Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site

by Uprety, Rajendra, Che, Tao, Zaidi, Saheem A, Grinnell, Steven G, Varga, Balázs R, Faouzi, Abdelfattah, Slocum, Samuel T, Allaoa, Abdullah, Varadi, András, Nelson, Melissa, Bernhard, Sarah M, Kulko, Elizaveta, Le Rouzic, Valerie, Eans, Shainnel O, Simons, Chloe A, Hunkele, Amanda, Subrath, Joan, Pan, Ying Xian, Javitch, Jonathan A, McLaughlin, Jay P, Roth, Bryan L, Pasternak, Gavril W, Katritch, Vsevolod, Majumdar, Susruta
Published in eLife

Lyophilized Kratom Tea as a Therapeutic Option for Opioid Dependence

by Wilson, Lisa L., Harris, Hannah M., Eans, Shainnel O., Brice-Tutt, Ariana C., Cirino, Thomas J., Stacy, Heather M., Simons, Chloe A., León, Francisco, Sharma, Abhisheak, Boyer, Edward W., Avery, Bonnie A., McLaughlin, Jay P., McCurdy, Christopher R.
Published in Drug and alcohol dependence

Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal

by Wilson, Lisa L., Chakraborty, Soumen, Eans, Shainnel O., Cirino, Thomas J., Stacy, Heather M., Simons, Chloe A., Uprety, Rajendra, Majumdar, Susruta, McLaughlin, Jay P.
Published in Cellular and molecular neurobiology

Myelin regulatory factor is a target of individual and interactive effects of HIV-1 Tat and morphine in the striatum and pre-frontal cortex

by Flounlacker, Kelly M., Hahn, Yun Kyung, Xu, Ruqiang, Simons, Chloe A., Tian, Tao, Hauser, Kurt F., Knapp, Pamela E.
Published in Journal of neurovirology

Multifunctional opioid receptor agonism and antagonism by a novel macrocyclic tetrapeptide prevents reinstatement of morphine‐seeking behaviour

by Brice‐Tutt, Ariana C., Wilson, Lisa L., Eans, Shainnel O., Stacy, Heather M., Simons, Chloe A., Simpson, Grant G., Coleman, Jeremy S., Ferracane, Michael J., Aldrich, Jane V., McLaughlin, Jay P.
Published in British journal of pharmacology

Expression of Human Immunodeficiency Virus Transactivator of Transcription (HIV-Tat1-86) Protein Alters Nociceptive Processing that is Sensitive to Anti-Oxidant and Anti-Inflammato...

by Cirino, Thomas J., Alleyne, Amy R., Duarte, Vinicius, Figueroa, Ariana, Simons, Chloe A., Anceaume, Emet M., Kendrick, Justin, Wallman, Olivia, Eans, Shainnel O., Stacy, Heather M., Medina, Jessica M., McLaughlin, Jay P.
Published in Journal of neuroimmune pharmacology

A web-based, patient driven registry for Angelman syndrome: the global Angelman syndrome registry

by Napier, Kathryn R, Tones, Megan, Simons, Chloe, Heussler, Helen, Hunter, Adam A, Cross, Meagan, Bellgard, Matthew I
Published in Orphanet journal of rare diseases

The Cost of Raising Individuals with Fragile X or Chromosome 15 Imprinting Disorders in Australia

by Baker, Emma K., Arora, Sheena, Amor, David J., Date, Perrin, Cross, Meagan, O’Brien, James, Simons, Chloe, Rogers, Carolyn, Goodall, Stephen, Slee, Jennie, Cahir, Chris, Godler, David E.
Published in Journal of autism and developmental disorders

Caregivers Report on the Pathway to a Formal Diagnosis of Angelman Syndrome: A Comparison Across Genetic Etiologies within the Global Angelman Syndrome Registry

by Roche, Laura, Tones, Megan, Williams, Mark G., Cross, Meagan, Simons, Chloe, Heussler, Helen
Published in Advances in neurodevelopmental disorders

Defending Korea's peace island.(Agenda: ALSO IN THE NEWS THIS MONTH)

by Simons, Chloe
Published in New internationalist

Seasonal and long-term consequences of esca grapevine disease on stem xylem integrity

by Bortolami, Giovanni, Farolfi, Elena, Badel, Eric, Burlett, Regis, Cochard, Herve, Ferrer, Nathalie, King, Andrew, Lamarque, Laurent J, Lecomte, Pascal, Marchesseau-Marchal, Marie, Pouzoulet, Jerome, Torres-Ruiz, Jose M, Trueba, Santiago, Delzon, Sylvain, Gambetta, Gregory A, Delmas, Chloe E L
Published in Journal of experimental botany

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

by Lawson, Keith A, Sousa, Cristovão M, Zhang, Xiaoyu, Kim, Eiru, Akthar, Rummy, Caumanns, Joseph J, Yao, Yuxi, Mikolajewicz, Nicholas, Ross, Catherine, Brown, Kevin R, Zid, Abdelrahman Abou, Fan, Zi Peng, Hui, Shirley, Krall, Jordan A, Simons, Donald M, Slater, Chloe J, De Jesus, Victor, Tang, Lujia, Singh, Richa, Goldford, Joshua E, Martin, Sarah, Huang, Qian, Francis, Elizabeth A, Habsid, Andrea, Climie, Ryan, Tieu, David, Wei, Jiarun, Li, Ren, Tong, Amy Hin Yan, Aregger, Michael, Chan, Katherine S, Han, Hong, Wang, Xiaowei, Mero, Patricia, Brumell, John H, Finelli, Antonio, Ailles, Laurie, Bader, Gary, Smolen, Gromoslaw A, Kingsbury, Gillian A, Hart, Traver, Kung, Charles, Moffat, Jason
Published in Nature (London)

Community transmission of monkeypox in the United Kingdom, April to May 2022

by Vivancos, Roberto, Anderson, Charlotte, Blomquist, Paula, Balasegaram, Sooria, Bell, Anita, Bishop, Louise, Brown, Colin S, Chow, Yimmy, Edeghere, Obaghe, Florence, Isaac, Logan, Sarah, Manley, Petra, Crowe, William, McAuley, Andrew, Shankar, Ananda Giri, Mora-Peris, Borja, Paranthaman, Karthik, Prochazka, Mateo, Ryan, Cian, Simons, David, Vipond, Richard, Byers, Chloe, Watkins, Nicholas A, Welfare, Will, Whittaker, Elizabeth, Dewsnap, Claire, Wilson, Allegra, Young, Yvonne, Chand, Meera, Riley, Steven, Hopkins, Susan
Published in Euro surveillance : bulletin européen sur les maladies transmissibles

Identification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro

by Blankley, Simon, Graham, Christine M, Howes, Ashleigh, Bloom, Chloe I, Berry, Matthew P R, Chaussabel, Damien, Pascual, Virginia, Banchereau, Jacques, Lipman, Marc, O'Garra, Anne
Published in PloS one

Ecoregion-based conservation planning in the Mediterranean: dealing with large-scale heterogeneity

by Giakoumi, Sylvaine, Sini, Maria, Gerovasileiou, Vasilis, Mazor, Tessa, Beher, Jutta, Possingham, Hugh P, Abdulla, Ameer, Çinar, Melih Ertan, Dendrinos, Panagiotis, Gucu, Ali Cemal, Karamanlidis, Alexandros A, Rodic, Petra, Panayotidis, Panayotis, Taskin, Ergun, Jaklin, Andrej, Voultsiadou, Eleni, Webster, Chloë, Zenetos, Argyro, Katsanevakis, Stelios
Published in PloS one

Multimodal machine learning for modeling infant head circumference, mothers' milk composition, and their shared environment

by Becker, Martin, Fehr, Kelsey, Goguen, Stephanie, Miliku, Kozeta, Field, Catherine, Robertson, Bianca, Yonemitsu, Chloe, Bode, Lars, Simons, Elinor, Marshall, Jean, Dawod, Bassel, Mandhane, Piushkumar, Turvey, Stuart E, Moraes, Theo J, Subbarao, Padmaja, Rodriguez, Natalie, Aghaeepour, Nima, Azad, Meghan B
Published in Scientific reports

Home and Online Management and Evaluation of Blood Pressure (HOME BP) using a digital intervention in poorly controlled hypertension: randomised controlled trial

by McManus, Richard J, Little, Paul, Stuart, Beth, Raftery, James, Zhang, Jin, Zhu, Shihua, May, Carl R, Mair, Frances S, Smith, Peter, Band, Rebecca, Ogburn, Emma, Allen, Julie, Nuttall, Jacqui, Williams, Bryan, Yardley, Lucy, Jones, Adam, Hussain, Ajmal, LaLonde, Anna, Malik, Asim, Hernandez-Diaz, Basilio, Cranfield, Ben, Bobrow, Cathy, Keast, Christopher, Henderson, Clare, Henderson, Dan, Noble, Debbie, Williams, Edward, Mohri, Fatima, Dougall, Greig, Luckhurst, Heidi, Brown, Jan, Flett, Jennifer, Rutter, Heather, Thompson, Julian, Ramanan, Kanjhana, Madronal, Karen, Etherington, Katie, Tsoi, Kenney, Knox, Kyle, Amin, Laila, Hirst, Lisa, Allen, Lucy, Skellern, Luke, Gaw, Matthew, Prendergast, Matthew, Faisal, Muhammad, Moore, Patrick, Conley, Paul, Wilson, Penny, Zamir, Rebecca, Danson, Ruth, Lawes, Ruth, Cartwright, Simon, Doggett, Stephen, Sevenoaks, Tamsin, Watson, Tara, Talbot, Tess, Herbert, Thomas, Wright, Tony, Sharma, Vanshika, Telford, Vicki, Almashta, Zaid, Ali, Zishan, Claxton, Andy, Asante, Barbara, Weare, Becki, Mulvihill, Carole, Sherwood, Caroline, Roberts, Debbie, Qasim, Irene, King, Jill, Johal, Kam, Barnes, Katie, Bowden, Kelly-Marie, Peniket, Lara, Carnegie, Leann, Neale, Linda, Davey, Lisa, Bartlett, Liz, Smith, Louise, Clack, Lucy, Kay, Pam, Cutts, Rebecca, Pearse, Robert, Atkinson, Ruth, Barter, Sally, Mackie, Sally, Cook, Sandra, Elderfield, Sarah, Marchant, Stephanie, Wright, Stephanie, Keene, Sue, Smith, Sue, Stone, Tracy, Joyce, Tricia, Le Marechal, Trudie, Kettle, Vicky, Osborne, Victoria, Cubiss, Wendy, Bailey, Zoe
Published in BMJ (Online)

Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial

by Feig, Denice S, Donovan, Lois E, Corcoy, Rosa, Amiel, Stephanie A, Hunt, Katharine F, Asztalos, Elizabeth, Barrett, Jon F R, de Leiva, Alberto, Hod, Moshe, Jovanovic, Lois, Keely, Erin, McManus, Ruth, Hutton, Eileen K, Stewart, Zoe A, Wysocki, Tim, O'Brien, Robert, Kollman, Craig, Tomlinson, George, Murphy, Helen R, Grisoni, Jeannie, Byrne, Carolyn, Davenport, Katy, Neoh, Sandra, Gougeon, Claire, Oldford, Carolyn, Young, Catherine, Green, Louisa, Rossi, Benedetta, Rogers, Helen, Cleave, Barbara, Strom, Michelle, Adelantado, Juan María, Tundidor, Diana, Henry, Kathy, Morris, Damian, Rayman, Gerry, Fowler, Duncan, Mitchell, Susan, Rosier, Josephine, Temple, Rosemary, Turner, Jeremy, Hewapathirana, Niranjala, Piper, Leanne, Kudirka, Anne, Watson, Margaret, Bonomo, Matteo, Pintaudi, Basilio, Bertuzzi, Federico, Daniela, Giuseppina, Mion, Elena, Lowe, Julia, Halperin, Ilana, Rogowsky, Anna, Adib, Sapida, Carty, David, Crawford, Isobel, Mackenzie, Fiona, McInnes, Natalia, Smith, Ada, Stanton, Irene, Tazzeo, Tracy, Weisnagel, John, Jones, Nia, MacDougall, Malcolm, Chilton, Sharon, Scott, Eleanor, Endersby, Del, Novodorsky, Peter, Hudson, Sue, Nisbet, Chloe, Coolen, Jill, Baxendale, Darlene, Holt, Richard, Forbes, Jane, Martin, Nicki, Conway, Sharon, Egan, Aoife, Kirwin, Collette, Maresh, Michael, Kearney, Gretta, Quinn, Susan, Bilous, Rudy, Godbout, Ariane, Lubina, Alexandra, Jackson, Margaret, Paul, Emma, Taylor, Julie, Houlden, Robyn, Breen, Adriana, Banerjee, Anita, Reid, Anna, Singh, Claire, Newstead-Angel, Jill, Baxter, Janet, Philip, Sam, Murray, Lynne, Castorino, Kristin, Frase, Donna, Lou, Olivia, Pragnell, Marlon
Published in The Lancet (British edition)

From Cullowhee Creek to Conley: genome sequence and annotation of a cluster DJ Gordonia phage

by Andro, Mindy N, Cansler, Aj J, Conley, Olivia S, Cruz, Naidelyn O, Dionne, Joshua A, Edwards, Jordan I, Furtuna, Daniel, Green, Carlee J, Huber, Miriam, Hudson, Gunnar J, Humphries, Isabella R, Karazin, Amanda A, Mombille, Patrizia I, Pell, Montana M, Shickle, Gabriela, Shipp, Zahria J, Timmons, Chloe A, Trembush, Jasmine I, Turnmire, Cameron D, Yemofio, Naa Yemoley, Burleson, Mathew D, Gainey, Maria D
Published in Microbiology resource announcements

The global burden of tuberculosis: results from the Global Burden of Disease Study 2015

by Maddison, Emilie R, Mumford, John Everett, Barber, Ryan, Brown, Jonathan C, Wolock, Timothy M, Reitsma, Marissa, Ross, Jennifer M, Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbas, Kaja, Abera, Mubarek, Abera Hareri, Habtamu, Ahmed, Muktar, Alene, Kefyalew Addis, Alvis-Guzman, Nelson, Amo-Adjei, Joshua, Ansari, Hossein, Antonio, Carl Abelardo, Asayesh, Hamid, Atey, Tesfay Mehari, Atre, Sachin, Barac, Aleksandra, Beardsley, Justin, Bensenor, Isabela, Beyene, Addisu Shunu, Butt, Zahid Ahmad, Cardona, Pere-Joan, Dandona, Lalit, Dandona, Rakhi, Deribe, Kebede, Deribew, Amare, Ehrenkranz, Rebecca, El Sayed Zaki, Maysaa, Endries, Aman, Feyissa, Tesfaye R, Fischer, Florian, Gai, Ruoyan, Garcia-Basteiro, Alberto L, Gebrehiwot, Tsegaye Tewelde, Gesesew, Hailay, Getahun, Belete, Gona, Philimon, Goodridge, Amador, Haghparast-Bidgoli, Hassan, Hailu, Gessessew Bugssa, Hassen, Hamid Yimam, Horita, Nobuyuki, Jacobsen, Kathryn H, Jonas, Jost B, Kasaeian, Amir, Kedir, Muktar Sano, Kemmer, Laura, Khader, Yousef, Khang, Young-Ho, Khoja, Abdullah T, Koul, Parvaiz, Koyanagi, Ai, Krohn, Kristopher J, Kumar, G Anil, Magdy And El Razek, Hassan, Majdzadeh, Reza, Manyazewal, Tsegahun, Memish, Ziad, Mendoza, Walter, Mezgebe, Haftay Berhane, Mohammed, Shafiu, Ogbo, Felix Akpojene, Oh, In-Hwan, Oren, Eyal, Osgood-Zimmerman, Aaron, Pereira, David, Plass, Dietrich, Pourmalek, Farshad, Rafay, Anwar, Rahman, Mahfuzar, Ray, Sarah E, Safiri, Saeid, Sartorius, Benn, Shey, Muki, Shifti, Desalegn Markos, Shore, Hirbo, Singh, Jasvinder, Sreeramareddy, Chandrashekhar T, Swaminathan, Soumya, Swartz, Scott J, Tadese, Fentaw, Tegegne, Balewgizie Sileshi, Tessema, Belay, Topor-Madry, Roman, Ukwaja, Kingsley Nnanna, Uthman, Olalekan A., Vlassov, Vasiliy, Vollset, Stein Emil, Wakayo, Tolassa, Workicho, Abdulhalik, Yonemoto, Naohiro, Yotebieng, Marcel, Naghavi, Mohsen, Vos, Theo, Murray, Christopher JL
Published in The Lancet infectious diseases