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Search Results - Roth, Sharin E
Search Results - Roth, Sharin E
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Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors
by
Woodhead, Jeffrey L
,
Brock, William J
,
Roth, Sharin E
,
Shoaf, Susan E
,
Brouwer, Kim L R
,
Church, Rachel
,
Grammatopoulos, Tom N
,
Stiles, Linsey
,
Siler, Scott Q
,
Howell, Brett A
,
Mosedale, Merrie
,
Watkins, Paul B
,
Shoda, Lisl K M
Published in
Toxicological sciences
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Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease
by
Bezençon, Jacqueline
,
Beaudoin, James J
,
Ito, Katsuaki
,
Fu, Dong
,
Roth, Sharin E
,
Brock, William J
,
Brouwer, Kim L R
Published in
Drug metabolism and disposition
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Bile Acids as Potential Biomarkers to Assess Liver Impairment in Polycystic Kidney Disease
by
Brock, William J.
,
Beaudoin, James J.
,
Slizgi, Jason R.
,
Su, Mingming
,
Jia, Wei
,
Roth, Sharin E.
,
Brouwer, Kim L. R.
Published in
International journal of toxicology
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Next‐Generation DILI Biomarkers: Prioritization of Biomarkers for Qualification and Best Practices for Biospecimen Collection in Drug Development
by
Roth, Sharin E.
,
Avigan, Mark I.
,
Bourdet, David
,
Brott, David
,
Church, Rachel
,
Dash, Ajit
,
Keller, Douglas
,
Sherratt, Philip
,
Watkins, Paul B.
,
Westcott‐Baker, Lucas
,
Lentini, Silvia
,
Merz, Michael
,
Ramaiah, Lila
,
Ramaiah, Shashi K.
,
Stanley, Ann Marie
,
Marcinak, John
Published in
Clinical pharmacology and therapeutics
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miR-122 Release in Exosomes Precedes Overt Tolvaptan-Induced Necrosis in a Primary Human Hepatocyte Micropatterned Coculture Model
by
Mosedale, Merrie
,
Eaddy, J Scott
,
Trask, O Joseph
,
Holman, Natalie S
,
Wolf, Kristina K
,
LeCluyse, Edward
,
Ware, Brenton R
,
Khetani, Salman R
,
Lu, Jingtao
,
Brock, William J
,
Roth, Sharin E
,
Watkins, Paul B
Published in
Toxicological sciences
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Altered Hepatobiliary Disposition of Tolvaptan and Selected Tolvaptan Metabolites in a Rodent Model of Polycystic Kidney Disease
by
Beaudoin, James J
,
Bezençon, Jacqueline
,
Cao, Yanguang
,
Mizuno, Katsuhiko
,
Roth, Sharin E
,
Brock, William J
,
Brouwer, Kim L R
Published in
Drug metabolism and disposition
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Simultaneous quantitation of delamanid (OPC-67683) and its eight metabolites in human plasma using UHPLC–MS/MS
by
Meng, Min
,
Smith, Benjamin
,
Johnston, Brad
,
Carter, Spencer
,
Brisson, Jerry
,
Roth, Sharin E.
Published in
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
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Editor's Highlight: Candidate Risk Factors and Mechanisms for Tolvaptan-Induced Liver Injury Are Identified Using a Collaborative Cross Approach
by
Mosedale, Merrie
,
Kim, Yunjung
,
Brock, William J
,
Roth, Sharin E
,
Wiltshire, Tim
,
Eaddy, J Scott
,
Keele, Gregory R
,
Corty, Robert W
,
Xie, Yuying
,
Valdar, William
,
Watkins, Paul B
Published in
Toxicological sciences
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Candidate Risk Factors and Mechanisms for Tolvaptan-Induced Liver Injury Are Identified Using a Collaborative Cross Approach
by
Mosedale, Merrie
,
Kim, Yunjung
,
Brock, William J.
,
Roth, Sharin E.
,
Wiltshire, Tim
,
Scott Eaddy, J.
,
Keele, Gregory R.
,
Corty, Robert W.
,
Xie, Yuying
,
Valdar, William
,
Watkins, Paul B.
Published in
Toxicological sciences
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Soluble Urokinase Plasminogen Activator Receptor and Decline in Kidney Function in Autosomal Dominant Polycystic Kidney Disease
by
Hayek, Salim S
,
Landsittel, Douglas P
,
Wei, Changli
,
Zeier, Martin
,
Yu, Alan S L
,
Torres, Vicente E
,
Roth, Sharin
,
Pao, Christina S
,
Reiser, Jochen
Published in
Journal of the American Society of Nephrology
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