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Systematic review: the applications of nanotechnology in gastroenterology
Summary Background Over the past 30 years, nanotechnology has evolved dramatically. It has captured the interest of variety of fields from computing and electronics to biology and medicine. Recent discoveries have made invaluable changes to future prospects in nanomedicine; and introduced the concep...
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| Published in: | Alimentary pharmacology & therapeutics 2012-08, Vol.36 (3), p.213-221 |
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| Language: | English |
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| container_end_page | 221 |
| container_issue | 3 |
| container_start_page | 213 |
| container_title | Alimentary pharmacology & therapeutics |
| container_volume | 36 |
| creator | Brakmane, G. Winslet, M. Seifalian, A. M. |
| description | Summary
Background
Over the past 30 years, nanotechnology has evolved dramatically. It has captured the interest of variety of fields from computing and electronics to biology and medicine. Recent discoveries have made invaluable changes to future prospects in nanomedicine; and introduced the concept of theranostics. This term offers a patient specific ‘two in one’ modality that comprises of diagnostic and therapeutic tools. Not only nanotechnology has shown great impact on improvements in drug delivery and imaging techniques, but also there have been several ground‐breaking discoveries in regenerative medicine.
Aim
Gastroenterology invites multidisciplinary approach owing to high complexity of gastrointestinal (GI) system; it includes physicians, surgeons, radiologists, pharmacologists and many more. In this article, we concentrate on current developments in nano‐gastroenterology.
Methods
Literature search was performed using Web of Science and Pubmed search engines with terms – nanotechnology, nanomedicine and gastroenterology. Article search was concentrated on developments since 2005.
Results
We have described original and innovative approaches in gastrointestinal drug delivery, inflammatory disease and cancer‐target treatments. Here, we have reviewed advances in GI imaging using nanoparticles as fluorescent contrast, and their potential for site‐specific targeting. This review has also depicted various approaches and novel discoveries in GI regenerative medicine using nanomaterials for scaffold designs and induced pluripotent stem cells as cell source.
Conclusions
Developments in nanotechnology have opened new range of possibilities to help our patients. This includes novel drug delivery vehicles, diagnostic tools for early and targeted disease detection and nanocomposite materials for tissue constructs to overcome cosmetic or physical disabilities. |
| doi_str_mv | 10.1111/j.1365-2036.2012.05179.x |
| format | article |
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Background
Over the past 30 years, nanotechnology has evolved dramatically. It has captured the interest of variety of fields from computing and electronics to biology and medicine. Recent discoveries have made invaluable changes to future prospects in nanomedicine; and introduced the concept of theranostics. This term offers a patient specific ‘two in one’ modality that comprises of diagnostic and therapeutic tools. Not only nanotechnology has shown great impact on improvements in drug delivery and imaging techniques, but also there have been several ground‐breaking discoveries in regenerative medicine.
Aim
Gastroenterology invites multidisciplinary approach owing to high complexity of gastrointestinal (GI) system; it includes physicians, surgeons, radiologists, pharmacologists and many more. In this article, we concentrate on current developments in nano‐gastroenterology.
Methods
Literature search was performed using Web of Science and Pubmed search engines with terms – nanotechnology, nanomedicine and gastroenterology. Article search was concentrated on developments since 2005.
Results
We have described original and innovative approaches in gastrointestinal drug delivery, inflammatory disease and cancer‐target treatments. Here, we have reviewed advances in GI imaging using nanoparticles as fluorescent contrast, and their potential for site‐specific targeting. This review has also depicted various approaches and novel discoveries in GI regenerative medicine using nanomaterials for scaffold designs and induced pluripotent stem cells as cell source.
Conclusions
Developments in nanotechnology have opened new range of possibilities to help our patients. This includes novel drug delivery vehicles, diagnostic tools for early and targeted disease detection and nanocomposite materials for tissue constructs to overcome cosmetic or physical disabilities.</description><identifier>ISSN: 0269-2813</identifier><identifier>EISSN: 1365-2036</identifier><identifier>DOI: 10.1111/j.1365-2036.2012.05179.x</identifier><identifier>PMID: 22686286</identifier><language>eng</language><publisher>Oxford: Blackwell Publishing Ltd</publisher><subject>Biological and medical sciences ; Diagnostic Imaging - methods ; Digestive system ; Drug Delivery Systems - methods ; Gastroenterology - methods ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Medical sciences ; Nanoparticles - administration & dosage ; Nanotechnology - methods ; Pharmacology. Drug treatments ; Regenerative Medicine - methods</subject><ispartof>Alimentary pharmacology & therapeutics, 2012-08, Vol.36 (3), p.213-221</ispartof><rights>2012 Blackwell Publishing Ltd</rights><rights>2015 INIST-CNRS</rights><rights>2012 Blackwell Publishing Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4879-6202d5f24f5d6575a6c1f03e4da2f18eebe2e48014e4226d46380cd7929820563</citedby><cites>FETCH-LOGICAL-c4879-6202d5f24f5d6575a6c1f03e4da2f18eebe2e48014e4226d46380cd7929820563</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2036.2012.05179.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2036.2012.05179.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,786,790,27957,27958,50923,51032</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26067048$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22686286$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Brakmane, G.</creatorcontrib><creatorcontrib>Winslet, M.</creatorcontrib><creatorcontrib>Seifalian, A. M.</creatorcontrib><title>Systematic review: the applications of nanotechnology in gastroenterology</title><title>Alimentary pharmacology & therapeutics</title><addtitle>Aliment Pharmacol Ther</addtitle><description>Summary
Background
Over the past 30 years, nanotechnology has evolved dramatically. It has captured the interest of variety of fields from computing and electronics to biology and medicine. Recent discoveries have made invaluable changes to future prospects in nanomedicine; and introduced the concept of theranostics. This term offers a patient specific ‘two in one’ modality that comprises of diagnostic and therapeutic tools. Not only nanotechnology has shown great impact on improvements in drug delivery and imaging techniques, but also there have been several ground‐breaking discoveries in regenerative medicine.
Aim
Gastroenterology invites multidisciplinary approach owing to high complexity of gastrointestinal (GI) system; it includes physicians, surgeons, radiologists, pharmacologists and many more. In this article, we concentrate on current developments in nano‐gastroenterology.
Methods
Literature search was performed using Web of Science and Pubmed search engines with terms – nanotechnology, nanomedicine and gastroenterology. Article search was concentrated on developments since 2005.
Results
We have described original and innovative approaches in gastrointestinal drug delivery, inflammatory disease and cancer‐target treatments. Here, we have reviewed advances in GI imaging using nanoparticles as fluorescent contrast, and their potential for site‐specific targeting. This review has also depicted various approaches and novel discoveries in GI regenerative medicine using nanomaterials for scaffold designs and induced pluripotent stem cells as cell source.
Conclusions
Developments in nanotechnology have opened new range of possibilities to help our patients. This includes novel drug delivery vehicles, diagnostic tools for early and targeted disease detection and nanocomposite materials for tissue constructs to overcome cosmetic or physical disabilities.</description><subject>Biological and medical sciences</subject><subject>Diagnostic Imaging - methods</subject><subject>Digestive system</subject><subject>Drug Delivery Systems - methods</subject><subject>Gastroenterology - methods</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Nanoparticles - administration & dosage</subject><subject>Nanotechnology - methods</subject><subject>Pharmacology. Drug treatments</subject><subject>Regenerative Medicine - methods</subject><issn>0269-2813</issn><issn>1365-2036</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqNkUFP2zAUxy20CTq2r4ByQdolmf0cOw7SDgiNwlbBpDHtaBnnBVzSuNjpaL_9HNp11_li6_n3f376mZCM0YKl9WleMC5FDpTLAiiDggpW1cX6gEz2F2_IhIKsc1CMH5F3Mc4ppbKicEiOAKSSoOSEXP_YxAEXZnA2C_jb4ctZNjxiZpbLztlU9n3MfJv1pvcD2sfed_5hk7k-ezBxCB77AcNr7T1525ou4ofdfkx-Xn65u7jKZ7fT64vzWW5LVdW5BAqNaKFsRSNFJYy0rKUcy8ZAyxTiPQKWirISyzRmU0quqG2qGmoFVEh-TD5u-y6Df15hHPTCRYtdZ3r0q6gZBQ51VXOVULVFbfAxBmz1MriFCZsE6VGknuvRlx596VGkfhWp1yl6sntldb_AZh_8ay4BpzvARGu6NpjeuviPk6Prcpzh85Z7cR1u_nsAff79bjylfL7Nu_RP633ehCctK14J_etmqr_BbHr5VVxpzv8AiOWdHw</recordid><startdate>201208</startdate><enddate>201208</enddate><creator>Brakmane, G.</creator><creator>Winslet, M.</creator><creator>Seifalian, A. M.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201208</creationdate><title>Systematic review: the applications of nanotechnology in gastroenterology</title><author>Brakmane, G. ; Winslet, M. ; Seifalian, A. M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4879-6202d5f24f5d6575a6c1f03e4da2f18eebe2e48014e4226d46380cd7929820563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Biological and medical sciences</topic><topic>Diagnostic Imaging - methods</topic><topic>Digestive system</topic><topic>Drug Delivery Systems - methods</topic><topic>Gastroenterology - methods</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Nanoparticles - administration & dosage</topic><topic>Nanotechnology - methods</topic><topic>Pharmacology. Drug treatments</topic><topic>Regenerative Medicine - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Brakmane, G.</creatorcontrib><creatorcontrib>Winslet, M.</creatorcontrib><creatorcontrib>Seifalian, A. M.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Alimentary pharmacology & therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brakmane, G.</au><au>Winslet, M.</au><au>Seifalian, A. M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Systematic review: the applications of nanotechnology in gastroenterology</atitle><jtitle>Alimentary pharmacology & therapeutics</jtitle><addtitle>Aliment Pharmacol Ther</addtitle><date>2012-08</date><risdate>2012</risdate><volume>36</volume><issue>3</issue><spage>213</spage><epage>221</epage><pages>213-221</pages><issn>0269-2813</issn><eissn>1365-2036</eissn><notes>istex:6C0E5A9C6C8E27B2FB71D233944BB8AD8401EC41</notes><notes>ArticleID:APT5179</notes><notes>ark:/67375/WNG-K2LGFJ5H-3</notes><notes>Table S1. Summary of drug delivery approaches in nano-gastroenterology. Table S2. Summary of gastrointestinal imaging using nanoparticles. Table S3. Nanotechnology in GI regenerative medicine.</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-4</notes><notes>ObjectType-Undefined-1</notes><notes>content type line 23</notes><notes>ObjectType-Review-2</notes><notes>ObjectType-Article-3</notes><abstract>Summary
Background
Over the past 30 years, nanotechnology has evolved dramatically. It has captured the interest of variety of fields from computing and electronics to biology and medicine. Recent discoveries have made invaluable changes to future prospects in nanomedicine; and introduced the concept of theranostics. This term offers a patient specific ‘two in one’ modality that comprises of diagnostic and therapeutic tools. Not only nanotechnology has shown great impact on improvements in drug delivery and imaging techniques, but also there have been several ground‐breaking discoveries in regenerative medicine.
Aim
Gastroenterology invites multidisciplinary approach owing to high complexity of gastrointestinal (GI) system; it includes physicians, surgeons, radiologists, pharmacologists and many more. In this article, we concentrate on current developments in nano‐gastroenterology.
Methods
Literature search was performed using Web of Science and Pubmed search engines with terms – nanotechnology, nanomedicine and gastroenterology. Article search was concentrated on developments since 2005.
Results
We have described original and innovative approaches in gastrointestinal drug delivery, inflammatory disease and cancer‐target treatments. Here, we have reviewed advances in GI imaging using nanoparticles as fluorescent contrast, and their potential for site‐specific targeting. This review has also depicted various approaches and novel discoveries in GI regenerative medicine using nanomaterials for scaffold designs and induced pluripotent stem cells as cell source.
Conclusions
Developments in nanotechnology have opened new range of possibilities to help our patients. This includes novel drug delivery vehicles, diagnostic tools for early and targeted disease detection and nanocomposite materials for tissue constructs to overcome cosmetic or physical disabilities.</abstract><cop>Oxford</cop><pub>Blackwell Publishing Ltd</pub><pmid>22686286</pmid><doi>10.1111/j.1365-2036.2012.05179.x</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Alimentary pharmacology & therapeutics, 2012-08, Vol.36 (3), p.213-221 |
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| language | eng |
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| source | Wiley Online Library |
| subjects | Biological and medical sciences Diagnostic Imaging - methods Digestive system Drug Delivery Systems - methods Gastroenterology - methods Gastroenterology. Liver. Pancreas. Abdomen Humans Medical sciences Nanoparticles - administration & dosage Nanotechnology - methods Pharmacology. Drug treatments Regenerative Medicine - methods |
| title | Systematic review: the applications of nanotechnology in gastroenterology |
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