A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules by Patel-Murray, Natasha L, Adam, Miriam, Huynh, Nhan, Wassie, Brook T, Milani, Pamela, Fraenkel, Ernest

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Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements by Pirhaji, Leila, Milani, Pamela, Dalin, Simona, Wassie, Brook T, Dunn, Denise E, Fenster, Robert J, Avila-Pacheco, Julian, Greengard, Paul, Clish, Clary B, Heiman, Myriam, Lo, Donald C, Fraenkel, Ernest

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Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation by Smith-Geater, Charlene, Hernandez, Sarah J., Lim, Ryan G., Adam, Miriam, Wu, Jie, Stocksdale, Jennifer T., Wassie, Brook T., Gold, Maxwell Philip, Wang, Keona Q., Miramontes, Ricardo, Kopan, Lexi, Orellana, Iliana, Joy, Shona, Kemp, Paul J., Allen, Nicholas D., Fraenkel, Ernest, Thompson, Leslie M.

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Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines by Baxi, Emily G, Thompson, Terri, Li, Jonathan, Kaye, Julia A, Lim, Ryan G, Wu, Jie, Ramamoorthy, Divya, Lima, Leandro, Vaibhav, Vineet, Matlock, Andrea, Frank, Aaron, Coyne, Alyssa N, Landin, Barry, Ornelas, Loren, Mosmiller, Elizabeth, Thrower, Sara, Farr, S Michelle, Panther, Lindsey, Gomez, Emilda, Galvez, Erick, Perez, Daniel, Meepe, Imara, Lei, Susan, Mandefro, Berhan, Trost, Hannah, Pinedo, Louis, Banuelos, Maria G, Liu, Chunyan, Moran, Ruby, Garcia, Veronica, Workman, Michael, Ho, Richie, Wyman, Stacia, Roggenbuck, Jennifer, Harms, Matthew B, Stocksdale, Jennifer, Miramontes, Ricardo, Wang, Keona, Venkatraman, Vidya, Holewenski, Ronald, Sundararaman, Niveda, Pandey, Rakhi, Manalo, Danica-Mae, Donde, Aneesh, Huynh, Nhan, Adam, Miriam, Wassie, Brook T, Vertudes, Edward, Amirani, Naufa, Raja, Krishna, Thomas, Reuben, Hayes, Lindsey, Lenail, Alex, Cerezo, Aianna, Luppino, Sarah, Farrar, Alanna, Pothier, Lindsay, Prina, Carolyn, Morgan, Todd, Jamil, Arish, Heintzman, Sarah, Jockel-Balsarotti, Jennifer, Karanja, Elizabeth, Markway, Jesse, McCallum, Molly, Joslin, Ben, Alibazoglu, Deniz, Kolb, Stephen, Ajroud-Driss, Senda, Baloh, Robert, Heitzman, Daragh, Miller, Tim, Glass, Jonathan D, Patel-Murray, Natasha Leanna, Yu, Hong, Sinani, Ervin, Vigneswaran, Prasha, Sherman, Alexander V, Ahmad, Omar, Roy, Promit, Beavers, Jay C, Zeiler, Steven, Krakauer, John W, Agurto, Carla, Cecchi, Guillermo, Raghav, Yogindra, Sachs, Karen, Ehrenberger, Tobias, Bruce, Elizabeth, Cudkowicz, Merit E, Maragakis, Nicholas, Norel, Raquel, Van Eyk, Jennifer E, Finkbeiner, Steven, Berry, James, Sareen, Dhruv, Thompson, Leslie M, Fraenkel, Ernest, Svendsen, Clive N, Rothstein, Jeffrey D

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A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses by Gross, Sean M, Dane, Mark A, Smith, Rebecca L, Devlin, Kaylyn L, McLean, Ian C, Derrick, Daniel S, Mills, Caitlin E, Subramanian, Kartik, London, Alexandra B, Torre, Denis, Evangelista, John Erol, Clarke, Daniel J B, Xie, Zhuorui, Erdem, Cemal, Lyons, Nicholas, Natoli, Ted, Pessa, Sarah, Lu, Xiaodong, Mullahoo, James, Li, Jonathan, Adam, Miriam, Wassie, Brook, Liu, Moqing, Kilburn, David F, Liby, Tiera A, Bucher, Elmar, Sanchez-Aguila, Crystal, Daily, Kenneth, Omberg, Larsson, Wang, Yunguan, Jacobson, Connor, Yapp, Clarence, Chung, Mirra, Vidovic, Dusica, Lu, Yiling, Schurer, Stephan, Lee, Albert, Pillai, Ajay, Subramanian, Aravind, Papanastasiou, Malvina, Fraenkel, Ernest, Feiler, Heidi S, Mills, Gordon B, Jaffe, Jake D, Ma'ayan, Avi, Birtwistle, Marc R, Sorger, Peter K, Korkola, James E, Gray, Joe W, Heiser, Laura M

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An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients by Phatnani, Hemali, Kwan, Justin, Sareen, Dhruv, Broach, James R., Simmons, Zachary, Arcila-Londono, Ximena, Lee, Edward B., Van Deerlin, Vivianna M., Shneider, Neil A., Fraenkel, Ernest, Ostrow, Lyle W., Baas, Frank, Zaitlen, Noah, Malaspina, Andrea, Fratta, Pietro, Cox, Gregory A., Thompson, Leslie M., Finkbeiner, Steve, Dardiotis, Efthimios, Chandran, Siddharthan, Pal, Suvankar, Hornstein, Eran, MacGowan, Daniel J., Heiman-Patterson, Terry, Hammell, Molly G., Patsopoulos, Nikolaos.A., Butovsky, Oleg, Dubnau, Joshua, Nath, Avindra, Bowser, Robert, Harms, Matt, Poss, Mary, Phillips-Cremins, Jennifer, Crary, John, Atassi, Nazem, Lange, Dale J., Adams, Darius J., Stefanis, Leonidas, Gotkine, Marc, Baloh, Robert H., Babu, Suma, Raj, Towfique, Paganoni, Sabrina, Shalem, Ophir, Smith, Colin, Zhang, Bin, Harris, Brent, Broce, Iris, Drory, Vivian, Ravits, John, McMillan, Corey, Menon, Vilas, Wu, Lani, Altschuler, Steven, Li, Jonathan, Lim, Ryan G., Kaye, Julia A., Dardov, Victoria, Coyne, Alyssa N., Wu, Jie, Milani, Pamela, Cheng, Andrew, Thompson, Terri G., Ornelas, Loren, Frank, Aaron, Adam, Miriam, Banuelos, Maria G., Casale, Malcolm, Cox, Veerle, Escalante-Chong, Renan, Daigle, J. Gavin, Gomez, Emilda, Hayes, Lindsey, Holewenski, Ronald, Lei, Susan, Lenail, Alex, Lima, Leandro, Mandefro, Berhan, Matlock, Andrea, Panther, Lindsay, Patel-Murray, Natasha Leanna, Pham, Jacqueline, Ramamoorthy, Divya, Sachs, Karen, Shelley, Brandon, Stocksdale, Jennifer, Trost, Hannah, Wilhelm, Mark, Venkatraman, Vidya, Wassie, Brook T., Wyman, Stacia, Yang, Stephanie, Van Eyk, Jennifer E., Lloyd, Thomas E., Finkbeiner, Steven, Fraenkel, Ernest, Rothstein, Jeffrey D., Sareen, Dhruv, Svendsen, Clive N., Thompson, Leslie M.

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QTY code enables design of detergent-free chemokine receptors that retain ligand-binding activities by Zhang, Shuguang, Tao, Fei, Qing, Rui, Tang, Hongzhi, Skuhersky, Michael, Corin, Karolina, Tegler, Lotta, Wassie, Asmamaw, Wassie, Brook, Kwon, Yongwon, Suter, Bernhard, Entzian, Clemens, Schubert, Thomas, Yang, Ge, Labahn, Jörg, Kubicek, Jan, Maertens, Barbara

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Treatment with JQ1, a BET bromodomain inhibitor, is selectively detrimental to R6/2 Huntington’s disease mice by Kedaigle, Amanda J, Reidling, Jack C, Lim, Ryan G, Adam, Miriam, Wu, Jie, Wassie, Brook, Stocksdale, Jennifer T, Casale, Malcolm S, Fraenkel, Ernest, Thompson, Leslie M

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Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controls by Tsitkov, Stanislav, Valentine, Kelsey, Kozareva, Velina, Donde, Aneesh, Frank, Aaron, Lei, Susan, E Van Eyk, Jennifer, Finkbeiner, Steve, Rothstein, Jeffrey D, Thompson, Leslie M, Sareen, Dhruv, Svendsen, Clive N, Fraenkel, Ernest

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NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency by Matlock, Andrea D, Vaibhav, Vineet, Holewinski, Ronald, Venkatraman, Vidya, Dardov, Victoria, Manalo, Danica-Mae, Shelley, Brandon, Ornelas, Loren, Banuelos, Maria, Mandefro, Berhan, Escalante-Chong, Renan, Li, Jonathan, Finkbeiner, Steve, Fraenkel, Ernest, Rothstein, Jeffrey, Thompson, Leslie, Sareen, Dhruv, Svendsen, Clive N, Van Eyk, Jennifer E

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