn tests, and ANOVA and Tukey's test, respectively (P 
doi_str_mv 10.1002/jemt.22348
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Res. Tech</addtitle><date>2014-05</date><risdate>2014</risdate><volume>77</volume><issue>5</issue><spage>335</spage><epage>340</epage><pages>335-340</pages><issn>1059-910X</issn><eissn>1097-0029</eissn><coden>MRTEEO</coden><notes>National Council for Scientific and Technological Development-CNPq (PIBIC scholarship)</notes><notes>istex:E44AFEBDD7BA11439599130F66A89519DEC2DBB3</notes><notes>ark:/67375/WNG-ZKW1RQ33-J</notes><notes>ArticleID:JEMT22348</notes><notes>REVIEW EDITOR: Dr. Chuanbin Mao</notes><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><notes>ObjectType-Article-2</notes><notes>ObjectType-Feature-1</notes><abstract>ABSTRACT This study focused on test the null hypothesis that there is no difference between the degree of conversion and biocompatibility of different resin reinforced glass ionomer cements (RRGICs). Forty‐eight male Wistar rats were used, distributed into four groups (n = 12), as follows: Group C (Control, polyethylene), Group FOB (Fuji Ortho Band), Group UBL (Ultra band Lok), and Group MCG (Multicure Glass), in subcutaneous tissue. The events of edema, necrosis, granulation tissue, multinuclear giant cells, young fibroblasts, and collagen formation were analyzed at 7, 15, and 30 days. The degree of conversion was evaluated by the Fourier method. Biocompatibility and degree of conversion were assessed using the Kruskal–Wallis and Dunn tests, and ANOVA and Tukey's test, respectively (P &lt; 0.05). It was observed that, there was significant difference between Groups FOB and UBL for the presence of young fibroblasts at 15 days (P = 0.034) and between the Control and MCG Groups for the presence of multinucleated giant cells at 30 days (P = 0.009). Monomer conversion increased progressively until day 30, with significant difference between Group FOB and Groups UBL and MCG (P = 0.013) at 15 days. The null hypothesis was partially accepted, Fuji Ortho Band showed a less monomer conversion and a smaller number of young fibroblasts in the time of 15 days. Microsc. Res. Tech. 77:335–340, 2014. © 2014 Wiley Periodicals, Inc.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>24615757</pmid><doi>10.1002/jemt.22348</doi><tpages>6</tpages></addata></record>
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subjects Acrylic Resins - adverse effects
Acrylic Resins - metabolism
Aluminum Silicates - adverse effects
Aluminum Silicates - metabolism
Analysis of variance
Animals
Biocompatibility
Cements
Conversion
Edema - chemically induced
Fibroblasts
Fibroblasts - metabolism
Giant Cells - metabolism
glass ionomer cements
Glass Ionomer Cements - adverse effects
Glass Ionomer Cements - metabolism
Inflammation - chemically induced
Male
Materials Testing - methods
Monomers
Necrosis - chemically induced
Null hypothesis
orthodontics
Polyethylenes
Rats, Wistar
Resin Cements - adverse effects
Resin Cements - metabolism
Time Factors
title In vivo biocompatibility versus degree of conversion of resin-reinforced cements in different time periods
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