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Extensive burns caused by the abusive use of photosensitizing agents
Psoralens are photosensitizing agents used in dermatology as reinforcements in psoralen ultraviolet A-range therapy. We report observations of 14 young women hospitalized for severe burns caused by abusive use of psoralens. The burns were of superficial and deep second-degree depth and covered more...
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Published in: | Journal of burn care & rehabilitation 1997-07, Vol.18 (4), p.321-325 |
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container_title | Journal of burn care & rehabilitation |
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creator | BRAYE, F LATARJET, J FOYATIER, J. L COMPARIN, J. P TRANCHAND, P BOUCAUD, C |
description | Psoralens are photosensitizing agents used in dermatology as reinforcements in psoralen ultraviolet A-range therapy. We report observations of 14 young women hospitalized for severe burns caused by abusive use of psoralens. The burns were of superficial and deep second-degree depth and covered more than 76% of the body surface on average. All patients needed fluid resuscitation. Hospital stay was 11 days on average. Healing was obtained without skin grafting in all cases. Among the six patients who responded to the mailed questionnaire, negative effects are now present in all patients as inflammatory peaks. Two patients have esthetic sequelae such as dyschromia and scars. The misuse of photosensitizing agents poses many problems. These accidents are very expensive. The largeness of the burned surface can involve a fatal prognosis. And finally, one can suspect that a much larger portion of the population regularly uses these products without any serious accident. In this case carcinogenesis can be expected. |
doi_str_mv | 10.1097/00004630-199707000-00008 |
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The largeness of the burned surface can involve a fatal prognosis. And finally, one can suspect that a much larger portion of the population regularly uses these products without any serious accident. In this case carcinogenesis can be expected.</description><identifier>ISSN: 0273-8481</identifier><identifier>EISSN: 1534-5939</identifier><identifier>DOI: 10.1097/00004630-199707000-00008</identifier><identifier>PMID: 9261698</identifier><identifier>CODEN: JBCRD2</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Burns ; Burns - etiology ; Burns - physiopathology ; Female ; Fluid Therapy ; Hospitalization - statistics & numerical data ; Humans ; Length of Stay ; Medical sciences ; Methoxsalen - adverse effects ; Middle Aged ; Photosensitizing Agents - adverse effects ; Substance-Related Disorders ; Traumas. 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L</creatorcontrib><creatorcontrib>COMPARIN, J. P</creatorcontrib><creatorcontrib>TRANCHAND, P</creatorcontrib><creatorcontrib>BOUCAUD, C</creatorcontrib><title>Extensive burns caused by the abusive use of photosensitizing agents</title><title>Journal of burn care & rehabilitation</title><addtitle>J Burn Care Rehabil</addtitle><description>Psoralens are photosensitizing agents used in dermatology as reinforcements in psoralen ultraviolet A-range therapy. We report observations of 14 young women hospitalized for severe burns caused by abusive use of psoralens. The burns were of superficial and deep second-degree depth and covered more than 76% of the body surface on average. All patients needed fluid resuscitation. Hospital stay was 11 days on average. Healing was obtained without skin grafting in all cases. Among the six patients who responded to the mailed questionnaire, negative effects are now present in all patients as inflammatory peaks. Two patients have esthetic sequelae such as dyschromia and scars. The misuse of photosensitizing agents poses many problems. These accidents are very expensive. The largeness of the burned surface can involve a fatal prognosis. And finally, one can suspect that a much larger portion of the population regularly uses these products without any serious accident. In this case carcinogenesis can be expected.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Burns</subject><subject>Burns - etiology</subject><subject>Burns - physiopathology</subject><subject>Female</subject><subject>Fluid Therapy</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Length of Stay</subject><subject>Medical sciences</subject><subject>Methoxsalen - adverse effects</subject><subject>Middle Aged</subject><subject>Photosensitizing Agents - adverse effects</subject><subject>Substance-Related Disorders</subject><subject>Traumas. 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P</creator><creator>TRANCHAND, P</creator><creator>BOUCAUD, C</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>199707</creationdate><title>Extensive burns caused by the abusive use of photosensitizing agents</title><author>BRAYE, F ; LATARJET, J ; FOYATIER, J. L ; COMPARIN, J. 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Diseases due to physical agents</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BRAYE, F</creatorcontrib><creatorcontrib>LATARJET, J</creatorcontrib><creatorcontrib>FOYATIER, J. L</creatorcontrib><creatorcontrib>COMPARIN, J. P</creatorcontrib><creatorcontrib>TRANCHAND, P</creatorcontrib><creatorcontrib>BOUCAUD, C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Journal of burn care & rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BRAYE, F</au><au>LATARJET, J</au><au>FOYATIER, J. L</au><au>COMPARIN, J. P</au><au>TRANCHAND, P</au><au>BOUCAUD, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Extensive burns caused by the abusive use of photosensitizing agents</atitle><jtitle>Journal of burn care & rehabilitation</jtitle><addtitle>J Burn Care Rehabil</addtitle><date>1997-07</date><risdate>1997</risdate><volume>18</volume><issue>4</issue><spage>321</spage><epage>325</epage><pages>321-325</pages><issn>0273-8481</issn><eissn>1534-5939</eissn><coden>JBCRD2</coden><abstract>Psoralens are photosensitizing agents used in dermatology as reinforcements in psoralen ultraviolet A-range therapy. We report observations of 14 young women hospitalized for severe burns caused by abusive use of psoralens. The burns were of superficial and deep second-degree depth and covered more than 76% of the body surface on average. All patients needed fluid resuscitation. Hospital stay was 11 days on average. Healing was obtained without skin grafting in all cases. Among the six patients who responded to the mailed questionnaire, negative effects are now present in all patients as inflammatory peaks. Two patients have esthetic sequelae such as dyschromia and scars. The misuse of photosensitizing agents poses many problems. These accidents are very expensive. The largeness of the burned surface can involve a fatal prognosis. And finally, one can suspect that a much larger portion of the population regularly uses these products without any serious accident. In this case carcinogenesis can be expected.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>9261698</pmid><doi>10.1097/00004630-199707000-00008</doi><tpages>5</tpages></addata></record> |
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source | Oxford Journals Online |
subjects | Adolescent Adult Biological and medical sciences Burns Burns - etiology Burns - physiopathology Female Fluid Therapy Hospitalization - statistics & numerical data Humans Length of Stay Medical sciences Methoxsalen - adverse effects Middle Aged Photosensitizing Agents - adverse effects Substance-Related Disorders Traumas. Diseases due to physical agents Treatment Outcome |
title | Extensive burns caused by the abusive use of photosensitizing agents |
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