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The prevalence of inflammatory sacroiliitis assessed on magnetic resonance imaging of inflammatory bowel disease: a retrospective study performed on 186 patients
Summary Background Magnetic resonance imaging (MRI) colonography or enterography is increasingly used to assess disease activity and complications in inflammatory bowel disease (IBD). However, no study has evaluated the role of this imaging technique to assess sacroiliitis. Aim The primary objective...
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| Published in: | Alimentary pharmacology & therapeutics 2014-05, Vol.39 (9), p.957-962 |
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| container_title | Alimentary pharmacology & therapeutics |
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| creator | Leclerc‐Jacob, S. Lux, G. Rat, A. C. Laurent, V. Blum, A. Chary‐Valckenaere, I. Peyrin‐Biroulet, L. Loeuille, D. |
| description | Summary
Background
Magnetic resonance imaging (MRI) colonography or enterography is increasingly used to assess disease activity and complications in inflammatory bowel disease (IBD). However, no study has evaluated the role of this imaging technique to assess sacroiliitis.
Aim
The primary objective was to assess the prevalence of inflammatory sacroiliitis on MRI performed for IBD investigation. The secondary aim was to elucidate clinico‐biological factors associated with the presence of sacroiliitis.
Methods
This study was performed on 186 patients suffering from IBD followed in a gastroenterology department between 2004 and 2011: 131 with Crohn's disease and 55 with ulcerative colitis. Clinico‐biological and endoscopic data were collected and MR enterography or colonography was performed to assess IBD activity on axial and coronal fat suppressed injected T1‐weighted sequences. On MRI, sacroiliitis was scored blindly by two independent readers according to ASAS (Assessment of SpondyloArthritis international Society) criteria.
Results
The prevalence of inflammatory sacroiliitis was 16.7% (n = 31). Sacroiliitis was bilateral in 14 cases and unilateral in 17 cases. The sacroiliac joints were considered normal in 144 cases and doubtful in 11 cases. Older age and female gender were significantly associated with the presence of sacroiliitis. Other factors such as type of IBD, disease duration and localisation of IBD, surgery history, biological inflammation, bowel disease activity and treatment were not associated with sacroiliitis.
Conclusion
Inflammatory sacroiliitis was evidenced by MRI in 16.7% in patients suffering from IBD. Added to clinico‐biological data, MRI analysis should contribute to an earlier diagnosis of axial spondylarthritis in patients with IBD. |
| doi_str_mv | 10.1111/apt.12680 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_01453202v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1687661087</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4880-9ec0e8d22e0e561d35dfb9b61898270b5f6993bd4fa757a584340d72e8a2155f3</originalsourceid><addsrcrecordid>eNqFkc-O0zAQxi0EYsvCgRdAviDBIbu2EzsOt2oFLFIlOJRzNEnGu0ZOHGy3qz4Ob4pLSjkghDWSpdFvvvnzEfKSsyue3zXM6YoLpdkjsuKlkoVgpXpMVkyophCalxfkWYzfGGOqZuIpuRCVbEom2Yr82N4jnQPuweHUI_WG2sk4GEdIPhxohD5466xNNlKIEXMM1E90hLsJk-1pwOgnONbanLPT3V8anX9ARwcbESK-o5BLUvBxxj7ZPdKYdsOBzhiMD-MizrWiMySLU4rPyRMDLuKL039Jvn54v725LTafP366WW-KvtKaFQ32DPUgBDKUig-lHEzXdIrrRouaddKopim7oTJQyxqkrsqKDbVADYJLacpL8nbRvQfXziEvEw6tB9verjftMcd4JUvBxJ5n9s3CzsF_32FM7Whjj87BhH4XW650rRRnuv4_KrmQUos83HmCfPIYA5rzGJy1R6PbbHT7y-jMvjrJ7rp8tDP529kMvD4BEHtwJmSLbPzD6bx-VVeZu164B-vw8O-O7frLdmn9E5fPwLY</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1512558299</pqid></control><display><type>article</type><title>The prevalence of inflammatory sacroiliitis assessed on magnetic resonance imaging of inflammatory bowel disease: a retrospective study performed on 186 patients</title><source>Wiley-Blackwell Journals</source><creator>Leclerc‐Jacob, S. ; Lux, G. ; Rat, A. C. ; Laurent, V. ; Blum, A. ; Chary‐Valckenaere, I. ; Peyrin‐Biroulet, L. ; Loeuille, D.</creator><creatorcontrib>Leclerc‐Jacob, S. ; Lux, G. ; Rat, A. C. ; Laurent, V. ; Blum, A. ; Chary‐Valckenaere, I. ; Peyrin‐Biroulet, L. ; Loeuille, D.</creatorcontrib><description>Summary
Background
Magnetic resonance imaging (MRI) colonography or enterography is increasingly used to assess disease activity and complications in inflammatory bowel disease (IBD). However, no study has evaluated the role of this imaging technique to assess sacroiliitis.
Aim
The primary objective was to assess the prevalence of inflammatory sacroiliitis on MRI performed for IBD investigation. The secondary aim was to elucidate clinico‐biological factors associated with the presence of sacroiliitis.
Methods
This study was performed on 186 patients suffering from IBD followed in a gastroenterology department between 2004 and 2011: 131 with Crohn's disease and 55 with ulcerative colitis. Clinico‐biological and endoscopic data were collected and MR enterography or colonography was performed to assess IBD activity on axial and coronal fat suppressed injected T1‐weighted sequences. On MRI, sacroiliitis was scored blindly by two independent readers according to ASAS (Assessment of SpondyloArthritis international Society) criteria.
Results
The prevalence of inflammatory sacroiliitis was 16.7% (n = 31). Sacroiliitis was bilateral in 14 cases and unilateral in 17 cases. The sacroiliac joints were considered normal in 144 cases and doubtful in 11 cases. Older age and female gender were significantly associated with the presence of sacroiliitis. Other factors such as type of IBD, disease duration and localisation of IBD, surgery history, biological inflammation, bowel disease activity and treatment were not associated with sacroiliitis.
Conclusion
Inflammatory sacroiliitis was evidenced by MRI in 16.7% in patients suffering from IBD. Added to clinico‐biological data, MRI analysis should contribute to an earlier diagnosis of axial spondylarthritis in patients with IBD.</description><identifier>ISSN: 0269-2813</identifier><identifier>EISSN: 1365-2036</identifier><identifier>DOI: 10.1111/apt.12680</identifier><identifier>PMID: 24593050</identifier><language>eng</language><publisher>Oxford: Blackwell</publisher><subject>Adult ; Biochemistry ; Biochemistry, Molecular Biology ; Biological and medical sciences ; Colitis, Ulcerative - complications ; Colitis, Ulcerative - physiopathology ; Crohn Disease - complications ; Crohn Disease - physiopathology ; Early Diagnosis ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Human health and pathology ; Humans ; Life Sciences ; Magnetic Resonance Imaging - methods ; Male ; Medical sciences ; Middle Aged ; Other diseases. Semiology ; Prevalence ; Retrospective Studies ; Risk Factors ; Sacroiliac Joint - pathology ; Sacroiliitis - diagnosis ; Sacroiliitis - epidemiology ; Sacroiliitis - etiology ; Spondylarthritis - diagnosis ; Spondylarthritis - etiology ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus ; Young Adult</subject><ispartof>Alimentary pharmacology & therapeutics, 2014-05, Vol.39 (9), p.957-962</ispartof><rights>2014 John Wiley & Sons Ltd</rights><rights>2015 INIST-CNRS</rights><rights>2014 John Wiley & Sons Ltd.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4880-9ec0e8d22e0e561d35dfb9b61898270b5f6993bd4fa757a584340d72e8a2155f3</citedby><cites>FETCH-LOGICAL-c4880-9ec0e8d22e0e561d35dfb9b61898270b5f6993bd4fa757a584340d72e8a2155f3</cites><orcidid>0000-0001-8204-5701 ; 0000-0003-2536-6618</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fapt.12680$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fapt.12680$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,315,786,790,891,27957,27958,50923,51032</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28340474$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24593050$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.univ-lorraine.fr/hal-01453202$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Leclerc‐Jacob, S.</creatorcontrib><creatorcontrib>Lux, G.</creatorcontrib><creatorcontrib>Rat, A. C.</creatorcontrib><creatorcontrib>Laurent, V.</creatorcontrib><creatorcontrib>Blum, A.</creatorcontrib><creatorcontrib>Chary‐Valckenaere, I.</creatorcontrib><creatorcontrib>Peyrin‐Biroulet, L.</creatorcontrib><creatorcontrib>Loeuille, D.</creatorcontrib><title>The prevalence of inflammatory sacroiliitis assessed on magnetic resonance imaging of inflammatory bowel disease: a retrospective study performed on 186 patients</title><title>Alimentary pharmacology & therapeutics</title><addtitle>Aliment Pharmacol Ther</addtitle><description>Summary
Background
Magnetic resonance imaging (MRI) colonography or enterography is increasingly used to assess disease activity and complications in inflammatory bowel disease (IBD). However, no study has evaluated the role of this imaging technique to assess sacroiliitis.
Aim
The primary objective was to assess the prevalence of inflammatory sacroiliitis on MRI performed for IBD investigation. The secondary aim was to elucidate clinico‐biological factors associated with the presence of sacroiliitis.
Methods
This study was performed on 186 patients suffering from IBD followed in a gastroenterology department between 2004 and 2011: 131 with Crohn's disease and 55 with ulcerative colitis. Clinico‐biological and endoscopic data were collected and MR enterography or colonography was performed to assess IBD activity on axial and coronal fat suppressed injected T1‐weighted sequences. On MRI, sacroiliitis was scored blindly by two independent readers according to ASAS (Assessment of SpondyloArthritis international Society) criteria.
Results
The prevalence of inflammatory sacroiliitis was 16.7% (n = 31). Sacroiliitis was bilateral in 14 cases and unilateral in 17 cases. The sacroiliac joints were considered normal in 144 cases and doubtful in 11 cases. Older age and female gender were significantly associated with the presence of sacroiliitis. Other factors such as type of IBD, disease duration and localisation of IBD, surgery history, biological inflammation, bowel disease activity and treatment were not associated with sacroiliitis.
Conclusion
Inflammatory sacroiliitis was evidenced by MRI in 16.7% in patients suffering from IBD. Added to clinico‐biological data, MRI analysis should contribute to an earlier diagnosis of axial spondylarthritis in patients with IBD.</description><subject>Adult</subject><subject>Biochemistry</subject><subject>Biochemistry, Molecular Biology</subject><subject>Biological and medical sciences</subject><subject>Colitis, Ulcerative - complications</subject><subject>Colitis, Ulcerative - physiopathology</subject><subject>Crohn Disease - complications</subject><subject>Crohn Disease - physiopathology</subject><subject>Early Diagnosis</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Human health and pathology</subject><subject>Humans</subject><subject>Life Sciences</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Other diseases. Semiology</subject><subject>Prevalence</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Sacroiliac Joint - pathology</subject><subject>Sacroiliitis - diagnosis</subject><subject>Sacroiliitis - epidemiology</subject><subject>Sacroiliitis - etiology</subject><subject>Spondylarthritis - diagnosis</subject><subject>Spondylarthritis - etiology</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><subject>Young Adult</subject><issn>0269-2813</issn><issn>1365-2036</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqFkc-O0zAQxi0EYsvCgRdAviDBIbu2EzsOt2oFLFIlOJRzNEnGu0ZOHGy3qz4Ob4pLSjkghDWSpdFvvvnzEfKSsyue3zXM6YoLpdkjsuKlkoVgpXpMVkyophCalxfkWYzfGGOqZuIpuRCVbEom2Yr82N4jnQPuweHUI_WG2sk4GEdIPhxohD5466xNNlKIEXMM1E90hLsJk-1pwOgnONbanLPT3V8anX9ARwcbESK-o5BLUvBxxj7ZPdKYdsOBzhiMD-MizrWiMySLU4rPyRMDLuKL039Jvn54v725LTafP366WW-KvtKaFQ32DPUgBDKUig-lHEzXdIrrRouaddKopim7oTJQyxqkrsqKDbVADYJLacpL8nbRvQfXziEvEw6tB9verjftMcd4JUvBxJ5n9s3CzsF_32FM7Whjj87BhH4XW650rRRnuv4_KrmQUos83HmCfPIYA5rzGJy1R6PbbHT7y-jMvjrJ7rp8tDP529kMvD4BEHtwJmSLbPzD6bx-VVeZu164B-vw8O-O7frLdmn9E5fPwLY</recordid><startdate>201405</startdate><enddate>201405</enddate><creator>Leclerc‐Jacob, S.</creator><creator>Lux, G.</creator><creator>Rat, A. C.</creator><creator>Laurent, V.</creator><creator>Blum, A.</creator><creator>Chary‐Valckenaere, I.</creator><creator>Peyrin‐Biroulet, L.</creator><creator>Loeuille, D.</creator><general>Blackwell</general><general>Wiley</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7U7</scope><scope>C1K</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0001-8204-5701</orcidid><orcidid>https://orcid.org/0000-0003-2536-6618</orcidid></search><sort><creationdate>201405</creationdate><title>The prevalence of inflammatory sacroiliitis assessed on magnetic resonance imaging of inflammatory bowel disease: a retrospective study performed on 186 patients</title><author>Leclerc‐Jacob, S. ; Lux, G. ; Rat, A. C. ; Laurent, V. ; Blum, A. ; Chary‐Valckenaere, I. ; Peyrin‐Biroulet, L. ; Loeuille, D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4880-9ec0e8d22e0e561d35dfb9b61898270b5f6993bd4fa757a584340d72e8a2155f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Biochemistry</topic><topic>Biochemistry, Molecular Biology</topic><topic>Biological and medical sciences</topic><topic>Colitis, Ulcerative - complications</topic><topic>Colitis, Ulcerative - physiopathology</topic><topic>Crohn Disease - complications</topic><topic>Crohn Disease - physiopathology</topic><topic>Early Diagnosis</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Human health and pathology</topic><topic>Humans</topic><topic>Life Sciences</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Other diseases. Semiology</topic><topic>Prevalence</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Sacroiliac Joint - pathology</topic><topic>Sacroiliitis - diagnosis</topic><topic>Sacroiliitis - epidemiology</topic><topic>Sacroiliitis - etiology</topic><topic>Spondylarthritis - diagnosis</topic><topic>Spondylarthritis - etiology</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Leclerc‐Jacob, S.</creatorcontrib><creatorcontrib>Lux, G.</creatorcontrib><creatorcontrib>Rat, A. C.</creatorcontrib><creatorcontrib>Laurent, V.</creatorcontrib><creatorcontrib>Blum, A.</creatorcontrib><creatorcontrib>Chary‐Valckenaere, I.</creatorcontrib><creatorcontrib>Peyrin‐Biroulet, L.</creatorcontrib><creatorcontrib>Loeuille, D.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Alimentary pharmacology & therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Leclerc‐Jacob, S.</au><au>Lux, G.</au><au>Rat, A. C.</au><au>Laurent, V.</au><au>Blum, A.</au><au>Chary‐Valckenaere, I.</au><au>Peyrin‐Biroulet, L.</au><au>Loeuille, D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The prevalence of inflammatory sacroiliitis assessed on magnetic resonance imaging of inflammatory bowel disease: a retrospective study performed on 186 patients</atitle><jtitle>Alimentary pharmacology & therapeutics</jtitle><addtitle>Aliment Pharmacol Ther</addtitle><date>2014-05</date><risdate>2014</risdate><volume>39</volume><issue>9</issue><spage>957</spage><epage>962</epage><pages>957-962</pages><issn>0269-2813</issn><eissn>1365-2036</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>Summary
Background
Magnetic resonance imaging (MRI) colonography or enterography is increasingly used to assess disease activity and complications in inflammatory bowel disease (IBD). However, no study has evaluated the role of this imaging technique to assess sacroiliitis.
Aim
The primary objective was to assess the prevalence of inflammatory sacroiliitis on MRI performed for IBD investigation. The secondary aim was to elucidate clinico‐biological factors associated with the presence of sacroiliitis.
Methods
This study was performed on 186 patients suffering from IBD followed in a gastroenterology department between 2004 and 2011: 131 with Crohn's disease and 55 with ulcerative colitis. Clinico‐biological and endoscopic data were collected and MR enterography or colonography was performed to assess IBD activity on axial and coronal fat suppressed injected T1‐weighted sequences. On MRI, sacroiliitis was scored blindly by two independent readers according to ASAS (Assessment of SpondyloArthritis international Society) criteria.
Results
The prevalence of inflammatory sacroiliitis was 16.7% (n = 31). Sacroiliitis was bilateral in 14 cases and unilateral in 17 cases. The sacroiliac joints were considered normal in 144 cases and doubtful in 11 cases. Older age and female gender were significantly associated with the presence of sacroiliitis. Other factors such as type of IBD, disease duration and localisation of IBD, surgery history, biological inflammation, bowel disease activity and treatment were not associated with sacroiliitis.
Conclusion
Inflammatory sacroiliitis was evidenced by MRI in 16.7% in patients suffering from IBD. Added to clinico‐biological data, MRI analysis should contribute to an earlier diagnosis of axial spondylarthritis in patients with IBD.</abstract><cop>Oxford</cop><pub>Blackwell</pub><pmid>24593050</pmid><doi>10.1111/apt.12680</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-8204-5701</orcidid><orcidid>https://orcid.org/0000-0003-2536-6618</orcidid></addata></record> |
| fulltext | fulltext |
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| ispartof | Alimentary pharmacology & therapeutics, 2014-05, Vol.39 (9), p.957-962 |
| issn | 0269-2813 1365-2036 |
| language | eng |
| recordid | cdi_hal_primary_oai_HAL_hal_01453202v1 |
| source | Wiley-Blackwell Journals |
| subjects | Adult Biochemistry Biochemistry, Molecular Biology Biological and medical sciences Colitis, Ulcerative - complications Colitis, Ulcerative - physiopathology Crohn Disease - complications Crohn Disease - physiopathology Early Diagnosis Female Gastroenterology. Liver. Pancreas. Abdomen Human health and pathology Humans Life Sciences Magnetic Resonance Imaging - methods Male Medical sciences Middle Aged Other diseases. Semiology Prevalence Retrospective Studies Risk Factors Sacroiliac Joint - pathology Sacroiliitis - diagnosis Sacroiliitis - epidemiology Sacroiliitis - etiology Spondylarthritis - diagnosis Spondylarthritis - etiology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Young Adult |
| title | The prevalence of inflammatory sacroiliitis assessed on magnetic resonance imaging of inflammatory bowel disease: a retrospective study performed on 186 patients |
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