Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through Analysis of Viral Genomics and Structure

by Rando, Halie M, MacLean, Adam L, Lee, Alexandra J, Lordan, Ronan, Ray, Sandipan, Bansal, Vikas, Skelly, Ashwin N, Sell, Elizabeth, Dziak, John J, Shinholster, Lamonica, D'Agostino McGowan, Lucy, Ben Guebila, Marouen, Wellhausen, Nils, Knyazev, Sergey, Boca, Simina M, Capone, Stephen, Qi, Yanjun, Park, YoSon, Mai, David, Sun, Yuchen, Boerckel, Joel D, Brueffer, Christian, Byrd, James Brian, Kamil, Jeremy P, Wang, Jinhui, Velazquez, Ryan, Szeto, Gregory L, Barton, John P, Goel, Rishi Raj, Mangul, Serghei, Lubiana, Tiago, Gitter, Anthony, Greene, Casey S
Published in mSystems

Identification and Development of Therapeutics for COVID-19

by Rando, Halie M, Wellhausen, Nils, Ghosh, Soumita, Lee, Alexandra J, Dattoli, Anna Ada, Hu, Fengling, Byrd, James Brian, Rafizadeh, Diane N, Lordan, Ronan, Qi, Yanjun, Sun, Yuchen, Brueffer, Christian, Field, Jeffrey M, Ben Guebila, Marouen, Jadavji, Nafisa M, Skelly, Ashwin N, Ramsundar, Bharath, Wang, Jinhui, Goel, Rishi Raj, Park, YoSon, Boca, Simina M, Gitter, Anthony, Greene, Casey S
Published in mSystems

Genome-wide Association Study Identifies Loci at ATF7IP and KLK2 Associated with Percentage of Circulating Free PSA

by Jin, Guangfu, Zheng, Siqun Lilly, Lilja, Hans, Kim, Seong-Tae, Tao, Sha, Gao, Zhengrong, Young, Tracey, Wiklund, Fredrik, Feng, Junjie, Isaacs, William B, Rittmaster, Roger S, Gronberg, Henrik, Condreay, Lynn D, Sun, Jielin, Xu, Jianfeng
Published in Neoplasia (New York, N.Y.)

Enhanced rate of cleavage at Arg306 and Arg506 in coagulation factor Va by Gla domain-mutated human activated protein C

by Sun, Yong-Hui L., Tran, Sinh, Norström, Eva, Dahlbäck, Björn
Published in The Journal of biological chemistry

A saturated map of common genetic variants associated with human height

by Yengo, Loïc, Karaderi, Tugce, Vrieze, Scott, Alvarez, Marcus, Arbeeva, Liubov, Bhaskar, Seema, Brody, Jennifer A, Burgdorf, Kristoffer S, Cai, Qiuyin, Chang, Li-Ching, Couture, Christian, Dietl, Alexander, Giannakopoulou, Olga, Gjesing, Anette P, Havulinna, Aki S, Hindy, George, Johansson, Ingegerd, Jørgensen, Torben, Kanoni, Stavroula, Kim, Han-Na, Le, Phuong, Lin, Shih-Yi, Liu, Jun, Long, Jirong, Mavarani, Laven, Nakatochi, Masahiro, Nethander, Maria, Pandit, Anita, Christofidou, Paraskevi, Pyarajan, Saiju, Rakugi, Hiromi, Rasheed, Asif, Raven, Dennis, Riveros, Carlos, Sendamarai, Anoop, Sitlani, Colleen M, Taylor, Kent D, Tayo, Bamidele O, Theusch, Elizabeth, Vaccargiu, Simona, van der Laan, Sander W, Verma, Shefali S, Veturi, Yogasudha, Wang, Chaolong, Bin Wei, Wen, Wu, Yang, Xia, Rui, Zimmermann, Martina E, Zoledziewska, Magdalena, Åsvold, Bjørn Olav, Biino, Ginevra, Boomsma, Dorret I, Brumpton, Ben, Chambers, John C, Ciullo, Marina, Janaka de Silva, H, Dedoussis, George V, Feitosa, Mary F, Ford, Ian, Hewitt, Alex W, Huang, Paul L, Jukema, J Wouter, Kang, Kui Dong, Kessler, Thorsten, Koh, Woon-Puay, Lieb, Wolfgang, Lye, Stephen J, McGarrah, Robert W, Mellström, Dan, Mucci, Lorelei A, Orozco, Lorena, Qu, Jia, Rader, Daniel J, Rallidis, Loukianos S, Rao, Dabeeru C, Rhee, Sang Youl, Rudan, Igor, Schmidt, Börge, Schmidt, Helena, Schulze, Matthias B, Simonsick, Eleanor M, Singleton, Andrew B, Stampfer, Meir J, 't Hart, Leen M, Timpson, Nicholas J, Tremblay, Angelo, Tusié-Luna, Maria-Teresa, van der Harst, Pim, van Schoor, Natasja M, Widen, Elisabeth, Willemsen, Gonneke, Willett, Walter C, Wilson, James F, Yuan, Jian-Min, Zhu, Xiaofeng, O'Donnell, Christopher J, Sun, Yan V, Justice, Anne E, Winkler, Thomas W, Willer, Cristen J
Published in Nature (London)

HLA and KIR Associations of Cervical Neoplasia

by Bao, Xiao, Hanson, Aimee L, Madeleine, Margaret M, Wang, Sophia S, Schwartz, Stephen M, Newell, Felicity, Pettersson-Kymmer, Ulrika, Hemminki, Kari, Tiews, Sven, Steinberg, Winfried, Rader, Janet S, Castro, Felipe, Safaeian, Mahboobeh, Franco, Eduardo L, Coutlée, François, Ohlsson, Claes, Cortes, Adrian, Marshall, Mhairi, Mukhopadhyay, Pamela, Cremin, Katie, Johnson, Lisa G, Garland, Suzanne M, Tabrizi, Sepehr N, Wentzensen, Nicolas, Sitas, Freddy, Trimble, Cornelia, Little, Julian, Cruickshank, Maggie, Frazer, Ian H, Hildesheim, Allan, Brown, Matthew A, Duncan, Emma L, Sun, Ying Pu, Leo, Paul J
Published in The Journal of infectious diseases

Population health status in China: EQ-5D results, by age, sex and socio-economic status, from the National Health Services Survey 2008

by Sun, Sun, Chen, Jiaying, Johannesson, Magnus, Kind, Paul, Xu, Ling, Zhang, Yaoguang, Burström, Kristina
Published in Quality of life research

Design, structure and plasma binding of ancestral β-CoV scaffold antigens

by Hueting, David, Schriever, Karen, Sun, Rui, Vlachiotis, Stelios, Zuo, Fanglei, Du, Likun, Persson, Helena, Hofström, Camilla, Ohlin, Mats, Walldén, Karin, Buggert, Marcus, Hammarström, Lennart, Marcotte, Harold, Pan-Hammarström, Qiang, Andréll, Juni, Syrén, Per-Olof
Published in Nature communications

Meta-analysis of Genome-wide Association Studies Identifies 1q22 as a Susceptibility Locus for Intracerebral Hemorrhage

by Woo, Daniel, Falcone, Guido J., Devan, William J., Brown, W. Mark, Biffi, Alessandro, Howard, Timothy D., Anderson, Christopher D., Brouwers, H. Bart, Valant, Valerie, Battey, Thomas W.K., Radmanesh, Farid, Raffeld, Miriam R., Baedorf-Kassis, Sylvia, Deka, Ranjan, Woo, Jessica G., Martin, Lisa J., Haverbusch, Mary, Moomaw, Charles J., Sun, Guangyun, Broderick, Joseph P., Flaherty, Matthew L., Martini, Sharyl R., Kleindorfer, Dawn O., Kissela, Brett, Comeau, Mary E., Jagiella, Jeremiasz M., Schmidt, Helena, Freudenberger, Paul, Pichler, Alexander, Enzinger, Christian, Hansen, Björn M., Norrving, Bo, Jimenez-Conde, Jordi, Giralt-Steinhauer, Eva, Elosua, Roberto, Cuadrado-Godia, Elisa, Soriano, Carolina, Roquer, Jaume, Kraft, Peter, Ayres, Alison M., Schwab, Kristin, McCauley, Jacob L., Pera, Joanna, Urbanik, Andrzej, Rost, Natalia S., Goldstein, Joshua N., Viswanathan, Anand, Stögerer, Eva-Maria, Tirschwell, David L., Selim, Magdy, Brown, Devin L., Silliman, Scott L., Worrall, Bradford B., Meschia, James F., Kidwell, Chelsea S., Montaner, Joan, Fernandez-Cadenas, Israel, Delgado, Pilar, Malik, Rainer, Dichgans, Martin, Greenberg, Steven M., Rothwell, Peter M., Lindgren, Arne, Slowik, Agnieszka, Schmidt, Reinhold, Langefeld, Carl D., Rosand, Jonathan
Published in American journal of human genetics

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

by Di Cesare, Mariachiara, Danaei, Goodarz, Bilano, Ver, Bovet, Pascal, Mondo, Charles K, Neuhauser, Hannelore K, Sundström, Johan, Smeeth, Liam, Ezzati, Majid, Acosta-Cazares, Benjamin, Agyemang, Charles, Al Raddadi, Rajaa, Al Woyatan, Rihab, Ängquist, Lars, Ariansen, Inger, Banegas, José R, Batieha, Anwar M, Bernabe-Ortiz, Antonio, Blokstra, Anneke, Bobak, Martin, Brajkovich, Imperia, Cardoso, Viviane C, Caserta, Carmelo A, Chamukuttan, Snehalatha, Chen, Shuohua, Chetrit, Angela, Clays, Els, Cooper, Cyrus, Dehghan, Abbas, Dhana, Klodian, Dulskiene, Virginija, Elosua, Roberto, Faeh, David, Farzadfar, Farshad, Franco, Oscar H, Frontera, Guillermo, Furusawa, Takuro, Geleijnse, Johanna M, Gianfagna, Francesco, Grøntved, Anders, Gurzkowska, Beata, Houti, Leila, Hu, Yonghua, Husseini, Abdullatif S, Kafatos, Anthony, Kauhanen, Jussi, Kaur, Prabhdeep, Kemper, Han C G, Khalili, Davood, Khang, Young-Ho, Le, Tuyen D, Lekhraj, Rampal, Luksiene, Dalia, Manios, Yannis, Marrugat, Jaume, Matijasevich, Alicia, Posso, Anselmo J Mc Donald, McFarlane, Shelly R, Menon, Geetha R, Møller, Niels C, Molnár, Dénes, Momenan, Amirabbas, Moreno, Luis A, Mostafa, Aya, Mota, Jorge, Navarrete-Muñoz, Eva Maria, Noto, Davide, Parnell, Winsome R, Peixoto, Sergio Viana, Pelletier, Catherine, Pereira, Alexandre C, Pilotto, Lorenza, Plans-Rubió, Pedro, Porta, Miquel, Riboli, Elio, Rigo, Fernando, Robinson, Sian M, Rubinstein, Adolfo, Salonen, Jukka T, Salvetti, Massimo, Sans, Susana, Saramies, Jouko L, Schargrodsky, Herman, Sibai, Abla M, Slusarczyk, Przemyslaw, So, Hung-Kwan, Solfrizzi, Vincenzo, Song, Yi, Sørensen, Thorkild IA, Tang, Line, Tao, Yong, Topbas, Murat, Trichopoulou, Antonia, Veronesi, Giovanni, Vrdoljak, Ana, Wojtyniak, Bogdan, Wu, Frederick C, Yusoff, Ahmad F, Yusoff, Muhammad Fadhli M, Zheng, Yingffeng
Published in The Lancet (British edition)

A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia

by Chen, Xu, Gustafsson, Stefan, Whitington, Thomas, Borné, Yan, Lorentzen, Erik, Sun, Jitong, Almgren, Peter, Su, Jun, Karlsson, Robert, Song, Jie, Lu, Yi, Zhan, Yiqiang, Hägg, Sara, Svensson, Per, Smedby, Karin E, Slager, Susan L, Ingelsson, Erik, Lindgren, Cecilia M, Morris, Andrew P, Melander, Olle, Karlsson, Thomas, de Faire, Ulf, Caidahl, Kenneth, Engström, Gunnar, Lind, Lars, Karlsson, Mikael C I, Pedersen, Nancy L, Frostegård, Johan, Magnusson, Patrik K E
Published in Human molecular genetics

Swedish experience-based value sets for EQ-5D health states

by Burström, Kristina, Sun, Sun, Gerdtham, Ulf-G, Henriksson, Martin, Johannesson, Magnus, Levin, Lars-Åke, Zethraeus, Niklas
Published in Quality of life research

Vorinostat in patients with advanced malignant pleural mesothelioma who have progressed on previous chemotherapy (VANTAGE-014): a phase 3, double-blind, randomised, placebo-control...

by Krug, Lee M, Dr, Kindler, Hedy L, Prof, Calvert, Hilary, MD, Manegold, Christian, Prof, Tsao, Anne S, MD, Fennell, Dean, Prof, Öhman, Ronny, MD, Plummer, Ruth, Prof, Eberhardt, Wilfried E E, MD, Fukuoka, Kazuya, MD, Gaafar, Rabab M, Prof, Lafitte, Jean-Jacques, Prof, Hillerdal, Gunnar, MD, Chu, Quincy, MD, Buikhuisen, Wieneke A, MD, Lubiniecki, Gregory M, MD, Sun, Xing, PhD, Smith, Margaret, BA, Baas, Paul, Prof
Published in The lancet oncology

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

by Imai, Yumiko, Kuba, Keiji, Neely, G. Greg, Yaghubian-Malhami, Rubina, Perkmann, Thomas, van Loo, Geert, Ermolaeva, Maria, Veldhuizen, Ruud, Leung, Y.H. Connie, Wang, Hongliang, Liu, Haolin, Sun, Yang, Pasparakis, Manolis, Kopf, Manfred, Mech, Christin, Bavari, Sina, Peiris, J.S. Malik, Slutsky, Arthur S., Akira, Shizuo, Hultqvist, Malin, Holmdahl, Rikard, Nicholls, John, Jiang, Chengyu, Binder, Christoph J., Penninger, Josef M.
Published in Cell

Alcohol Screening and Risk of Postoperative Complications in Male VA Patients Undergoing Major Non-cardiac Surgery

by Bradley, Katharine A., Rubinsky, Anna D., Sun, Haili, Bryson, Chris L., Bishop, Michael J., Blough, David K., Henderson, William G., Maynard, Charles, Hawn, Mary T., Tønnesen, Hanne, Hughes, Grant, Beste, Lauren A., Harris, Alex H. S., Hawkins, Eric J., Houston, Thomas K., Kivlahan, Daniel R.
Published in Journal of general internal medicine : JGIM

Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk

by Forteza, Maria J, Berg, Martin, Edsfeldt, Andreas, Sun, Jangming, Baumgartner, Roland, Kareinen, Ilona, Casagrande, Felipe Beccaria, Hedin, Ulf, Zhang, Song, Vuckovic, Ivan, Dzeja, Petras P, Polyzos, Konstantinos A, Gisterå, Anton, Trauelsen, Mette, Schwartz, Thue W, Dib, Lea, Herrmann, Joerg, Monaco, Claudia, Matic, Ljubica, Gonçalves, Isabel, Ketelhuth, Daniel F J
Published in Cardiovascular research

FcγRIIIa receptor interacts with androgen receptor and PIP5K1α to promote growth and metastasis of prostate cancer

by Larsson, Per Flodbring, Karlsson, Richard, Sarwar, Martuza, Miftakhova, Regina, Wang, Tianyan, Syed Khaja, Azharuddin Sajid, Semenas, Julius, Chen, Sa, Hedblom, Andreas, Ali, Amjad, Ekström‐Holka, Kristina, Simoulis, Athanasios, Kumar, Anjani, Wingren, Anette Gjörloff, Robinson, Brian, Nyunt Wai, Sun, Mongan, Nigel P., Heery, David M., Öhlund, Daniel, Grundström, Thomas, Ødum, Niels, Persson, Jenny L.
Published in Molecular oncology

Skin mesenchymal niches maintain and protect AML-initiating stem cells

by Sandhow, Lakshmi, Cai, Huan, Leonard, Elory, Xiao, Pingnan, Tomaipitinca, Luana, Månsson, Alma, Kondo, Makoto, Sun, Xiaoyan, Johansson, Anne-Sofie, Tryggvason, Karl, Kasper, Maria, Järås, Marcus, Qian, Hong
Published in The Journal of experimental medicine

Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality

by Schunk, Stefan J, Kleber, Marcus E, März, Winfried, Pang, Shichao, Zewinger, Stephen, Triem, Sarah, Ege, Philipp, Reichert, Matthias C, Krawczyk, Marcin, Weber, Susanne N, Jaumann, Isabella, Schmit, David, Sarakpi, Tamim, Wagenpfeil, Stefan, Kramann, Rafael, Boerwinkle, Eric, Ballantyne, Christie M, Grove, Megan L, Tragante, Vinicius, Pilbrow, Anna P, Richards, A Mark, Cameron, Vicky A, Doughty, Robert N, Dubé, Marie-Pierre, Tardif, Jean-Claude, Feroz-Zada, Yassamin, Sun, Maxine, Liu, Chang, Ko, Yi-An, Quyyumi, Arshed A, Hartiala, Jaana A, Tang, W H Wilson, Hazen, Stanley L, Allayee, Hooman, McDonough, Caitrin W, Gong, Yan, Cooper-DeHoff, Rhonda M, Johnson, Julie A, Scholz, Markus, Teren, Andrej, Burkhardt, Ralph, Martinsson, Andreas, Smith, J Gustav, Wallentin, Lars, James, Stefan K, Eriksson, Niclas, White, Harvey, Held, Claes, Waterworth, Dawn, Trompet, Stella, Jukema, J Wouter, Ford, Ian, Stott, David J, Sattar, Naveed, Cresci, Sharon, Spertus, John A, Campbell, Hannah, Tierling, Sascha, Walter, Jörn, Ampofo, Emmanuel, Niemeyer, Barbara A, Lipp, Peter, Schunkert, Heribert, Böhm, Michael, Koenig, Wolfgang, Fliser, Danilo, Laufs, Ulrich, Speer, Thimoteus
Published in European heart journal

The Surgeon's Role in the Opioid Crisis: A Narrative Review and Call to Action

by Shadbolt, Cade, Abbott, J Haxby, Camacho, Ximena, Clarke, Philip, Lohmander, L Stefan, Spelman, Tim, Sun, Eric C, Thorlund, Jonas B, Zhang, Yuting, Dowsey, Michelle M, Choong, Peter F M
Published in Frontiers in surgery