Impact of laparoscopic Nissen’s fundoplication on response of disease specific symptoms and quality of life

The aim of this study is to establish responsiveness of gastroesophageal reflux disease (GERD) symptom score, quality of life SF-36 score in GERD with relation to oesophageal manometry and upper gastrointestinal endoscopy following laparoscopic Nissen’s fundoplication (LNF). Interventional prospecti...

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Bibliographic Details
Published in:Updates in surgery 2013-03, Vol.65 (1), p.35-41
Main Authors: Bhandarwar, Ajay H., Kasat, Gaurav V., Palep, J. H., Shaikh, Taher A., Bakhshi, Girish D., Nichat, P. D.
Format: Article
Language:English
Subjects:
Adult
Female
Fundoplication - methods
Gastroesophageal Reflux - surgery
Humans
Laparoscopy
Male
Medicine
Medicine & Public Health
Middle Aged
Original Article
Prospective Studies
Quality of Life
Surgery
Young Adult
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Summary:The aim of this study is to establish responsiveness of gastroesophageal reflux disease (GERD) symptom score, quality of life SF-36 score in GERD with relation to oesophageal manometry and upper gastrointestinal endoscopy following laparoscopic Nissen’s fundoplication (LNF). Interventional prospective study was done enrolling 77 patients of GERD who respond to proton pump inhibitor (PPI) and have undergone LNF, strict diagnostic criteria were followed with GERD score, upper gastrointestinal endoscopy, oesophageal manometry, and endoscopically negative patients have further undergone 24-h pH study. Follow-up was done at 12 and 24 months by GERD score, SF-36 score, endoscopy, oesophageal manometry. GERD score shows significant difference in pre-operative and post-operative score with P value 
ISSN:2038-131X
2038-3312
DOI:10.1007/s13304-012-0193-9