Pivotal Role of Innate and Adaptive Immunity in Anthracycline Chemotherapy of Established Tumors

by MATTAROLLO, Stephen R, LOI, Sherene, DURET, Helene, MA, Yuting, ZITVOGEL, Laurence, SMYTH, Mark J
Published in Cancer research (Chicago, Ill.)

Antimetastatic Effects of Blocking PD-1 and the Adenosine A2A Receptor

by MITTAL, Deepak, YOUNG, Arabella, STANNARD, Kimberley, YONG, Michelle, TENG, Michele W. L, ALLARD, Bertrand, STAGG, John, SMYTH, Mark J
Published in Cancer research (Chicago, Ill.)

Adenosine 2B Receptor Expression on Cancer Cells Promotes Metastasis

by Mittal, Deepak, Sinha, Debottam, Barkauskas, Deborah, Young, Arabella, Kalimutho, Murugan, Stannard, Kimberley, Caramia, Franco, Haibe-Kains, Benjamin, Stagg, John, Khanna, Kum Kum, Loi, Sherene, Smyth, Mark J
Published in Cancer research (Chicago, Ill.)

TRAIL+ NK Cells Control CD4+ T Cell Responses during Chronic Viral Infection to Limit Autoimmunity

by Schuster, Iona S., Wikstrom, Matthew E., Brizard, Geraldine, Coudert, Jerome D., Estcourt, Marie J., Manzur, Mitali, O’Reilly, Lorraine A., Smyth, Mark J., Trapani, Joseph A., Hill, Geoffrey R., Andoniou, Christopher E., Degli-Esposti, Mariapia A.
Published in Immunity (Cambridge, Mass.)

IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting

by Takeda, Kazuyoshi, Nakayama, Masafumi, Hayakawa, Yoshihiro, Kojima, Yuko, Ikeda, Hiroaki, Imai, Naoko, Ogasawara, Kouetsu, Okumura, Ko, Thomas, David M, Smyth, Mark J
Published in Nature communications

Improving cancer immunotherapy by targeting tumor-induced immune suppression

by Stewart, Trina J., Smyth, Mark J.
Published in Cancer and metastasis reviews

Adaptive immunity maintains occult cancer in an equilibrium state

by Smyth, Mark J, Schreiber, Robert D, Koebel, Catherine M, Vermi, William, Swann, Jeremy B, Zerafa, Nadeen, Rodig, Scott J, Old, Lloyd J
Published in Nature

Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy

by Stagg, John, Loi, Sherene, Divisekera, Upulie, Ngiow, Shin Foong, Duret, Helene, Yagita, Hideo, Teng, Michele W, Smyth, Mark J
Published in Proceedings of the National Academy of Sciences - PNAS

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

by Linterman, Michelle A, Beaton, Laura, Yu, Di, Ramiscal, Roybel R, Srivastava, Monika, Hogan, Jennifer J, Verma, Naresh K, Smyth, Mark J, Rigby, Robert J, Vinuesa, Carola G
Published in The Journal of experimental medicine

Tumor Cell Death and ATP Release Prime Dendritic Cells and Efficient Anticancer Immunity

by AYMERIC, Laetitia, APETOH, Lionel, GHIRINGHELLI, François, TESNIERE, Antoine, MARTINS, Isabelle, KROEMER, Guido, SMYTH, Mark J, ZITVOGEL, Laurence
Published in Cancer research (Chicago, Ill.)

G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis

by Casciello, Francesco, Al-Ejeh, Fares, Kelly, Greg, Brennan, Donal J., Ngiow, Shin Foong, Young, Arabella, Stoll, Thomas, Windloch, Karolina, Hill, Michelle M., Smyth, Mark J., Gannon, Frank, Lee, Jason S.
Published in Proceedings of the National Academy of Sciences - PNAS

CD73-Deficient Mice Have Increased Antitumor Immunity and Are Resistant to Experimental Metastasis

by STAGG, John, DIVISEKERA, Upulie, DURET, Helene, SPARWASSER, Tim, TENG, Michele W. L, DARCY, Phillip K, SMYTH, Mark J
Published in Cancer research (Chicago, Ill.)

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

by Stagg, John, Divisekera, Upulie, McLaughlin, Nicole, Sharkey, Janelle, Pommey, Sandra, Denoyer, Delphine, Dwyer, Karen M, Smyth, Mark J
Published in Proceedings of the National Academy of Sciences - PNAS

Interleukin-21-Producing CD4+ T Cells Promote Type 2 Immunity to House Dust Mites

by Coquet, Jonathan M., Schuijs, Martijn J., Smyth, Mark J., Deswarte, Kim, Beyaert, Rudi, Braun, Harald, Boon, Louis, Hedestam, Gunilla B. Karlsson, Nutt, Steven L., Hammad, Hamida, Lambrecht, Bart N.
Published in Immunity (Cambridge, Mass.)

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

by Zotos, Dimitra, Coquet, Jonathan M, Zhang, Yang, Light, Amanda, D'Costa, Kathy, Kallies, Axel, Corcoran, Lynn M, Godfrey, Dale I, Toellner, Kai-Michael, Smyth, Mark J, Nutt, Stephen L, Tarlinton, David M
Published in The Journal of experimental medicine

Radiotherapy Complements Immune Checkpoint Blockade

by Ngiow, Shin Foong, McArthur, Grant A., Smyth, Mark J.
Published in Cancer cell

Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche

by SCENEAY, Jaclyn, CHOW, Melvyn T, MÖLLER, Andreas, CHEW, Anna, HALSE, Heloise M, WONG, Christina S. F, ANDREWS, Daniel M, SLOAN, Erica K, PARKER, Belinda S, BOWTELL, David D, SMYTH, Mark J
Published in Cancer research (Chicago, Ill.)

Cancer immunoediting by the innate immune system in the absence of adaptive immunity

by O'Sullivan, Timothy, Saddawi-Konefka, Robert, Vermi, William, Koebel, Catherine M, Arthur, Cora, White, J Michael, Uppaluri, Ravi, Andrews, Daniel M, Ngiow, Shin Foong, Teng, Michele W L, Smyth, Mark J, Schreiber, Robert D, Bui, Jack D
Published in The Journal of experimental medicine

Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies

by VERBRUGGE, Inge, HAGEKYRIAKOU, Jim, HAYNES, Nicole M, SHARP, Leslie L, GALLI, Mara, WEST, Alison, MCLAUGHLIN, Nicole M, DURET, Hélène, YAGITA, Hideo, JOHNSTONE, Ricky W, SMYTH, Mark J
Published in Cancer research (Chicago, Ill.)

Myeloid immunosuppression and immune checkpoints in the tumor microenvironment

by Nakamura, Kyohei, Smyth, Mark J
Published in Cellular & molecular immunology