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Structure-Activity relationships of replacements for the triazolopyridazine of Anti-Cryptosporidium lead SLU-2633
by
Oboh, Edmund
,
Teixeira, José E.
,
Schubert, Tanner J.
,
Maribona, Adriana S.
,
Denman, Brylon N.
,
Patel, Radhika
,
Huston, Christopher D.
,
Meyers, Marvin J.
Published in
Bioorganic & medicinal chemistry
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Structure–Activity Relationship Studies of the Aryl Acetamide Triazolopyridazines against Cryptosporidium Reveals Remarkable Role of Fluorine
by
Schubert, Tanner J.
,
Oboh, Edmund
,
Peek, Hannah
,
Philo, Emily
,
Teixeira, José E.
,
Stebbins, Erin E.
,
Miller, Peter
,
Oliva, Jonathan
,
Sverdrup, Francis M.
,
Griggs, David W.
,
Huston, Christopher D.
,
Meyers, Marvin J.
Published in
Journal of medicinal chemistry
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Optimization of the Urea Linker of Triazolopyridazine MMV665917 Results in a New Anticryptosporidial Lead with Improved Potency and Predicted hERG Safety Margin
by
Oboh, Edmund
,
Schubert, Tanner J
,
Teixeira, Jose E
,
Stebbins, Erin E
,
Miller, Peter
,
Philo, Emily
,
Thakellapalli, Haresh
,
Campbell, Scott D
,
Griggs, David W
,
Huston, Christopher D
,
Meyers, Marvin J
Published in
Journal of medicinal chemistry
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Journal Title
Journal Of Medicinal Chemistry
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Bioorganic & Medicinal Chemistry
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Subjects
Structure-Activity Relationship
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Antiprotozoal Agents - Pharmacology
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2
Chemistry, Medicinal
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Cryptosporidiosis - Drug Therapy
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Cryptosporidium
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2
Humans
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Life Sciences & Biomedicine
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Pharmacology & Pharmacy
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Science & Technology
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[1, 2, 4]Triazolo[4, 3-B]Pyridazine
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Animals
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Anticryptosporidial
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Antiparasitic
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Antiprotozoal Agents - Chemical Synthesis
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Antiprotozoal Agents - Chemistry
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Cell Line
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Child
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Cryptosporidiosis
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Cryptosporidium - Drug Effects
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Diarrhea
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Acs Crkn Legacy Archives
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American Chemical Society:jisc Collections:american Chemical Society Read & Publish Agreement 2022-2024 (Reading List)
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Science Citation Index Expanded (Web Of Science)
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Elsevier Sciencedirect Journals
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Sciencedirect Journals
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Backfile Package - Organic Chemistry (Legacy) [Yco]
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