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Search Results - Therkelsen, Carly A
Search Results - Therkelsen, Carly A
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Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor
by
Daigle, Scott R.
,
Olhava, Edward J.
,
Therkelsen, Carly A.
,
Majer, Christina R.
,
Sneeringer, Christopher J.
,
Song, Jeffrey
,
Johnston, L. Danielle
,
Scott, Margaret Porter
,
Smith, Jesse J.
,
Xiao, Yonghong
,
Jin, Lei
,
Kuntz, Kevin W.
,
Chesworth, Richard
,
Moyer, Mikel P.
,
Bernt, Kathrin M.
,
Tseng, Jen-Chieh
,
Kung, Andrew L.
,
Armstrong, Scott A.
,
Copeland, Robert A.
,
Richon, Victoria M.
,
Pollock, Roy M.
Published in
Cancer cell
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Potent inhibition of DOT1L as treatment of MLL-fusion leukemia
by
Daigle, Scott R.
,
Olhava, Edward J.
,
Therkelsen, Carly A.
,
Basavapathruni, Aravind
,
Jin, Lei
,
Boriack-Sjodin, P. Ann
,
Allain, Christina J.
,
Klaus, Christine R.
,
Raimondi, Alejandra
,
Scott, Margaret Porter
,
Waters, Nigel J.
,
Chesworth, Richard
,
Moyer, Mikel P.
,
Copeland, Robert A.
,
Richon, Victoria M.
,
Pollock, Roy M.
Published in
Blood
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Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L
by
Basavapathruni, Aravind
,
Jin, Lei
,
Daigle, Scott R.
,
Majer, Christina R. A.
,
Therkelsen, Carly A.
,
Wigle, Tim J.
,
Kuntz, Kevin W.
,
Chesworth, Richard
,
Pollock, Roy M.
,
Scott, Margaret P.
,
Moyer, Mikel P.
,
Richon, Victoria M.
,
Copeland, Robert A.
,
Olhava, Edward J.
Published in
Chemical biology & drug design
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Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitor
by
Basavapathruni, Aravind
,
Olhava, Edward J.
,
Daigle, Scott R.
,
Therkelsen, Carly A.
,
Jin, Lei
,
Boriack-Sjodin, P. Ann
,
Allain, Christina J.
,
Klaus, Christine R.
,
Raimondi, Alejandra
,
Scott, Margaret Porter
,
Dovletoglou, Angelos
,
Richon, Victoria M.
,
Pollock, Roy M.
,
Copeland, Robert A.
,
Moyer, Mikel P.
,
Chesworth, Richard
,
Pearson, Paul G.
,
Waters, Nigel J.
Published in
Biopharmaceutics & drug disposition
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DOT1L Inhibitor EPZ-5676 Displays Synergistic Antiproliferative Activity in Combination with Standard of Care Drugs or DNA Hypomethylating Agents in MLL-Rearranged Leukemia Cells
by
Klaus, Christine R
,
Daigle, Scott R.
,
Iwanowics, Dorothy
,
Johnston, L. Danielle
,
Therkelsen, Carly A
,
Smith, Jesse J
,
Moyer, Mikel P
,
Copeland, Robert A.
,
Olhava, Edward J
,
Scott, Margaret Porter
,
Pollock, Roy M.
,
Raimondi, Alejandra
Published in
Blood
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Preclinical Characterization of a Potent, Selective Inhibitor of the Protein Methyltransferase DOT1L for Use in the Treatment of MLL-Rearranged Leukemia
by
Pollock, Roy M
,
Daigle, Scott R
,
Therkelsen, Carly A
,
Basavapathruni, Aravind
,
Jin, Lei
,
Allain, Christina J
,
Klaus, Christine R
,
Raimondi, Alejandra
,
Scott, Margaret Porter
,
Chesworth, Richard
,
Moyer, Mikel P
,
Copeland, Robert A
,
Richon, Victoria M
,
Olhava, Edward J
Published in
Blood
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Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor
by
Pollock, Roy M
,
Daigle, Scott R
,
Olhava, Edward J
,
Therkelsen, Carly A
,
Majer, Christina R
,
Song, Jeffrey
,
Allain, Christina J
,
Sneeringer, Christopher J
,
Johnston, L. Danielle
,
Scott, Margaret Porter
,
Jin, Lei
,
Kuntz, Kevin W
,
Chesworth, Richard
,
Moyer, Mikel P
,
Bernt, Kathrin M
,
Armstrong, Scott
,
Copeland, Robert A
,
Richon, Victoria M
Published in
Blood
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