Quinolines as a novel structural class of potent and selective PDE4 inhibitors: Optimisation for oral administration by Lunniss, Christopher J., Cooper, Anthony W.J., Eldred, Colin D., Kranz, Michael, Lindvall, Mika, Lucas, Fiona S., Neu, Margarete, Preston, Alex G.S., Ranshaw, Lisa E., Redgrave, Alison J., Ed Robinson, J., Shipley, Tracy J., Solanke, Yemisi E., Somers, Don O., Wiseman, Joanne O.

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The design of potent, non-peptidic inhibitors of hepatitis C protease by Andrews, David M., Chaignot, Helene M., Coomber, Barry A., Dowle, Mike D., Lucy Hind, S., Johnson, Martin R., Jones, Paul S., Mills, Gail, Patikis, Angela, Pateman, Tony J., Ed Robinson, J., Slater, Martin J., Trivedi, Naimisha

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Pyrrolidine-5,5-trans-lactams. 5. Pharmacokinetic Optimization of Inhibitors of Hepatitis C Virus NS3/4A Protease by Andrews, David M, Barnes, Michael C, Dowle, Mike D, Hind, S. Lucy, Johnson, Martin R, Jones, Paul S, Mills, Gail, Patikis, Angela, Pateman, Tony J, Redfern, Tracy J, Robinson, J. Ed, Slater, Martin J, Trivedi, Naimisha

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Pyrrolidine-5,5-trans-lactams. 1. Synthesis and Incorporation into Inhibitors of Hepatitis C Virus NS3/4A Protease by Andrews, David M, Carey, Seb J, Chaignot, Helene, Coomber, Barry A, Gray, Norman M, Hind, S. Lucy, Jones, Paul S, Mills, Gail, Robinson, J. Ed, Slater, Martin J

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Pyrrolidine-5,5-trans-lactams. 2. The Use of X-ray Crystal Structure Data in the Optimization of P3 and P4 Substituents by Andrews, David M, Chaignot, Helene, Coomber, Barry A, Good, Andrew C, Hind, S. Lucy, Johnson, Martin R, Jones, Paul S, Mills, Gail, Robinson, J. Ed, Skarzynski, Tadeusz, Slater, Martin J, Somers, Donald O'N

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Sialidase inhibitors related to zanamivir: Synthesis and biological evaluation of 4H-pyran 6-ether and ketone by Smith, Paul W., Robinson, J.Ed, Evans, Derek N., Sollis, Steven L., Howes, Peter D., Trivedi, Naimisha, Bethell, Richard C.

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Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease by Hill, Rebecca M., Kuijper, Sanne, Lindsey, Janet C., Petrie, Kevin, Schwalbe, Ed C., Barker, Karen, Boult, Jessica K.R., Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra L., Poon, Evon, Robinson, Simon P., Ruddle, Ruth, Raynaud, Florence I., Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah Leigh, Crosier, Stephen, Ellison, David W., Wharton, Stephen B., Robson, Keith, Michalski, Antony, Hargrave, Darren, Jacques, Thomas S., Pizer, Barry, Bailey, Simon, Swartling, Fredrik J., Weiss, William A., Chesler, Louis, Clifford, Steven C.

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Efficacy and safety of the proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab among high cardiovascular risk patients on maximally tolerated statin therapy: The ODY... by Kereiakes, Dean J., MD, FACC, FSCAI, Robinson, Jennifer G., MD, MPH, Cannon, Christopher P., MD, Lorenzato, Christelle, MSc, Pordy, Robert, MD, Chaudhari, Umesh, MD, Colhoun, Helen M., MD, MFPHM, FRCP(Ed)

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A brief introduction to mixed effects modelling and multi-model inference in ecology by Harrison, Xavier A, Donaldson, Lynda, Correa-Cano, Maria Eugenia, Evans, Julian, Fisher, David N, Goodwin, Cecily E D, Robinson, Beth S, Hodgson, David J, Inger, Richard

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Accurate and Reliable Prediction of Relative Ligand Binding Potency in Prospective Drug Discovery by Way of a Modern Free-Energy Calculation Protocol and Force Field by Wang, Lingle, Wu, Yujie, Deng, Yuqing, Kim, Byungchan, Pierce, Levi, Krilov, Goran, Lupyan, Dmitry, Robinson, Shaughnessy, Dahlgren, Markus K, Greenwood, Jeremy, Romero, Donna L, Masse, Craig, Knight, Jennifer L, Steinbrecher, Thomas, Beuming, Thijs, Damm, Wolfgang, Harder, Ed, Sherman, Woody, Brewer, Mark, Wester, Ron, Murcko, Mark, Frye, Leah, Farid, Ramy, Lin, Teng, Mobley, David L, Jorgensen, William L, Berne, Bruce J, Friesner, Richard A, Abel, Robert

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The effect of heat treatment on precipitation in the Cu-Ni-Al alloy Hiduron® 130 by Christofidou, Katerina A., Robinson, K. Jennifer, Mignanelli, Paul M., Pickering, Ed J., Jones, Nicholas G., Stone, Howard J.

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SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids by Reimer, Katharina C., Nagai, James S., Varghese, Finny S., Overheul, Gijs J., Roverts, Rona, Willemsen, Brigith, Beukenboom, Marcel, Dunnen, Wilfred den, Triana, Sergio H., Timm, Marie-Cherelle, van den Berge, Bartholomeus T., Nlandu, Quincy, Heijnert, Joelle, Bindels, Eric M.J., Hoogenboezem, Remco M., Mooren, Fieke, Kuppe, Christoph, Grünberg, Katrien, Steenbergen, Eric J., Czogalla, Jan, Sommerdijk, Nico, Akiva, Anat, Boor, Peter, Huber, Tobias B., Bar-David, Elad, Barr, Haim, Boby, Melissa L., Borden, Bruce, Bowman, Gregory R., Brun, Juliane, BVNBS, Sarma, Carbery, Anna, Chernychenko, Eugene, Clyde, Austin, Coffland, Joseph E., Cole, Jason, Cox, Lisa, Dudgeon, Tim, Dunnett, Louise, Erez, Noam, Fate, Gwen, Ferrins, Lori, Foster, Richard, Foster, Holly, Gabizon, Ronen, Gawriljuk, Victor O., Gehrtz, Paul, Gileadi, Carina, Giroud, Charline, Glen, Robert, Gorichko, Marian, Griffen, Ed J., Heer, Jag, Hill, Michelle, Horrell, Sam, Jajack, Andrew, De Jonghe, Steven, Kantsadi, Anastassia L., Koekemoer, Lizbe, Lee, Alpha A., Lefker, Bruce A., Macdonald, Hannah Bruce, Maclean, Beth, McCorkindale, Willam, McGovern, Briana L., Michurin, Oleg, Morris, Aaron, Morris, Garret M., Neyts, Johan, Oliva, Glaucius, Overheul, Gijs J., Owen, David, Psenak, Vladimir, Pai, Ruby, Paran, Nir, Perry, Benjamin, Pingle, Maneesh, Politi, Boaz, Powell, Ailsa, Puni, Reut, Resnick, Efrat, Rosales, Romel, Schofield, Chris, Shafeev, Mikhail, Sittner, Assa, Skyner, Rachael, Spencer, John, Tamir, Hadas, Tennant, Rachael, Tumber, Anthony, van Rij, Ronald P., Voelz, Vincent, Volkamer, Andra, von Delft, Annette, White, Kris M., Wright, Nathan, Zidane, Hadeer, Costa, Ivan G., Schneider, Rebekka K., Smeets, Bart

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Cognitive impairment in coeliac disease improves on a gluten‐free diet and correlates with histological and serological indices of disease severity by Lichtwark, I. T., Newnham, E. D., Robinson, S. R., Shepherd, S. J., Hosking, P., Gibson, P. R., Yelland, G. W.

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Dialysis initiation, modality choice, access, and prescription: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference by Chan, Christopher T., Blankestijn, Peter J., Dember, Laura M., Gallieni, Maurizio, Harris, David C.H., Lok, Charmaine E., Mehrotra, Rajnish, Stevens, Paul E., Wang, Angela Yee-Moon, Cheung, Michael, Wheeler, David C., Winkelmayer, Wolfgang C., Pollock, Carol A., Abu-Alfa, Ali K., Bargman, Joanne M., Bleyer, Anthony J., Brown, Edwina A., Davenport, Andrew, Davies, Simon J., Finkelstein, Frederic O., Flythe, Jennifer E., Goffin, Eric, Golper, Thomas A., Gómez, Rafael, Hamano, Takayuki, Hecking, Manfred, Heimbürger, Olof, Hole, Barnaby, Hothi, Daljit K., Ikizler, T. Alp, Isaka, Yoshitaka, Iseki, Kunitoshi, Jha, Vivekanand, Kawanishi, Hideki, Kerr, Peter G., Komenda, Paul, Kovesdy, Csaba P., Lacson, Ed, Laville, Maurice, Lee, Jung Pyo, Lerma, Edgar V., Levin, Nathan W., Lichodziejewska-Niemierko, Monika, Liew, Adrian, Lindley, Elizabeth, Lockridge, Robert S., Madero, Magdalena, Massy, Ziad A., McCann, Linda, Meyer, Klemens B., Morton, Rachael L., Nadeau-Fredette, Annie-Claire, Okada, Hirokazu, Perez, Jose, Perl, Jeff, Polkinghorne, Kevan R., Riella, Miguel C., Robinson, Bruce M., Rocco, Michael V., Rosansky, Steven J., Rotmans, Joris I., Fernanda Slon Roblero, María, Tangri, Navdeep, Tonelli, Marcello, Tong, Allison, Tsukamoto, Yusuke, Tungsanga, Kriang, Vachharajani, Tushar J., van Loon, Ismay, Watnick, Suzanne, Weiner, Daniel E., Wilkie, Martin, Zakharova, Elena

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Incidence, aetiology, and sequelae of viral meningitis in UK adults: a multicentre prospective observational cohort study by McGill, Fiona, Griffiths, Michael J, Bonnett, Laura J, Geretti, Anna Maria, Michael, Benedict D, Beeching, Nicholas J, McKee, David, Scarlett, Paula, Hart, Ian J, Mutton, Kenneth J, Jung, Agam, Adan, Guleed, Gummery, Alison, Sulaiman, Wan Aliaa Wan, Ennis, Katherine, Martin, Antony P, Haycox, Alan, Miller, Alastair, Solomon, Tom, Adedeji, Adekola, Katharine, Ajdukiewicz, David, Birkenhead, Thomas, Blanchard, Antony, Cadwgan, David, Chadwick, John, Cheesbrough, Richard, Cooke, John, Croall, Iain, Crossingham, James, Dunbar, Simon, Ellis, Camelia, Faris, Peter, Flegg, Clive, Graham, Katherine, Gray, Shirley, Hammersley, Kevin, Jones, Matthew, Jones, Ildiko, Kustos, Susan, Larkin, Karim, Mahawish, Sarah, Maxwell, Jane, Minton, Kavya, Mohandas, Martin, Mostert, Ed, Moran, Christopher, Murphy, Monika, Pasztor, Hassan, Paraiso, Nikhil, Premchand, Haris, Rathur, Mark, Roberts, Amy, Robinson, Andrew, Rosser, Stefan, Schumacher, Monty, Silverdale, Philip, Stanley, Neil, Todd, Alastair, Watt, Martin, Wiselka

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Structured Prompt Interrogation and Recursive Extraction of Semantics (SPIRES): a method for populating knowledge bases using zero-shot learning by Caufield, J Harry, Hegde, Harshad, Emonet, Vincent, Harris, Nomi L, Joachimiak, Marcin P, Matentzoglu, Nicolas, Kim, HyeongSik, Moxon, Sierra, Reese, Justin T, Haendel, Melissa A, Robinson, Peter N, Mungall, Christopher J

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Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, plat... by James, Nicholas D, Prof, Sydes, Matthew R, MSc, Clarke, Noel W, Prof, Mason, Malcolm D, Prof, Dearnaley, David P, Prof, Spears, Melissa R, MSc, Ritchie, Alastair W S, MD, Parker, Christopher C, MD, Russell, J Martin, FRCR, Attard, Gerhardt, MD PhD, de Bono, Johann, Prof, Cross, William, PhD, Jones, Rob J, Prof, Thalmann, George, Prof, Amos, Claire, PhD, Matheson, David, PhD, Millman, Robin, Alzouebi, Mymoona, FRCR, Beesley, Sharon, FRCR, Birtle, Alison J, MD, Brock, Susannah, FRCR, Cathomas, Richard, MD, Chakraborti, Prabir, FRCR, Chowdhury, Simon, MD, Cook, Audrey, FRCR, Elliott, Tony, PhD, Gale, Joanna, DM, Gibbs, Stephanie, FRCR, Graham, John D, FRCP, Hetherington, John, FRCS[Eng], Hughes, Robert, FRCR, Laing, Robert, FRCR, McKinna, Fiona, FRCR, McLaren, Duncan B, FRCR, FRCP[Ed], O'Sullivan, Joe M, Prof, Parikh, Omi, FRCR, Peedell, Clive, FRCR, Protheroe, Andrew, PhD, Robinson, Angus J, FRCR, Srihari, Narayanan, MD, Srinivasan, Rajaguru, FRCR, Staffurth, John, MD, Sundar, Santhanam, FRCR, Tolan, Shaun, MD, Tsang, David, MCRP, Wagstaff, John, Prof, Parmar, Mahesh K B, Prof

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Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3‑Kinase δ for the Treatment of Respiratory Disease by Down, Kenneth, Amour, Augustin, Baldwin, Ian R, Cooper, Anthony W. J, Deakin, Angela M, Felton, Leigh M, Guntrip, Stephen B, Hardy, Charlotte, Harrison, Zoë A, Jones, Katherine L, Jones, Paul, Keeling, Suzanne E, Le, Joelle, Livia, Stefano, Lucas, Fiona, Lunniss, Christopher J, Parr, Nigel J, Robinson, Ed, Rowland, Paul, Smith, Sarah, Thomas, Daniel A, Vitulli, Giovanni, Washio, Yoshiaki, Hamblin, J. Nicole

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Single prolonged stress decreases sign-tracking and cue-induced reinstatement of cocaine-seeking by Fitzpatrick, Christopher J., Jagannathan, Lakshmikripa, Lowenstein, Elijah D., Robinson, Terry E., Becker, Jill B., Morrow, Jonathan D.

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Self-expanding transcatheter aortic valve replacement using alternative access sites in symptomatic patients with severe aortic stenosis deemed extreme risk of surgery by Reardon, Michael J., MD, Adams, David H., MD, Coselli, Joseph S., MD, Deeb, G. Michael, MD, Kleiman, Neal S., MD, Chetcuti, Stan, MD, Yakubov, Steven J., MD, Heimansohn, David, MD, Hermiller, James, MD, Hughes, G. Chad, MD, Harrison, J. Kevin, MD, Khabbaz, Kamal, MD, Tadros, Peter, MD, Zorn, George L., MD, Merhi, William, MD, Heiser, John, MD, Petrossian, George, MD, Robinson, Newell, MD, Maini, Brijeshwar, MD, Mumtaz, Mubashir, MD, Lee, Joon Sup, MD, Gleason, Thomas G., MD, Resar, Jon, MD, Conte, John, MD, Watson, Daniel, MD, Chenoweth, Sharla, MS, Popma, Jeffrey J., MD

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