Loading…
Developmental integration in a complex morphological structure: how distinct are the modules in the mouse mandible?
Summary The mouse mandible has long served as a model system for studying the development and evolution of complex morphological structures. We used the methods of geometric morphometrics to reassess the hypothesis that the mandible consists of two separate modules: an anterior part bearing the teet...
Saved in:
| Published in: | Evolution & development 2003-09, Vol.5 (5), p.522-531 |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c5077-4ab6eb0143fed8209bbbe2b637d35c5d33698137cf9223ee53771990565cdf4d3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c5077-4ab6eb0143fed8209bbbe2b637d35c5d33698137cf9223ee53771990565cdf4d3 |
| container_end_page | 531 |
| container_issue | 5 |
| container_start_page | 522 |
| container_title | Evolution & development |
| container_volume | 5 |
| creator | Klingenberg, Christian Peter Mebus, Katharina Auffray, Jean-Christophe |
| description | Summary
The mouse mandible has long served as a model system for studying the development and evolution of complex morphological structures. We used the methods of geometric morphometrics to reassess the hypothesis that the mandible consists of two separate modules: an anterior part bearing the teeth and a posterior part with muscle attachment surfaces and articulating with the skull. The analyses particularly focused on covariation of fluctuating asymmetry, because such covariation is due exclusively to direct interactions between the developmental processes that produce the traits of interest, whereas variation of traits among individuals also reflects other factors. The patterns of fluctuating asymmetry and individual variation were only partly consistent, indicating that developmental processes contribute differentially to variation at different levels. The results were in agreement with the hypothesis that the anterior and posterior parts of the mandible are separate develop‐mental modules. Comparison of all alternative partitions of the landmarks into two contiguous subsets confirmed the hypothesis for the location of the boundary between modules but also underscored that the separation between them is not complete. Modularity is therefore manifest as the relative independence of parts within the framework of overall integration of the mandible as a whole—it is a matter of degrees, not all or nothing. |
| doi_str_mv | 10.1046/j.1525-142X.2003.03057.x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_halsde_00309099v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>73620505</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5077-4ab6eb0143fed8209bbbe2b637d35c5d33698137cf9223ee53771990565cdf4d3</originalsourceid><addsrcrecordid>eNqNkU9v0zAYhyMEYmPwFVBOnEjwnziuOYCmtnSICiQEWsXFcuK3q4sTBzvZum-P01TlysV-bT_vz7KfJEkxyjEqynf7HDPCMlyQTU4QojmiiPH88CS5PB88PdYoYwXeXCQvQtgjhHlBxPPkAhPBUEnRZRIWcA_WdQ20vbKpaXu486o3ro11qtLaNZ2FQ9o43-2cdXemjljo_VD3g4f36c49pNqE3rR1nyoPab-DSOvBQhgjpuUQ4qhabSoLH18mz7bKBnh1mq-Sn5-WP-Y32frb6vP8ep3VDHGeFaoqoUK4oFvQM4JEVVVAqpJyTVnNNKWlmGHK660ghAIwyjkWArGS1XpbaHqVvJ1yd8rKzptG-UfplJE312sZ94IGGT8PCSTEPY74mwnvvPszQOhlY0IN1qoW4gMkpyVBDLEIziaw9i4ED9tzOEZy9CP3ctQgRw1y9COPfuQhtr4-3TFUDeh_jSchEfgwAQ_GwuN_B8vlYnksY0A2BUQncDgHKP9blpxyJm-_ruT31fyWfVls5C_6FzuDr3w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73620505</pqid></control><display><type>article</type><title>Developmental integration in a complex morphological structure: how distinct are the modules in the mouse mandible?</title><source>Wiley-Blackwell Read & Publish Collection</source><creator>Klingenberg, Christian Peter ; Mebus, Katharina ; Auffray, Jean-Christophe</creator><creatorcontrib>Klingenberg, Christian Peter ; Mebus, Katharina ; Auffray, Jean-Christophe</creatorcontrib><description>Summary
The mouse mandible has long served as a model system for studying the development and evolution of complex morphological structures. We used the methods of geometric morphometrics to reassess the hypothesis that the mandible consists of two separate modules: an anterior part bearing the teeth and a posterior part with muscle attachment surfaces and articulating with the skull. The analyses particularly focused on covariation of fluctuating asymmetry, because such covariation is due exclusively to direct interactions between the developmental processes that produce the traits of interest, whereas variation of traits among individuals also reflects other factors. The patterns of fluctuating asymmetry and individual variation were only partly consistent, indicating that developmental processes contribute differentially to variation at different levels. The results were in agreement with the hypothesis that the anterior and posterior parts of the mandible are separate develop‐mental modules. Comparison of all alternative partitions of the landmarks into two contiguous subsets confirmed the hypothesis for the location of the boundary between modules but also underscored that the separation between them is not complete. Modularity is therefore manifest as the relative independence of parts within the framework of overall integration of the mandible as a whole—it is a matter of degrees, not all or nothing.</description><identifier>ISSN: 1520-541X</identifier><identifier>EISSN: 1525-142X</identifier><identifier>DOI: 10.1046/j.1525-142X.2003.03057.x</identifier><identifier>PMID: 12950630</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Inc</publisher><subject>Analysis of Variance ; Animals ; Biodiversity and Ecology ; Body Weights and Measures ; Crosses, Genetic ; Environmental Sciences ; Mandible - growth & development ; Maxillofacial Development - physiology ; Mice - growth & development ; Models, Biological</subject><ispartof>Evolution & development, 2003-09, Vol.5 (5), p.522-531</ispartof><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5077-4ab6eb0143fed8209bbbe2b637d35c5d33698137cf9223ee53771990565cdf4d3</citedby><cites>FETCH-LOGICAL-c5077-4ab6eb0143fed8209bbbe2b637d35c5d33698137cf9223ee53771990565cdf4d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,315,783,787,888,27936,27937</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12950630$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/halsde-00309099$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Klingenberg, Christian Peter</creatorcontrib><creatorcontrib>Mebus, Katharina</creatorcontrib><creatorcontrib>Auffray, Jean-Christophe</creatorcontrib><title>Developmental integration in a complex morphological structure: how distinct are the modules in the mouse mandible?</title><title>Evolution & development</title><addtitle>Evol Dev</addtitle><description>Summary
The mouse mandible has long served as a model system for studying the development and evolution of complex morphological structures. We used the methods of geometric morphometrics to reassess the hypothesis that the mandible consists of two separate modules: an anterior part bearing the teeth and a posterior part with muscle attachment surfaces and articulating with the skull. The analyses particularly focused on covariation of fluctuating asymmetry, because such covariation is due exclusively to direct interactions between the developmental processes that produce the traits of interest, whereas variation of traits among individuals also reflects other factors. The patterns of fluctuating asymmetry and individual variation were only partly consistent, indicating that developmental processes contribute differentially to variation at different levels. The results were in agreement with the hypothesis that the anterior and posterior parts of the mandible are separate develop‐mental modules. Comparison of all alternative partitions of the landmarks into two contiguous subsets confirmed the hypothesis for the location of the boundary between modules but also underscored that the separation between them is not complete. Modularity is therefore manifest as the relative independence of parts within the framework of overall integration of the mandible as a whole—it is a matter of degrees, not all or nothing.</description><subject>Analysis of Variance</subject><subject>Animals</subject><subject>Biodiversity and Ecology</subject><subject>Body Weights and Measures</subject><subject>Crosses, Genetic</subject><subject>Environmental Sciences</subject><subject>Mandible - growth & development</subject><subject>Maxillofacial Development - physiology</subject><subject>Mice - growth & development</subject><subject>Models, Biological</subject><issn>1520-541X</issn><issn>1525-142X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><recordid>eNqNkU9v0zAYhyMEYmPwFVBOnEjwnziuOYCmtnSICiQEWsXFcuK3q4sTBzvZum-P01TlysV-bT_vz7KfJEkxyjEqynf7HDPCMlyQTU4QojmiiPH88CS5PB88PdYoYwXeXCQvQtgjhHlBxPPkAhPBUEnRZRIWcA_WdQ20vbKpaXu486o3ro11qtLaNZ2FQ9o43-2cdXemjljo_VD3g4f36c49pNqE3rR1nyoPab-DSOvBQhgjpuUQ4qhabSoLH18mz7bKBnh1mq-Sn5-WP-Y32frb6vP8ep3VDHGeFaoqoUK4oFvQM4JEVVVAqpJyTVnNNKWlmGHK660ghAIwyjkWArGS1XpbaHqVvJ1yd8rKzptG-UfplJE312sZ94IGGT8PCSTEPY74mwnvvPszQOhlY0IN1qoW4gMkpyVBDLEIziaw9i4ED9tzOEZy9CP3ctQgRw1y9COPfuQhtr4-3TFUDeh_jSchEfgwAQ_GwuN_B8vlYnksY0A2BUQncDgHKP9blpxyJm-_ruT31fyWfVls5C_6FzuDr3w</recordid><startdate>200309</startdate><enddate>200309</enddate><creator>Klingenberg, Christian Peter</creator><creator>Mebus, Katharina</creator><creator>Auffray, Jean-Christophe</creator><general>Blackwell Science Inc</general><general>Wiley</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope></search><sort><creationdate>200309</creationdate><title>Developmental integration in a complex morphological structure: how distinct are the modules in the mouse mandible?</title><author>Klingenberg, Christian Peter ; Mebus, Katharina ; Auffray, Jean-Christophe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5077-4ab6eb0143fed8209bbbe2b637d35c5d33698137cf9223ee53771990565cdf4d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Analysis of Variance</topic><topic>Animals</topic><topic>Biodiversity and Ecology</topic><topic>Body Weights and Measures</topic><topic>Crosses, Genetic</topic><topic>Environmental Sciences</topic><topic>Mandible - growth & development</topic><topic>Maxillofacial Development - physiology</topic><topic>Mice - growth & development</topic><topic>Models, Biological</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Klingenberg, Christian Peter</creatorcontrib><creatorcontrib>Mebus, Katharina</creatorcontrib><creatorcontrib>Auffray, Jean-Christophe</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Evolution & development</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Klingenberg, Christian Peter</au><au>Mebus, Katharina</au><au>Auffray, Jean-Christophe</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Developmental integration in a complex morphological structure: how distinct are the modules in the mouse mandible?</atitle><jtitle>Evolution & development</jtitle><addtitle>Evol Dev</addtitle><date>2003-09</date><risdate>2003</risdate><volume>5</volume><issue>5</issue><spage>522</spage><epage>531</epage><pages>522-531</pages><issn>1520-541X</issn><eissn>1525-142X</eissn><abstract>Summary
The mouse mandible has long served as a model system for studying the development and evolution of complex morphological structures. We used the methods of geometric morphometrics to reassess the hypothesis that the mandible consists of two separate modules: an anterior part bearing the teeth and a posterior part with muscle attachment surfaces and articulating with the skull. The analyses particularly focused on covariation of fluctuating asymmetry, because such covariation is due exclusively to direct interactions between the developmental processes that produce the traits of interest, whereas variation of traits among individuals also reflects other factors. The patterns of fluctuating asymmetry and individual variation were only partly consistent, indicating that developmental processes contribute differentially to variation at different levels. The results were in agreement with the hypothesis that the anterior and posterior parts of the mandible are separate develop‐mental modules. Comparison of all alternative partitions of the landmarks into two contiguous subsets confirmed the hypothesis for the location of the boundary between modules but also underscored that the separation between them is not complete. Modularity is therefore manifest as the relative independence of parts within the framework of overall integration of the mandible as a whole—it is a matter of degrees, not all or nothing.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Inc</pub><pmid>12950630</pmid><doi>10.1046/j.1525-142X.2003.03057.x</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1520-541X |
| ispartof | Evolution & development, 2003-09, Vol.5 (5), p.522-531 |
| issn | 1520-541X 1525-142X |
| language | eng |
| recordid | cdi_hal_primary_oai_HAL_halsde_00309099v1 |
| source | Wiley-Blackwell Read & Publish Collection |
| subjects | Analysis of Variance Animals Biodiversity and Ecology Body Weights and Measures Crosses, Genetic Environmental Sciences Mandible - growth & development Maxillofacial Development - physiology Mice - growth & development Models, Biological |
| title | Developmental integration in a complex morphological structure: how distinct are the modules in the mouse mandible? |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-11-12T07%3A44%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Developmental%20integration%20in%20a%20complex%20morphological%20structure:%20how%20distinct%20are%20the%20modules%20in%20the%20mouse%20mandible?&rft.jtitle=Evolution%20&%20development&rft.au=Klingenberg,%20Christian%20Peter&rft.date=2003-09&rft.volume=5&rft.issue=5&rft.spage=522&rft.epage=531&rft.pages=522-531&rft.issn=1520-541X&rft.eissn=1525-142X&rft_id=info:doi/10.1046/j.1525-142X.2003.03057.x&rft_dat=%3Cproquest_hal_p%3E73620505%3C/proquest_hal_p%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c5077-4ab6eb0143fed8209bbbe2b637d35c5d33698137cf9223ee53771990565cdf4d3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=73620505&rft_id=info:pmid/12950630&rfr_iscdi=true |