Incidence, survival and geoepidemiological analysis of meningiomas and glioblastomas in the province of Catania during the 2003–2016 period

Meningiomas are the most common primary brain tumors, followed by glioblastomas. Nevertheless, no previous studies have been conducted to evaluate the epidemiology of meningiomas and glioblastomas in the southern region of Italy. Thus, the aim of our study was to evaluate incidence, temporal trend a...

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Bibliographic Details
Published in:Environmental research 2021-09, Vol.200, p.111286-111286, Article 111286
Main Authors: Chebil, Chaima, Boumediene, Farid, Cicero, Calogero Edoardo, Rascunà, Cristina, Di Prima, Alessia, Maria Torrisi, Antonietta Alfia, Torrisi, Antonina, Sciacca, Salvatore, Zappia, Mario, Preux, Pierre-Marie, Ferrante, Margherita, Nicoletti, Alessandra
Format: Article
Language:English
Subjects:
Cancer registry
Cluster
Glioblastoma
Incidence
Life Sciences
Meningioma
Santé publique et épidémiologie
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Summary:Meningiomas are the most common primary brain tumors, followed by glioblastomas. Nevertheless, no previous studies have been conducted to evaluate the epidemiology of meningiomas and glioblastomas in the southern region of Italy. Thus, the aim of our study was to evaluate incidence, temporal trend and survival rate of meningiomas and glioblastomas in the province of Catania during the study period. Moreover, a geoepidemiological analysis was performed in order to identify possible geographical and temporal clusters. All subjects with meningiomas and glioblastomas diagnosed from 2003 to 2016 in the province of Catania were collected, using the local cancer registry. Incidence rate (IR) was calculated by gender, age-groups and tumor behavior. Temporal changes in incidence trend were assessed using a Joinpoint regression analysis while survival analysis was performed using Kaplan-Meier method. Cluster analysis was performed using Kulldorff’s spatial scan statistic. In the province of Catania, a total of 1488 cases of meningiomas and 443 cases of glioblastomas were identified from 2003 to 2016, with an IR of 9.8/100,000 person-years (95%CI 9.3–10.3) and 2.9/100,000 person-years (95%CI 2.7–3.2), respectively. Meningiomas were more common among women (p-value
ISSN:0013-9351
1096-0953
DOI:10.1016/j.envres.2021.111286