Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and a Novel Class of Biomarkers for Heart Failure

by Meder, Benjamin, Haas, Jan, Sedaghat-Hamedani, Farbod, Kayvanpour, Elham, Frese, Karen, Lai, Alan, Nietsch, Rouven, Scheiner, Christina, Mester, Stefan, Bordalo, Diana Martins, Amr, Ali, Dietrich, Carsten, Pils, Dietmar, Siede, Dominik, Hund, Hauke, Bauer, Andrea, Holzer, Daniel Benjamin, Ruhparwar, Arjang, Mueller-Hennessen, Matthias, Weichenhan, Dieter, Plass, Christoph, Weis, Tanja, Backs, Johannes, Wuerstle, Maximilian, Keller, Andreas, Katus, Hugo A, Posch, Andreas E
Published in Circulation (New York, N.Y.)

A new metabolomic signature in type-2 diabetes mellitus and its pathophysiology

by Padberg, Inken, Peter, Erik, González-Maldonado, Sandra, Witt, Henning, Mueller, Matthias, Weis, Tanja, Bethan, Bianca, Liebenberg, Volker, Wiemer, Jan, Katus, Hugo A, Rein, Dietrich, Schatz, Philipp
Published in PloS one

Epigenetic regulation of cardiac electrophysiology in atrial fibrillation: HDAC2 determines action potential duration and suppresses NRSF in cardiomyocytes

by Lugenbiel, Patrick, Govorov, Katharina, Syren, Pascal, Rahm, Ann-Kathrin, Wieder, Teresa, Wunsch, Maximilian, Weiberg, Nadine, Manolova, Emili, Gramlich, Dominik, Rivinius, Rasmus, Finke, Daniel, Lehmann, Lorenz H., Schweizer, Patrick A., Frank, Derk, El Tahry, Fadwa A., Bruehl, Claus, Heimberger, Tanja, Sandke, Steffi, Weis, Tanja, Most, Patrick, Schmack, Bastian, Ruhparwar, Arjang, Karck, Matthias, Frey, Norbert, Katus, Hugo A., Thomas, Dierk
Published in Basic research in cardiology

Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure

by Müller, Oliver J, Heckmann, Markus B, Ding, Lin, Rapti, Kleopatra, Rangrez, Ashraf Y, Gerken, Thomas, Christiansen, Nicole, Rennefahrt, Ulrike E E, Witt, Henning, González Maldonado, Sandra, Ternes, Philipp, Schwab, Dominic M, Ruf, Theresa, Hille, Susanne, Remes, Anca, Jungmann, Andreas, Weis, Tanja M, Kreußer, Julia S, Gröne, Hermann-Josef, Backs, Johannes, Schatz, Philipp, Katus, Hugo A, Frey, Norbert
Published in Cardiovascular research

Energy Metabolites as Biomarkers in Ischemic and Dilated Cardiomyopathy

by Haas, Jan, Frese, Karen S, Sedaghat-Hamedani, Farbod, Kayvanpour, Elham, Tappu, Rewati, Nietsch, Rouven, Tugrul, Oguz Firat, Wisdom, Michael, Dietrich, Carsten, Amr, Ali, Weis, Tanja, Niederdränk, Torsten, Murphy, Michael P, Krieg, Thomas, Dörr, Marcus, Völker, Uwe, Fielitz, Jens, Frey, Norbert, Felix, Stephan B, Keller, Andreas, Katus, Hugo A, Meder, Benjamin
Published in International journal of molecular sciences

Relevance of pre-analytical blood management on the emerging cardiovascular protein biomarkers TWEAK and HMGB1 and on miRNA serum and plasma profiling

by Basso, Daniela, Padoan, Andrea, Laufer, Thomas, Aneloni, Vittorio, Moz, Stefania, Schroers, Hannah, Pelloso, Michela, Saiz, Anna, Krapp, Medea, Fogar, Paola, Cornoldi, Paola, Zambon, Carlo-Federico, Rossi, Elisa, La Malfa, Marco, Marotti, Alberto, Brefort, Thomas, Weis, Tanja M., Katus, Hugo A., Plebani, Mario
Published in Clinical biochemistry

Genomic structural variations lead to dysregulation of important coding and non‐coding RNA species in dilated cardiomyopathy

by Haas, Jan, Mester, Stefan, Lai, Alan, Frese, Karen S, Sedaghat‐Hamedani, Farbod, Kayvanpour, Elham, Rausch, Tobias, Nietsch, Rouven, Boeckel, Jes‐Niels, Carstensen, Avisha, Völkers, Mirko, Dietrich, Carsten, Pils, Dietmar, Amr, Ali, Holzer, Daniel B, Martins Bordalo, Diana, Oehler, Daniel, Weis, Tanja, Mereles, Derliz, Buss, Sebastian, Riechert, Eva, Wirsz, Emil, Wuerstle, Maximilian, Korbel, Jan O, Keller, Andreas, Katus, Hugo A, Posch, Andreas E, Meder, Benjamin
Published in EMBO molecular medicine

Stranded on an island: consequences of forest fragmentation for body size variations in an arboreal mammal, the edible dormouse (Glis glis)

by Fietz, Joanna, Weis-Dootz, Tanja
Published in Population ecology

Differential regulation of KCa2.1 (KCNN1) K+ channel expression by histone deacetylases in atrial fibrillation with concomitant heart failure

by Rahm, Ann‐Kathrin, Wieder, Teresa, Gramlich, Dominik, Müller, Mara Elena, Wunsch, Maximilian N., El Tahry, Fadwa A., Heimberger, Tanja, Sandke, Steffi, Weis, Tanja, Most, Patrick, Katus, Hugo A., Thomas, Dierk, Lugenbiel, Patrick
Published in Physiological reports

Genetic consequences of forest fragmentation for a highly specialized arboreal mammal--the edible dormouse

by Fietz, Joanna, Tomiuk, Jürgen, Loeschcke, Volker, Weis-Dootz, Tanja, Segelbacher, Gernot
Published in PloS one

Marathon-Induced Cardiac Strain as Model for the Evaluation of Diagnostic microRNAs for Acute Myocardial Infarction

by Shirvani Samani, Omid, Scherr, Johannes, Kayvanpour, Elham, Haas, Jan, Lehmann, David H, Gi, Weng-Tein, Frese, Karen S, Nietsch, Rouven, Fehlmann, Tobias, Sandke, Steffi, Weis, Tanja, Keller, Andreas, Katus, Hugo A, Halle, Martin, Frey, Norbert, Meder, Benjamin, Sedaghat-Hamedani, Farbod
Published in Journal of clinical medicine

Atlas of the clinical genetics of human dilated cardiomyopathy

by Haas, Jan, Frese, Karen S, Peil, Barbara, Kloos, Wanda, Keller, Andreas, Nietsch, Rouven, Feng, Zhu, Müller, Sabine, Kayvanpour, Elham, Vogel, Britta, Sedaghat-Hamedani, Farbod, Lim, Wei-Keat, Zhao, Xiaohong, Fradkin, Dmitriy, Köhler, Doreen, Fischer, Simon, Franke, Jennifer, Marquart, Sabine, Barb, Ioana, Li, Daniel Tian, Amr, Ali, Ehlermann, Philipp, Mereles, Derliz, Weis, Tanja, Hassel, Sarah, Kremer, Andreas, King, Vanessa, Wirsz, Emil, Isnard, Richard, Komajda, Michel, Serio, Alessandra, Grasso, Maurizia, Syrris, Petros, Wicks, Eleanor, Plagnol, Vincent, Lopes, Luis, Gadgaard, Tenna, Eiskjær, Hans, Jørgensen, Mads, Garcia-Giustiniani, Diego, Ortiz-Genga, Martin, Crespo-Leiro, Maria G, Deprez, Rondal H Lekanne Dit, Christiaans, Imke, van Rijsingen, Ingrid A, Wilde, Arthur A, Waldenstrom, Anders, Bolognesi, Martino, Bellazzi, Riccardo, Mörner, Stellan, Bermejo, Justo Lorenzo, Monserrat, Lorenzo, Villard, Eric, Mogensen, Jens, Pinto, Yigal M, Charron, Philippe, Elliott, Perry, Arbustini, Eloisa, Katus, Hugo A, Meder, Benjamin
Published in European heart journal

Inhibition of cardiac K v 4.3 (I to ) channel isoforms by class I antiarrhythmic drugs lidocaine and mexiletine

by Rahm, Ann-Kathrin, Müller, Mara Elena, Gramlich, Dominik, Lugenbiel, Patrick, Uludag, Ecem, Rivinius, Rasmus, Ullrich, Nina D, Schmack, Bastian, Ruhparwar, Arjang, Heimberger, Tanja, Weis, Tanja, Karck, Matthias, Katus, Hugo A, Thomas, Dierk
Published in European journal of pharmacology

Inhibition of cardiac Kv4.3 (Ito) channel isoforms by class I antiarrhythmic drugs lidocaine and mexiletine

by Rahm, Ann-Kathrin, Müller, Mara Elena, Gramlich, Dominik, Lugenbiel, Patrick, Uludag, Ecem, Rivinius, Rasmus, Ullrich, Nina D., Schmack, Bastian, Ruhparwar, Arjang, Heimberger, Tanja, Weis, Tanja, Karck, Matthias, Katus, Hugo A., Thomas, Dierk
Published in European journal of pharmacology

HDAC2-dependent remodeling of KCa2.2 (KCNN2) and KCa2.3 (KCNN3) K+ channels in atrial fibrillation with concomitant heart failure

by Rahm, Ann-Kathrin, Wieder, Teresa, Gramlich, Dominik, Müller, Mara Elena, Wunsch, Maximilian N., El Tahry, Fadwa A., Heimberger, Tanja, Weis, Tanja, Most, Patrick, Katus, Hugo A., Thomas, Dierk, Lugenbiel, Patrick
Published in Life sciences (1973)

Indirect epigenetic testing identifies a diagnostic signature of cardiomyocyte DNA methylation in heart failure

by Oeing, Christian U., Pepin, Mark E., Saul, Kerstin B., Agircan, Ayça Seyhan, Assenov, Yassen, Merkel, Tobias S., Sedaghat-Hamedani, Farbod, Weis, Tanja, Meder, Benjamin, Guan, Kaomei, Plass, Christoph, Weichenhan, Dieter, Siede, Dominik, Backs, Johannes
Published in Basic research in cardiology

A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy

by Meder, Benjamin, Rühle, Frank, Weis, Tanja, Homuth, Georg, Keller, Andreas, Franke, Jennifer, Peil, Barbara, Lorenzo Bermejo, Justo, Frese, Karen, Huge, Andreas, Witten, Anika, Vogel, Britta, Haas, Jan, Völker, Uwe, Ernst, Florian, Teumer, Alexander, Ehlermann, Philipp, Zugck, Christian, Friedrichs, Frauke, Kroemer, Heyo, Dörr, Marcus, Hoffmann, Wolfgang, Maisch, Bernhard, Pankuweit, Sabine, Ruppert, Volker, Scheffold, Thomas, Kühl, Uwe, Schultheiss, Hans-Peter, Kreutz, Reinhold, Ertl, Georg, Angermann, Christiane, Charron, Philippe, Villard, Eric, Gary, Françoise, Isnard, Richard, Komajda, Michel, Lutz, Matthias, Meitinger, Thomas, Sinner, Moritz F, Wichmann, H.-Erich, Krawczak, Michael, Ivandic, Boris, Weichenhan, Dieter, Gelbrich, Goetz, El-Mokhtari, Nour-Eddine, Schreiber, Stefan, Felix, Stephan B, Hasenfuß, Gerd, Pfeufer, Arne, Hübner, Norbert, Kääb, Stefan, Arbustini, Eloisa, Rottbauer, Wolfgang, Frey, Norbert, Stoll, Monika, Katus, Hugo A
Published in European heart journal

microRNA neural networks improve diagnosis of acute coronary syndrome (ACS)

by Kayvanpour, Elham, Gi, Weng-Tein, Sedaghat-Hamedani, Farbod, Lehmann, David H., Frese, Karen S., Haas, Jan, Tappu, Rewati, Samani, Omid Shirvani, Nietsch, Rouven, Kahraman, Mustafa, Fehlmann, Tobias, Müller-Hennessen, Matthias, Weis, Tanja, Giannitsis, Evangelos, Niederdränk, Torsten, Keller, Andreas, Katus, Hugo A., Meder, Benjamin
Published in Journal of molecular and cellular cardiology

Thermal exchange bias field drift in field cooled Mn83Ir17/Co70Fe30 thin films after 10 keV He ion bombardment

by Ehresmann, Arno, Schmidt, Christoph, Weis, Tanja, Engel, Dieter
Published in Journal of applied physics

The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies

by Hoffmann, Julia, Hanß, Sabine, Kraus, Monika, Schaller, Jens, Schäfer, Christian, Stahl, Dana, Anker, Stefan D., Anton, Gabriele, Bahls, Thomas, Blankenberg, Stefan, Blumentritt, Arne, Boldt, Leif-Hendrik, Cordes, Steffen, Desch, Steffen, Doehner, Wolfram, Dörr, Marcus, Edelmann, Frank, Eitel, Ingo, Endres, Matthias, Engelhardt, Stefan, Erdmann, Jeanette, Eulenburg, Katharina, Falk, Volkmar, Felix, Stephan B., Frank, Derk, Franke, Thomas, Frey, Norbert, Friede, Tim, Geidel, Lars, Germans, Lisa, Grabmaier, Ulrich, Halle, Martin, Hausleiter, Jörg, Jakobi, Vera, Jebran, Ahmad-Fawad, Jobs, Alexander, Kääb, Stefan, Karakas, Mahir, Katus, Hugo A., Klatt, Alexandra, Knosalla, Christoph, Krebser, Joachim, Landmesser, Ulf, Lee, Mahsa, Lehnert, Kristin, Lesser, Stephanie, Leyh, Katrin, Lorbeer, Roberto, Mach-Kolb, Stephanie, Meder, Benjamin, Nagel, Eike, Nolte, Christian H., Parwani, Abdul S., Petersmann, Astrid, Puls, Miriam, Rau, Henriette, Reiser, Maximilian, Rienhoff, Otto, Scharfe, Tabea, Schattschneider, Mario, Scheel, Heiko, Schnabel, Renate B., Schuster, Andreas, Schmitt, Boris, Seidler, Tim, Seiffert, Moritz, Stähli, Barbara-Elisabeth, Stas, Adriane, J. Stocker, Thomas, von Stülpnagel, Lukas, Thiele, Holger, Wachter, Rolf, Wakili, Reza, Weis, Tanja, Weitmann, Kerstin, Wichmann, Heinz-Erich, Wild, Philipp, Zeller, Tanja, Hoffmann, Wolfgang, Zeisberg, Elisabeth Maria, Zimmermann, Wolfram-Hubertus, Krefting, Dagmar, Kühne, Titus, Peters, Annette, Hasenfuß, Gerd, Massberg, Steffen, Sommer, Thomas, Dimmeler, Stefanie, Eschenhagen, Thomas, Nauck, Matthias
Published in Clinical research in cardiology