Identification and description of three families with familial Alzheimer disease that segregate variants in the SORL1 gene by Thonberg, Håkan, Chiang, Huei-Hsin, Lilius, Lena, Forsell, Charlotte, Lindström, Anna-Karin, Johansson, Charlotte, Björkström, Jenny, Thordardottir, Steinunn, Sleegers, Kristel, Van Broeckhoven, Christine, Rönnbäck, Annica, Graff, Caroline

Get full text

The Secure Anonymised Information Linkage databank Dementia e-cohort (SAIL-DeC) by Schnier, C, Wilkinson, T, Akbari, A, Orton, C, Sleegers, K, Gallacher, J, Lyons, R A, Sudlow, Clm

Get full text

Altered deactivation in individuals with genetic risk for Alzheimer's disease by Persson, J., Lind, J., Larsson, A., Ingvar, M., Sleegers, K., Van Broeckhoven, C., Adolfsson, R., Nilsson, L.-G., Nyberg, L.

Get full text

The Association between APOE Genotype and Memory Dysfunction in Subjects with Mild Cognitive Impairment Is Related to Age and Alzheimer Pathology by Ramakers, I.H.G.B., Visser, P.J., Aalten, P., Bekers, O., Sleegers, K., van Broeckhoven, C.L., Jolles, J., Verhey, F.R.J.

Get full text

Octapeptide repeat insertions in the prion protein gene and early onset dementia by Croes, E A, Theuns, J, Houwing-Duistermaat, J J, Dermaut, B, Sleegers, K, Roks, G, Van den Broeck, M, van Harten, B, van Swieten, J C, Cruts, M, Van Broeckhoven, C, van Duijn, C M

Get full text

Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum by Bos, Isabelle, Vos, Stephanie, Verhey, Frans, Scheltens, Philip, Teunissen, Charlotte, Engelborghs, Sebastiaan, Sleegers, Kristel, Frisoni, Giovanni, Blin, Olivier, Richardson, Jill C., Bordet, Régis, Tsolaki, Magda, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Lleó, Alberto, Johannsen, Peter, Freund-Levi, Yvonne, Frölich, Lutz, Vandenberghe, Rik, Westwood, Sarah, Dobricic, Valerija, Barkhof, Frederik, Legido-Quigley, Cristina, Bertram, Lars, Lovestone, Simon, Streffer, Johannes, Andreasson, Ulf, Blennow, Kaj, Zetterberg, Henrik, Visser, Pieter Jelle

Get full text

Familial clustering and genetic risk for dementia in a genetically isolated Dutch population by Sleegers, K., Roks, G., Theuns, J., Aulchenko, Y. S., Rademakers, R., Cruts, M., van Gool, W. A., Van Broeckhoven, C., Heutink, P., Oostra, B. A., van Swieten, J. C., van Duijn, C. M.

Get full text

Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset by Hong, Shengjun, Prokopenko, Dmitry, Dobricic, Valerija, Kilpert, Fabian, Bos, Isabelle, Vos, Stephanie J B, Tijms, Betty M, Andreasson, Ulf, Blennow, Kaj, Vandenberghe, Rik, Cleynen, Isabelle, Gabel, Silvy, Schaeverbeke, Jolien, Scheltens, Philip, Teunissen, Charlotte E, Niemantsverdriet, Ellis, Engelborghs, Sebastiaan, Frisoni, Giovanni, Blin, Olivier, Richardson, Jill C, Bordet, Regis, Molinuevo, José Luis, Rami, Lorena, Kettunen, Petronella, Wallin, Anders, Lleó, Alberto, Sala, Isabel, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Dobson, Richard J B, Legido-Quigley, Cristina, Sleegers, Kristel, Van Broeckhoven, Christine, Ten Kate, Mara, Barkhof, Frederik, Zetterberg, Henrik, Lovestone, Simon, Streffer, Johannes, Wittig, Michael, Franke, Andre, Tanzi, Rudolph E, Visser, Pieter Jelle, Bertram, Lars

Get full text

The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics by Bos, Isabelle, Vos, Stephanie, Vandenberghe, Rik, Scheltens, Philip, Engelborghs, Sebastiaan, Frisoni, Giovanni, Molinuevo, José Luis, Wallin, Anders, Lleó, Alberto, Popp, Julius, Martinez-Lage, Pablo, Baird, Alison, Dobson, Richard, Legido-Quigley, Cristina, Sleegers, Kristel, Van Broeckhoven, Christine, Bertram, Lars, Ten Kate, Mara, Barkhof, Frederik, Zetterberg, Henrik, Lovestone, Simon, Streffer, Johannes, Visser, Pieter Jelle

Get full text

APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy by Sleegers, Kristel, Brouwers, Nathalie, Gijselinck, Ilse, Theuns, Jessie, Goossens, Dirk, Wauters, Jan, Del-Favero, Jurgen, Cruts, Marc, Duijn, Cornelia M. van, Broeckhoven, Christine Van

Get full text

Cyclin-dependent kinase 5 is associated with risk for Alzheimer’s disease in a Dutch population-based study by Arias-Vásquez, A., Aulchenko, Y. S., Isaacs, A., van Oosterhout, A., Sleegers, K., Hofman, A., van Broeckhoven, C., Oostra, B. A., Breteler, M., van Duijn, C. M.

Get full text

Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease by Visser, Pieter Jelle, Reus, Lianne M, Gobom, Johan, Jansen, Iris, Dicks, Ellen, van der Lee, Sven J, Tsolaki, Magda, Verhey, Frans R J, Popp, Julius, Martinez-Lage, Pablo, Vandenberghe, Rik, Lleó, Alberto, Molinuevo, José Luís, Engelborghs, Sebastiaan, Freund-Levi, Yvonne, Froelich, Lutz, Sleegers, Kristel, Dobricic, Valerija, Lovestone, Simon, Streffer, Johannes, Vos, Stephanie J B, Bos, Isabelle, Smit, August B, Blennow, Kaj, Scheltens, Philip, Teunissen, Charlotte E, Bertram, Lars, Zetterberg, Henrik, Tijms, Betty M

Get full text

A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer’s disease by Verheijen, Jan, Van den Bossche, Tobi, van der Zee, Julie, Engelborghs, Sebastiaan, Sanchez-Valle, Raquel, Lladó, Albert, Graff, Caroline, Thonberg, Håkan, Pastor, Pau, Ortega-Cubero, Sara, Pastor, Maria A., Benussi, Luisa, Ghidoni, Roberta, Binetti, Giuliano, Clarimon, Jordi, Lleó, Alberto, Fortea, Juan, de Mendonça, Alexandre, Martins, Madalena, Grau-Rivera, Oriol, Gelpi, Ellen, Bettens, Karolien, Mateiu, Ligia, Dillen, Lubina, Cras, Patrick, De Deyn, Peter P., Van Broeckhoven, Christine, Sleegers, Kristel

Get full text

A Pan-European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats by van der Zee, Julie, Dillen, Lubina, Van Langenhove, Tim, Engelborghs, Sebastiaan, Philtjens, Stéphanie, Vandenbulcke, Mathieu, Sleegers, Kristel, Sieben, Anne, Bäumer, Veerle, Borroni, Barbara, Padovani, Alessandro, Archetti, Silvana, Perneczky, Robert, Diehl-Schmid, Janine, de Mendonça, Alexandre, Miltenberger-Miltenyi, Gabriel, Pimentel, José, Graff, Caroline, Chiang, Huei-Hsin, Sanchez-Valle, Raquel, Llado, Albert, Gelpi, Ellen, Santiago, Beatriz, Frisoni, Giovanni, Zanetti, Orazio, Bonvicini, Cristian, vom Hagen, Jennifer Müller, Schöls, Ludger, Heneka, Michael T., Matej, Radoslav, Parobkova, Eva, Kovacs, Gabor G., Ströbel, Thomas, Sarafov, Stayko, Tournev, Ivailo, Jordanova, Albena, Danek, Adrian, Arzberger, Thomas, Testi, Silvia, Salmon, Eric, Santens, Patrick, Cras, Patrick, Vandenberghe, Rik, De Deyn, Peter Paul, Cruts, Marc, Van Broeckhoven, Christine, van der Zee, Julie, Dillen, Lubina, Van Langenhove, Tim, Philtjens, Stéphanie, Sleegers, Kristel, Corsmit, Ellen, Cruts, Marc, Van Broeckhoven, Christine, Engelborghs, Sebastiaan, De Deyn, Peter P., Cras, Patrick, Vandenbulcke, Mathieu, Borroni, Barbara, Padovani, Alessandro, Archetti, Silvana, Maetzler, Walter, Heneka, Michael T., Jessen, Frank, Kurzwelly, Delia, Sachtleben, Carmen, Miltenberger-Miltenyi, Gabriel, Pereira, Sónia, Firmo, Clara, Pimentel, José, Llado, Albert, Antonell, Anna, Gelpi, Ellen, Kinhult Ståhlbom, Anne, Thonberg, Håkan, Nennesmo, Inger, Börjesson-Hanson, Anne, Bagnoli, Silvia, Sorbi, Sandro, Santiago, Beatriz, Helena Ribeiro, Maria, Garret, Carolina, Pires, Paula, Frisoni, Giovanni, Zanetti, Orazio, Bonvicini, Cristian, Sarafov, Stayko, Tournev, Ivailo, Jordanova, Albena, Ströbel, Thomas, Mairer, Wolfgang, Matej, Radoslav, Parobkova, Eva, Danel, Adrian, Arzberger, Thomas, Maria Fabrizi, Gian, Testi, Silvia, Ferrari, Sergio, Cavallaro, Tiziana, Salmon, Eric

Get full text

Rare variants in IFFO1, DTNB, NLRC3 and SLC22A10 associate with Alzheimer's disease CSF profile of neuronal injury and inflammation by Neumann, Alexander, Küçükali, Fahri, Bos, Isabelle, Vos, Stephanie J B, Engelborghs, Sebastiaan, De Pooter, Tim, Joris, Geert, De Rijk, Peter, De Roeck, Ellen, Tsolaki, Magda, Verhey, Frans, Martinez-Lage, Pablo, Tainta, Mikel, Frisoni, Giovanni, Blin, Oliver, Richardson, Jill, Bordet, Régis, Scheltens, Philip, Popp, Julius, Peyratout, Gwendoline, Johannsen, Peter, Frölich, Lutz, Vandenberghe, Rik, Freund-Levi, Yvonne, Streffer, Johannes, Lovestone, Simon, Legido-Quigley, Cristina, Ten Kate, Mara, Barkhof, Frederik, Strazisar, Mojca, Zetterberg, Henrik, Bertram, Lars, Visser, Pieter Jelle, van Broeckhoven, Christine, Sleegers, Kristel

Get full text

Plasma Proteomic Biomarkers Relating to Alzheimer’s Disease: A Meta-Analysis Based on Our Own Studies by Shi, Liu, Buckley, Noel J., Bos, Isabelle, Engelborghs, Sebastiaan, Sleegers, Kristel, Frisoni, Giovanni B., Wallin, Anders, Lléo, Alberto, Popp, Julius, Martinez-Lage, Pablo, Legido-Quigley, Cristina, Barkhof, Frederik, Zetterberg, Henrik, Visser, Pieter Jelle, Bertram, Lars, Lovestone, Simon, Nevado-Holgado, Alejo J.

Get full text

Cerebrovascular risk factors do not contribute to genetic variance of cognitive function: the ERF study by Sleegers, K, de Koning, I, Aulchenko, Y S, van Rijn, M J E, Houben, M P W A, Croes, E A, van Swieten, J C, Oostra, B A, van Duijn, C M

Get full text

TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis by der Zee, Julie, Gijselinck, Ilse, Mossevelde, Sara, Perrone, Federica, Dillen, Lubina, Heeman, Bavo, Bäumer, Veerle, Engelborghs, Sebastiaan, Bleecker, Jan, Baets, Jonathan, Gelpi, Ellen, Rojas‐García, Ricardo, Clarimón, Jordi, Lleó, Alberto, Diehl‐Schmid, Janine, Alexopoulos, Panagiotis, Perneczky, Robert, Synofzik, Matthis, Just, Jennifer, Schöls, Ludger, Graff, Caroline, Thonberg, Håkan, Borroni, Barbara, Padovani, Alessandro, Jordanova, Albena, Sarafov, Stayko, Tournev, Ivailo, Mendonça, Alexandre, Miltenberger‐Miltényi, Gabriel, Simões do Couto, Frederico, Ramirez, Alfredo, Jessen, Frank, Heneka, Michael T., Gómez‐Tortosa, Estrella, Danek, Adrian, Cras, Patrick, Vandenberghe, Rik, Jonghe, Peter, Deyn, Peter P., Sleegers, Kristel, Cruts, Marc, Broeckhoven, Christine, Goeman, Johan, Nuytten, Dirk, Smets, Katrien, Robberecht, Wim, Damme, Philip Van, Bleecker, Jan De, Santens, Patrick, Dermaut, Bart, Versijpt, Jan, Michotte, Alex, Ivanoiu, Adrian, Deryck, Olivier, Bergmans, Bruno, Delbeck, Jean, Bruyland, Marc, Willems, Christiana, Salmon, Eric, Pastor, Pau, Ortega‐Cubero, Sara, Benussi, Luisa, Ghidoni, Roberta, Binetti, Giuliano, Hernández, Isabel, Boada, Mercè, Ruiz, Agustín, Sorbi, Sandro, Nacmias, Benedetta, Bagnoli, Silvia, Sorbi, Sandro, Sanchez‐Valle, Raquel, Llado, Albert, Santana, Isabel, Rosário Almeida, Maria, Frisoni, Giovanni B, Maetzler, Walter, Matej, Radoslav, Fraidakis, Matthew J., Kovacs, Gabor G., Fabrizi, Gian Maria, Testi, Silvia

Get full text

Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN‐derived networks and highlights causal links in Alzheimer's disease by Shi, Liu, Xu, Jin, Green, Rebecca, Wretlind, Asger, Homann, Jan, Buckley, Noel J., Tijms, Betty M., Vos, Stephanie J. B., Lill, Christina M., Kate, Mara ten, Engelborghs, Sebastiaan, Sleegers, Kristel, Frisoni, Giovanni B., Wallin, Anders, Lleó, Alberto, Popp, Julius, Martinez‐Lage, Pablo, Streffer, Johannes, Barkhof, Frederik, Zetterberg, Henrik, Visser, Pieter Jelle, Lovestone, Simon, Bertram, Lars, Nevado‐Holgado, Alejo J., Proitsi, Petroula, Legido‐Quigley, Cristina

Get full text

Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks by Zhang, Yuting, Ghose, Upamanyu, Buckley, Noel J, Engelborghs, Sebastiaan, Sleegers, Kristel, Frisoni, Giovanni B, Wallin, Anders, Lleó, Alberto, Popp, Julius, Martinez-Lage, Pablo, Legido-Quigley, Cristina, Barkhof, Frederik, Zetterberg, Henrik, Visser, Pieter Jelle, Bertram, Lars, Lovestone, Simon, Nevado-Holgado, Alejo J, Shi, Liu

Get full text