Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface

by Weight, Caroline M, Venturini, Cristina, Pojar, Sherin, Jochems, Simon P, Reiné, Jesús, Nikolaou, Elissavet, Solórzano, Carla, Noursadeghi, Mahdad, Brown, Jeremy S, Ferreira, Daniela M, Heyderman, Robert S
Published in Nature communications

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

by Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Hill, Helen, Lazarus, Rajeka, Lawrie, Alison M, McGregor, Alastair, Villafana, Tonya L, Gilbert, Sarah C, Aban, Marites, Aboagye, Jeremy, Adam, Matthew, Adams, Kirsty, Alves, Mariana P.S., Barnes, Eleanor, Berrie, Eleanor, Bewley, Kevin R., Bletchly, Heather, Borthwick, Nicola, Brown, Phillip, Buttigieg, Karen R., Cashen, Paul, Castro, Lucia Carratala, Chadwick, Jim, Chapman, David, Charlton, Sue, Clark, Matthew, Clutterbuck, Elizabeth A., Cooper, Cushla, Cooper, Rachel, Darroch, Paula, Dearlove, David, Drake-Brockman, Rachael, van Eck, Samual, Farrar, Madi, Fraiman, Pedro H.A., Gracie, Lara, Grossi, Leonardo, Hanrath, Aidan T., Harris, Tara, Hassan, Shadin, Hay, Jodie, Head, Ian, Hodges, Gina, Horne, Elizea, Hou, Mimi M., Humphries, Holly E., Hyder-Wright, Angela, Jeffers, Helen, Karampatsas, Konstantinos, Keen, Jade, Khan, Liaquat, King, Thomas B., Klenerman, Paul, Lees, Emily A., Li, Yuanyuan, Loew, Lisa, Marques, Gabriela N., Masilela, Mduduzi, Mathew, Moncy, Meijs, Wilma, Morris, Susan, Mpelembue, Mushiya, Noal, Helena, Nugent, Fay L., O'Connor, Daniel, Olchawski, Victoria, O'Reilly, Paula, Phillips, Daniel J., Pickup, Lorinda, Du Plessis, Joan, Pollard, Samuel, Poulton, Ian, Pulido, David, Reiné, Jesús, Resuello-Dauti, Mila, Richter, Alex, Roche, Sophie, Rollier, Christine, Ruiz, Sarah, Sala, Claudia, Sanchez-Gonzalez, Amada, Sharpe, Hannah E., Smith, Daniel C., Smith, Holly E., Soares, Tiago, Souza, Cinthia M.C.D.L., Spina, Fernanda, Steven, Jill, Stockdale, Lisa, Stockwell, Lisa V., Sturdy, Ann, Tarr, Alexander W., Taylor, Ursula, Themistocleous, Andreas, Tsheko, Betty Lebogang, Turabi, Aadil, Waddington, Claire S., Wallis, Erica, Webb, Stewart
Published in The Lancet (British edition)

Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-i...

by Liu, Xinxue, Shaw, Robert H, Stuart, Arabella S V, Greenland, Melanie, Aley, Parvinder K, Andrews, Nick J, Cameron, J Claire, Charlton, Sue, Clutterbuck, Elizabeth A, Collins, Andrea M, Dinesh, Tanya, England, Anna, Faust, Saul N, Ferreira, Daniela M, Finn, Adam, Green, Christopher A, Hallis, Bassam, Heath, Paul T, Hill, Helen, Lambe, Teresa, Lazarus, Rajeka, Libri, Vincenzo, Long, Fei, Mujadidi, Yama F, Plested, Emma L, Provstgaard-Morys, Samuel, Ramasamy, Maheshi N, Ramsay, Mary, Read, Robert C, Robinson, Hannah, Singh, Nisha, Turner, David P J, Turner, Paul J, Walker, Laura L, White, Rachel, Nguyen-Van-Tam, Jonathan S, Snape, Matthew D, Munro, Alasdair P S, Bartholomew, Jazz, Presland, Laura, Horswill, Sarah, Warren, Sarah, Varkonyi-Clifford, Sophie, Saich, Stephen, Adams, Kirsty, Ricamara, Marivic, Turner, Nicola, Yee Ting, Nicole Y, Whittley, Sarah, Rampling, Tommy, Desai, Amisha, Brown, Claire H, Qureshi, Ehsaan, Gokani, Karishma, Naker, Kush, Kellett Wright, Johanna K, Williams, Rachel L, Riaz, Tawassal, Penciu, Florentina D, Di Maso, Claudio, Howe, Elizabeth G, Vichos, Iason, Ghulam Farooq, Mujtaba, Noristani, Rabiullah, Yao, Xin L, Oldfield, Neil J, Hammersley, Daniel, Belton, Sue, Royal, Simon, San Francisco Ramos, Alberto, Hultin, Cecilia, Galiza, Eva P, Shiham, Farah, Solórzano, Carla, Sainsbury, Hannah, Davies, Kelly, Ambrose, Pauline, Hitchins, Lisa, Baker, Natalie, Leung, Stephanie, Fothergill, Ross, Godwin, Kerry, Buttigieg, Karen, Shaik, Imam, Brown, Phill, Knight, Chanice, Lall, Paminder, Allen, Lauren
Published in The Lancet (British edition)

The nose is the best niche for detection of experimental pneumococcal colonisation in adults of all ages, using nasal wash

by Nikolaou, Elissavet, German, Esther L, Blizard, Annie, Howard, Ashleigh, Hitchins, Lisa, Chen, Tao, Chadwick, Jim, Pojar, Sherin, Mitsi, Elena, Solórzano, Carla, Sunny, Syba, Dunne, Felicity, Gritzfeld, Jenna F, Adler, Hugh, Hinds, Jason, Gould, Katherine A, Rylance, Jamie, Collins, Andrea M, Gordon, Stephen B, Ferreira, Daniela M
Published in Scientific reports

Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization

by Jochems, Simon P, de Ruiter, Karin, Solórzano, Carla, Voskamp, Astrid, Mitsi, Elena, Nikolaou, Elissavet, Carniel, Beatriz F, Pojar, Sherin, German, Esther L, Reiné, Jesús, Soares-Schanoski, Alessandra, Hill, Helen, Robinson, Rachel, Hyder-Wright, Angela D, Weight, Caroline M, Durrenberger, Pascal F, Heyderman, Robert S, Gordon, Stephen B, Smits, Hermelijn H, Urban, Britta C, Rylance, Jamie, Collins, Andrea M, Wilkie, Mark D, Lazarova, Lepa, Leong, Samuel C, Yazdanbakhsh, Maria, Ferreira, Daniela M
Published in The Journal of clinical investigation

Two Randomized Trials of the Effect of Live Attenuated Influenza Vaccine on Pneumococcal Colonization

by Rylance, Jamie, de Steenhuijsen Piters, Wouter A A, Mina, Michael J, Bogaert, Debby, French, Neil, Ferreira, Daniela M
Published in American journal of respiratory and critical care medicine

Old World cutaneous leishmaniasis treatment response varies depending on parasite species, geographical location and development of secondary infection

by Al-Salem, Waleed S, Solórzano, Carla, Weedall, Gareth D, Dyer, Naomi A, Kelly-Hope, Louise, Casas-Sánchez, Aitor, Alraey, Yasser, Alyamani, Essam J, Halliday, Alice, Balghonaim, Salah M, Alsohibany, Khalid S, Alzeyadi, Zeyad, Alzahrani, Mohamed H, Al-Shahrani, Ali M, Assiri, Abdullah M, Memish, Ziad, Acosta-Serrano, Álvaro
Published in Parasites & vectors

Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine

by Carniel, Beatriz F, Marcon, Fernando, Rylance, Jamie, German, Esther L, Zaidi, Seher, Reiné, Jesus, Negera, Edessa, Nikolaou, Elissavet, Pojar, Sherin, Solórzano, Carla, Collins, Andrea M, Connor, Victoria, Bogaert, Debbie, Gordon, Stephen B, Nakaya, Helder I, Ferreira, Daniela M, Jochems, Simon P, Mitsi, Elena
Published in JCI insight

Association between household air pollution and nasopharyngeal pneumococcal carriage in Malawian infants (MSCAPE): a nested, prospective, observational study

by Dherani, Mukesh K, Pope, Daniel, Tafatatha, Terence, Heinsbroek, Ellen, Chartier, Ryan, Mwalukomo, Thandie, Crampin, Amelia, Mitsi, Elena, German, Esther L, Nikolaou, Elissavet, Solórzano, Carla, Ferreira, Daniela M, Swarthout, Todd D, Hinds, Jason, Mortimer, Kevin, Gordon, Stephen B, French, Neil, Bruce, Nigel G
Published in The Lancet global health

Experimental Human Pneumococcal Colonization in Older Adults Is Feasible and Safe, Not Immunogenic

by Adler, Hugh, German, Esther L, Mitsi, Elena, Nikolaou, Elissavet, Pojar, Sherin, Hales, Caz, Robinson, Rachel, Connor, Victoria, Hill, Helen, Hyder-Wright, Angela D, Lazarova, Lepa, Lowe, Catherine, Smith, Emma L, Wheeler, India, Zaidi, Seher R, Jochems, Simon P, Loukov, Dessi, Reiné, Jesús, Solórzano-Gonzalez, Carla, de Gorguette d'Argoeuves, Polly, Jones, Tessa, Goldblatt, David, Chen, Tao, Aston, Stephen J, French, Neil, Collins, Andrea M, Gordon, Stephen B, Ferreira, Daniela M, Rylance, Jamie
Published in American journal of respiratory and critical care medicine