Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis

by Codo, Ana Campos, Davanzo, Gustavo Gastão, Monteiro, Lauar de Brito, de Souza, Gabriela Fabiano, Muraro, Stéfanie Primon, Virgilio-da-Silva, João Victor, Prodonoff, Juliana Silveira, Carregari, Victor Corasolla, de Biagi Junior, Carlos Alberto Oliveira, Crunfli, Fernanda, Jimenez Restrepo, Jeffersson Leandro, Vendramini, Pedro Henrique, Reis-de-Oliveira, Guilherme, Bispo dos Santos, Karina, Toledo-Teixeira, Daniel A., Parise, Pierina Lorencini, Martini, Matheus Cavalheiro, Marques, Rafael Elias, Carmo, Helison R., Borin, Alexandre, Coimbra, Laís Durço, Boldrini, Vinícius O., Brunetti, Natalia S., Vieira, Andre S., Mansour, Eli, Ulaf, Raisa G., Bernardes, Ana F., Nunes, Thyago A., Ribeiro, Luciana C., Palma, Andre C., Agrela, Marcus V., Moretti, Maria Luiza, Sposito, Andrei C., Pereira, Fabrício Bíscaro, Velloso, Licio Augusto, Vinolo, Marco Aurélio Ramirez, Damasio, André, Proença-Módena, José Luiz, Carvalho, Robson Francisco, Mori, Marcelo A., Martins-de-Souza, Daniel, Nakaya, Helder I., Farias, Alessandro S., Moraes-Vieira, Pedro M.
Published in Cell Metabolism

Inflammation markers in the saliva of infants born from Zika-infected mothers: exploring potential mechanisms of microcephaly during fetal development

by de Oliveira, Diogo N, Lima, Estela O, Melo, Carlos F O R, Delafiori, Jeany, Guerreiro, Tatiane M, Rodrigues, Rafael G M, Morishita, Karen N, Silveira, Cynthia, Muraro, Stéfanie Primon, de Souza, Gabriela Fabiano, Vieira, Aline, Silva, Antônio, Batista, Rosângela F, Doriqui, Maria J R, Sousa, Patricia S, Milanez, Guilherme P, Proença-Módena, José L, Cavalcanti, Denise P, Catharino, Rodrigo R
Published in Scientific reports

Oropouche Virus Infects, Persists and Induces IFN Response in Human Peripheral Blood Mononuclear Cells as Identified by RNA PrimeFlow™ and qRT-PCR Assays

by Ribeiro Amorim, Mariene, Cornejo Pontelli, Marjorie, Fabiano de Souza, Gabriela, Primon Muraro, Stéfanie, de Toledo-Teixeira, Daniel Augusto, Forato, Julia, Bispo-Dos-Santos, Karina, Barbosa, Natália S, Cavalheiro Martini, Matheus, Lorencini Parise, Pierina, Vieira, Aline, Paier Milanez, Guilherme, Lamberti Pinto daSilva, Luis, Jaychand Lalwani, Pritesh, Santos Farias, Alessandro, Ramirez Vinolo, Marco Aurélio, Sesti-Costa, Renata, Arruda, Eurico, Proenca-Modena, Jose Luiz
Published in Viruses

PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease

by Duhalde Vega, Maite, Olivera, Daniela, Gastão Davanzo, Gustavo, Bertullo, Mauricio, Noya, Verónica, Fabiano de Souza, Gabriela, Primon Muraro, Stéfanie, Castro, Icaro, Arévalo, Ana Paula, Crispo, Martina, Galliussi, Germán, Russo, Sofía, Charbonnier, David, Rammauro, Florencia, Jeldres, Mathías, Alamón, Catalina, Varela, Valentina, Batthyany, Carlos, Bollati-Fogolín, Mariela, Oppezzo, Pablo, Pritsch, Otto, Proença-Módena, José Luiz, Nakaya, Helder I., Trias, Emiliano, Barbeito, Luis, Anegon, Ignacio, Cuturi, María Cristina, Moraes-Vieira, Pedro, Segovia, Mercedes, Hill, Marcelo
Published in Science advances

Kinetics of peripheral blood neutrophils in severe coronavirus disease 2019

by Metzemaekers, Mieke, Cambier, Seppe, Blanter, Marfa, Vandooren, Jennifer, Carvalho, Ana Carolina, Malengier‐Devlies, Bert, Vanderbeke, Lore, Jacobs, Cato, Coenen, Sofie, Martens, Erik, Pörtner, Noëmie, Vanbrabant, Lotte, Van Mol, Pierre, Van Herck, Yannick, Van Aerde, Nathalie, Hermans, Greet, Gunst, Jan, Borin, Alexandre, Toledo N Pereira, Bruna, SP Gomes, Arilson Bernardo, Primon Muraro, Stéfanie, Fabiano de Souza, Gabriela, S Farias, Alessandro, Proenca‐Modena, José Luiz, R Vinolo, Marco Aurélio, Marques, Pedro Elias, Wouters, Carine, Wauters, Els, Struyf, Sofie, Matthys, Patrick, Opdenakker, Ghislain, Marques, Rafael Elias, Wauters, Joost, Gouwy, Mieke, Proost, Paul, Wilmer, Alexander, Meersseman, Philippe, Lambrechts, Diether, Casaer, Michael, Rex, Steffen, Lorent, Nathalie, Thevissen, Karin, Martinod, Kim
Published in Clinical & Translational Immunology

Acid pH Increases SARS-CoV-2 Infection and the Risk of Death by COVID-19

by Jimenez, Leandro, Campos Codo, Ana, Sampaio, Vanderson de Souza, Oliveira, Antonio E. R., Ferreira, Lucas Kaoru Kobo, Davanzo, Gustavo Gastão, Brito Monteiro, Lauar de, Victor Virgilio-da-Silva, João, Borba, Mayla Gabriela Silva, Fabiano de Souza, Gabriela, Zini, Nathalia, Andrade Gandolfi, Flora de, Muraro, Stéfanie Primon, Luiz Proença-Modena, José, Val, Fernando Almeida, Cardoso Melo, Gisely, Monteiro, Wuelton Marcelo, Nogueira, Maurício Lacerda, Lacerda, Marcus Vinícius Guimarães, Moraes-Vieira, Pedro M., Nakaya, Helder I.
Published in Frontiers in medicine

Lung Inflammation Induced by Inactivated SARS-CoV-2 in C57BL/6 Female Mice Is Controlled by Intranasal Instillation of Vitamin D

by Fernandes de Souza, William Danilo, Zorzella-Pezavento, Sofia Fernanda Gonçalves, Ayupe, Marina Caçador, Salgado, Caio Loureiro, Oliveira, Bernardo de Castro, Moreira, Francielly, da Silva, Guilherme William, Muraro, Stefanie Primon, de Souza, Gabriela Fabiano, Proença-Módena, José Luiz, Araujo Junior, Joao Pessoa, Fonseca, Denise Morais da, Sartori, Alexandrina
Published in Cells (Basel, Switzerland)

Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis

by Codo, Ana Campos, Davanzo, Gustavo Gastão, Monteiro, Lauar de Brito, de Souza, Gabriela Fabiano, Muraro, Stéfanie Primon, Virgilio-da-Silva, João Victor, Prodonoff, Juliana Silveira, Carregari, Victor Corasolla, de Biagi Junior, Carlos Alberto Oliveira, Crunfli, Fernanda, Jimenez Restrepo, Jeffersson Leandro, Vendramini, Pedro Henrique, Reis-de-Oliveira, Guilherme, Bispo dos Santos, Karina, Toledo-Teixeira, Daniel A., Parise, Pierina Lorencini, Martini, Matheus Cavalheiro, Marques, Rafael Elias, Carmo, Helison R., Borin, Alexandre, Coimbra, Laís Durço, Boldrini, Vinícius O., Brunetti, Natalia S., Vieira, Andre S., Mansour, Eli, Ulaf, Raisa G., Bernardes, Ana F., Nunes, Thyago A., Ribeiro, Luciana C., Palma, Andre C., Agrela, Marcus V., Moretti, Maria Luiza, Sposito, Andrei C., Pereira, Fabrício Bíscaro, Velloso, Licio Augusto, Vinolo, Marco Aurélio Ramirez, Damasio, André, Proença-Módena, José Luiz, Carvalho, Robson Francisco, Mori, Marcelo A., Martins-de-Souza, Daniel, Nakaya, Helder I., Farias, Alessandro S., Moraes-Vieira, Pedro M.
Published in Cell metabolism

SARS-CoV-2 infects adipose tissue in a fat depot- and viral lineage-dependent manner

by Saccon, Tatiana Dandolini, Mousovich-Neto, Felippe, Ludwig, Raissa Guimarães, Carregari, Victor Corasolla, dos Anjos Souza, Ana Beatriz, dos Passos, Amanda Stephane Cruz, Martini, Matheus Cavalheiro, Barbosa, Priscilla Paschoal, de Souza, Gabriela Fabiano, Muraro, Stéfanie Primon, Forato, Julia, Amorim, Mariene Ribeiro, Marques, Rafael Elias, Veras, Flavio Protasio, Barreto, Ester, Gonçalves, Tiago Tomazini, Paiva, Isadora Marques, Fazolini, Narayana P. B., Onodera, Carolina Mie Kawagosi, Martins Junior, Ronaldo Bragança, de Araújo, Paulo Henrique Cavalcanti, Batah, Sabrina Setembre, Viana, Rosa Maria Mendes, de Melo, Danilo Machado, Fabro, Alexandre Todorovic, Arruda, Eurico, Queiroz Cunha, Fernando, Cunha, Thiago Mattar, Pretti, Marco Antônio M., Smith, Bradley Joseph, Marques-Souza, Henrique, Knittel, Thiago L., Ruiz, Gabriel Palermo, Profeta, Gerson S., Fontes-Cal, Tereza Cristina Minto, Boroni, Mariana, Vinolo, Marco Aurélio Ramirez, Farias, Alessandro S., Moraes-Vieira, Pedro Manoel M., Bizzacchi, Joyce Maria Annichino, Teesalu, Tambet, Chaim, Felipe David Mendonça, Cazzo, Everton, Chaim, Elinton Adami, Proença-Módena, José Luiz, Martins-de-Souza, Daniel, Osako, Mariana Kiomy, Leiria, Luiz Osório, Mori, Marcelo A.
Published in Nature communications

Phenotypic changes in low-density lipoprotein particles as markers of adverse clinical outcomes in COVID-19

by Carmo, Helison Rafael P., Yoshinaga, Marcos Y., Castillo, Alejandro Rosell, Britto Chaves-Filho, Adriano, Bonilha, Isabella, Barreto, Joaquim, Muraro, Stéfanie Primon, de Souza, Gabriela Fabiano, Davanzo, Gustavo Gastão, Perroud, Maurício W., Lukhna, Kishal, Ntsekhe, Mpiko, Davidson, Sean, Velloso, Licio A., Nadruz, Wilson, Carvalho, Luiz Sérgio F., Sáinz-Jaspeado, Miguel, Farias, Alessandro S., Proença-Módena, José Luiz, Moraes-Vieira, Pedro M., Karathanasis, Sotirios K., Yellon, Derek, Miyamoto, Sayuri, Remaley, Alan T., Sposito, Andrei C.
Published in Molecular genetics and metabolism

Zika Virus Strains and Dengue Virus Induce Distinct Proteomic Changes in Neural Stem Cells and Neurospheres

by Nascimento, Juliana Minardi, Gouvêa-Junqueira, Danielle, Zuccoli, Giuliana S., Pedrosa, Carolina da Silva Gouveia, Brandão-Teles, Caroline, Crunfli, Fernanda, Antunes, André S. L. M., Cassoli, Juliana S., Karmirian, Karina, Salerno, José Alexandre, de Souza, Gabriela Fabiano, Muraro, Stéfanie Primon, Proenca-Módena, Jose Luiz, Higa, Luiza M., Tanuri, Amilcar, Garcez, Patricia P., Rehen, Stevens K., Martins-de-Souza, Daniel
Published in Molecular neurobiology

Detection of SARS-CoV-2 virus via dynamic light scattering using antibody-gold nanoparticle bioconjugates against viral spike protein

by Silva, Patricia Bento da, Silva, Jaqueline Rodrigues da, Rodrigues, Mosar Corrêa, Vieira, Julia Augusto, Andrade, Ikaro Alves de, Nagata, Tatsuya, Santos, Alexandre Silva, Silva, Sebastião William da, Rocha, Marcia Cristina Oliveira da, Báo, Sônia Nair, Moraes-Vieira, Pedro M., Proença-Modena, José, Angelim, Monara K.C., de Souza, Gabriela Fabiano, Muraro, Stefanie Primon, de Barros, André Luis Branco, de Souza Martins, Glêndara Aparecida, Ribeiro-Dias, Fátima, Machado, Giovanna, Fessel, Melissa Regina, Chudzinski-Tavassi, Ana Marisa, Ronconi, Célia Machado, Gonçalves, Debora, Curi, Rui, Oliveira, Osvaldo N., Azevedo, Ricardo Bentes
Published in Talanta (Oxford)

Impact of Microbiota Depletion by Antibiotics on SARS-CoV-2 Infection of K18-hACE2 Mice

by Rodrigues, Patrícia Brito, Gomes, Giovanni Freitas, Angelim, Monara K. S. C, Souza, Gabriela F, Muraro, Stefanie Primon, Toledo-Teixeira, Daniel A, Rattis, Bruna Amanda Cruz, Passos, Amanda Stephane, Pral, Laís Passarielo, de Rezende Rodovalho, Vinícius, dos Santos P. Gomes, Arilson Bernardo, Matheus, Valquíria Aparecida, Antunes, André Saraiva Leão Marcelo, Crunfli, Fernanda, Antunes, Krist Helen, de Souza, Ana Paula Duarte, Consonni, Sílvio Roberto, Leiria, Luiz Osório, Alves-Filho, José Carlos, Cunha, Thiago M, Moraes-Vieira, Pedro M. M, Proença-Módena, José Luiz, R. Vinolo, Marco Aurélio
Published in Cells (Basel, Switzerland)

TAM and TIM receptors mRNA expression in Zika virus infected placentas

by Nobrega, Guilherme M., Samogim, Ana Paula, Parise, Pierina L., Venceslau, Emanuella M., Guida, José Paulo S., Japecanga, Rodolfo R., Amorim, Mariene R., Toledo-Teixeira, Daniel A., Forato, Julia, Consonni, Sílvio R., Costa, Maria Laura, Proenca-Modena, José Luiz, Amaral, Eliana, Besteti Pires Mayer-Milanez, Helaine Maria, Ribeiro-do-Valle, Carolina C., Calil, Roseli, Bennini Junior, João Renato, Lajos, Giuliane Jesus, Altemani, Albina, Moretti, Maria Luiza, Resende, Mariangela Ribeiro, Garcia, Márcia Teixeira, Angerami, Rodrigo Nogueira, Nolasco da Silva, Marcos Tadeu, Coan, Ana Carolina, Colella-Santos, Maria Francisca, Bruno von Zuben, Andrea Paula, Ribas Freitas, André Ricardo, Ramirez Vinolo, Marco Aurélio, Catharino, Rodrigo Ramos, Maranhão Costa, Fábio Trindade, Arns, Clarice Weis, Vieira, Aline, Fabiano de Souza, Gabriela, Bispo dos Santos, Karina, Amorim, Mariene Ribeiro, Martini, Matheus Cavalheiro, Muraro, Stéfanie Primon
Published in Placenta (Eastbourne)

SARS-CoV-2 uses CD4 to infect T helper lymphocytes

by Brunetti, Natalia S, Davanzo, Gustavo G, de Moraes, Diogo, Ferrari, Allan J R, Souza, Gabriela F, Muraro, Stéfanie Primon, Knittel, Thiago L, Boldrini, Vinicius O, Monteiro, Lauar B, Virgílio-da-Silva, João Victor, Profeta, Gerson S, Wassano, Natália S, Nunes Santos, Luana, Carregari, Victor C, Dias, Artur H S, Veras, Flavio P, Tavares, Lucas A, Forato, Julia, Castro, Icaro M S, Silva-Costa, Lícia C, Palma, André C, Mansour, Eli, Ulaf, Raisa G, Bernardes, Ana F, Nunes, Thyago A, Ribeiro, Luciana C, Agrela, Marcus V, Moretti, Maria Luiza, Buscaratti, Lucas I, Crunfli, Fernanda, Ludwig, Raissa G, Gerhardt, Jaqueline A, Munhoz-Alves, Natália, Marques, Ana Maria, Sesti-Costa, Renata, Amorim, Mariene R, Toledo-Teixeira, Daniel A, Parise, Pierina Lorencini, Martini, Matheus Cavalheiro, Bispos-Dos-Santos, Karina, Simeoni, Camila L, Granja, Fabiana, Silvestrini, Virgínia C, de Oliveira, Eduardo B, Faca, Vitor M, Carvalho, Murilo, Castelucci, Bianca G, Pereira, Alexandre B, Coimbra, Laís D, Dias, Marieli M G, Rodrigues, Patricia B, Gomes, Arilson Bernardo S P, Pereira, Fabricio B, Santos, Leonilda M B, Bloyet, Louis-Marie, Stumpf, Spencer, Pontelli, Marjorie C, Whelan, Sean, Sposito, Andrei C, Carvalho, Robson F, Vieira, André S, Vinolo, Marco A R, Damasio, André, Velloso, Licio, Figueira, Ana Carolina M, da Silva, Luis L P, Cunha, Thiago Mattar, Nakaya, Helder I, Marques-Souza, Henrique, Marques, Rafael E, Martins-de-Souza, Daniel, Skaf, Munir S, Proenca-Modena, Jose Luiz, Moraes-Vieira, Pedro M M, Mori, Marcelo A, Farias, Alessandro S
Published in eLife

Zika Virus Infection of Murine and Human Neutrophils and their Function as Trojan Horses to the Placenta

by Zanluqui, Nagela Gabdhan, Lilian Gomes Oliveira, Polonio, Carolina M, Tabata, Takahashi Franca, Fabiano, Gabriela S, Stefanie Primon Muraro, Amorim, Mariene R, Carregari, Victor Corasolla, Brandao-Teles, Carolina, Patrick Da Silva, Marilia Garcia Oliveira, Rafael Freitas Oliveira-Franca, Marielton Passos Cunha, Nogueira, Mauricio, Daniel Martins Souza, Condino-Neto, Antonio, Proenca-Modena, Jose Luiz, Jean Pierre Schatzmann Peron
Published in bioRxiv

Increased mTOR signaling, impaired autophagic flux and cell-to-cell viral transmission are hallmarks of SARS-CoV-2 infection

by Grazielle Celeste Maktura, Thomaz Luscher Dias, Erika Pereira Zambalde, Brenha, Bianca, Amorim, Mariene R, Luana Nunes Santos, Lucas Buscaratti, Joao Gabriel De Angeli Elston, Mara, Cynthia, Mariana Camargo Silva Mancini, Isadora Carolina Betim Pavan, Toledo-Teixeira, Daniel A, Bispo-Dos-Santos, Karina, Parise, Pierina L, Stefanie Primon Muraro, Gabriela Fabiano De Souza, Ana Paula Morelli, Luiz Guilherme Salvino Da Silva, Icaro Maia Santos De Castro, Guilherme Oliveira Barbosa, Ludwig, Raissa G, Knittel, Thiago L, Saccon, Tatiana D, Mori, Marcelo A, Granja, Fabiana, Carvalho, Hernandes F, Luis Lamberti Pinto Da Silva, Nakaya, Helder I, Proenca-Modena, Jose Luiz, Fernando Moreira Simabuco, Marques-Souza, Henrique
Published in bioRxiv