Karel ende Elegast

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Redesigning the debate

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Plant-derived metabolites with synergistic antioxidant activity by Beukelman, Cees J., Van den Berg, Albert J.J., Kroes, Burt H., Labadie, Rudi P., Mattsson, Eva E., Vans Dijk, Hans

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The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial by Westendorp, Willeke F, MD, Vermeij, Jan-Dirk, MD, Zock, Elles, MSc, Hooijenga, Imke J, MA, Kruyt, Nyika D, MD, Bosboom, Hans J L W, MD, Kwa, Vincent I H, MD, Weisfelt, Martijn, MD, Remmers, Michel J M, MD, ten Houten, Robert, MD, Schreuder, A H C M (Tobien), MD, Vermeer, Sarah E, MD, van Dijk, Ewout J, MD, Dippel, Diederik W J, Prof, Dijkgraaf, Marcel G W, PhD, Spanjaard, Lodewijk, MD, Vermeulen, Marinus, Prof, van der Poll, Tom, Prof, Prins, Jan M, Prof, Vermeij, Frederique H, MD, Roos, Yvo B W E M, Prof, Kleyweg, Ruud P, MD, Kerkhoff, Henk, MD, Brouwer, Matthijs C, MD, Zwinderman, Aeilko H, Prof, van de Beek, Diederik, Prof, Nederkoorn, Paul J, MD

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Chemotherapy versus chemoradiotherapy after surgery and preoperative chemotherapy for resectable gastric cancer (CRITICS): an international, open-label, randomised phase 3 trial by Cats, Annemieke, Jansen, Edwin P M, van Grieken, Nicole C T, Sikorska, Karolina, Lind, Pehr, Nordsmark, Marianne, Meershoek-Klein Kranenbarg, Elma, Boot, Henk, Trip, Anouk K, Swellengrebel, H A Maurits, van Laarhoven, Hanneke W M, Putter, Hein, van Sandick, Johanna W, van Berge Henegouwen, Mark I, Hartgrink, Henk H, van Tinteren, Harm, van de Velde, Cornelis J H, Verheij, Marcel, Van Coevorden, Frits, Vanhoutvin, Steven, Hulshof, Maarten CCM, Loosveld, Olaf JL, Ten Tije, A (Bert) Jan, Erdkamp, Frans LG, Warmerdam, Fabienne ARM, Van der Peet, Donald L, Verheul, Henk MW, Boerma, Djamila, Los, Maartje, Slot, Annerie, Houtsma, Danny, Portielje, Johanna EA, Blaisse, Reinoud JB, Spillenaar Bilgen, Ernst Jan, Polée, Marco B, Geenen, Maud M, Braak, Jeffrey PBM, Neelis, Karen J, Slingerland, Marije, Jansen, Rob LH, Buijsen, Jeroen, Beeker, Aart, Eijsbouts, Quirijn AJ, Van Riel, Johanna MGH, Rozema, Tom, Van Spronsen, Dick Johan, Meerum Terwogt, Jetske M, Tanis, Bea C, Van der Torren-Conze, Adelheid ME, Van Hilligersberg, Richard, Koopman, Miriam, Den Boer, Marien O, Creemers, Geert-Jan, Van der Sangen, Maurice, Rentinck, Marjolein EM, Van den Berg, H Pieter, Jonkers, Ge JPM, Grootenboers, Diane, Vulink, Annelie JE, Hovenga, Sjoerd, Van der Mijle, Huub CJ, Baars, Arnold, Haringhuizen, Annebeth W, Appels, Marije IE, Rietbroek, Ron C, Hendriksen, Ellen M, Legdeur, Marie-Cecile JC, Ten Bokkel Huinink, Daan, Van Dobbenburgh, O Aart, Smit, Jitty M, Van Bochove, Aart, Veldhuis, Gerrit-Jan, Muller, Erik W, Bonenkamp, J (Han) J, Braam, Pètra M, De Boer, Jaap, Van Halteren, Henk K, Valster, Fransje AA, Imholz, Alex LT, Van Dijk, Marjan A, Van der Gaast, Ate, Otten, J (Hans)-Martin MB, Ceha, Heleen M, Glimelius, Bengt, Lagerbäck, Cecillia, Perman, Mats, Johnsson, Anders, Borg, David, Nielsen, Niels H, Piwowar, Andrzej, Elmlund, Mattias, Hörberg, Helene, Edlund, Per, Johansson, Bengt, Flygare, Petra, Jespersen, Marie Louise

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Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data by Lingsma, Hester, Brown, B Scott, Hill, Michael D, Yoo, Albert J, Gerrits, Dick G., Karas, Giorgos B., Flach, Zwenneke, Andersson, Tommy, Borst, Jordi, Jansen, Ivo, Ryckborst, KJ, Sapkota, B, Lacusta, S, Derdeyn, C, Brant, R, Aram, H, Desai, J, van Dijk, R, Schwindt, B, Butcher, KS, Jeerakathil, T, Daly, T, Totoraitis, V, Rangaraju, S, Jaigobin, C, ter Brugge, K, Quarfordt, S, Pratt, R, Robert, S, Lesiuk, H, Blue-Schaller, A, Hesser, K, Gladstone, D, Boyle, K, Vandorpe, R, Burns, PA, Azizi, A, Kostyrko, P, Kim, DJ, Rho, S, Kim, KH, Oxley, Thomas J, Coulton, Bronwyn, Diener, Hans-Christoph, Hacke, Werner, Jovin, Tudor G., Sanossian, Nerses, Loh, Yince, Horev, A, Amerson, L, Vora, N, Takahasi, C, Hui, F, Möhlenbruch, M, Sombutmai, C, Skaletsky, M, Kastrup, A, Cate, C, Kahles, T, Krützelmann, A, Holst, B, Noorian, A, Pafford, R, Haring, H-P, Tummala, R, Martin, C, Crandall, S, Kreiser, K, Boeckh-Behrens, T, Koch, ML, Meindl, T, Meler, P, Tomasello, A, Muñoz, L, Cano, L, Cobo, E, Ducrocq, Xavier, Rosso, Charlotte, Estrade, Laurent, Renkes, Céline, Desal, Hubert, Herisson, Fanny, Cahagne, Vincent, Lamy, Catherine, Chabriat, Hugues, Mawet, Jérôme, Saint-Maurice, Jean-Pierre, Gueguen, Antoine, Marques, Anna-Raquel, Detante, Olivier, Rodesch, Georges, Melki, Elsa, Deplanque, Dominique, Girot, Marie, Mouton, Servane, Hervé, Deramond, Roffe, Christine, Kandasamy, Naga, Lenthall, Rob, Banaras, Azra

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Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease by Robak, Laurie A, Jansen, Iris E, van Rooij, Jeroen, Uitterlinden, André G, Kraaij, Robert, Jankovic, Joseph, Heutink, Peter, Shulman, Joshua M

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Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy by Lesage, Suzanne, Deramecourt, Vincent, Jacoupy, Maxime, Hassoun, Sidi Mohamed, Pujol, Claire, Maurage, Claude-Alain, Sahbatou, Mourad, Liebau, Stefan, Bilgic, Basar, Emre, Murat, Erginel-Unaltuna, Nihan, Guven, Gamze, Tison, François, Tranchant, Christine, Corvol, Jean-Christophe, Krack, Paul, Hernandez, Dena G., Gibbs, J. Raphael, Hardy, John, Wood, Nicholas W., Durr, Alexandra, Deleuze, Jean-François, Tazir, Meriem, Destée, Alain, Lohmann, Ebba, Corti, Olga, Brice, Alexis, Lesage, Suzanne, Tison, François, Vidailhet, Marie, Corvol, Jean-Christophe, Agid, Yves, Anheim, Mathieu, Bonnet, Anne-Marie, Borg, Michel, Broussolle, Emmanuel, Durif, Franck, Krack, Paul, Klebe, Stephan, Lohmann, Ebba, Vérin, Marc, Viallet, François, Brice, Alexis, Majounie, Elisa, Corvol, Jean Christophe, Ben-Shlomo, Yoav, Berg, Daniela, Bhatia, Kailash, Bochdanovits, Zoltan, Bonin, Michael, Bras, Jose M., Brockmann, Kathrin, Burn, David J., Chen, Honglei, Clarke, Carl E., Cookson, Mark R., Counsell, Carl, van Dijk, Karin D., Dong, Jing, Escott-Price, Valentina, Evans, Jonathan R., Gray, Emma, Guerreiro, Rita, van Hilten, Jacobus J., Hollenbeck, Albert, Holmans, Peter, Hu, Michèle, Hudson, Gavin, Hunt, Sarah E., Kilarski, Laura L., Jansen, Iris E., Langford, Cordelia, Lees, Andrew, Lorenz, Delia, Lubbe, Steven, Lungu, Codrin, Martinez, María, Mätzler, Walter, McNeill, Alisdair, Moorby, Catriona, O’Sullivan, Sean S., Pearson, Justin, Ravina, Bernard, Rivadeneira, Fernando, Ryten, Mina, Schapira, Anthony, Sharma, Manu, Sheerin, Una-Marie, Sidransky, Ellen, Spencer, Chris C.A., Stefánsson, Kári, Strange, Amy, Talbot, Kevin, Trabzuni, Daniah, Uitterlinden, André G., van de Warrenburg, Bart, Williams-Gray, Caroline H., Winder-Rhodes, Sophie, Hardy, John, Wood, Nicholas W.

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Clinical Performance of the Low Profile Zenith Alpha Abdominal Endovascular Graft: 2 Year Results from the ZEPHYR Registry by Hatzl, Johannes, van Basten Batenburg, Michiel, Yeung, Kak K., Fioole, Bram, Verhoeven, Eric, Lauwers, Geert, Kölbel, Tilo, Wever, Jan J., Scheinert, Dierk, Van den Eynde, Wouter, Rouhani, Guido, Mees, Barend M.E., Vermassen, Frank, Schelzig, Hubert, Böckler, Dittmar, Cuypers, Philippe W.M., Katsargyris, Athanasios, Van Overhagen, Hans, Verbist, Jurgen, Schurink, Geert W.H., Statius van Eps, Randolph G., Veger, Hugo T.C., Rohlffs, Fiona, Panuccio, Giuseppe, Van Dijk, Lukas C.

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Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease by Beilina, Alexandria, Rudenko, Iakov N., Kaganovich, Alice, Civiero, Laura, Chau, Hien, Kalia, Suneil K., Kalia, Lorraine V., Lobbestael, Evy, Chia, Ruth, Ndukwe, Kelechi, Ding, Jinhui, Nalls, Mike A., Olszewski, Maciej, Hauser, David N., Kumaran, Ravindran, Lozano, Andres M., Baekelandt, Veerle, Greene, Lois E., Taymans, Jean-Marc, Greggio, Elisa, Cookson, Mark R.

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Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier by Khalil, Ramzi, Boels, Margien G. S., van den Berg, Bernard M., Bruijn, Jan A., Rabelink, Ton J., Hogendoorn, Pancras C. W., Baelde, Hans J.

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Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption by Byrne, Enda M, Esko, Tõnu, Nalls, Michael A, Monda, Keri L, Amin, Najaf, Renstrom, Frida, Cavadino, Alana, Nolte, Ilja M, Teumer, Alexander, Yu, Kai, Marques-Vidal, Pedro, Manichaikul, Ani, Wojczynski, Mary K, Vink, Jacqueline M, Mikkilä, Vera, Eriksson, Joel, Musani, Solomon K, Geller, Frank, Luan, Jian'an, Garcia, Melissa E, Wright, Margaret J, Magnusson, Patrik Ke, Oostra, Ben A, Ikram, Mohammad Arfan, Uitterlinden, Andre G, Johansson, Ingegerd, Kaakinen, Marika, Milani, Lili, Power, Chris, Snieder, Harold, Stolk, Ronald P, Baumeister, Sebastian E, Biffar, Reiner, Gu, Fangyi, Kutalik, Zoltán, Forouhi, Nita G, Mihailov, Evelin, Lind, Lars, Lindgren, Cecilia, Michaëlsson, Karl, Morris, Andrew, Khaw, Kay-Tee, Wang, Jie Jin, Männistö, Satu, Perälä, Mia-Maria, Lehtimäki, Terho, Mozaffarian, Dariush, Psaty, Bruce M, Döring, Angela, Montgomery, Grant W, Melbye, Mads, Treur, Jorien L, Mellström, Dan, Hottenga, Jouke Jan, Prokopenko, Inga, Tönjes, Anke, Deloukas, Panos, Kanoni, Stavroula, Houston, Denise K, Liu, Yongmei, Mason, Marc A, Zonderman, Alan B, Franke, Lude, Kristal, Bruce S, Karjalainen, Juha, Reed, Danielle R, Westra, Harm-Jan, Saleheen, Danish, Harris, Tamara B, Dedoussis, George, Curhan, Gary, Pasquale, Louis R, Ordovas, Jose M, Peters, Ulrike, Ohlsson, Claes, Gieger, Christian, Martin, Nicholas G, Waldenberger, Melanie, Siscovick, David S, Raitakari, Olli, Hunter, David J, Kraft, Peter, Borecki, Ingrid B, Loos, Ruth Jf, Wareham, Nicholas J, Vollenweider, Peter, Caporaso, Neil, Grabe, Hans Jörgen, Neuhouser, Marian L, Wolffenbuttel, Bruce Hr, Hu, Frank B, Järvelin, Marjo-Riitta, Cupples, L Adrienne, Ridker, Paul M, van Duijn, Cornelia M, Metspalu, Andres, North, Kari E, Ingelsson, Erik, van Dam, Rob M, Chasman, Daniel I

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Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies by Nalls, Michael A, Plagnol, Vincent, Hernandez, Dena G, Sharma, Manu, Sheerin, Una-Marie, Saad, Mohamad, Simón-Sánchez, J, Schulte, Claudia, Lesage, Suzanne, Sveinbjörnsdóttir, Sigurlaug, Stefánsson, Kári, Martinez, Maria, Hardy, John, Heutink, Peter, Brice, Alexis, Gasser, Thomas, Singleton, Andrew B, Wood, Nicholas W

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Lung-function trajectories: relevance and implementation in clinical practice by Melén, Erik, Faner, Rosa, Allinson, James P, Bui, Dinh, Bush, Andrew, Custovic, Adnan, Garcia-Aymerich, Judith, Guerra, Stefano, Breyer-Kohansal, Robab, Hallberg, Jenny, Lahousse, Lies, Martinez, Fernando D, Merid, Simon Kebede, Powell, Pippa, Pinnock, Hilary, Stanojevic, Sanja, Vanfleteren, Lowie E G W, Wang, Gang, Dharmage, Shyamali C, Wedzicha, Jadwiga, Agusti, Alvar, Abellan, Alicia, Adcock, Ian, Afzal, Shoaib, Alter, Peter, Backman, Helena, Bertels, Xander, Bloom, Chloe, Bønnelykke, Klaus, Breyer, Marie-Kathrin, Casas, Sandra, Chung, Fan (Kian), Colak, Yunus, Cosio, Borja G., Duijts, Liesbeth, Fabbri, Leonardo, Fontanella, Sara, Fuertes, Elaine, Gonzalez, Juan Ramón, Granell, Raquel, Hartl, Sylvia, Hernandez-Pacheco, Natalia, Holloway, John, Jarvis, Deborah, Koefoed, Hans Jacob, Kole, Tessa, Kumar, Ashish, Langhammer, Arnulf, Lindberg, Anne, Llopis, Maria, Maitland van der Zee, Anke-Hilse, Meteran, Howraman, Minelli, Cosetta, Nwaru, Bright, Olvera, Nuria, Peralta, Gabriela, Ritchie, Andrew, Rönmark, Eva, Ross Chapman, James, Sangüesa Boix, Júlia, Schikowski, Tamara, Schlünssen, Vivi, Shaheen, Seif, Sigsgaard, Torben, Standl, Marie, Talaei, Mohammad, Ullah, Anhar, Ullman, Anders, Valencia-Hernandez, Carlos, van den Berge, Maarten, van Dijk, Yoni, Vestbo, Jørgen, Vijverberg, Susanne, Vikjord, Sigrid Anna, Volgelmeier, Claus, Vonk, Judith, Zounemat Kermani, Nazanin

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Deep learning-based white matter lesion volume on CT is associated with outcome after acute ischemic stroke by van Voorst, Henk, Pitkänen, Johanna, van Poppel, Laura, de Vries, Lucas, Mojtahedi, Mahsa, Martou, Laura, Emmer, Bart J., Roos, Yvo B. W. E. M., van Oostenbrugge, Robert, Postma, Alida A., Marquering, Henk A., Majoie, Charles B. L. M., Curtze, Sami, Melkas, Susanna, Bentley, Paul, Caan, Matthan W. A.

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Functional and Clinical Outcomes After Plate Osteosynthesis Versus Intramedullary Nailing of a Humeral Shaft Fracture: The Results of the HUMMER Multicenter, Prospective Cohort Stu... by Den Hartog, Dennis, Mahabier, Kiran C, Van Bergen, Saskia H, Verhofstad, Michael H J, Van Lieshout, Esther M M

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Deeper penetration of erythrocytes into the endothelial glycocalyx is associated with impaired microvascular perfusion by Lee, Dae Hyun, Dane, Martijn J C, van den Berg, Bernard M, Boels, Margien G S, van Teeffelen, Jurgen W, de Mutsert, Renée, den Heijer, Martin, Rosendaal, Frits R, van der Vlag, Johan, van Zonneveld, Anton Jan, Vink, Hans, Rabelink, Ton J

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Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing by Jansen, Iris E, Ye, Hui, Heetveld, Sasja, Lechler, Marie C, Michels, Helen, Seinstra, Renée I, Lubbe, Steven J, Drouet, Valérie, Lesage, Suzanne, Majounie, Elisa, Gibbs, J Raphael, Nalls, Mike A, Ryten, Mina, Botia, Juan A, Vandrovcova, Jana, Simon-Sanchez, Javier, Castillo-Lizardo, Melissa, Rizzu, Patrizia, Blauwendraat, Cornelis, Chouhan, Amit K, Li, Yarong, Yogi, Puja, Amin, Najaf, van Duijn, Cornelia M, Morris, Huw R, Brice, Alexis, Singleton, Andrew B, David, Della C, Nollen, Ellen A, Jain, Shushant, Shulman, Joshua M, Heutink, Peter

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Posterolateral or direct lateral approach for cemented hemiarthroplasty after femoral neck fracture (APOLLO): protocol for a multicenter randomized controlled trial with economic e... by Tol, Maria C J M, Willigenburg, Nienke W, Willems, Hanna C, Gosens, Taco, Rasker, Ariena, Heetveld, Martin J, Schotanus, Martijn G M, Van Dongen, Johanna M, Eggen, Bart, Kormos, Mate, Van der Pas, Stéphanie L, Van der Vaart, Aad W, Poolman, Rudolf W

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A two-stage meta-analysis identifies several new loci for Parkinson's disease

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