Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register

by Hilker, Rikke, Helenius, Dorte, Fagerlund, Birgitte, Skytthe, Axel, Christensen, Kaare, Werge, Thomas M., Nordentoft, Merete, Glenthøj, Birte
Published in Biological psychiatry (1969)

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

by Gandal, Michael J, Haney, Jillian R, Parikshak, Neelroop N, Leppa, Virpi, Ramaswami, Gokul, Hartl, Chris, Schork, Andrew J, Appadurai, Vivek, Buil, Alfonso, Werge, Thomas M, Liu, Chunyu, White, Kevin P, Horvath, Steve, Geschwind, Daniel H
Published in Science (American Association for the Advancement of Science)

Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants

by Satterstrom, F Kyle, Walters, Raymond K, Singh, Tarjinder, Wigdor, Emilie M, Lescai, Francesco, Demontis, Ditte, Kosmicki, Jack A, Grove, Jakob, Stevens, Christine, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Palmer, Duncan S, Maller, Julian B, Nordentoft, Merete, Mors, Ole, Robinson, Elise B, Hougaard, David M, Werge, Thomas M, Bo Mortensen, Preben, Neale, Benjamin M, Børglum, Anders D, Daly, Mark J
Published in Nature neuroscience

Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of night owl/LZTR1 and NF1 in GABAergic sleep control

by Maurer, Gianna W, Malita, Alina, Nagy, Stanislav, Koyama, Takashi, Werge, Thomas M, Halberg, Kenneth A, Texada, Michael J, Rewitz, Kim
Published in PLoS genetics

AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance

by Nagy, Stanislav, Maurer, Gianna W, Hentze, Julie L, Rose, Morten, Werge, Thomas M, Rewitz, Kim
Published in PLoS genetics

An epigenetic clock for gestational age at birth based on blood methylation data

by Knight, Anna K, Craig, Jeffrey M, Theda, Christiane, Bækvad-Hansen, Marie, Bybjerg-Grauholm, Jonas, Hansen, Christine S, Hollegaard, Mads V, Hougaard, David M, Mortensen, Preben B, Weinsheimer, Shantel M, Werge, Thomas M, Brennan, Patricia A, Cubells, Joseph F, Newport, D Jeffrey, Stowe, Zachary N, Cheong, Jeanie L Y, Dalach, Philippa, Doyle, Lex W, Loke, Yuk J, Baccarelli, Andrea A, Just, Allan C, Wright, Robert O, Téllez-Rojo, Mara M, Svensson, Katherine, Trevisi, Letizia, Kennedy, Elizabeth M, Binder, Elisabeth B, Iurato, Stella, Czamara, Darina, Räikkönen, Katri, Lahti, Jari M T, Pesonen, Anu-Katriina, Kajantie, Eero, Villa, Pia M, Laivuori, Hannele, Hämäläinen, Esa, Park, Hea Jin, Bailey, Lynn B, Parets, Sasha E, Kilaru, Varun, Menon, Ramkumar, Horvath, Steve, Bush, Nicole R, LeWinn, Kaja Z, Tylavsky, Frances A, Conneely, Karen N, Smith, Alicia K
Published in Genome Biology

Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders

by Isles, Anthony R, Ingason, Andrés, Lowther, Chelsea, Walters, James, Gawlick, Micha, Stöber, Gerald, Rees, Elliott, Martin, Joanna, Little, Rosie B, Potter, Harry, Georgieva, Lyudmila, Pizzo, Lucilla, Ozaki, Norio, Aleksic, Branko, Kushima, Itaru, Ikeda, Masashi, Iwata, Nakao, Levinson, Douglas F, Gejman, Pablo V, Shi, Jianxin, Sanders, Alan R, Duan, Jubao, Willis, Joseph, Sisodiya, Sanjay, Costain, Gregory, Werge, Thomas M, Degenhardt, Franziska, Giegling, Ina, Rujescu, Dan, Hreidarsson, Stefan J, Saemundsen, Evald, Ahn, Joo Wook, Ogilvie, Caroline, Girirajan, Santhosh D, Stefansson, Hreinn, Stefansson, Kari, O'Donovan, Michael C, Owen, Michael J, Bassett, Anne, Kirov, George
Published in PLoS genetics

Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease

by Hagen, Christian M, Gonçalves, Vanessa F, Hedley, Paula L, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Hansen, Christine S, Kanters, Jørgen K, Nielsen, Jimmi, Mors, Ole, Demur, Alfonso B, Als, Thomas D, Nordentoft, Merete, Børglum, Anders, Mortensen, Preben B, Kennedy, James, Werge, Thomas M, Hougaard, David M, Christiansen, Michael
Published in PloS one

Transcriptomic networks implicate neuronal energetic abnormalities in three mouse models harboring autism and schizophrenia-associated mutations

by Gordon, Aaron, Forsingdal, Annika, Klewe, Ib Vestergaard, Nielsen, Jacob, Didriksen, Michael, Werge, Thomas, Geschwind, Daniel H
Published in Molecular psychiatry

Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: a study in male mice

by Didriksen, Michael, PhD, Fejgin, Kim, PhD, Birknow, Michelle R., MSc, Larsen, Peter H., PhD, Lauridsen, Jes B., PhD, Nielsen, Vibeke, BSc, Kallunki, Pekka, PhD, Christensen, Kenneth V., PhD, Stensbøl, Tine B., PhD, Egebjerg, Jan, PhD, Nielsen, Jacob, PhD, Nilsson, Simon R.O., PhD, Grayton, Hannah M., PhD, Gastambide, Francois, PhD, Celada, Pau, PhD, Artigas, Francesc, PhD, Santana, Noemi, PhD, Werge, Thomas M., PhD, Bastlund, Jesper F., PhD
Published in Journal of psychiatry & neuroscience

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder

by Walters, Raymond K., Lee, S. Hong, Brikell, Isabell, Ghirardi, Laura, Larsson, Henrik, Lichtenstein, Paul, Bell, Robert K., Bryc, Katarzyna, Fontanillas, Pierre, Hromatka, Bethann S., Huber, Karen E., Litterman, Nadia K., McIntyre, Matthew H., Mountain, Joanna L., Pitts, Steven J., Vacic, Vladimir, Anney, Richard J.L., Vasquez, Alejandro Arias, Arranz, Maria Jesús, Banaschewski, Tobias, Banaschewski, Tobias J., Mortensen, Preben Bo, Børglum, Anders, Charach, Alice, Crosbie, Jennifer, Dalsgaard, Soeren, Demontis, Ditte, Dempfle, Astrid, Elia, Josephine, Faraone, Stephen V., Franke, Barbara, Freitag, Christine, Gelernter, Joel, Grevet, Eugenio, Haavik, Jan, Hakonarson, Hakon, Hawi, Ziarih, Hinney, Anke, Holmans, Peter, Ickowitz, Abel, Kent, Lindsey, Kittel-Schneider, Sarah, Langley, Kate, Lesch, Klaus-Peter, Loo, Sandra K., Martin, Joanna, Medland, Sarah E., Mulas, Fernando, Mulligan, Aisling, O’Donovan, Michael C., Oades, Robert D., Palmason, Haukur, Rhode, Luis, Roeyers, Herbert, Romanos, Marcel, Romanos, Jasmin, Rothenberger, Aribert, Schäfer, Helmut, Scherag, André, Schimmelmann, Benno G., Sergeant, Joseph, Smalley, Susan L., Sonuga-Barke, Edmund J.S., Steinhausen, Hans-Christoph, Sullivan, Patrick F., Todorov, Alexandre, Waldman, Irwin, Wang, Yufeng, Warnke, Andreas, Williams, Nigel, Witt, Stephanie H., Yang, Li, Agerbo, Esben, Belliveau, Rich, Børglum, Anders D., Chambert, Kimberly, Dalsgaard, Søren, Dumont, Ashley, Goldstein, Jacqueline, Grove, Jakob, Howrigan, Daniel P., Huang, Hailiang, Martin, Alicia R., Mattheisen, Manuel, Moran, Jennifer, Mors, Ole, Pallesen, Jonatan, Poterba, Timothy, Poulsen, Jesper Buchhave, Robinson, Elise B., Satterstrom, F. Kyle, Stevens, Christine, Turley, Patrick, Pedersen, Marianne Giørtz, Mors, Ole, Nordentoft, Merete, Hougaard, David M., Bybjerg-Grauholm, Jonas, Franke, Barbara, Neale, Benjamin M.
Published in Biological psychiatry (1969)

Structural basis of organic cation transporter-3 inhibition

by Khanppnavar, Basavraj, Maier, Julian, Herborg, Freja, Gradisch, Ralph, Lazzarin, Erika, Luethi, Dino, Yang, Jae-Won, Qi, Chao, Holy, Marion, Jäntsch, Kathrin, Kudlacek, Oliver, Schicker, Klaus, Werge, Thomas, Gether, Ulrik, Stockner, Thomas, Korkhov, Volodymyr M, Sitte, Harald H
Published in Nature communications

Interactive effects between hemizygous 15q13.3 microdeletion and peripubertal stress on adult behavioral functions

by Giovanoli, Sandra, Werge, Thomas M, Mortensen, Preben B, Didriksen, Michael, Meyer, Urs
Published in Neuropsychopharmacology (New York, N.Y.)

Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes

by Bybjerg-Grauholm, Jonas, Hagen, Christian M, Gonçalves, Vanessa F, Bækvad-Hansen, Marie, Hansen, Christine S, Hedley, Paula L, Kanters, Jørgen K, Nielsen, Jimmi, Theisen, Michael, Mors, Ole, Kennedy, James, Als, Thomas D, Demur, Alfonso B, Nordentoft, Merete, Børglum, Anders, Mortensen, Preben B, Werge, Thomas M, Hougaard, David M, Christiansen, Michael
Published in PloS one

Using electronic patient records to discover disease correlations and stratify patient cohorts

by Roque, Francisco S, Jensen, Peter B, Schmock, Henriette, Dalgaard, Marlene, Andreatta, Massimo, Hansen, Thomas, Søeby, Karen, Bredkjær, Søren, Juul, Anders, Werge, Thomas, Jensen, Lars J, Brunak, Søren
Published in PLoS computational biology

The Complement Control-Related Genes CSMD1 and CSMD2 Associate to Schizophrenia

by Håvik, Bjarte, Le Hellard, Stephanie, Rietschel, Marcella, Lybæk, Helle, Djurovic, Srdjan, Mattheisen, Manuel, Mühleisen, Thomas W, Degenhardt, Franziska, Priebe, Lutz, Maier, Wolfgang, Breuer, Rene, Schulze, Thomas G, Agartz, Ingrid, Melle, Ingrid, Hansen, Thomas, Bramham, Clive R, Nöthen, Markus M, Stevens, Beth, Werge, Thomas, Andreassen, Ole A, Cichon, Sven, Steen, Vidar M
Published in Biological psychiatry (1969)

Human Disease Variation in the Light of Population Genomics

by Prohaska, Ana, Racimo, Fernando, Schork, Andrew J., Sikora, Martin, Stern, Aaron J., Ilardo, Melissa, Allentoft, Morten Erik, Folkersen, Lasse, Buil, Alfonso, Moreno-Mayar, J. Víctor, Korneliussen, Thorfinn, Geschwind, Daniel, Ingason, Andrés, Werge, Thomas, Nielsen, Rasmus, Willerslev, Eske
Published in Cell

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

by Joshi, Peter K, Pirastu, Nicola, Kentistou, Katherine A, Fischer, Krista, Hofer, Edith, Schraut, Katharina E, Clark, David W, Nutile, Teresa, Barnes, Catriona L K, Timmers, Paul R H J, Shen, Xia, Gandin, Ilaria, McDaid, Aaron F, Hansen, Thomas Folkmann, Gordon, Scott D, Giulianini, Franco, Boutin, Thibaud S, Abdellaoui, Abdel, Zhao, Wei, Medina-Gomez, Carolina, Bartz, Traci M, Lange, Leslie A, Raffield, Laura, Galesloot, Tessel E, Proitsi, Petroula, Yanek, Lisa R, Bielak, Lawrence F, Payton, Antony, Murgia, Federico, Concas, Maria Pina, Biino, Ginevra, Tajuddin, Salman M, Seppälä, Ilkka, Amin, Najaf, Boerwinkle, Eric, Børglum, Anders D, Campbell, Archie, Demerath, Ellen W, Demuth, Ilja, Ford, Ian, Gialluisi, Alessandro, Gögele, Martin, Graff, MariaElisa, Hingorani, Aroon, Hottenga, Jouke-Jan, Hougaard, David M, Ikram, M Arfan, Jylhä, Marja, Kuh, Diana, Ligthart, Lannie, Lill, Christina M, Lindenberger, Ulman, Lumley, Thomas, Mägi, Reedik, Marques-Vidal, Pedro, Medland, Sarah E, Nagy, Reka, Ollier, William E R, Peyser, Patricia A, Pramstaller, Peter P, Ridker, Paul M, Rivadeneira, Fernando, Ruggiero, Daniela, Saba, Yasaman, Schmidt, Reinhold, Slagboom, P Eline, Smith, Blair H, Sotoodehnia, Nona, van Rooij, Frank J A, Verbeek, André L, Vermeulen, Sita H, Vollenweider, Peter, Wang, Yunpeng, Werge, Thomas, Lehtimäki, Terho, Evans, Michele K, Pirastu, Mario, Fuchsberger, Christian, Bertram, Lars, Pendleton, Neil, Kardia, Sharon L R, Ciullo, Marina, Becker, Diane M, Wong, Andrew, Psaty, Bruce M, van Duijn, Cornelia M, Wilson, James G, Jukema, J Wouter, Kiemeney, Lambertus, Uitterlinden, André G, North, Kari E, Metspalu, Andres, Hayward, Caroline, Chasman, Daniel, Martin, Nicholas G, Sattar, Naveed, Campbell, Harry, Esko, Tōnu, Kutalik, Zoltán, Wilson, James F
Published in Nature communications

MicroRNAs show mutually exclusive expression patterns in the brain of adult male rats

by Olsen, Line, Klausen, Mikkel, Helboe, Lone, Nielsen, Finn Cilius, Werge, Thomas
Published in PloS one

Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate

by Andreassen, Ole A, Thompson, Wesley K, Schork, Andrew J, Ripke, Stephan, Mattingsdal, Morten, Kelsoe, John R, Kendler, Kenneth S, O'Donovan, Michael C, Rujescu, Dan, Werge, Thomas, Sklar, Pamela, Roddey, J Cooper, Chen, Chi-Hua, McEvoy, Linda, Desikan, Rahul S, Djurovic, Srdjan, Dale, Anders M
Published in PLoS genetics