A new paradigm for leprosy diagnosis based on host gene expression

by Leal-Calvo, Thyago, Avanzi, Charlotte, Mendes, Mayara Abud, Benjak, Andrej, Busso, Philippe, Pinheiro, Roberta Olmo, Sarno, Euzenir Nunes, Cole, Stewart Thomas, Moraes, Milton Ozório
Published in PLoS pathogens

Gene expression patterns associated with multidrug therapy in multibacillary leprosy

by Ferreira, Helen, Leal-Calvo, Thyago, Mendes, Mayara Abud, Avanzi, Charlotte, Busso, Philippe, Benjak, Andrej, Sales, Anna Maria, Ferreira, Cássio Porto, de Berrêdo-Pinho, Márcia, Cole, Stewart Thomas, Sarno, Euzenir Nunes, Moraes, Milton Ozório, Pinheiro, Roberta Olmo
Published in Frontiers in cellular and infection microbiology

A new paradigm for leprosy diagnosis based on host gene expression

by Thyago Leal-Calvo, Charlotte Avanzi, Mayara Abud Mendes, Andrej Benjak, Philippe Busso, Roberta Olmo Pinheiro, Euzenir Nunes Sarno, Stewart Thomas Cole, Milton Ozório Moraes
Published in PLoS pathogens

Emergence of Mycobacterium leprae Rifampin Resistance Evaluated by Whole-Genome Sequencing after 48 Years of Irregular Treatment

by Avanzi, Charlotte, Maia, Raquel Cristina, Benjak, Andrej, Nery, José Augusto, Sales, Anna Maria, Miranda, Alice, Duppre, Nadia Cristina, Nogueira Brum Fontes, Amanda, Pereira da Silva, Tatiana, Olmo Pinheiro, Roberta, Neves-Manta, Fernanda, Moreira, Suelen Justo Maria, Busso, Philippe, Sarno, Euzenir Nunes, Suffys, Phillip Noel, Cole, Stewart Thomas, Moraes, Milton Ozório
Published in Antimicrobial agents and chemotherapy

Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis

by Huynh, Tien-Phat V., Liao, Fan, Francis, Caroline M., Robinson, Grace O., Serrano, Javier Remolina, Jiang, Hong, Roh, Joseph, Finn, Mary Beth, Sullivan, Patrick M., Esparza, Thomas J., Stewart, Floy R., Mahan, Thomas E., Ulrich, Jason D., Cole, Tracy, Holtzman, David M.
Published in Neuron (Cambridge, Mass.)

Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous Infection

by Hall, Victoria, Foulkes, Sarah, Insalata, Ferdinando, Kirwan, Peter, Saei, Ayoub, Atti, Ana, Wellington, Edgar, Khawam, Jameel, Munro, Katie, Cole, Michelle, Tranquillini, Caio, Taylor-Kerr, Andrew, Hettiarachchi, Nipunadi, Calbraith, Davina, Sajedi, Noshin, Milligan, Iain, Themistocleous, Yrene, Corrigan, Diane, Cromey, Lisa, Price, Lesley, Stewart, Sally, de Lacy, Elen, Norman, Chris, Linley, Ezra, Otter, Ashley D, Semper, Amanda, Hewson, Jacqueline, Silvia D’Arcangelo, Chand, Meera, Brown, Colin S, Brooks, Tim, Islam, Jasmin, Charlett, Andre, Hopkins, Susan
Published in New England Journal of Medicine

Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study

by Swann, Olivia V, Holden, Karl A, Turtle, Lance, Pollock, Louisa, Fairfield, Cameron J, Drake, Thomas M, Seth, Sohan, Egan, Conor, Hardwick, Hayley E, Halpin, Sophie, Girvan, Michelle, Donohue, Chloe, Pritchard, Mark, Patel, Latifa B, Ladhani, Shamez, Sigfrid, Louise, Sinha, Ian P, Olliaro, Piero L, Nguyen-Van-Tam, Jonathan S, Horby, Peter W, Merson, Laura, Carson, Gail, Dunning, Jake, Openshaw, Peter J M, Baillie, J Kenneth, Harrison, Ewen M, Docherty, Annemarie B, Semple, Malcolm G
Published in BMJ

Volcanic ash impacts on critical infrastructure

by Wilson, Thomas M., Stewart, Carol, Sword-Daniels, Victoria, Leonard, Graham S., Johnston, David M., Cole, Jim W., Wardman, Johnny, Wilson, Grant, Barnard, Scott T.
Published in Physics and chemistry of the earth. Parts A/B/C

Genome-Wide Comparison of Medieval and Modern Mycobacterium leprae

by Schuenemann, Verena J., Singh, Pushpendra, Mendum, Thomas A., Krause-Kyora, Ben, Jäger, Günter, Bos, Kirsten I., Herbig, Alexander, Economou, Christos, Benjak, Andrej, Busso, Philippe, Nebel, Almut, Boldsen, Jesper L., Kjellström, Anna, Wu, Huihai, Stewart, Graham R., Taylor, G. Michael, Bauer, Peter, Lee, Oona Y.-C., Wu, Houdini H. T., Minnikin, David E., Besra, Gurdyal S., Tucker, Katie, Roffey, Simon, Sow, Samba O., Cole, Stewart T., Nieselt, Kay, Krause, Johannes
Published in Science (American Association for the Advancement of Science)

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score

by Knight, Stephen R, Ho, Antonia, Pius, Riinu, Buchan, Iain, Carson, Gail, Drake, Thomas M, Dunning, Jake, Fairfield, Cameron J, Gamble, Carrol, Green, Christopher A, Gupta, Rishi, Halpin, Sophie, Hardwick, Hayley E, Holden, Karl A, Horby, Peter W, Jackson, Clare, Mclean, Kenneth A, Merson, Laura, Nguyen-Van-Tam, Jonathan S, Norman, Lisa, Noursadeghi, Mahdad, Olliaro, Piero L, Pritchard, Mark G, Russell, Clark D, Shaw, Catherine A, Sheikh, Aziz, Solomon, Tom, Sudlow, Cathie, Swann, Olivia V, Turtle, Lance CW, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G, Docherty, Annemarie B, Harrison, Ewen M
Published in BMJ

High-resolution detection of DNA binding sites of the global transcriptional regulator GlxR in Corynebacterium glutamicum

by Jungwirth, Britta, Sala, Claudia, Kohl, Thomas A, Uplekar, Swapna, Baumbach, Jan, Cole, Stewart T, Pühler, Alfred, Tauch, Andreas
Published in Microbiology (Society for General Microbiology)

Machine Learning Models for Mycobacterium tuberculosis In Vitro Activity: Prediction and Target Visualization

by Lane, Thomas R., Urbina, Fabio, Rank, Laura, Gerlach, Jacob, Riabova, Olga, Lepioshkin, Alexander, Kazakova, Elena, Vocat, Anthony, Tkachenko, Valery, Cole, Stewart, Makarov, Vadim, Ekins, Sean
Published in Molecular pharmaceutics

Out-of-Hospital Hypertonic Resuscitation Following Severe Traumatic Brain Injury: A Randomized Controlled Trial

by Bulger, Eileen M, May, Susanne, Brasel, Karen J, Schreiber, Martin, Kerby, Jeffrey D, Tisherman, Samuel A, Newgard, Craig, Slutsky, Arthur, Coimbra, Raul, Emerson, Scott, Minei, Joseph P, Bardarson, Berit, Kudenchuk, Peter, Baker, Andrew, Christenson, Jim, Idris, Ahamed, Davis, Daniel, Fabian, Timothy C, Aufderheide, Tom P, Callaway, Clifton, Williams, Carolyn, Banek, Jane, Vaillancourt, Christian, van Heest, Rardi, Sopko, George, Hata, J. Steven, Hoyt, David B, ROC Investigators, for the
Published in JAMA : the journal of the American Medical Association

A central role for dityrosine crosslinking of Amyloid-β in Alzheimer's disease

by Al-Hilaly, Youssra K, Williams, Thomas L, Stewart-Parker, Maris, Ford, Lenzie, Skaria, Eldhose, Cole, Michael, Bucher, William Grant, Morris, Kyle L, Sada, Alaa Abdul, Thorpe, Julian R, Serpell, Louise C
Published in Acta neuropathologica communications

Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease. An International Multicenter Study

by Drake, Thomas M, Docherty, Annemarie B, Harrison, Ewen M, Quint, Jennifer K, Adamali, Huzaifa, Agnew, Sarah, Babu, Suresh, Barber, Christopher M, Barratt, Shaney, Bendstrup, Elisabeth, Bianchi, Stephen, Villegas, Diego Castillo, Chaudhuri, Nazia, Chua, Felix, Coker, Robina, Chang, William, Crawshaw, Anjali, Crowley, Louise E, Dosanjh, Davinder, Fiddler, Christine A, Forrest, Ian A, George, Peter M, Gibbons, Michael A, Groom, Katherine, Haney, Sarah, Hart, Simon P, Heiden, Emily, Henry, Michael, Ho, Ling-Pei, Hoyles, Rachel K, Hutchinson, John, Hurley, Killian, Jones, Mark, Jones, Steve, Kokosi, Maria, Kreuter, Michael, MacKay, Laura S, Mahendran, Siva, Margaritopoulos, George, Molina-Molina, Maria, Molyneaux, Philip L, O'Brien, Aiden, O'Reilly, Katherine, Packham, Alice, Parfrey, Helen, Poletti, Venerino, Porter, Joanna C, Renzoni, Elisabetta, Rivera-Ortega, Pilar, Russell, Anne-Marie, Saini, Gauri, Spencer, Lisa G, Stella, Giulia M, Stone, Helen, Sturney, Sharon, Thickett, David, Thillai, Muhunthan, Wallis, Tim, Ward, Katie, Wells, Athol U, West, Alex, Wickremasinghe, Melissa, Woodhead, Felix, Hearson, Glenn, Howard, Lucy, Baillie, J Kenneth, Openshaw, Peter J M, Semple, Malcolm G, Stewart, Iain, Jenkins, R Gisli
Published in American journal of respiratory and critical care medicine

Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group

by Gottardo, Nicholas G., Hansford, Jordan R., McGlade, Jacqueline P., Alvaro, Frank, Ashley, David M., Bailey, Simon, Baker, David L., Bourdeaut, Franck, Cho, Yoon-Jae, Clay, Moira, Clifford, Steven C., Cohn, Richard J., Cole, Catherine H., Dallas, Peter B., Downie, Peter, Doz, François, Ellison, David W., Endersby, Raelene, Fisher, Paul G., Hassall, Timothy, Heath, John A., Hii, Hilary L., Jones, David T. W., Junckerstorff, Reimar, Kellie, Stewart, Kool, Marcel, Kotecha, Rishi S., Lichter, Peter, Laughton, Stephen J., Lee, Sharon, McCowage, Geoff, Northcott, Paul A., Olson, James M., Packer, Roger J., Pfister, Stefan M., Pietsch, Torsten, Pizer, Barry, Pomeroy, Scott L., Remke, Marc, Robinson, Giles W., Rutkowski, Stefan, Schoep, Tobias, Shelat, Anang A., Stewart, Clinton F., Sullivan, Michael, Taylor, Michael D., Wainwright, Brandon, Walwyn, Thomas, Weiss, William A., Williamson, Dan, Gajjar, Amar
Published in Acta neuropathologica

Calnexin Induces Expansion of Antigen-Specific CD4+ T Cells that Confer Immunity to Fungal Ascomycetes via Conserved Epitopes

by Wüthrich, Marcel, Brandhorst, Tristan T., Sullivan, Thomas D., Filutowicz, Hanna, Sterkel, Alana, Stewart, Douglas, Li, Mengyi, Lerksuthirat, Tassanee, LeBert, Vanessa, Shen, Zu Ting, Ostroff, Gary, Deepe, George S., Hung, Chiung Yu, Cole, Garry, Walter, Jennifer A., Jenkins, Marc K., Klein, Bruce
Published in Cell host & microbe

Synthesis of functionalized primary alkyltrifluoroborates via hydroboration and elimination of auxiliary groups using benzoquinone reductive alkylation

by Zillman, David J., Sami, Reman A., Daley, Lauren M., Polk, Stewart C., Hincapié, Gloria C., Cole, Thomas E.
Published in Journal of organometallic chemistry

Low-Dose Dopamine or Low-Dose Nesiritide in Acute Heart Failure With Renal Dysfunction: The ROSE Acute Heart Failure Randomized Trial

by Chen, Horng H, Anstrom, Kevin J, Givertz, Michael M, Stevenson, Lynne W, Semigran, Marc J, Goldsmith, Steven R, Bart, Bradley A, Bull, David A, Stehlik, Josef, LeWinter, Martin M, Konstam, Marvin A, Huggins, Gordon S, Rouleau, Jean L, O'Meara, Eileen, Tang, W. H. Wilson, Starling, Randall C, Butler, Javed, Deswal, Anita, Felker, G. Michael, O'Connor, Christopher M, Bonita, Raphael E, Margulies, Kenneth B, Cappola, Thomas P, Ofili, Elizabeth O, Mann, Douglas L, Dávila-Román, Víctor G, McNulty, Steven E, Borlaug, Barry A, Velazquez, Eric J, Lee, Kerry L, Shah, Monica R, Hernandez, Adrian F, Braunwald, Eugene, Redfield, Margaret M
Published in JAMA : the journal of the American Medical Association

Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled, double-blind, phase 2...

by Khoo, Saye H, FitzGerald, Richard, Saunders, Geoffrey, Middleton, Calley, Ahmad, Shazaad, Edwards, Christopher J, Hadjiyiannakis, Dennis, Walker, Lauren, Lyon, Rebecca, Shaw, Victoria, Mozgunov, Pavel, Periselneris, Jimstan, Woods, Christie, Bullock, Katie, Hale, Colin, Reynolds, Helen, Downs, Nichola, Ewings, Sean, Buadi, Amanda, Cameron, David, Edwards, Thomas, Knox, Emma, Donovan-Banfield, I'ah, Greenhalf, William, Chiong, Justin, Lavelle-Langham, Lara, Jacobs, Michael, Northey, Josh, Painter, Wendy, Holman, Wayne, Lalloo, David G, Tetlow, Michelle, Hiscox, Julian A, Jaki, Thomas, Fletcher, Thomas, Griffiths, Gareth, Paton, Nicholas, Hayden, Fred, Darbyshire, Janet, Lucas, Amy, Lorch, Ulrika, Freedman, Andrew, Knight, Richard, Julious, Stevan, Byrne, Rachel, Cubas Atienzar, Ana, Jones, Jayne, Williams, Chris, Song, Anna, Dixon, Jan, Alexandersson, Anja, Hatchard, Parys, Tilt, Emma, Titman, Andrew, Doce Carracedo, Ale, Chandran Gorner, Vatsi, Davies, Andrea, Woodhouse, Louis, Carlucci, Nicola, Okenyi, Emmanuel, Bula, Marcin, Dodd, Kate, Gibney, Jennifer, Dry, Lesley, Rashid Gardner, Zalina, Sammour, Amin, Cole, Christine, Rowland, Tim, Tsakiroglu, Maria, Yip, Vincent, Osanlou, Rostam, Stewart, Anna, Parker, Ben, Turgut, Tolga, Ahmed, Afshan, Starkey, Kay, Subin, Sujamole, Stockdale, Jennifer, Herring, Lisa, Baker, Jonathon, Oliver, Abigail, Pacurar, Mihaela, Owens, Dan, Munro, Alistair, Babbage, Gavin, Faust, Saul, Harvey, Matthew, Pratt, Danny, Nagra, Deepak, Vyas, Aashish
Published in The Lancet infectious diseases