Artemisinin Blocks Prostate Cancer Growth and Cell Cycle Progression by Disrupting Sp1 Interactions with the Cyclin-dependent Kinase-4 (CDK4) Promoter and Inhibiting CDK4 Gene Expr...

by Willoughby, Jamin A., Sundar, Shyam N., Cheung, Mark, Tin, Antony S., Modiano, Jaime, Firestone, Gary L.
Published in The Journal of biological chemistry

DNA Damage Baseline Predicts Resilience to Space Radiation and Radiotherapy

by Pariset, Eloise, Bertucci, Antonella, Petay, Margaux, Malkani, Sherina, Lopez Macha, Alejandra, Paulino Lima, Ivan G., Gomez Gonzalez, Vanesa, Tin, Antony S., Tang, Jonathan, Plante, Ianik, Cekanaviciute, Egle, Vazquez, Marcelo, Costes, Sylvain V.
Published in Cell reports (Cambridge)

Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells

by Tin, Antony S, Park, Anna H, Sundar, Shyam N, Firestone, Gary L
Published in BMC biology

Correction: Gadolinium-enhanced cardiac MR exams of human subjects are associated with significant increases in the DNA repair marker 53BP1, but not the damage marker γH2AX

by McDonald, Jennifer S, McDonald, Robert J, Ekins, Jacob B, Tin, Antony S, Costes, Sylvain, Hudson, Tamara M, Schroeder, Dana J, Kallmes, Kevin, Kaufmann, Scott H, Young, Philip M, Lu, Aiming, Kadirvel, Ramanathan, Kallmes, David F
Published in PloS one

Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promote...

by MARCONETT, Crystal N, SUNDAR, Shyam N, TSENG, Min, TIN, Antony S, TRAN, Kalvin Q, MAHURON, Kelly M, BJELDANES, Leonard F, FIRESTONE, Gary L
Published in Carcinogenesis (New York)

Treatment Response Monitoring Using a Tumor-Informed Circulating Tumor DNA Test in an Advanced Triple-Negative Breast Cancer Patient: A Case Report

by Azzi, Georges, Krinshpun, Shifra, Tin, Antony, Maninder, Minu, Malashevich, Allyson Koyen, Malhotra, Meenakshi, Vega, Ruben Ruiz, Billings, Paul R., Rodriguez, Angel, Aleshin, Alexey
Published in Case reports in oncology

25 Line of therapy adjustment in a patient with advanced triple-negative breast cancer (TNBC) by using personalized ctDNA test for treatment response monitoring

by Azzi, Georges, Krinshpun, Shifra, Tin, Antony, Malashevich, Allyson, Malhotra, Meenakshi, Billings, Paul, Rodriguez, Angel, Aleshin, Alexey
Published in Journal for immunotherapy of cancer

Role of Circulating Tumor DNA As a Prognostic Biomarker in Patients with Diffuse Large B-Cell Lymphoma

by Narkhede, Mayur S., Tomassetti, Sarah, Iqbal, Madiha, Tin, Antony, Rivero-Hinojosa, Samuel, George, Giby V., Widden, Hayley, Benrud, Ryan, Rodriguez, Angel, Liu, Minetta C.
Published in Blood

Abstract 569: Correlation of variant allele frequency and mean tumor molecules with tumor burden in patients with solid tumors

by Tin, Antony, Aushev, Vasily, Kalashnikova, Ekaterina, Salari, Raheleh, Shchegrova, Svetalana, Fehringer, Gordon, Malhotra, Meenakshi, Ravi, Harini, Sethi, Himanshu, Brevnov, Maxim, Zimmermann, Bernhard, Rodriguez, Angel, Billings, Paul R., Aleshin, Alexey
Published in Cancer research (Chicago, Ill.)

Correlation between variant allele frequency and mean tumor molecules with tumor burden in patients with solid tumors

by Kalashnikova, Ekaterina, Aushev, Vasily N, Malashevich, Allyson Koyen, Tin, Antony, Krinshpun, Shifra, Salari, Raheleh, Scalise, Carly Bess, Ram, Rosalyn, Malhotra, Meenakshi, Ravi, Harini, Sethi, Himanshu, Sanchez, Stephanie, Hagelstrom, Robert Tanner, Brevnov, Maxim, Rabinowitz, Matthew, Moshkevich, Solomon, Zimmermann, Bernhard G, Liu, Minetta C, Aleshin, Alexey
Published in Molecular oncology

Abstract PD9-02: Personalized ctDNA as a predictive biomarker in high-risk early stage breast cancer (EBC) treated with neoadjuvant chemotherapy (NAC) with or without pembrolizumab...

by Magbanua, Mark Jesus M, Wolf, Denise, Renner, Derrick, Shchegrova, Svetlana, Swigart, Lamorna Brown, Yau, Christina, Hirst, Gillian, Wu, Hsin-Ta, Kalashnikova, Ekaterina, Tin, Antony, Delson, Amy, Yee, Douglas, DeMichele, Angela, Salari, Raheleh, Rodriguez, Angel, Zimmermann, Bernhard, Sethi, Himanshu, Aleshin, Alexey, Billings, Paul, Esserman, Laura, Liu, Minetta, Nanda, Rita, van ‘t Veer, Laura
Published in Cancer research (Chicago, Ill.)

Abstract P5-01-04: Personalized monitoring of circulating tumor DNA during neoadjuvant therapy in high-risk early stage breast cancer reflects response and risk of metastatic recur...

by Magbanua, Mark Jesus M, Brown-Swigart, Lamorna, Hirst, Gillian, Yau, Christina, Wolf, Denise, Wu, Hsin-Ta, Tin, Antony, Shchegrova, Svetlana, Sethi, Himanshu, Salari, Raheleh, Aleshin, Alexey, Louie, Maggie, Zimmermann, Bernhard, DeMichele, Angela, Liu, Minetta, Delson, Amy, Chien, Amy Jo, Asare, Smita, Esserman, Laura, van't Veer, Laura
Published in Cancer research (Chicago, Ill.)

Correction: Gadolinium-enhanced cardiac MR exams of human subjects are associated with significant increases in the DNA repair marker 53BP1, but not the damage marker [gamma]H2AX

by McDonald, Jennifer S, McDonald, Robert J, Ekins, Jacob B, Tin, Antony S, Costes, Sylvain, Hudson, Tamara M, Schroeder, Dana J, Kallmes, Kevin, Kaufmann, Scott H, Young, Philip M, Lu, Aiming, Kadirvel, Ramanathan, Kallmes, David F
Published in PloS one

Abstract 913: Early detection of metastatic relapse and monitoring of therapeutic efficacy by ultra-deep sequencing of plasma cell-free DNA in patients with urothelial bladder carc...

by Christensen, Emil, Birkenkamp-Demtröder, Karin, Sethi, Himanshu, Shchegrova, Svetlana, Salari, Raheleh, Nordentoft, Iver, Wu, Hsin-Ta, Knudsen, Michael, Lamy, Philippe, Lindskrog, Sia V., Taber, Ann, Balcioglu, Mustafa, Vang, Søren, Assaf, Zoe, Sharma, Shruti, Tin, Antony S., Srinivasan, Ramya, Hafez, Dina, Reinert, Thomas, Navarro, Samantha, Olson, Alexander, Ram, Rosie, Dashner, Scott, Rabinowitz, Matthew, Billings, Paul, Sigurjonsson, Styrmir, Andersen, Claus L., Swenerton, Ryan, Aleshin, Alexey, Zimmermann, Bernhard G., Agerbæk, Mads, Lin, Cheng-Ho J., Jensen, Jørgen B., Dyrskjøt, Lars
Published in Cancer research (Chicago, Ill.)

Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promote...

by Marconett, Crystal N, Sundar, Shyam N, Tseng, Min, Tin, Antony S, Tran, Kalvin Q, Mahuron, Kelly M, Bjeldanes, Leonard F, Firestone, Gary L
Published in Carcinogenesis (New York)

Treatment Response Monitoring Using a Tumor-Informed Circulating Tumor DNA Test in an Advanced Triple-Negative Breast Cancer Patient: A Case Report

by Azzi, Georges, Krinshpun, Shifra, Tin, Antony, Maninder, Minu, Malashevich, Allyson Koyen, Malhotra, Meenakshi, Vega, Ruben Ruiz, Billings, Paul R, Rodriguez, Angel, Aleshin, Alexey
Published in Case reports in oncology

Obligatory Role for B Cells in the Development of Angiotensin II-Dependent Hypertension

by Chan, Christopher T, Sobey, Christopher G, Lieu, Maggie, Ferens, Dorota, Kett, Michelle M, Diep, Henry, Kim, Hyun Ah, Krishnan, Shalini M, Lewis, Caitlin V, Salimova, Ekaterina, Tipping, Peter, Vinh, Antony, Samuel, Chrishan S, Peter, Karlheinz, Guzik, Tomasz J, Kyaw, Tin S, Toh, Ban-Hock, Bobik, Alexander, Drummond, Grant R
Published in Hypertension (Dallas, Tex. 1979)

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

by Gharahkhani, Puya, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P, Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W, Segrè, Ayellet V, Rouhana, John M, Hamel, Andrew R, Igo, Jr, Robert P, Choquet, Helene, Qassim, Ayub, Josyula, Navya S, Cooke Bailey, Jessica N, Bonnemaijer, Pieter W M, Iglesias, Adriana, Siggs, Owen M, Young, Terri L, Vitart, Veronique, Thiadens, Alberta A H J, Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B, Nair, K Saidas, Luben, Robert, Simcoe, Mark, Amersinghe, Nishani, Cree, Angela J, Hohn, Rene, Poplawski, Alicia, Chen, Li Jia, Rong, Shi-Song, Aung, Tin, Vithana, Eranga Nishanthie, Tamiya, Gen, Shiga, Yukihiro, Yamamoto, Masayuki, Nakazawa, Toru, Currant, Hannah, Birney, Ewan, Wang, Xin, Auton, Adam, Lupton, Michelle K, Martin, Nicholas G, Ashaye, Adeyinka, Olawoye, Olusola, Williams, Susan E, Akafo, Stephen, Ramsay, Michele, Hashimoto, Kazuki, Kamatani, Yoichiro, Akiyama, Masato, Momozawa, Yukihide, Foster, Paul J, Khaw, Peng T, Morgan, James E, Strouthidis, Nicholas G, Kraft, Peter, Kang, Jae H, Pang, Chi Pui, Pasutto, Francesca, Mitchell, Paul, Lotery, Andrew J, Palotie, Aarno, van Duijn, Cornelia, Haines, Jonathan L, Hammond, Chris, Pasquale, Louis R, Klaver, Caroline C W, Hauser, Michael, Khor, Chiea Chuen, Mackey, David A, Kubo, Michiaki, Cheng, Ching-Yu, Craig, Jamie E, MacGregor, Stuart, Wiggs, Janey L
Published in Nature communications

Genetics in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

by Köttgen, Anna, Cornec-Le Gall, Emilie, Halbritter, Jan, Kiryluk, Krzysztof, Mallett, Andrew J., Parekh, Rulan S., Rasouly, Hila Milo, Sampson, Matthew G., Tin, Adrienne, Antignac, Corinne, Ars, Elisabet, Bergmann, Carsten, Bleyer, Anthony J., Bockenhauer, Detlef, Devuyst, Olivier, Florez, Jose C., Fowler, Kevin J., Franceschini, Nora, Fukagawa, Masafumi, Gale, Daniel P., Gbadegesin, Rasheed A., Goldstein, David B., Grams, Morgan E., Greka, Anna, Gross, Oliver, Guay-Woodford, Lisa M., Harris, Peter C., Hoefele, Julia, Hung, Adriana M., Knoers, Nine V.A.M., Kopp, Jeffrey B., Kretzler, Matthias, Lanktree, Matthew B., Lipska-Ziętkiewicz, Beata S., Nicholls, Kathleen, Nozu, Kandai, Ojo, Akinlolu, Parsa, Afshin, Pattaro, Cristian, Pei, York, Pollak, Martin R., Rhee, Eugene P., Sanna-Cherchi, Simone, Savige, Judy, Sayer, John A., Scolari, Francesco, Sedor, John R., Sim, Xueling, Somlo, Stefan, Susztak, Katalin, Tayo, Bamidele O., Torra, Roser, van Eerde, Albertien M., Weinstock, André, Winkler, Cheryl A., Wuttke, Matthias, Zhang, Hong, King, Jennifer M., Cheung, Michael, Jadoul, Michel, Winkelmayer, Wolfgang C., Gharavi, Ali G.
Published in Kidney international

Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

by Chintalapudi, Sumana R, Maria, Doaa, Di Wang, Xiang, Bailey, Jessica N Cooke, Hysi, Pirro G, Wiggs, Janey L, Williams, Robert W, Jablonski, Monica M
Published in Nature communications