Improving reporting standards for polygenic scores in risk prediction studies

by Wand, Hannah, Lambert, Samuel A, Tamburro, Cecelia, Iacocca, Michael A, O'Sullivan, Jack W, Sillari, Catherine, Kullo, Iftikhar J, Rowley, Robb, Dron, Jacqueline S, Brockman, Deanna, Venner, Eric, McCarthy, Mark I, Antoniou, Antonis C, Easton, Douglas F, Hegele, Robert A, Khera, Amit V, Chatterjee, Nilanjan, Kooperberg, Charles, Edwards, Karen, Vlessis, Katherine, Kinnear, Kim, Danesh, John N, Parkinson, Helen, Ramos, Erin M, Roberts, Megan C, Ormond, Kelly E, Khoury, Muin J, Janssens, A Cecile J W, Goddard, Katrina A B, Kraft, Peter, MacArthur, Jaqueline A L, Inouye, Michael, Wojcik, Genevieve L
Published in Nature (London)

The Clinical Genome Resource (ClinGen) Familial Hypercholesterolemia Variant Curation Expert Panel consensus guidelines for LDLR variant classification

by Chora, Joana R., Iacocca, Michael A., Tichý, Lukáš, Wand, Hannah, Kurtz, C. Lisa, Zimmermann, Heather, Leon, Annette, Williams, Maggie, Humphries, Steve E., Hooper, Amanda J., Trinder, Mark, Brunham, Liam R., Costa Pereira, Alexandre, Jannes, Cinthia E., Chen, Margaret, Chonis, Jessica, Wang, Jian, Kim, Serra, Johnston, Tami, Soucek, Premysl, Kramarek, Michal, Leigh, Sarah E., Carrié, Alain, Sijbrands, Eric J., Hegele, Robert A., Freiberger, Tomáš, Knowles, Joshua W., Bourbon, Mafalda
Published in Genetics in medicine

Gene therapy as a potential therapeutic option for Duchenne muscular dystrophy: A qualitative preference study of patients and parents

by Landrum Peay, Holly, Fischer, Ryan, Tzeng, Janice P, Hesterlee, Sharon E, Morris, Carl, Strong Martin, Amy, Rensch, Colin, Smith, Edward, Ricotti, Valeria, Beaverson, Katherine, Wand, Hannah, Mansfield, Carol
Published in PloS one

Proteomic Analysis of Sera from Individuals with Diffuse Cutaneous Systemic Sclerosis Reveals a Multianalyte Signature Associated with Clinical Improvement during Imatinib Mesylate...

by Haddon, D James, Wand, Hannah E, Jarrell, Justin A, Spiera, Robert F, Utz, Paul J, Gordon, Jessica K, Chung, Lorinda S
Published in Journal of rheumatology

ClinGen Variant Curation Interface: a variant classification platform for the application of evidence criteria from ACMG/AMP guidelines

by Preston, Christine G, Wright, Matt W, Madhavrao, Rao, Harrison, Steven M, Goldstein, Jennifer L, Luo, Xi, Wand, Hannah, Wulf, Bryan, Cheung, Gloria, Mandell, Mark E, Tong, Howard, Cheng, Shaung, Iacocca, Michael A, Pineda, Arturo Lopez, Popejoy, Alice B, Dalton, Karen, Zhen, Jimmy, Dwight, Selina S, Babb, Lawrence, DiStefano, Marina, O'Daniel, Julianne M, Lee, Kristy, Riggs, Erin R, Zastrow, Diane B, Mester, Jessica L, Ritter, Deborah I, Patel, Ronak Y, Subramanian, Sai Lakshmi, Milosavljevic, Aleksander, Berg, Jonathan S, Rehm, Heidi L, Plon, Sharon E, Cherry, J Michael, Bustamante, Carlos D, Costa, Helio A
Published in Genome medicine

Multiplex giant magnetoresistive biosensor microarrays identify interferon-associated autoantibodies in systemic lupus erythematosus

by Lee, Jung-Rok, Haddon, D James, Wand, Hannah E, Price, Jordan V, Diep, Vivian K, Hall, Drew A, Petri, Michelle, Baechler, Emily C, Balboni, Imelda M, Utz, Paul J, Wang, Shan X
Published in Scientific reports

Re-envisioning community genetics: community empowerment in preventive genomics

by Wand, Hannah, Martschenko, Daphne O., Smitherman, Annamaria, Michelson, Sheryl, Pun, Ting, Witte, John S., Scott, Stuart A., Cho, Mildred K., Ashley, Euan A.
Published in Journal of community genetics

P833: A novel cardiac genetic knowledge scale: Development and evaluation of face validity and concept validity

by Christian, Susan, Baker, Amy, Dzwiniel, Tara, Borle, Kennedy, Mostafavi, Roya, Wand, Hannah, Slamon, Jill, Biesecker, Barbara, Yeates, Laura
Published in Genetics in Medicine Open

Application of a framework to guide genetic testing communication across clinical indications

by Hallquist, Miranda L G, Tricou, Eric P, Ormond, Kelly E, Savatt, Juliann M, Coughlin, 2nd, Curtis R, Faucett, W Andrew, Hercher, Laura, Levy, Howard P, O'Daniel, Julianne M, Peay, Holly L, Stosic, Melissa, Smith, Maureen, Uhlmann, Wendy R, Wand, Hannah, Wain, Karen E, Buchanan, Adam H
Published in Genome medicine

Differential locus expansion distinguishes Toxoplasmatinae species and closely related strains of Toxoplasma gondii

by Adomako-Ankomah, Yaw, Wier, Gregory M, Borges, Adair L, Wand, Hannah E, Boyle, Jon P
Published in mBio

Abstract 17417: Pathogenic and Likely Pathogenic Missense Variants in Cardiovascular Disease Genes Cluster Around Functional Domains

by Ten, Nicholas S, Grove, Megan, Wand, Hannah, Ison, Hannah, Pariani, Mitchel, Wheeler, Matthew T, Ashley, Euan A, Parikh, Victoria N
Published in Circulation (New York, N.Y.)

Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries

by Weale, Michael E., Riveros-Mckay, Fernando, Selzam, Saskia, Seth, Priyanka, Moore, Rachel, Tarran, William A., Gradovich, Eva, Giner-Delgado, Carla, Palmer, Duncan, Wells, Daniel, Saffari, Ayden, Sivley, R. Michael, Lachapelle, Alexander S., Wand, Hannah, Clarke, Shoa L., Knowles, Joshua W., O'Sullivan, Jack W., Ashley, Euan A., McVean, Gil, Plagnol, Vincent, Donnelly, Peter
Published in The American journal of cardiology

Clinical Genetics Lacks Standard Definitions and Protocols for the Collection and Use of Diversity Measures

by Popejoy, Alice B., Crooks, Kristy R., Fullerton, Stephanie M., Hindorff, Lucia A., Hooker, Gillian W., Koenig, Barbara A., Pino, Natalie, Ramos, Erin M., Ritter, Deborah I., Wand, Hannah, Wright, Matt W., Yudell, Michael, Zou, James Y., Plon, Sharon E., Bustamante, Carlos D., Ormond, Kelly E.
Published in American journal of human genetics

Abstract 13771: Combining Clinical and Polygenic Risk Improves Stroke Prediction Among Individuals With Atrial Fibrillation

by Osullivan, Jack W, Shcherbina, Anna, Justesen, Johanne M, Turakhia, Mintu, Perez, Marco V, Wand, Hannah, Tcheandjieu, Catherine, Clarke, Shoa L, Harrington, Robert A, Rivas, Manuel A, Ashley, Euan A
Published in Circulation (New York, N.Y.)

Finding missed cases of familial hypercholesterolemia in health systems using machine learning

by Banda, Juan M, Sarraju, Ashish, Abbasi, Fahim, Parizo, Justin, Pariani, Mitchel, Ison, Hannah, Briskin, Elinor, Wand, Hannah, Dubois, Sebastien, Jung, Kenneth, Myers, Seth A, Rader, Daniel J, Leader, Joseph B, Murray, Michael F, Myers, Kelly D, Wilemon, Katherine, Shah, Nigam H, Knowles, Joshua W
Published in NPJ digital medicine

Differential Locus Expansion Distinguishes italic toggle="yes">Toxoplasmatinae /italic> Species and Closely Related Strains of Toxoplasma gondii

by Yaw Adomako-Ankomah, Gregory M. Wier, Adair L. Borges, Hannah E. Wand, Jon P. Boyle
Published in mBio

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

by Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Hill, Helen, Lazarus, Rajeka, Lawrie, Alison M, McGregor, Alastair, Villafana, Tonya L, Gilbert, Sarah C, Aban, Marites, Aboagye, Jeremy, Adam, Matthew, Adams, Kirsty, Alves, Mariana P.S., Barnes, Eleanor, Berrie, Eleanor, Bewley, Kevin R., Bletchly, Heather, Borthwick, Nicola, Brown, Phillip, Buttigieg, Karen R., Cashen, Paul, Castro, Lucia Carratala, Chadwick, Jim, Chapman, David, Charlton, Sue, Clark, Matthew, Clutterbuck, Elizabeth A., Cooper, Cushla, Cooper, Rachel, Darroch, Paula, Dearlove, David, Drake-Brockman, Rachael, van Eck, Samual, Farrar, Madi, Fraiman, Pedro H.A., Gracie, Lara, Grossi, Leonardo, Hanrath, Aidan T., Harris, Tara, Hassan, Shadin, Hay, Jodie, Head, Ian, Hodges, Gina, Horne, Elizea, Hou, Mimi M., Humphries, Holly E., Hyder-Wright, Angela, Jeffers, Helen, Karampatsas, Konstantinos, Keen, Jade, Khan, Liaquat, King, Thomas B., Klenerman, Paul, Lees, Emily A., Li, Yuanyuan, Loew, Lisa, Marques, Gabriela N., Masilela, Mduduzi, Mathew, Moncy, Meijs, Wilma, Morris, Susan, Mpelembue, Mushiya, Noal, Helena, Nugent, Fay L., O'Connor, Daniel, Olchawski, Victoria, O'Reilly, Paula, Phillips, Daniel J., Pickup, Lorinda, Du Plessis, Joan, Pollard, Samuel, Poulton, Ian, Pulido, David, Reiné, Jesús, Resuello-Dauti, Mila, Richter, Alex, Roche, Sophie, Rollier, Christine, Ruiz, Sarah, Sala, Claudia, Sanchez-Gonzalez, Amada, Sharpe, Hannah E., Smith, Daniel C., Smith, Holly E., Soares, Tiago, Souza, Cinthia M.C.D.L., Spina, Fernanda, Steven, Jill, Stockdale, Lisa, Stockwell, Lisa V., Sturdy, Ann, Tarr, Alexander W., Taylor, Ursula, Themistocleous, Andreas, Tsheko, Betty Lebogang, Turabi, Aadil, Waddington, Claire S., Wallis, Erica, Webb, Stewart
Published in The Lancet (British edition)

Characterization of pre-antibiotic era Klebsiella pneumoniae isolates with respect to antibiotic/disinfectant susceptibility and virulence in Galleria mellonella

by Wand, Matthew E, Baker, Kate S, Benthall, Gabriel, McGregor, Hannah, McCowen, James W I, Deheer-Graham, Ana, Sutton, J Mark
Published in Antimicrobial agents and chemotherapy

The Prevalence and Clinical Relevance of ASA Nonresponse After Cardiac Surgery: A Prospective Bicentric Study

by Wand, Saskia, Adam, Elisabeth Hannah, Wetz, Anna Julienne, Meybohm, Patrick, Kunze-Szikszay, Nils, Zacharowski, Kai, Popov, Aron Frederick, Moritz, Anton, Moldenhauer, Lisa, Kaiser, Julia, Bauer, Martin, Weber, Christian Friedrich
Published in Clinical and applied thrombosis/hemostasis

ChAdOx1 nCoV-19 protection against SARS-CoV-2 in rhesus macaque and ferret challenge models

by Lambe, Teresa, Spencer, Alexandra J, Thomas, Kelly M, Gooch, Karen E, Thomas, Stephen, White, Andrew D, Humphries, Holly E, Wright, Daniel, Belij-Rammerstorfer, Sandra, Thakur, Nazia, Conceicao, Carina, Watson, Robert, Alden, Leonie, Allen, Lauren, Aram, Marilyn, Bewley, Kevin R, Brunt, Emily, Brown, Phillip, Cavell, Breeze E, Cobb, Rebecca, Fotheringham, Susan A, Gilbride, Ciaran, Harris, Debbie J, Ho, Catherine M K, Hunter, Laura, Kennard, Chelsea L, Leung, Stephanie, Lucas, Vanessa, Ngabo, Didier, Ryan, Kathryn A, Sharpe, Hannah, Sarfas, Charlotte, Sibley, Laura, Slack, Gillian S, Ulaszewska, Marta, Wand, Nadina, Wiblin, Nathan R, Gleeson, Fergus V, Bailey, Dalan, Sharpe, Sally, Charlton, Sue, Salguero, Francisco J, Carroll, Miles W, Gilbert, Sarah C
Published in Communications biology