Identification and structure–activity relationships of substituted pyridones as inhibitors of Pim-1 kinase by Cheney, I. Wayne, Yan, Shunqi, Appleby, Todd, Walker, Heli, Vo, Todd, Yao, Nanhua, Hamatake, Robert, Hong, Zhi, Wu, Jim Z.

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Phosphorylation of Ribavirin and Viramidine by Adenosine Kinase and Cytosolic 5′-Nucleotidase II: Implications for Ribavirin Metabolism in Erythrocytes by JIM ZHEN WU, LARSON, Gary, WALKER, Heli, JAE HOON SHIM, ZHI HONG

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Activation and Deactivation of a Broad-Spectrum Antiviral Drug by a Single Enzyme: Adenosine Deaminase Catalyzes Two Consecutive Deamination Reactions by Wu, Jim Zhen, Walker, Heli, Lau, Johnson Y N, Hong, Zhi

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Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila by MARSH, J. L, WALKER, H, THEISEN, H, ZHU, Y.-Z, FIELDER, T, PURCELL, J, THOMPSON, L. M

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Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes by Michailidou, Kyriaki, Fachal, Laura, Lee, Andrew, Wang, Qin, Yang, Xin, Adank, Muriel A., Aittomäki, Kristiina, Andrulis, Irene L., Antonenkova, Natalia N., Arndt, Volker, Auer, Paul L., Auvinen, Päivi, Barrdahl, Myrto, Beane Freeman, Laura E., Beckmann, Matthias W., Benitez, Javier, Bermisheva, Marina, Bogdanova, Natalia V., Bonanni, Bernardo, Brauch, Hiltrud, Brooks-Wilson, Angela, Brucker, Sara Y., Brüning, Thomas, Campa, Daniele, Chlebowski, Rowan, Cordina-Duverger, Emilie, Daly, Mary B., dos-Santos-Silva, Isabel, Dumont, Martine, Dwek, Miriam, Eliassen, A. Heather, Ellberg, Carolina, Evans, D. Gareth, Försti, Asta, Gabrielson, Marike, Gago-Dominguez, Manuela, García-Sáenz, José A., Gaudet, Mia M., Giles, Graham G., Gilyazova, Irina R., Grenaker Alnæs, Grethe I., Grip, Mervi, Gronwald, Jacek, Grundy, Anne, Hahnen, Eric, Hart, Steven N., Heyworth, Jane, Hoover, Robert N., Jakubowska, Anna, Jones, Michael E., Kaaks, Rudolf, Kerin, Michael J., Kiiski, Johanna I., Knight, Julia A., Krüger, Ute, Kühl, Tabea, Lambrechts, Diether, Lee, Eunjung, Lejbkowicz, Flavio, Lissowska, Jolanta, MacInnis, Robert J., Makalic, Enes, Maleva Kostovska, Ivana, Manoukian, Siranoush, Martinez, Maria Elena, McLean, Catriona, Menon, Usha, Miller, Nicola, Mulligan, Anna Marie, Neven, Patrick, Pérez-Barrios, Clara, Polley, Eric C., Prokofyeva, Darya, Purrington, Kristen, Pylkäs, Katri, Rack, Brigitte, Rau-Murthy, Rohini, Schmidt, Daniel F., Schmutzler, Rita K., Scott, Rodney J., Shu, Xiao-Ou, Slager, Susan, Southey, Melissa C., Stegmaier, Christa, Stone, Jennifer, Tamimi, Rulla M., Tapper, William J., Taylor, Jack A., Terry, Mary Beth, Tollenaar, Rob A.E.M., Tzardi, Maria, van Veen, Elke M., Weinberg, Clarice R., Yang, Xiaohong R., Zhang, Yan, Dunning, Alison M., Chenevix-Trench, Georgia, Milne, Roger L., Chatterjee, Nilanjan, Kraft, Peter

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Diagnosis and management of individuals with Fetal Valproate Spectrum Disorder; a consensus statement from the European Reference Network for Congenital Malformations and Intellect... by Clayton-Smith, Jill, Bromley, Rebecca, Dean, John, Journel, Hubert, Odent, Sylvie, Wood, Amanda, Williams, Janet, Cuthbert, Verna, Hackett, Latha, Aslam, Neelo, Malm, Heli, James, Gregory, Westbom, Lena, Day, Ruth, Ladusans, Edmund, Jackson, Adam, Bruce, Iain, Walker, Robert, Sidhu, Sangeet, Dyer, Catrina, Ashworth, Jane, Hindley, Daniel, Diaz, Gemma Arca, Rawson, Myfanwy, Turnpenny, Peter

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Efficient export of human growth hormone, interferon α2b and antibody fragments to the periplasm by the Escherichia coli Tat pathway in the absence of prior disulfide bond formatio... by Alanen, Heli I., Walker, Kelly L., Lourdes Velez Suberbie, M., Matos, Cristina F.R.O., Bönisch, Sarah, Freedman, Robert B., Keshavarz-Moore, Eli, Ruddock, Lloyd W., Robinson, Colin

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Heterogeneity in resistance training-induced muscle strength and mass responses in men and women of different ages by Ahtiainen, Juha P., Walker, Simon, Peltonen, Heikki, Holviala, Jarkko, Sillanpää, Elina, Karavirta, Laura, Sallinen, Janne, Mikkola, Jussi, Valkeinen, Heli, Mero, Antti, Hulmi, Juha J., Häkkinen, Keijo

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Resuscitative Endovascular Balloon Occlusion of the Aorta in Patients With Exsanguinating Hemorrhage\Resuscitative Endovascular Balloon Occlusion of the Aorta in Patients With Exsa... by Kamijo, Kyosuke, Matsumura, Yosuke, Aoki, Ryo, Tingerides, Constantinos, Walker, Paul, Kessel, Boris, Tal, Horer, Góes, Adenauer Marinho de Oliveira, Chin, Brian, Patel, Heli, Elkbuli, Adel, Jansen, Jan O, MacLennan, Graeme S, Campbell, Marion K

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Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants by Barnes, Daniel R., Rookus, Matti A., Dennis, Joe, Mavaddat, Nasim, Ahmed, Munaza, Aittomäki, Kristiina, Andrulis, Irene L., Arun, Banu K., Barkardottir, Rosa B., Barrowdale, Daniel, Benitez, Javier, Białkowska, Katarzyna, Blok, Marinus J., Bonanni, Bernardo, Bozsik, Aniko, Buys, Saundra S., Caldés, Trinidad, Campbell, Ian, Christensen, Lise Lotte, Colas, Chrystelle, Berthet, Pascaline, Faivre, Laurence, Giraud, Sophie, Lasset, Christine, Mebirouk, Noura, Adlard, Julian, Antoniou, Antonis, Brennan, Paul, Brewer, Carole, Cook, Jackie, Easton, Douglas, Eeles, Ros, Hanson, Helen, Izatt, Louise, Ong, Kai-ren, O’Shaughnessy-Kirwan, Aoife, Daly, Mary B., Davidson, Rosemarie, Ding, Yuan Chun, Dorfling, Cecilia M., Engel, Christoph, Evans, D. Gareth, Friedlander, Michael, Friedman, Eitan, Ganz, Patricia A., Gerdes, Anne-Marie, Giraud, Sophie, Glendon, Gord, Godwin, Andrew K., Gschwantler-Kaulich, Daphne, Hamann, Ute, Hu, Chunling, Hulick, Peter J., Hogervorst, Frans, Koudijs, Marco, Kruse, Torben A., Lazaro, Conxi, Lester, Jenny, Mai, Phuong L., Mari, Véronique, Meijers-Heijboer, Hanne E.J., Meindl, Alfons, Mensenkamp, Arjen R., Montagna, Marco, Mukherjee, Semanti, Mulligan, Anna Marie, Nevanlinna, Heli, Niederacher, Dieter, Olopade, Olufunmilayo I., Ott, Claus-Eric, Papi, Laura, Park, Sue K., Peissel, Bernard, Pfeiler, Georg, Phillips, Kelly-Anne, Prajzendanc, Karolina, Pujana, Miquel Angel, Ramus, Susan J., Rantala, Johanna, Rennert, Gad, Risch, Harvey A., Schuster, Hélène, Senter, Leigha, Side, Lucy E., Slavin, Thomas P., Soucy, Penny, Sutter, Christian, Thull, Darcy L., Toland, Amanda E., Tung, Nadine, van Engelen, Klaartje, van Rensburg, Elizabeth J., Wang-Gohrke, Shan, Wappenschmidt, Barbara, Yang, Xin, Zimbalatti, Dario, Offit, Kenneth, Couch, Fergus J., Schmutzler, Rita K., Antoniou, Antonis C.

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Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis by Martínez-Nieto, Guillermo A., Teppo, Hanna-Riikka, Petrelius, Noora, Izzi, Valerio, Devarajan, Raman, Petäistö, Tiina, Liu, Hengshuo, Kim, Kris S., Karppinen, Sanna-Maria, Ruotsalainen, Heli, Koivunen, Jarkko, Mäki, Joni M., Walker, Gilbert C., Pihlajaniemi, Taina, Gullberg, Donald, Heljasvaara, Ritva

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Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer by Aittomäki, Kristiina, Anton-Culver, Hoda, Arndt, Volker, Aronson, Kristan J, Arun, Banu K, Azzollini, Jacopo, Barnes, Daniel R, Beckmann, Matthias W, Bermisheva, Marina, Białkowska, Katarzyna, Blomqvist, Carl, Bolla, Manjeet K, Borg, Ake, Campbell, Ian, Carter, Jonathan, Chang-Claude, Jenny, Chanock, Stephen J, Christiansen, Hans, Couch, Fergus J, Dennis, Joe, Diez, Orland, Dunning, Alison M, Ejlertsen, Bent, Fasching, Peter A, Fletcher, Olivia, Flyger, Henrik, Friedman, Eitan, Frost, Debra, Gago-Dominguez, Manuela, Glendon, Gord, Goldgar, David E, González-Neira, Anna, Greene, Mark H, Guénel, Pascal, Hollestelle, Antoinette, Hoover, Robert N, Hopper, John L, Imyanitov, Evgeny N, Isaacs, Claudine, Jakimovska, Milena, Janavicius, Ramunas, Joseph, Vijai, Khusnutdinova, Elza, Ko, Yon-Dschun, Konstantopoulou, Irene, Lambrechts, Diether, Lazaro, Conxi, Leslie, Goska, Lesueur, Fabienne, Long, Jirong, Lubiński, Jan, Makalic, Enes, Mannermaa, Arto, Margolin, Sara, Maurer, Tabea, Mavroudis, Dimitrios, Meindl, Alfons, Menon, Usha, Michailidou, Kyriaki, Montagna, Marco, Moserle, Lidia, Mulligan, Anna Marie, Nevanlinna, Heli, Nevelsteen, Ines, Olsson, Håkan, Osorio, Ana, Park-Simon, Tjoung-Won, Parsons, Michael T, Pedersen, Inge Sokilde, Peixoto, Ana, Plaseska-Karanfilska, Dijana, Poppe, Bruce, Radice, Paolo, Rantala, Johanna, Rennert, Gad, Saloustros, Emmanouil, Schmutzler, Rita K, Simard, Jacques, Spurdle, Amanda B, Stone, Jennifer, Swerdlow, Anthony J, Tapper, William J, Teixeira, Manuel R, Teulé, Alex, Thomassen, Mads, Thöne, Kathrin, Tischkowitz, Marc, Toland, Amanda E, Truong, Thérèse, Tung, Nadine, Vachon, Celine M, van Rensburg, Elizabeth J, Viel, Alessandra, Wang, Qin, Wappenschmidt, Barbara, Weitzel, Jeffrey N, Winqvist, Robert, Kraft, Peter, Milne, Roger L, Beesley, Jonathan

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Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) by MAVADDAT, Nasim, BARROWDALE, Daniel, MULLIGAN, Anna Marie, COUCH, Fergus J, ENGEL, Christoph, MCGUFFOG, Lesley, HEALER, Sue, SINILNIKOVA, Olga M, SOUTHEY, Melissa C, TERRY, Mary Beth, GOLDGAR, David, O'MALLEY, Frances, ANDRULIS, Irene L, JOHN, Esther M, JANAVICIUS, Ramunas, TIHOMIROVA, Laima, HANSEN, Thomas V. O, NIELSEN, Finn C, OSORIO, Ana, STAVROPOULOU, Alexandra, BENITEZ, Javier, MANOUKIAN, Siranoush, PEISSEL, Bernard, DOMCHEK, Susan M, BARILE, Monica, VOLORIO, Sara, PASIN, Barbara, DOLCETTI, Riccardo, PUTIGNANO, Anna Laura, OTTINI, Laura, RADICE, Paolo, HAMANN, Ute, RASHID, Muhammad U, HOGERVORST, Frans B, ECCLES, Diana, KRIEGE, Mieke, VAN DER LUIJT, Rob B, HEBON, PEOCK, Susan, FROST, Debra, GARETH EVANS, D, BREWER, Carole, WALKER, Lisa, ROGERS, Mark T, SIDE, Lucy E, NEVANLINNA, Heli, HOUGHTON, Catherine, EMBRACE, WEAVER, Joellen, GODWIN, Andrew K, SCHMUTZLER, Rita K, WAPPENSCHMIDT, Barbara, MEINDL, Alfons, KAST, Karin, RAMUS, Susan J, SPURDLE, Amanda, ROBSON, Mark, SHERMAN, Mark

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Effects of general and central adiposity on circulating lipoprotein, lipid, and metabolite levels in UK Biobank: A multivariable Mendelian randomization study by Bell, Joshua A., Richardson, Tom G., Wang, Qin, Sanderson, Eleanor, Palmer, Tom, Walker, Venexia, O'Keeffe, Linda M., Timpson, Nicholas J., Cichonska, Anna, Julkunen, Heli, Würtz, Peter, Holmes, Michael V., Davey Smith, George

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ENIGMA-Evidence-based network for the interpretation of germline mutant alleles: An international initiative to evaluate risk and clinical significance associated with sequence var... by Spurdle, Amanda B., Healey, Sue, Devereau, Andrew, Hogervorst, Frans B. L., Monteiro, Alvaro N. A., Nathanson, Katherine L., Radice, Paolo, Stoppa-Lyonnet, Dominique, Tavtigian, Sean, Wappenschmidt, Barbara, Couch, Fergus J., Goldgar, David E.

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Network analysis to reveal the most commonly detected compounds in predator-prey pairs in freshwater and marine mammals and fish in Europe by Alygizakis, Nikiforos, Kostopoulou, Niki, Gkotsis, Georgios, Nika, Maria-Christina, Orfanioti, Anastasia, Ng, Kelsey, Bizani, Erasmia, Nikolopoulou, Varvara, Badry, Alexander, Brownlow, Andrew, Centelleghe, Cinzia, Chadwick, Elizabeth A., Ciesielski, Tomasz M., Cincinelli, Alessandra, Claßen, Daniela, Danielsson, Sara, Dekker, Rene W.R.J., Duke, Guy, Glowacka, Natalia, Gol'din, Pavel, Jansman, Hugh A.H., Jauniaux, Thierry, Knopf, Burkhard, Koschorreck, Jan, Krone, Oliver, Lekube, Xabier, Martellini, Tania, Movalli, Paola, O'Rourke, Emily, Oswald, Peter, Oswaldova, Martina, Saavedra, Camilo, Persson, Sara, Rohner, Simon, Roos, Anna, Routti, Heli, Schmidt, Britta, Sciancalepore, Giuseppe, Siebert, Ursula, Treu, Gabriele, van den Brink, Nico W., Vishnyakova, Karina, Walker, Lee Anthony, Thomaidis, Nikolaos S., Slobodnik, Jaroslav

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BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer by Mesman, Romy L S, Martin, Charlotte, Calléja, Fabienne M G R, Meeks, Huong, Hallberg, Emily, Hinton, Jamie, Lilyquist, Jenna, Hu, Chunling, Aalfs, Cora M, Aittomäki, Kristiina, Andrulis, Irene, Anton-Culver, Hoda, Arndt, Volker, Beckmann, Matthias W, Benitez, Javier, Bogdanova, Natalia V, Bojesen, Stig E, Bolla, Manjeet K, Borresen-Dale, Anne-Lise, Brauch, Hiltrud, Brennan, Paul, Brenner, Hermann, Brüning, Thomas, Burwinkel, Barbara, Chang-Claude, Jenny, Chenevix-Trench, Georgia, Choi, Ji-Yeob, Collée, J Margriet, Cross, Simon S, Czene, Kamila, Darabi, Hatef, Dennis, Joe, Dörk, Thilo, Dos-Santos-Silva, Isabel, Dunning, Alison M, Fasching, Peter A, Figueroa, Jonine, Flyger, Henrik, García-Closas, Montserrat, Giles, Graham G, Glendon, Gord, Guénel, Pascal, Haiman, Christopher A, Hamann, Ute, Hartman, Mikael, Hogervorst, Frans B, Hollestelle, Antoinette, Hopper, John L, Ito, Hidemi, Kang, Daehee, Lambrechts, Diether, Li, Jingmei, Lindblom, Annika, Lophatananon, Artitaya, Lubinski, Jan, Machackova, Eva, Mannermaa, Arto, Margolin, Sara, Matsuo, Keitaro, Miao, Hui, Milne, Roger L, Nevanlinna, Heli, Olson, Janet E, Olswold, Curtis, Oosterwijk, Jan J C, Osorio, Ana, Peterlongo, Paolo, Pharoah, Paul D P, Pylkäs, Katri, Radice, Paolo, Rhenius, Valerie, Rudolph, Anja, Sawyer, Elinor J, Schmidt, Marjanka K, Schoemaker, Minouk J, Shah, Mitul, Shen, Chen-Yang, Shrubsole, Martha, Southey, Melissa C, Swerdlow, Anthony, Tomlinson, Ian, Torres, Diana, Truong, Thérèse, van Asperen, Christi J, Wang, Qin, Winqvist, Robert, Wu, Anna H, Yu, Jyh-Cherng, Zheng, Wei, Zheng, Ying, Foretova, Lenka, Varesco, Liliana, Moghadasi, Setareh, Spurdle, Amanda, Devilee, Peter, Vrieling, Harry, Monteiro, Alvaro N A, Goldgar, David E, Carreira, Aura, Vreeswijk, Maaike P G

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A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers by Coignard, Juliette, Lush, Michael, O'Mara, Tracy A, McGuffog, Lesley, Leslie, Goska, Agata, Simona, Anton-Culver, Hoda, Arndt, Volker, Aronson, Kristan J, Arun, Banu K, Augustinsson, Annelie, Baynes, Caroline, Becher, Heiko, Bermisheva, Marina, Bernstein, Leslie, Białkowska, Katarzyna, Blomqvist, Carl, Burwinkel, Barbara, Buys, Saundra S, Caldés, Trinidad, Campa, Daniele, Chang-Claude, Jenny, Conroy, Don M, Czene, Kamila, Daly, Mary B, Devilee, Peter, Diez, Orland, Domchek, Susan M, Dos-Santos-Silva, Isabel, Evans, D Gareth, Fostira, Florentia, Friedman, Eitan, Fritschi, Lin, Frost, Debra, Gapstur, Susan M, Garcia-Barberan, Vanesa, Gaudet, Mia M, Georgoulias, Vassilios, González-Neira, Anna, Greene, Mark H, Haiman, Christopher A, Harrington, Patricia A, He, Wei, Jager, Agnes, Jakubowska, Anna, James, Paul A, Khusnutdinova, Elza, Kiiski, Johanna I, Ko, Yon-Dschun, Laitman, Yael, Le Marchand, Loic, Lester, Jenny, Lesueur, Fabienne, Lopez-Fernández, Adria, Luccarini, Craig, Manoukian, Siranoush, Mebirouk, Noura, Montagna, Marco, Nathanson, Katherine L, Neuhausen, Susan L, Nevanlinna, Heli, O'Brien, Katie M, Olson, Janet E, Osorio, Ana, Parsons, Michael T, Pedersen, Inge Sokilde, Peterlongo, Paolo, Phillips, Kelly-Anne, Polley, Eric C, Punie, Kevin, Radice, Paolo, Rashid, Muhammad U, Rennert, Gad, Rennert, Hedy S, Robson, Mark, Saloustros, Emmanouil, Santella, Regina, Schmidt, Marjanka K, Scott, Christopher, Sharma, Priyanka, Tapper, William J, Teulé, Alex, Tischkowitz, Marc, Trainer, Alison H, Vachon, Celine M, Vijai, Joseph, Wang, Qin, Weitzel, Jeffrey N, Wendt, Camilla, Wolk, Alicja, Yang, Xiaohong R, Yannoukakos, Drakoulis, Ziogas, Argyrios, Zorn, Kristin K, Park, Sue K, Offit, Kenneth, Schmutzler, Rita K, Couch, Fergus J, Chenevix-Trench, Georgia, Antoniou, Antonis C

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Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus by Lawrenson, Kate, Kuchenbaeker, Karoline, Aittomäki, Kristiina, Arun, Banu K, Arver, Brita, Bandera, Elisa V, Barrowdale, Daniel, Benitez, Javier, Bjorge, Line, Bojesen, Anders, Bojesen, Stig E, Brauch, Hiltrud, Bruinsma, Fiona, Brunet, Joan, Buhari, Shaik Ahmad, Butzow, Ralf, Cai, Qiuyin, Campbell, Ian, Canniotto, Rikki, Choi, Ji-Yeob, Cox, Angela, Cybulski, Cezary, Daly, Mary B, Dansonka-Mieszkowska, Agnieszka, Dennis, Joe, Doherty, Jennifer A, Ehrencrona, Hans, Ellis, Steve, Engel, Christoph, Fasching, Peter A, Feliubadalo, Lidia, Fletcher, Olivia, Foulkes, William D, García-Closas, Montserrat, Gentry-Maharaj, Aleksandra, Giles, Graham G, Godwin, Andrew K, Goldberg, Mark S, Goldgar, David E, González-Neira, Anna, Goodman, Marc T, Gronwald, Jacek, Hallberg, Emily, Hansen, Thomas V O, Heitz, Florian, Høgdall, Claus K, Hopper, John L, Huzarski, Tomasz, Janavicius, Ramunas, Johnson, Nichola, Kabisch, Maria, Khan, Sofia, Kosma, Veli-Matti, Kristensen, Vessela, Kupryjanczyk, Jolanta, Kwong, Ava, Lester, Jenny, Lu, Karen, Margolin, Sara, Marme, Frederik, McLean, Catriona, Meindl, Alfons, Montagna, Marco, Moysich, Kirsten B, Ness, Roberta B, Nord, Silje, Olson, Janet E, Olswold, Curtis, O'Malley, David, Orr, Nick, Osorio, Ana, Pearce, Celeste L, Pejovic, Tanja, Pfeiler, Georg, Phelan, Catherine M, Poole, Elizabeth M, Radice, Paolo, Rantala, Johanna, Rashid, Muhammad Usman, Rossing, Mary Anne, Sangrajrang, Suleeporn, Sawyer, Elinor J, Seynaeve, Caroline, Sinilnikova, Olga M, Teixeira, Manuel R, Tseng, Chiu-Chen, Vanderstichele, Adriaan, Wang, Qin, Weitzel, Jeffrey N, Wentzensen, Nicolas, Whittemore, Alice S, Wildiers, Hans, Wu, Anna H, Yannoukakos, Drakoulis, Zheng, Wei, Simard, Jacques, Easton, Douglas F, Dunning, Alison M, Edwards, Stacey L, Antoniou, Antonis C

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Preferential thermal nitridation to form pin-hole free Cr-nitrides to protect proton exchange membrane fuel cell metallic bipolar plates by Brady, M.P., Weisbrod, K., Paulauskas, I., Buchanan, R.A., More, K.L., Wang, H., Wilson, M., Garzon, F., Walker, L.R.

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