Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection

by Song, Ge, He, Wan-Ting, Callaghan, Sean, Anzanello, Fabio, Huang, Deli, Ricketts, James, Torres, Jonathan L, Beutler, Nathan, Peng, Linghang, Vargas, Sirena, Cassell, Jon, Parren, Mara, Yang, Linlin, Ignacio, Caroline, Smith, Davey M, Voss, James E, Nemazee, David, Ward, Andrew B, Rogers, Thomas, Burton, Dennis R, Andrabi, Raiees
Published in Nature communications

Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study

by Reiman, Eric M, Arboleda-Velasquez, Joseph F, Quiroz, Yakeel T, Huentelman, Matthew J, Beach, Thomas G, Caselli, Richard J, Chen, Yinghua, Su, Yi, Myers, Amanda J, Hardy, John, Paul Vonsattel, Jean, Younkin, Steven G, Bennett, David A, De Jager, Philip L, Larson, Eric B, Crane, Paul K, Keene, C Dirk, Kamboh, M Ilyas, Kofler, Julia K, Duque, Linda, Gilbert, John R, Gwirtsman, Harry E, Buxbaum, Joseph D, Dickson, Dennis W, Frosch, Matthew P, Ghetti, Bernardino F, Lunetta, Kathryn L, Wang, Li-San, Hyman, Bradley T, Kukull, Walter A, Foroud, Tatiana, Haines, Jonathan L, Mayeux, Richard P, Pericak-Vance, Margaret A, Schneider, Julie A, Trojanowski, John Q, Farrer, Lindsay A, Schellenberg, Gerard D, Beecham, Gary W, Montine, Thomas J, Jun, Gyungah R
Published in Nature communications

Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans

by Wei, Wei, Pagnamenta, Alistair T, Gleadall, Nicholas, Sanchis-Juan, Alba, Stephens, Jonathan, Broxholme, John, Tuna, Salih, Odhams, Christopher A, Fratter, Carl, Turro, Ernest, Caulfield, Mark J, Taylor, Jenny C, Rahman, Shamima, Chinnery, Patrick F
Published in Nature communications

FcγRIIb differentially regulates pre-immune and germinal center B cell tolerance in mouse and human

by Espéli, Marion, Bashford-Rogers, Rachael, Sowerby, John M, Alouche, Nagham, Wong, Limy, Denton, Alice E, Linterman, Michelle A, Smith, Kenneth G C
Published in Nature communications

Non-coding variability at the APOE locus contributes to the Alzheimer's risk

by Zhou, Xiaopu, Chen, Yu, Mok, Kin Y, Kwok, Timothy C Y, Mok, Vincent C T, Guo, Qihao, Ip, Fanny C, Chen, Yuewen, Mullapudi, Nandita, Giusti-Rodríguez, Paola, Sullivan, Patrick F, Hardy, John, Fu, Amy K Y, Li, Yun, Ip, Nancy Y
Published in Nature communications

The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision

by Chrystal, Paul W, Lambacher, Nils J, Doucette, Lance P, Bellingham, James, Schiff, Elena R, Noel, Nicole C L, Li, Chunmei, Tsiropoulou, Sofia, Casey, Geoffrey A, Zhai, Yi, Nadolski, Nathan J, Majumder, Mohammed H, Tagoe, Julia, D'Esposito, Fabiana, Cordeiro, Maria Francesca, Downes, Susan, Clayton-Smith, Jill, Ellingford, Jamie, Mahroo, Omar A, Hocking, Jennifer C, Cheetham, Michael E, Webster, Andrew R, Jansen, Gert, Blacque, Oliver E, Allison, W Ted, Au, Ping Yee Billie, MacDonald, Ian M, Arno, Gavin, Leroux, Michel R
Published in Nature communications

AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders

by Salpietro, Vincenzo, Dixon, Christine L, Guo, Hui, Bello, Oscar D, Vandrovcova, Jana, Efthymiou, Stephanie, Maroofian, Reza, Heimer, Gali, Burglen, Lydie, Valence, Stephanie, Torti, Erin, Hacke, Moritz, Rankin, Julia, Tariq, Huma, Colin, Estelle, Procaccio, Vincent, Striano, Pasquale, Mankad, Kshitij, Lieb, Andreas, Chen, Sharon, Pisani, Laura, Bettencourt, Conceicao, Männikkö, Roope, Manole, Andreea, Brusco, Alfredo, Grosso, Enrico, Ferrero, Giovanni Battista, Armstrong-Moron, Judith, Gueden, Sophie, Bar-Yosef, Omer, Tzadok, Michal, Monaghan, Kristin G, Santiago-Sim, Teresa, Person, Richard E, Cho, Megan T, Willaert, Rebecca, Yoo, Yongjin, Chae, Jong-Hee, Quan, Yingting, Wu, Huidan, Wang, Tianyun, Bernier, Raphael A, Xia, Kun, Blesson, Alyssa, Jain, Mahim, Motazacker, Mohammad M, Jaeger, Bregje, Schneider, Amy L, Boysen, Katja, Muir, Alison M, Myers, Candace T, Gavrilova, Ralitza H, Gunderson, Lauren, Schultz-Rogers, Laura, Klee, Eric W, Dyment, David, Osmond, Matthew, Parellada, Mara, Llorente, Cloe, Gonzalez-Peñas, Javier, Carracedo, Angel, Van Haeringen, Arie, Ruivenkamp, Claudia, Nava, Caroline, Heron, Delphine, Nardello, Rosaria, Iacomino, Michele, Minetti, Carlo, Skabar, Aldo, Fabretto, Antonella, Raspall-Chaure, Miquel, Chez, Michael, Tsai, Anne, Fassi, Emily, Shinawi, Marwan, Constantino, John N, De Zorzi, Rita, Fortuna, Sara, Kok, Fernando, Keren, Boris, Bonneau, Dominique, Choi, Murim, Benzeev, Bruria, Zara, Federico, Mefford, Heather C, Scheffer, Ingrid E, Clayton-Smith, Jill, Macaya, Alfons, Rothman, James E, Eichler, Evan E, Kullmann, Dimitri M, Houlden, Henry
Published in Nature communications

Human and mouse essentiality screens as a resource for disease gene discovery

by Cacheiro, Pilar, Muñoz-Fuentes, Violeta, Murray, Stephen A, Dickinson, Mary E, Bucan, Maja, Nutter, Lauryl M J, Peterson, Kevin A, Haselimashhadi, Hamed, Flenniken, Ann M, Morgan, Hugh, Westerberg, Henrik, Konopka, Tomasz, Hsu, Chih-Wei, Christiansen, Audrey, Lanza, Denise G, Beaudet, Arthur L, Heaney, Jason D, Fuchs, Helmut, Gailus-Durner, Valerie, Sorg, Tania, Prochazka, Jan, Novosadova, Vendula, Lelliott, Christopher J, Wardle-Jones, Hannah, Wells, Sara, Teboul, Lydia, Cater, Heather, Stewart, Michelle, Hough, Tertius, Wurst, Wolfgang, Sedlacek, Radislav, Adams, David J, Seavitt, John R, Tocchini-Valentini, Glauco, Mammano, Fabio, Braun, Robert E, McKerlie, Colin, Herault, Yann, de Angelis, Martin Hrabě, Mallon, Ann-Marie, Lloyd, K C Kent, Brown, Steve D M, Parkinson, Helen, Meehan, Terrence F, Smedley, Damian
Published in Nature communications

Specialist multidisciplinary input maximises rare disease diagnoses from whole genome sequencing

by Macken, William L, Falabella, Micol, McKittrick, Caroline, Pizzamiglio, Chiara, Ellmers, Rebecca, Eggleton, Kelly, Woodward, Cathy E, Patel, Yogen, Labrum, Robyn, Phadke, Rahul, Reilly, Mary M, DeVile, Catherine, Sarkozy, Anna, Footitt, Emma, Davison, James, Rahman, Shamima, Houlden, Henry, Bugiardini, Enrico, Quinlivan, Rosaline, Hanna, Michael G, Vandrovcova, Jana, Pitceathly, Robert D S
Published in Nature communications

Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders

by Gracia-Diaz, Carolina, Zhou, Yijing, Yang, Qian, Maroofian, Reza, Espana-Bonilla, Paula, Lee, Chul-Hwan, Zhang, Shuo, Padilla, Natàlia, Fueyo, Raquel, Waxman, Elisa A, Lei, Sunyimeng, Otrimski, Garrett, Li, Dong, Sheppard, Sarah E, Mark, Paul, Harr, Margaret H, Hakonarson, Hakon, Rodan, Lance, Jackson, Adam, Vasudevan, Pradeep, Powel, Corrina, Mohammed, Shehla, Maddirevula, Sateesh, Alzaidan, Hamad, Faqeih, Eissa A, Efthymiou, Stephanie, Turchetti, Valentina, Rahman, Fatima, Maqbool, Shazia, Salpietro, Vincenzo, Ibrahim, Shahnaz H, di Rosa, Gabriella, Houlden, Henry, Alharbi, Maha Nasser, Al-Sannaa, Nouriya Abbas, Bauer, Peter, Zifarelli, Giovanni, Estaras, Conchi, Hurst, Anna C E, Thompson, Michelle L, Chassevent, Anna, Smith-Hicks, Constance L, de la Cruz, Xavier, Holtz, Alexander M, Elloumi, Houda Zghal, Hajianpour, M J, Rieubland, Claudine, Braun, Dominique, Banka, Siddharth, French, Deborah L, Heller, Elizabeth A, Saade, Murielle, Song, Hongjun, Ming, Guo-Li, Alkuraya, Fowzan S, Agrawal, Pankaj B, Reinberg, Danny, Bhoj, Elizabeth J, Martínez-Balbás, Marian A, Akizu, Naiara
Published in Nature communications

Author Correction: Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans

by Wei, Wei, Pagnamenta, Alistair T, Gleadall, Nicholas, Sanchis-Juan, Alba, Stephens, Jonathan, Broxholme, John, Tuna, Salih, Odhams, Christopher A, Fratter, Carl, Turro, Ernest, Caulfield, Mark J, Taylor, Jenny C, Rahman, Shamima, Chinnery, Patrick F
Published in Nature communications

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

by Permuth-Wey, Jennifer, Shen, Howard C, Tyrer, Jonathan P, Chen, Zhihua, Lin, Hui-Yi, Chen, Y Ann, Ramus, Susan J, Karevan, Rod, Larson, Melissa C, Anton-Culver, Hoda, Armasu, Sebastian M, Bacot, François, Bandera, Elisa V, Barnholtz-Sloan, Jill, Bloom, Greg, Brooks-Wilson, Angela, Brown, Robert, Butzow, Ralf, Cai, Qiuyin, Campbell, Ian, Chenevix-Trench, Georgia, Coetzee, Gerhard A, Cook, Linda S, Couch, Fergus J, Cramer, Daniel W, Cunningham, Julie M, Despierre, Evelyn, Doherty, Jennifer A, du Bois, Andreas, Dürst, Matthias, Easton, Douglas F, Edwards, Robert, Ekici, Arif B, Fenstermacher, David A, Flanagan, James M, Garcia-Closas, Montserrat, Goodman, Marc T, Gore, Martin, Gronwald, Jacek, Halle, Mari K, Harter, Philipp, Hillemanns, Peter, Høgdall, Claus K, Hosono, Satoyo, Jakubowska, Anna, Jensen, Allan, Jim, Heather, Kalli, Kimberly R, Kaye, Stanley B, Kelemen, Linda E, Kikkawa, Fumitaka, Konecny, Gottfried E, Krakstad, Camilla, Kjaer, Susanne Krüger, Kupryjanczyk, Jolanta, Lancaster, Johnathan M, Le, Nhu D, Liang, Dong, Lim, Boon Kiong, Lin, Jie, Lissowska, Jolanta, Lu, Karen H, Matsuo, Keitaro, Moysich, Kirsten B, Ness, Roberta B, Nevanlinna, Heli, Odunsi, Kunle, Orlow, Irene, Pejovic, Tanja, Pike, Malcolm C, Poole, Elizabeth M, Renner, Stefan P, Rodriguez-Rodriguez, Lorna, Rossing, Mary Anne, Rzepecka, Iwona K, Salvesen, Helga B, Severi, Gianluca, Shu, Xiao-Ou, Shvetsov, Yurii B, Song, Honglin, Spiewankiewicz, Beata, Stram, Daniel, Sutphen, Rebecca, Teo, Soo-Hwang, Terry, Kathryn L, Thompson, Pamela J, van Altena, Anne M, Vergote, Ignace, Vierkant, Robert A, Wang-Gohrke, Shan, Palmieri Weber, Rachel, Wik, Elisabeth, Wilkens, Lynne R, Woo, Yin Ling, Ziogas, Argyrios, Phelan, Catherine M, Berchuck, Andrew, Fridley, Brooke L, Pharoah, Paul D P, Sellers, Thomas A
Published in Nature communications