Search Results - Skouras, Stephanie M

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    Selective IRAK4 degradation, not kinase inhibition, blocks TLR-activated NF-Kb and p38 Signaling leading to broad cytokine inhibition

    Selective IRAK4 degradation, not kinase inhibition, blocks TLR-activated NF-Kb and p38 Signaling leading to broad cytokine inhibition by Skouras, Stephanie M, Massa, Virginia, Lurier, Emily, Hubeau, Cedric, Wang, Amy, Zheng, Xiaozhang, Sharma, Kirti, Walter, Dirk, Browne, Chris, Mayo, Michele, Fitzgerald, Michael, McDonald, Alice, Gollob, Jared, Mainolfi, Nello, Slavin, Anthony, Campbell, Veronica

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    Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases

    Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases by Zheng, Xiaozhang, Ji, Nan, Campbell, Veronica, Slavin, Anthony, Zhu, Xiao, Chen, Dapeng, Rong, Haojing, Enerson, Brad, Mayo, Michele, Sharma, Kirti, Browne, Chris M, Klaus, Christine R, Li, Haoran, Massa, Ginny, McDonald, Alice A, Shi, Yatao, Sintchak, Mike, Skouras, Stephanie, Walther, Dirk M, Yuan, Karen, Zhang, Yi, Kelleher, Joe, Liu, Guang, Luo, Xinbo, Mainolfi, Nello, Weiss, Matthew M

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