C-REACTIVE PROTEIN LEVELS AND THE SEVERITY OF COVID-19

Objective: To compare the C-reactive proteinlevels in different groups of COVID-19 patients to assess disease severity. Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital Kohat, from Apr 2020 to Jun2020. Methodology: Forty fiveConfirmed cases of COVID-19 pat...

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Published in:Pakistan Armed Forces medical journal 2020-08, Vol.70 (COVID-19 (2)), p.S603-607
Main Authors: Mirza Waseem Javed, Muhammad Anwar, Tariq Mehmood Bangash, Rizwan Ul Haq Satti, Mehar Rehman, Uzair Ijaz Malik
Format: Article
Language:English
Subjects:
C-reactive protein
Coronaviruses
COVID-19
disease severity classification
Health aspects
Heart diseases
Pneumonia
Proteins
Severe acute respiratory syndrome
Virus diseases
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container_end_page 607
container_issue COVID-19 (2)
container_start_page S603
container_title Pakistan Armed Forces medical journal
container_volume 70
creator Mirza Waseem Javed
Muhammad Anwar
Tariq Mehmood Bangash
Rizwan Ul Haq Satti
Mehar Rehman
Uzair Ijaz Malik
description Objective: To compare the C-reactive proteinlevels in different groups of COVID-19 patients to assess disease severity. Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital Kohat, from Apr 2020 to Jun2020. Methodology: Forty fiveConfirmed cases of COVID-19 patients were included by non-probability consecutive sampling. Patients were divided into five groups (Asymptomatic, Mild, Moderate, Severe and Critical). Serum sample for C -reactiveprotein levels were collected at presentation and compared in different clinical groups by Paired sample “t” test andoneway Anova(Post Hoc LSD). Result: Out of 45 cases in our study28 (62.2%) were male and 17 (37.8%) were female. Mean age of patients was 51.96 ± 16 and mean C-reactiveproteinlevels were 76.61± 75 mg/L. When compared by paired sample t-test C-reactive proteinlevels were: higherin the mild patient group than asymptomatic group, higher inthe moderate groupthan mild group, higherin severe group than moderate group and those in the critical group were higherthan those in the severe group. The difference was statistically significant with p-value
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Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital Kohat, from Apr 2020 to Jun2020. Methodology: Forty fiveConfirmed cases of COVID-19 patients were included by non-probability consecutive sampling. Patients were divided into five groups (Asymptomatic, Mild, Moderate, Severe and Critical). Serum sample for C -reactiveprotein levels were collected at presentation and compared in different clinical groups by Paired sample “t” test andoneway Anova(Post Hoc LSD). Result: Out of 45 cases in our study28 (62.2%) were male and 17 (37.8%) were female. Mean age of patients was 51.96 ± 16 and mean C-reactiveproteinlevels were 76.61± 75 mg/L. When compared by paired sample t-test C-reactive proteinlevels were: higherin the mild patient group than asymptomatic group, higher inthe moderate groupthan mild group, higherin severe group than moderate group and those in the critical group were higherthan those in the severe group. The difference was statistically significant with p-value &lt;0.05 in each group. Conclusion: C-reactive proteinlevelswerelowest in asymptomatic and highest in critical patients inearly COVID-19. This may help guide management.</description><identifier>ISSN: 0030-9648</identifier><identifier>EISSN: 2411-8842</identifier><language>eng</language><publisher>Knowledge Bylanes</publisher><subject>C-reactive protein ; Coronaviruses ; COVID-19 ; disease severity classification ; Health aspects ; Heart diseases ; Pneumonia ; Proteins ; Severe acute respiratory syndrome ; Virus diseases</subject><ispartof>Pakistan Armed Forces medical journal, 2020-08, Vol.70 (COVID-19 (2)), p.S603-607</ispartof><rights>COPYRIGHT 2020 Knowledge Bylanes</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,783,787</link.rule.ids></links><search><creatorcontrib>Mirza Waseem Javed</creatorcontrib><creatorcontrib>Muhammad Anwar</creatorcontrib><creatorcontrib>Tariq Mehmood Bangash</creatorcontrib><creatorcontrib>Rizwan Ul Haq Satti</creatorcontrib><creatorcontrib>Mehar Rehman</creatorcontrib><creatorcontrib>Uzair Ijaz Malik</creatorcontrib><title>C-REACTIVE PROTEIN LEVELS AND THE SEVERITY OF COVID-19</title><title>Pakistan Armed Forces medical journal</title><description>Objective: To compare the C-reactive proteinlevels in different groups of COVID-19 patients to assess disease severity. Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital Kohat, from Apr 2020 to Jun2020. Methodology: Forty fiveConfirmed cases of COVID-19 patients were included by non-probability consecutive sampling. Patients were divided into five groups (Asymptomatic, Mild, Moderate, Severe and Critical). Serum sample for C -reactiveprotein levels were collected at presentation and compared in different clinical groups by Paired sample “t” test andoneway Anova(Post Hoc LSD). Result: Out of 45 cases in our study28 (62.2%) were male and 17 (37.8%) were female. Mean age of patients was 51.96 ± 16 and mean C-reactiveproteinlevels were 76.61± 75 mg/L. When compared by paired sample t-test C-reactive proteinlevels were: higherin the mild patient group than asymptomatic group, higher inthe moderate groupthan mild group, higherin severe group than moderate group and those in the critical group were higherthan those in the severe group. The difference was statistically significant with p-value &lt;0.05 in each group. Conclusion: C-reactive proteinlevelswerelowest in asymptomatic and highest in critical patients inearly COVID-19. 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subjects C-reactive protein
Coronaviruses
COVID-19
disease severity classification
Health aspects
Heart diseases
Pneumonia
Proteins
Severe acute respiratory syndrome
Virus diseases
title C-REACTIVE PROTEIN LEVELS AND THE SEVERITY OF COVID-19
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