Putative Origins of Cell-Free DNA in Humans: A Review of Active and Passive Nucleic Acid Release Mechanisms

by Grabuschnig, Stefan, Bronkhorst, Abel Jacobus, Holdenrieder, Stefan, Rosales Rodriguez, Ingund, Schliep, Klaus Peter, Schwendenwein, Daniel, Ungerer, Vida, Sensen, Christoph Wilhelm
Published in International journal of molecular sciences

Four distinct types of E.C. 1.2.1.30 enzymes can catalyze the reduction of carboxylic acids to aldehydes

by Stolterfoht, Holly, Schwendenwein, Daniel, Sensen, Christoph W., Rudroff, Florian, Winkler, Margit
Published in Journal of biotechnology

Identification of Key Residues for Enzymatic Carboxylate Reduction

by Stolterfoht, Holly, Steinkellner, Georg, Schwendenwein, Daniel, Pavkov-Keller, Tea, Gruber, Karl, Winkler, Margit
Published in Frontiers in microbiology

Chemo-Enzymatic Cascade for the Generation of Fragrance Aldehydes

by Schwendenwein, Daniel, Ressmann, Anna K., Entner, Marcello, Savic, Viktor, Winkler, Margit, Rudroff, Florian
Published in Catalysts

Circulating cell-free DNA is predominantly composed of retrotransposable elements and non-telomeric satellite DNA

by Grabuschnig, Stefan, Soh, Jung, Heidinger, Petra, Bachler, Thorsten, Hirschböck, Elisabeth, Rosales Rodriguez, Ingund, Schwendenwein, Daniel, Sensen, Christoph W.
Published in Journal of biotechnology

Design of inducible expression vectors for improved protein production in Ralstonia eutropha H16 derived host strains

by Gruber, Steffen, Schwendenwein, Daniel, Magomedova, Zalina, Thaler, Eva, Hagen, Jeremias, Schwab, Helmut, Heidinger, Petra
Published in Journal of biotechnology

Carboxylate reductases from fungal origin for the preparation of aldehyde fragrances

by Winkler, Margit, Schwendenwein, Daniel, Rudroff, Florian
Published in New biotechnology

Enzymes as Biodevelopers for Nano- And Micropatterned Bicomponent Biopolymer Thin Films

by Niegelhell, Katrin, Süßenbacher, Michael, Jammernegg, Katrin, Ganner, Thomas, Schwendenwein, Daniel, Schwab, Helmut, Stelzer, Franz, Plank, Harald, Spirk, Stefan
Published in Biomacromolecules

Evaluation of host-based molecular markers for the early detection of human sepsis

by Ullrich, Elisabeth, Heidinger, Petra, Soh, Jung, Villanova, Laura, Grabuschnig, Stefan, Bachler, Thorsten, Hirschböck, Elisabeth, Sánchez-Heredero, Sara, Ford, Barry, Sensen, Maria, Rosales Rodriguez, Ingund, Schwendenwein, Daniel, Neumeister, Peter, Zurl, Christoph J., Krause, Robert, Lorenz Khol, Johannes, Sensen, Christoph W.
Published in Journal of biotechnology

Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study

by Wiegers, Eveline, Sewalt, Charlie, De Keyser, Véronique, Kunzmann, Kevin, von Steinbüchel, Nicole, Wilson, Lindsay, Maas, Andrew I R, Ackerlund, Cecilia, Andelic, Nada, Auslands, Kaspars, Bartels, Ronald, Barzó, Pál, Bellander, Bo-Michael, Benali, Habib, Brazinova, Alexandra, Brorsson, Camilla, Caccioppola, Alessio, Carbonara, Marco, Castaño-León, Ana M, Chevallard, Giorgio, Chieregato, Arturo, Coles, Jonathan, Cooper, Jamie D, Correia, Marta, Depreitere, Bart, Dijkland, Simone, Đilvesi, Đula, Donoghue, Emma, Dulière, Guy-Loup, Esser, Patrick, Feigin, Valery L, Foks, Kelly, Frisvold, Shirin, Furmanov, Alex, Gagliardo, Pablo, Gantner, Dashiell, Glocker, Ben, Gomez, Pedro A, Gratz, Johannes, Gravesteijn, Benjamin, Grossi, Francesca, Haagsma, Juanita A., Haitsma, Iain, Helbok, Raimund, Helseth, Eirik, Huijben, Jilske, Jankowski, Stefan, Karan, Mladen, Kolias, Angelos G, Kompanje, Erwin, Kondziella, Daniel, Lagares, Alfonso, Lanyon, Linda, Lejeune, Aurelie, Levi, Leon, Lightfoot, Roger, Maegele, Marc, McMahon, Catherine, Muraleedharan, Visakh, Murray, Lynnette, Negru, Ancuta, Noirhomme, Quentin, Piippo-Karjalainen, Anna, Ples, Horia, Raj, Rahul, Real, Ruben, Rhodes, Jonathan, Roe, Cecilie, Rosand, Jonathan, Rosenthal, Guy, Rossi, Sandra, Rusnák, Martin, Sanchez-Porras, Renan, Schäfer, Nadine, Schoechl, Herbert, Schou, Rico Frederik, Schwendenwein, Elisabeth, Skandsen, Toril, Sorinola, Abayomi, Stewart, William, Synnot, Anneliese, Theadom, Alice, Thomas, Matt, Tibboel, Dick, Trapani, Tony, Van der Steen, Gregory, van Dijck, Jeroen T J M, Van Hecke, Wim, van Heugten, Caroline, van Wijk, Roel P J, Vande Vyvere, Thijs, Verheyden, Jan, Vulekovic, Petar, Williams, Guy, Wilson, Lindsay, Winzeck, Stefan, Younsi, Alexander, Zelinkova, Veronika, Ziverte, Agate, Zoerle, Tommaso
Published in Lancet neurology

Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury

by Gravesteijn, Benjamin Y., Lingsma, Hester F., Nelson, David, Steyerberg, Ewout W., Andreassen, Lasse, Anke, Audny, Audibert, Gérard, Barzó, Pál, Beauvais, Romuald, Bellander, Bo-Michael, Benali, Habib, Beretta, Luigi, Blaabjerg, Morten, Brazinova, Alexandra, Brooker, Joanne, Brorsson, Camilla, Bullinger, Monika, Lozano, Guillermo Carbayo, Chieregato, Arturo, Coburn, Mark, Dawes, Helen, Della Corte, Francesco, Đilvesi, Đula, Esser, Patrick, Martin Fabricius, Erzsébet Ezer, Feigin, Kelly Foks, Valery L., Gagliardo, Pablo, Gantner, Dashiell, Gao, Guoyi, Glocker, Ben, Gravesteijn, Benjamin, Grossi, Francesca, Gruen, Russell L., Helbok, Raimund, Jacobs, Bram, Ji-yao Jiang, Mike Jarrett, Karan, Mladen, Kolias, Angelos G., Kompanje, Erwin, Koraropoulos, Evgenios, Koskinen, Lars-Owe, Laureys, Steven, Legrand, Valerie, Lightfoot, Roger, Lingsma, Hester, Castaño-León, Ana M., Manley, Geoffrey, Maréchal, Hugues, McMahon, Catherine, Menovsky, Tomas, Mulazzi, Davide, Nair, Nandesh, Nieboer, Daan, Nyirádi, József, Oresic, Matej, Ortolano, Fabrizio, Palotie, Aarno, Parizel, Paul M., Pirinen, Matti, Polinder, Suzanne, Posti, Jussi P., Puybasset, Louis, Radoi, Andreea, Rhodes, Jonathan, Richardson, Sylvia, Richter, Sophie, Ripatti, Samuli, Rocka, Saulius, Roe, Cecilie, Rosenlund, Christina, Rossaint, Rolf, Sakowitz, Oliver, Sandor, Janos, Schoechl, Herbert, Schou, Rico Frederik, Schwendenwein, Elisabeth, Sewalt, Charlie, Stamatakis, Emmanuel, Stanworth, Simon, Ao, Braden Te, Tenovuo, Olli, Theadom, Alice, Tibboel, Dick, Vajkoczy, Peter, Vallance, Shirley, van der Naalt, Joukje, van Dijck, Jeroen T.J.M., van Essen, Thomas A., van Heugten, Caroline, Van Praag, Dominique, Vyvere, Thijs Vande, Vespa, Paul M., Voormolen, Daphne, Wang, Kevin K.W., Wiegers, Eveline, Winzeck, Stefan, Wolf, Stefan, Yang, Zhihui, Younsi, Alexander, Zelinkova, Veronika
Published in Journal of clinical epidemiology

Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): A Prospective Longitudinal Observational Study

by Maas, Andrew I.R, Menon, David K, Steyerberg, Ewout W, Citerio, Giuseppe, Lecky, Fiona, Manley, Geoffrey T, Hill, Sean, Legrand, Valerie, Sorgner, Annina
Published in Neurosurgery

Pathological Computed Tomography Features Associated With Adverse Outcomes After Mild Traumatic Brain Injury: A TRACK-TBI Study With External Validation in CENTER-TBI

by Yuh, Esther, Jain, Sonia, Sun, Xiaoying, Pisică, Dana, Harris, Mark H, Taylor, Sabrina R, Markowitz, Amy J, Mukherjee, Pratik, Verheyden, Jan, Giacino, Joseph T, Levin, Harvey, McCrea, Michael, Stein, Murray B, Temkin, Nancy R, Diaz-Arrastia, Ramon, Robertson, Claudia, Lingsma, Hester F, Okonkwo, David O, Maas, Andrew I. R, Manley, Geoffrey T, Andelic, Nada, Andreassen, Lasse, Anke, Audny Gabriele Wagner, Frisvold, Shirin, Helseth, Eirik, Røe, Cecilie, Røise, Olav, Skandsen, Toril, Vik, Anne, Åkerlund, Cecilia, Amrein, Krisztina, Antoni, Anna, Audibert, Gerard, Azouvi, Philippe, Azzolini, Maria luisa, Bartels, Ronald, Barzo, Pal, Beauvais, Romuald, Beer, Ronny, Bellander, Bo-michael, Belli, Antonio, Benali, Habib, Berardino, Maurizio, Beretta, Luigi, Blaabjerg, Morten, Bragge, Peter, Brazinova, Alexandra, Brinck, Vibeke, Brooker, Joanne, Brorsson, Camilla, Buki, Andras, Bullinger, Monika, Cabeleira, Manuel, Caccioppola, Alessio, Calappi, Emiliana, Calvi, Maria rosa
Published in JAMA neurology

Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury

by Mikolic, Ana, van Klaveren, David, Oude Groeniger, Joost, Wiegers, E, Lingsma, Hester F, Zeldovich, Marina, von Steinbüchel, Nicole, Maas, Andrew I.R, Roeters van Lennep, Jeanine, Polinder, Suzanne, Andelic, Nada, Andreassen, Lasse, Anke, Audny, Frisvold, Shirin, Helseth, Eirik, Røe, Cecilie, Røise, Olav, Skandsen, Toril, Vik, Anne, Åkerlund, Cecilia, Amrein, Krisztina
Published in Journal of neurotrauma

Effect of frailty on 6-month outcome after traumatic brain injury: a multicentre cohort study with external validation

by Graziano, Francesca, Jain, Sonia, Sun, Xiaoying, Markowitz, Amy J, Andelic, Nada, Azouvi, Philippe, Beer, Ronny, Berardino, Maurizio, Bragge, Peter, Buki, Andras, Cabeleira, Manuel, Carbayo Lozano, Guillermo, Cavallo, Simona, Chevallard, Giorgio, Clusmann, Hans, Coburn, Mark Steven, Coles, Jonathan, Correia, Marta, Covic, Amra, Curry, Nicola, Czeiter, Endre, Dahyot-Fizelier, Claire, Degos, Vincent, Esser, Patrick, Frisvold, Shirin, Furmanov, Alex, Gagliardo, Pablo, Gantner, Dashiell, Giga, Lelde, Glocker, Ben, Gomez, Pedro A., Gratz, Johannes, Gravesteijn, Benjamin, Helbok, Raimund, Jankowski, Stefan, Karan, Mladen, Manara, Alex, Maréchal, Hugues, McFadyen, Charles, McMahon, Catherine, Mikolic, Ana, Nyirádi, József, Perera, Natascha, Perlbarg, Vincent, Persona, Paolo, Pirinen, Matti, Pomposo, Inigo, Posti, Jussi P., Puybasset, Louis, Radoi, Andreea, Raj, Rahul, Rehorčíková, Veronika, Rhodes, Jonathan, Rosenthal, Guy, Sandor, Janos, Schäfer, Nadine, Schoonman, Guus, Singh, Ranjit D., Skandsen, Toril, Sorinola, Abayomi, Stewart, William, Steyerberg, Ewout W., Sundström, Nina, Theadom, Alice, Thomas, Matt, Tibboel, Dick, Trapani, Tony, van der Jagt, Mathieu, van der Naalt, Joukje, Van der Steen, Gregory, van Dijck, Jeroen T.J.M., van Erp, Inge A., Van Hecke, Wim, Vega, Emmanuel, Verheyden, Jan, Vik, Anne, Vilcinis, Rimantas, Volovici, Victor, von Steinbüchel, Nicole, Wang, Kevin K.W., Zeiler, Frederick A., Corrigan, John, Feeser, Venkata, Foreman, Brandon, Giacino, Joseph, Gonzalez, Luis, Grandhi, Ramesh, Keene, C. Dirk, Kitagawa, Ryan, McCrea, Michael, Noel, Florence, Nolan, Amber, Palacios, Eva, Perl, Daniel, Rabinowitz, Miri, Rosenthal, Eric, Sandsmark, Danielle, Schneider, Andrea, Schnyer, David, Stein, Murray
Published in Lancet neurology

Fluid balance and outcome in critically ill patients with traumatic brain injury (CENTER-TBI and OzENTER-TBI): a prospective, multicentre, comparative effectiveness study

by Frisvold, Shirin, Menon, David Krishna, Moore, Elizabeth Madeleine, Steyerberg, Ewout Willem, van der Jagt, Mathieu, Cooper, Jamie D., Schoechl, Herbert, Van Praag, Dominique, Maas, Andrew I.R., Vande Vyvere, Thijs, Depreitere, Bart, Van Hecke, Wim, Ghuysen, Alexandre, Gao, Guoyi, Jiang, Ji-yao, Fabricius, Martin, Raj, Rahul, Pirinen, Matti, Audibert, Gérard, Degos, Vincent, Benali, Habib, Galanaud, Damien, Legrand, Valerie, Dahyot-Fizelier, Claire, Kowark, Ana, Vajkoczy, Peter, Maegele, Marc, Gratz, Johannes, Bullinger, Monika, Younsi, Alexander, Sakowitz, Oliver, Melegh, Béla, Sorinola, Abayomi, Kovács, Noémi, Nyirádi, József, Amrein, Krisztina, Azzolini, Maria Luisa, Stocchetti, Nino, Carbonara, Marco, Citerio, Giuseppe, Chieregato, Arturo, Chevallard, Giorgio, Della Corte, Francesco, Rossi, Sandra, Tamosuitis, Tomas, Rocka, Saulius, Steyerberg, Ewout W., Kompanje, Erwin, Timmers, Marjolijn, Haitsma, Iain, van der Jagt, Mathieu, Voormolen, Daphne, Wiegers, Eveline, Polinder, Suzanne, Tibboel, Dick, van Wijk, Roel, van Dijck, Jeroen T.J.M., Schoonman, Guus, Te Ao, Braden, Andelic, Nada, Frisvold, Shirin, Vik, Anne, Ples, Horia, Vulekovic, Peter, Karan, Mladen, Golubovic, Jagoš, Taylor, Mark Steven, Majdan, Marek, Sahuquillo, Juan, Radoi, Andreea, Lanyon, Linda, George, Pradeep, Muraleedharan, Visakh, Ackerlund, Cecilia, Koskinen, Lars-Owe, Sundström, Nina, Manara, Alex, Coles, Jonathan, Stamatakis, Emmanuel, Williams, Guy, Ercole, Ari, Dixit, Abhishek, Newcombe, Virginia, McFadyen, Charles, Adams, Hadie, McMahon, Catherine, Rueckert, Daniel, Esser, Patrick, van Heugten, Caroline, Stanworth, Simon, Otesile, Olubukola, Lightfoot, Roger, Horton, Lindsay, Rosand, Jonathan, Wang, Kevin K.W., Yang, Zhihui, Gruen, Russell L., Cameron, Peter, Varma, Dinesh, Jordan, Andrea
Published in Lancet neurology

Clustering identifies endotypes of traumatic brain injury in an intensive care cohort: a CENTER-TBI study

by Steyerberg, Ewout W., Ercole, Ari, Andreassen, Lasse, Anke, Audny, Audibert, Gérard, Barzó, Pál, Beauvais, Romuald, Bellander, Bo-Michael, Benali, Habib, Beretta, Luigi, Blaabjerg, Morten, Brazinova, Alexandra, Brooker, Joanne, Brorsson, Camilla, Bullinger, Monika, Calappi, Emiliana, Lozano, Guillermo Carbayo, Citerio, Giuseppe, Dawes, Helen, De Keyser, Véronique, Corte, Francesco Della, Depreitere, Bart, Dixit, Abhishek, Dulière, GuyLoup, Fabricius, Martin, Feigin, Valery L., Galanaud, Damien, George, Pradeep, Gomez, Pedro A., Gravesteijn, Benjamin, Grossi, Francesca, Gupta, Deepak, Haagsma, Juanita A., Helseth, Eirik, Horton, Lindsay, Jacobs, Bram, Jankowski, Stefan, Jarrett, Mike, Jones, Kelly, Kolias, Angelos G., Koskinen, LarsOwe, Kowark, Ana, Lanyon, Linda, Lecky, Fiona, Levi, Leon, Lingsma, Hester, Maas, Andrew I. R., Majdan, Marek, Martino, Costanza, Mattern, Julia, Melegh, Béla, Menon, David, Menovsky, Tomas, Mikolic, Ana, Muraleedharan, Visakh, Murray, Lynnette, Nyirádi, József, Ortolano, Fabrizio, Perlbarg, Vincent, Persona, Paolo, Pirinen, Matti, Ples, Horia, Polinder, Suzanne, Puybasset, Louis, Radoi, Andreea, Raj, Rahul, Roise, Olav, Rosand, Jonathan, Rosenfeld, Jeffrey V., Rosenthal, Guy, Rueckert, Daniel, Sahuquillo, Juan, SanchezPorras, Renan, Sandor, Janos, Schäfer, Nadine, Schmidt, Silke, Schoechl, Herbert, Schou, Rico Frederik, Singh, Ranjit D., Smielewski, Peter, Stewart, William, Taylor, Mark Steven, Tenovuo, Olli, Thomas, Matt, Tibboel, Dick, Tudora, Cristina Maria, van Dijck, Jeroen T. J. M., van Veen, Ernest, Vyvere, Thijs Vande, van Wijk, Roel P. J., Vargiolu, Alessia, Velt, Kimberley, Verheyden, Jan, Vik, Anne, Volovici, Victor, Wang, Kevin K. W., Wolf, Stefan, Zeiler, Frederick A., Ziverte, Agate, Zoerle, Tommaso
Published in Critical care (London, England)

Serum metabolome associated with severity of acute traumatic brain injury

by Thomas, Ilias, Dickens, Alex M, Posti, Jussi P, Czeiter, Endre, Duberg, Daniel, Sinioja, Tim, Kråkström, Matilda, Retel Helmrich, Isabel R A, Wang, Kevin K W, Maas, Andrew I R, Steyerberg, Ewout W, Menon, David K, Tenovuo, Olli, Hyötyläinen, Tuulia, Büki, András, Orešič, Matej
Published in Nature communications

Surgery versus conservative treatment for traumatic acute subdural haematoma: a prospective, multicentre, observational, comparative effectiveness study

by Lingsma, Hester F, Ribbers, Gerard M, Hutchinson, Peter, Åkerlund, Cecilia, Amrein, Krisztina, Anke, Audny, Audibert, Gérard, Azzolini, Maria Luisa, Bartels, Ronald, Barzó, Pál, Bellander, Bo-Michael, Benali, Habib, Beretta, Luigi, Blaabjerg, Morten, Brazinova, Alexandra, Brinck, Vibeke, Brooker, Joanne, Bullinger, Monika, Caccioppola, Alessio, Calappi, Emiliana, Castaño-León, Ana M., Chieregato, Arturo, Czosnyka, Marek, De Keyser, Véronique, Della Corte, Francesco, Dixit, Abhishek, Donoghue, Emma, Dreier, Jens, Ezer, Erzsébet, Fabricius, Martin, Feigin, Valery L., Frisvold, Shirin, Gomez, Pedro A., Grossi, Francesca, Haagsma, Juanita A., Helseth, Eirik, Jankowski, Stefan, Jarrett, Mike, Jiang, Ji-yao, Johnson, Faye, Kondziella, Daniel, Lagares, Alfonso, Ledoux, Didier, Lefering, Rolf, Legrand, Valerie, Lejeune, Aurelie, Lightfoot, Roger, Maegele, Marc, Majdan, Marek, Maréchal, Hugues, Mattern, Julia, Melegh, Béla, Menovsky, Tomas, Mikolic, Ana, Muraleedharan, Visakh, Ortolano, Fabrizio, Payen, Jean-François, Perlbarg, Vincent, Pirinen, Matti, Polinder, Suzanne, Pomposo, Inigo, Posti, Jussi P., Rădoi, Andreea, Ragauskas, Arminas, Rehorčíková, Veronika, Richardson, Sylvia, Ripatti, Samuli, Rocka, Saulius, Rosand, Jonathan, Rosenthal, Guy, Sandor, Janos, Schäfer, Nadine, Schoonman, Guus, Skandsen, Toril, Smielewski, Peter, Sorinola, Abayomi, Kowark, Ana, Stewart, William, Tamás, Viktória, Taylor, Mark Steven, Tenovuo, Olli, Tibboel, Dick, van der Naalt, Joukje, van Dijck, Jeroen T.J.M., Van Hecke, Wim, van Heugten, Caroline, Van Veen, Ernest, van Wijk, Roel, Vande Vyvere, Thijs, Verheyden, Jan, Vespa, Paul M., Vulekovic, Petar, Wang, Kevin K.W., Wiegers, Eveline, Winzeck, Stefan, Wolf, Stefan, Yang, Zhihui, Ylén, Peter, Ziverte, Agate, Zoerle, Tommaso
Published in Lancet neurology

Occurrence and timing of withdrawal of life-sustaining measures in traumatic brain injury patients: a CENTER-TBI study

by van Veen, Ernest, van der Jagt, Mathieu, Citerio, Giuseppe, Stocchetti, Nino, Gommers, Diederik, Burdorf, Alex, Menon, David K., Maas, Andrew I. R., Kompanje, Erwin J. O., Lingsma, Hester F.
Published in Intensive care medicine