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Local anesthetic systemic toxicity

Local anesthetic systemic toxicity (LAST) is a rare yet devastating complication from the administration of local anesthesia. The ability to recognize and treat LAST is critical for clinicians who administer these drugs. The authors reviewed the literature on the mechanism, treatment, and prevention...

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Published in:Aesthetic surgery journal 2014-09, Vol.34 (7), p.1111-1119
Main Authors: Dickerson, David M, Apfelbaum, Jeffrey L
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Language:English
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description Local anesthetic systemic toxicity (LAST) is a rare yet devastating complication from the administration of local anesthesia. The ability to recognize and treat LAST is critical for clinicians who administer these drugs. The authors reviewed the literature on the mechanism, treatment, and prevention of LAST, with the goal of proposing a practical method for its management.
doi_str_mv 10.1177/1090820X14543102
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source AUTh Library subscriptions: Oxford University Press
subjects Anesthesia, Local - adverse effects
Anesthesia, Local - methods
Anesthesia, Local - mortality
Anesthetics, Local - adverse effects
Animals
Humans
Patient Safety
Poisoning - diagnosis
Poisoning - etiology
Poisoning - mortality
Poisoning - prevention & control
Poisoning - therapy
Prognosis
Risk Assessment
Risk Factors
title Local anesthetic systemic toxicity
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