Iatrogenic Calcinosis Cutis Successfully Treated with Topical Sodium Thiosulfate

Calcinosis cutis is a term used to describe a group of disorders in which calcium salt deposits form in the skin and subcutaneous tissue. We report a 6‐year‐old boy with hypoparathyroidism after thyroidectomy who was admitted to the hospital for severe hypocalcemia being treated with calcium glucona...

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Bibliographic Details
Published in:Pediatric dermatology 2017-05, Vol.34 (3), p.356-358
Main Authors: García‐García, Emilio, López‐López, Rocío, Álvarez‐del‐Vayo, Concepción, Bernabeu‐Wittel, José
Format: Article
Language:English
Subjects:
Administration, Topical
Calcinosis
Calcinosis - drug therapy
Calcium
Case reports
Child
Children
Humans
Hypocalcemia
Hypoparathyroidism
Iatrogenesis
Iatrogenic Disease
Intravenous administration
Male
Side effects
Skin
Skin Diseases - drug therapy
Skin Diseases - etiology
Sodium
Sodium thiosulfate
Thiosulfate
Thiosulfates - administration & dosage
Thyroidectomy
Veins
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Summary:Calcinosis cutis is a term used to describe a group of disorders in which calcium salt deposits form in the skin and subcutaneous tissue. We report a 6‐year‐old boy with hypoparathyroidism after thyroidectomy who was admitted to the hospital for severe hypocalcemia being treated with calcium gluconate intravenous infusion through peripheral veins. Within a few days we made a diagnosis of iatrogenic calcinosis cutis and treatment with 10% topical sodium thiosulfate was prescribed; complete resolution of lesions was achieved after 6 months, with no local or systemic adverse effects. Because of the lack of noninvasive alternatives and the good tolerance of the treatment, especially in childhood, we suggest the topical use of this drug as an option for this condition.
ISSN:0736-8046
1525-1470
DOI:10.1111/pde.13116