Radiation therapy for bone metastasis of hepatocellular carcinoma

The efficacy of radiation therapy for bone metastasis of hepatocellular carcinoma was examined retrospectively. The effect of radiation therapy for pain and paresis was evaluated in 38 patients who received planned radiation therapy with the total dose ranging from 26 to 60 Gy. The percentage regres...

Full description

Saved in:
Bibliographic Details
Published in:International journal of clinical oncology 1998-02, Vol.3 (1), p.31-35
Main Authors: Matsuura, Masana, Nakajima, Nobuaki, Ito, Kazuki
Format: Article
Language:English
Subjects:
Liver cancer
Medical prognosis
Metastasis
Radiation therapy
Tomography
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c267t-fbce30d1178cd2a5b4695cf52947305ae7bb9075cc10729fe8993f7ef8355b63
cites cdi_FETCH-LOGICAL-c267t-fbce30d1178cd2a5b4695cf52947305ae7bb9075cc10729fe8993f7ef8355b63
container_end_page 35
container_issue 1
container_start_page 31
container_title International journal of clinical oncology
container_volume 3
creator Matsuura, Masana
Nakajima, Nobuaki
Ito, Kazuki
description The efficacy of radiation therapy for bone metastasis of hepatocellular carcinoma was examined retrospectively. The effect of radiation therapy for pain and paresis was evaluated in 38 patients who received planned radiation therapy with the total dose ranging from 26 to 60 Gy. The percentage regression of 14 metastatic bone lesions was calculated by using computed tomography: percentage regression=[(pre-radiation therapy tumor volume--postradiation therapy tumor volume)/pre-radiation therapy tumor volume]×100. The 1-, 2-, and 5-year survival rates of the 38 patients from the start of the radiation therapy were 30% 18%, and 9.0% respectively. The median survival period was 172 days. Pain relief was obtained in 91% of 44 painful bone metastases. No correlation was observed between the percentage regression and the tumor size. Complete regression of bone metastasis was noted in 6 of 14 patients who could be evaluated with computed tomography. Three of the 6 paiients with complete response have survived for more than 6 years after radiation therapy. Radiation therapy is an effective method for palliation of bone metastasis. Although the prognosis of most patients with bone metastasis from hepatocellular carcinoma is poor, some attain longterm survival after treatment.[PUBLICATION ABSTRACT]
doi_str_mv 10.1007/BF02490099
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1530407082</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3319745341</sourcerecordid><originalsourceid>FETCH-LOGICAL-c267t-fbce30d1178cd2a5b4695cf52947305ae7bb9075cc10729fe8993f7ef8355b63</originalsourceid><addsrcrecordid>eNpFkE1LxDAYhIMouK5e_AUBb0L1zVff5rgurgoLguy9JGnCduk2NWkP---trCAMzBweZmAIuWfwxADw-WUDXGoArS_IgkmBBSLyyzkLyQpdcnVNbnI-ADAsFV-Q1ZdpWjO2safj3icznGiIidrYe3r0o8mz2kxjoHs_mDE633VTZxJ1Jrm2j0dzS66C6bK_-_Ml2W1ed-v3Yvv59rFebQvHSxyLYJ0X0DCGlWu4UVaWWrmguJYoQBmP1mpA5RwD5Dr4SmsR0IdKKGVLsSQP59ohxe_J57E-xCn182LNlAAJCBWfqccz5VLMOflQD6k9mnSqGdS_D9X_D4kfeP5XxQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1530407082</pqid></control><display><type>article</type><title>Radiation therapy for bone metastasis of hepatocellular carcinoma</title><source>Springer Link</source><creator>Matsuura, Masana ; Nakajima, Nobuaki ; Ito, Kazuki</creator><creatorcontrib>Matsuura, Masana ; Nakajima, Nobuaki ; Ito, Kazuki</creatorcontrib><description>The efficacy of radiation therapy for bone metastasis of hepatocellular carcinoma was examined retrospectively. The effect of radiation therapy for pain and paresis was evaluated in 38 patients who received planned radiation therapy with the total dose ranging from 26 to 60 Gy. The percentage regression of 14 metastatic bone lesions was calculated by using computed tomography: percentage regression=[(pre-radiation therapy tumor volume--postradiation therapy tumor volume)/pre-radiation therapy tumor volume]×100. The 1-, 2-, and 5-year survival rates of the 38 patients from the start of the radiation therapy were 30% 18%, and 9.0% respectively. The median survival period was 172 days. Pain relief was obtained in 91% of 44 painful bone metastases. No correlation was observed between the percentage regression and the tumor size. Complete regression of bone metastasis was noted in 6 of 14 patients who could be evaluated with computed tomography. Three of the 6 paiients with complete response have survived for more than 6 years after radiation therapy. Radiation therapy is an effective method for palliation of bone metastasis. Although the prognosis of most patients with bone metastasis from hepatocellular carcinoma is poor, some attain longterm survival after treatment.[PUBLICATION ABSTRACT]</description><identifier>ISSN: 1341-9625</identifier><identifier>EISSN: 1437-7772</identifier><identifier>DOI: 10.1007/BF02490099</identifier><language>eng</language><publisher>Tokyo: Springer Nature B.V</publisher><subject>Liver cancer ; Medical prognosis ; Metastasis ; Radiation therapy ; Tomography</subject><ispartof>International journal of clinical oncology, 1998-02, Vol.3 (1), p.31-35</ispartof><rights>The Japan Society of Clinical Oncology/Churchill Livingstone Japan 1998</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c267t-fbce30d1178cd2a5b4695cf52947305ae7bb9075cc10729fe8993f7ef8355b63</citedby><cites>FETCH-LOGICAL-c267t-fbce30d1178cd2a5b4695cf52947305ae7bb9075cc10729fe8993f7ef8355b63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids></links><search><creatorcontrib>Matsuura, Masana</creatorcontrib><creatorcontrib>Nakajima, Nobuaki</creatorcontrib><creatorcontrib>Ito, Kazuki</creatorcontrib><title>Radiation therapy for bone metastasis of hepatocellular carcinoma</title><title>International journal of clinical oncology</title><description>The efficacy of radiation therapy for bone metastasis of hepatocellular carcinoma was examined retrospectively. The effect of radiation therapy for pain and paresis was evaluated in 38 patients who received planned radiation therapy with the total dose ranging from 26 to 60 Gy. The percentage regression of 14 metastatic bone lesions was calculated by using computed tomography: percentage regression=[(pre-radiation therapy tumor volume--postradiation therapy tumor volume)/pre-radiation therapy tumor volume]×100. The 1-, 2-, and 5-year survival rates of the 38 patients from the start of the radiation therapy were 30% 18%, and 9.0% respectively. The median survival period was 172 days. Pain relief was obtained in 91% of 44 painful bone metastases. No correlation was observed between the percentage regression and the tumor size. Complete regression of bone metastasis was noted in 6 of 14 patients who could be evaluated with computed tomography. Three of the 6 paiients with complete response have survived for more than 6 years after radiation therapy. Radiation therapy is an effective method for palliation of bone metastasis. Although the prognosis of most patients with bone metastasis from hepatocellular carcinoma is poor, some attain longterm survival after treatment.[PUBLICATION ABSTRACT]</description><subject>Liver cancer</subject><subject>Medical prognosis</subject><subject>Metastasis</subject><subject>Radiation therapy</subject><subject>Tomography</subject><issn>1341-9625</issn><issn>1437-7772</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><recordid>eNpFkE1LxDAYhIMouK5e_AUBb0L1zVff5rgurgoLguy9JGnCduk2NWkP---trCAMzBweZmAIuWfwxADw-WUDXGoArS_IgkmBBSLyyzkLyQpdcnVNbnI-ADAsFV-Q1ZdpWjO2safj3icznGiIidrYe3r0o8mz2kxjoHs_mDE633VTZxJ1Jrm2j0dzS66C6bK_-_Ml2W1ed-v3Yvv59rFebQvHSxyLYJ0X0DCGlWu4UVaWWrmguJYoQBmP1mpA5RwD5Dr4SmsR0IdKKGVLsSQP59ohxe_J57E-xCn182LNlAAJCBWfqccz5VLMOflQD6k9mnSqGdS_D9X_D4kfeP5XxQ</recordid><startdate>19980201</startdate><enddate>19980201</enddate><creator>Matsuura, Masana</creator><creator>Nakajima, Nobuaki</creator><creator>Ito, Kazuki</creator><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>19980201</creationdate><title>Radiation therapy for bone metastasis of hepatocellular carcinoma</title><author>Matsuura, Masana ; Nakajima, Nobuaki ; Ito, Kazuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c267t-fbce30d1178cd2a5b4695cf52947305ae7bb9075cc10729fe8993f7ef8355b63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Liver cancer</topic><topic>Medical prognosis</topic><topic>Metastasis</topic><topic>Radiation therapy</topic><topic>Tomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Matsuura, Masana</creatorcontrib><creatorcontrib>Nakajima, Nobuaki</creatorcontrib><creatorcontrib>Ito, Kazuki</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>International journal of clinical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Matsuura, Masana</au><au>Nakajima, Nobuaki</au><au>Ito, Kazuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Radiation therapy for bone metastasis of hepatocellular carcinoma</atitle><jtitle>International journal of clinical oncology</jtitle><date>1998-02-01</date><risdate>1998</risdate><volume>3</volume><issue>1</issue><spage>31</spage><epage>35</epage><pages>31-35</pages><issn>1341-9625</issn><eissn>1437-7772</eissn><abstract>The efficacy of radiation therapy for bone metastasis of hepatocellular carcinoma was examined retrospectively. The effect of radiation therapy for pain and paresis was evaluated in 38 patients who received planned radiation therapy with the total dose ranging from 26 to 60 Gy. The percentage regression of 14 metastatic bone lesions was calculated by using computed tomography: percentage regression=[(pre-radiation therapy tumor volume--postradiation therapy tumor volume)/pre-radiation therapy tumor volume]×100. The 1-, 2-, and 5-year survival rates of the 38 patients from the start of the radiation therapy were 30% 18%, and 9.0% respectively. The median survival period was 172 days. Pain relief was obtained in 91% of 44 painful bone metastases. No correlation was observed between the percentage regression and the tumor size. Complete regression of bone metastasis was noted in 6 of 14 patients who could be evaluated with computed tomography. Three of the 6 paiients with complete response have survived for more than 6 years after radiation therapy. Radiation therapy is an effective method for palliation of bone metastasis. Although the prognosis of most patients with bone metastasis from hepatocellular carcinoma is poor, some attain longterm survival after treatment.[PUBLICATION ABSTRACT]</abstract><cop>Tokyo</cop><pub>Springer Nature B.V</pub><doi>10.1007/BF02490099</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1341-9625
ispartof International journal of clinical oncology, 1998-02, Vol.3 (1), p.31-35
issn 1341-9625
1437-7772
language eng
recordid cdi_proquest_journals_1530407082
source Springer Link
subjects Liver cancer
Medical prognosis
Metastasis
Radiation therapy
Tomography
title Radiation therapy for bone metastasis of hepatocellular carcinoma
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-21T17%3A34%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Radiation%20therapy%20for%20bone%20metastasis%20of%20hepatocellular%20carcinoma&rft.jtitle=International%20journal%20of%20clinical%20oncology&rft.au=Matsuura,%20Masana&rft.date=1998-02-01&rft.volume=3&rft.issue=1&rft.spage=31&rft.epage=35&rft.pages=31-35&rft.issn=1341-9625&rft.eissn=1437-7772&rft_id=info:doi/10.1007/BF02490099&rft_dat=%3Cproquest_cross%3E3319745341%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c267t-fbce30d1178cd2a5b4695cf52947305ae7bb9075cc10729fe8993f7ef8355b63%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1530407082&rft_id=info:pmid/&rfr_iscdi=true