DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts by Roulois, David, Loo Yau, Helen, Singhania, Rajat, Wang, Yadong, Danesh, Arnavaz, Shen, Shu Yi, Han, Han, Liang, Gangning, Jones, Peter A., Pugh, Trevor J., O’Brien, Catherine, De Carvalho, Daniel D.

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Polycystic Ovary Syndrome with Hyperandrogenism Is Characterized by an Increased Risk of Hepatic Steatosis Compared to Nonhyperandrogenic PCOS Phenotypes and Healthy Controls, Inde... by Jones, Helen, Sprung, Victoria S, Pugh, Christopher J. A, Daousi, Christina, Irwin, Andrew, Aziz, Nabil, Adams, Valerie L, Thomas, E. Louise, Bell, Jimmy D, Kemp, Graham J, Cuthbertson, Daniel J

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Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy by Rehman, Sumaiyah K., Haynes, Jennifer, Collignon, Evelyne, Brown, Kevin R., Wang, Yadong, Nixon, Allison M.L., Bruce, Jeffrey P., Wintersinger, Jeffrey A., Singh Mer, Arvind, Lo, Edwyn B.L., Leung, Cherry, Lima-Fernandes, Evelyne, Pedley, Nicholas M., Soares, Fraser, McGibbon, Sophie, He, Housheng Hansen, Pollet, Aaron, Pugh, Trevor J., Haibe-Kains, Benjamin, Morris, Quaid, Ramalho-Santos, Miguel, Goyal, Sidhartha, Moffat, Jason, O’Brien, Catherine A.

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Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy by Lan, Xiaoyang, Jörg, David J, Cavalli, Florence M G, Richards, Laura M, Nguyen, Long V, Vanner, Robert J, Guilhamon, Paul, Lee, Lilian, Kushida, Michelle M, Pellacani, Davide, Park, Nicole I, Coutinho, Fiona J, Whetstone, Heather, Selvadurai, Hayden J, Che, Clare, Luu, Betty, Carles, Annaick, Moksa, Michelle, Rastegar, Naghmeh, Head, Renee, Dolma, Sonam, Prinos, Panagiotis, Cusimano, Michael D, Das, Sunit, Bernstein, Mark, Arrowsmith, Cheryl H, Mungall, Andrew J, Moore, Richard A, Ma, Yussanne, Gallo, Marco, Lupien, Mathieu, Pugh, Trevor J, Taylor, Michael D, Hirst, Martin, Eaves, Connie J, Simons, Benjamin D, Dirks, Peter B

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Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling by Loganathan, Sampath K, Schleicher, Krista, Malik, Ahmad, Quevedo, Rene, Langille, Ellen, Teng, Katie, Oh, Robin H, Rathod, Bhavisha, Tsai, Ricky, Samavarchi-Tehrani, Payman, Pugh, Trevor J, Gingras, Anne-Claude, Schramek, Daniel

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Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus-Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial by Uppaluri, Ravindra, Campbell, Katie M, Egloff, Ann Marie, Zolkind, Paul, Skidmore, Zachary L, Nussenbaum, Brian, Paniello, Randal C, Rich, Jason T, Jackson, Ryan, Pipkorn, Patrik, Michel, Loren S, Ley, Jessica, Oppelt, Peter, Dunn, Gavin P, Barnell, Erica K, Spies, Nicholas C, Lin, Tianxiang, Li, Tiantian, Mulder, David T, Hanna, Youstina, Cirlan, Iulia, Pugh, Trevor J, Mudianto, Tenny, Riley, Rachel, Zhou, Liye, Jo, Vickie Y, Stachler, Matthew D, Hanna, Glenn J, Kass, Jason, Haddad, Robert, Schoenfeld, Jonathan D, Gjini, Evisa, Lako, Ana, Thorstad, Wade, Gay, Hiram A, Daly, Mackenzie, Rodig, Scott J, Hagemann, Ian S, Kallogjeri, Dorina, Piccirillo, Jay F, Chernock, Rebecca D, Griffith, Malachi, Griffith, Obi L, Adkins, Douglas R

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Mutational heterogeneity in cancer and the search for new cancer-associated genes by Lawrence, Michael S, Stojanov, Petar, Polak, Paz, Kryukov, Gregory V, Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L, Stewart, Chip, Mermel, Craig H, Roberts, Steven A, Kiezun, Adam, Hammerman, Peter S, McKenna, Aaron, Drier, Yotam, Zou, Lihua, Ramos, Alex H, Pugh, Trevor J, Stransky, Nicolas, Helman, Elena, Kim, Jaegil, Sougnez, Carrie, Ambrogio, Lauren, Nickerson, Elizabeth, Shefler, Erica, Cortés, Maria L, Auclair, Daniel, Saksena, Gordon, Voet, Douglas, Noble, Michael, DiCara, Daniel, Lin, Pei, Lichtenstein, Lee, Heiman, David I, Fennell, Timothy, Imielinski, Marcin, Hernandez, Bryan, Hodis, Eran, Baca, Sylvan, Dulak, Austin M, Lohr, Jens, Landau, Dan-Avi, Wu, Catherine J, Melendez-Zajgla, Jorge, Hidalgo-Miranda, Alfredo, Koren, Amnon, McCarroll, Steven A, Mora, Jaume, Crompton, Brian, Onofrio, Robert, Parkin, Melissa, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B, Roberts, Charles W M, Biegel, Jaclyn A, Stegmaier, Kimberly, Bass, Adam J, Garraway, Levi A, Meyerson, Matthew, Golub, Todd R, Gordenin, Dmitry A, Sunyaev, Shamil, Lander, Eric S, Getz, Gad

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Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas by Seiwert, Tanguy Y, Zuo, Zhixiang, Keck, Michaela K, Khattri, Arun, Pedamallu, Chandra S, Stricker, Thomas, Brown, Christopher, Pugh, Trevor J, Stojanov, Petar, Cho, Juok, Lawrence, Michael S, Getz, Gad, Brägelmann, Johannes, DeBoer, Rebecca, Weichselbaum, Ralph R, Langerman, Alexander, Portugal, Louis, Blair, Elizabeth, Stenson, Kerstin, Lingen, Mark W, Cohen, Ezra E W, Vokes, Everett E, White, Kevin P, Hammerman, Peter S

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Landscape of genomic alterations in cervical carcinomas by Ojesina, Akinyemi I, Lichtenstein, Lee, Freeman, Samuel S, Pedamallu, Chandra Sekhar, Imaz-Rosshandler, Ivan, Pugh, Trevor J, Cherniack, Andrew D, Ambrogio, Lauren, Cibulskis, Kristian, Bertelsen, Bjørn, Romero-Cordoba, Sandra, Treviño, Victor, Vazquez-Santillan, Karla, Guadarrama, Alberto Salido, Wright, Alexi A, Rosenberg, Mara W, Duke, Fujiko, Kaplan, Bethany, Wang, Rui, Nickerson, Elizabeth, Walline, Heather M, Lawrence, Michael S, Stewart, Chip, Carter, Scott L, McKenna, Aaron, Rodriguez-Sanchez, Iram P, Espinosa-Castilla, Magali, Woie, Kathrine, Bjorge, Line, Wik, Elisabeth, Halle, Mari K, Hoivik, Erling A, Krakstad, Camilla, Gabiño, Nayeli Belem, Gómez-Macías, Gabriela Sofia, Valdez-Chapa, Lezmes D, Garza-Rodríguez, María Lourdes, Maytorena, German, Vazquez, Jorge, Rodea, Carlos, Cravioto, Adrian, Cortes, Maria L, Greulich, Heidi, Crum, Christopher P, Neuberg, Donna S, Hidalgo-Miranda, Alfredo, Escareno, Claudia Rangel, Akslen, Lars A, Carey, Thomas E, Vintermyr, Olav K, Gabriel, Stacey B, Barrera-Saldaña, Hugo A, Melendez-Zajgla, Jorge, Getz, Gad, Salvesen, Helga B, Meyerson, Matthew

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Recurrent and functional regulatory mutations in breast cancer by Rheinbay, Esther, Parasuraman, Prasanna, Grimsby, Jonna, Tiao, Grace, Engreitz, Jesse M, Kim, Jaegil, Lawrence, Michael S, Taylor-Weiner, Amaro, Rodriguez-Cuevas, Sergio, Rosenberg, Mara, Hess, Julian, Stewart, Chip, Maruvka, Yosef E, Stojanov, Petar, Cortes, Maria L, Seepo, Sara, Cibulskis, Carrie, Tracy, Adam, Pugh, Trevor J, Lee, Jesse, Zheng, Zongli, Ellisen, Leif W, Iafrate, A John, Boehm, Jesse S, Gabriel, Stacey B, Meyerson, Matthew, Golub, Todd R, Baselga, Jose, Hidalgo-Miranda, Alfredo, Shioda, Toshi, Bernards, Andre, Lander, Eric S, Getz, Gad

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High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis by Greenaway, R L, Santolini, V, Bennison, M J, Alston, B M, Pugh, C J, Little, M A, Miklitz, M, Eden-Rump, E G B, Clowes, R, Shakil, A, Cuthbertson, H J, Armstrong, H, Briggs, M E, Jelfs, K E, Cooper, A I

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EVOLVE: A Multicenter Open-Label Single-Arm Clinical and Translational Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer after PARP Inhibition Progression by Lheureux, Stephanie, Oaknin, Ana, Garg, Swati, Bruce, Jeffrey P, Madariaga, Ainhoa, Dhani, Neesha C, Bowering, Valerie, White, Justin, Accardi, Sarah, Tan, Qian, Braunstein, Marsela, Karakasis, Katherine, Cirlan, Iulia, Pedersen, Stephanie, Li, Tiantiam, Fariñas-Madrid, Lorena, Lee, Yeh Chen, Liu, Zhihui Amy, Pugh, Trevor J, Oza, Amit M

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Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors by Akbay, Esra A, Koyama, Shohei, Carretero, Julian, Altabef, Abigail, Tchaicha, Jeremy H, Christensen, Camilla L, Mikse, Oliver R, Cherniack, Andrew D, Beauchamp, Ellen M, Pugh, Trevor J, Wilkerson, Matthew D, Fecci, Peter E, Butaney, Mohit, Reibel, Jacob B, Soucheray, Margaret, Cohoon, Travis J, Janne, Pasi A, Meyerson, Matthew, Hayes, D Neil, Shapiro, Geoffrey I, Shimamura, Takeshi, Sholl, Lynette M, Rodig, Scott J, Freeman, Gordon J, Hammerman, Peter S, Dranoff, Glenn, Wong, Kwok-Kin

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Discovery and characterization of artifactual mutations in deep coverage targeted capture sequencing data due to oxidative DNA damage during sample preparation by Costello, Maura, Pugh, Trevor J, Fennell, Timothy J, Stewart, Chip, Lichtenstein, Lee, Meldrim, James C, Fostel, Jennifer L, Friedrich, Dennis C, Perrin, Danielle, Dionne, Danielle, Kim, Sharon, Gabriel, Stacey B, Lander, Eric S, Fisher, Sheila, Getz, Gad

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The effect of age and mitigation strategies during hot water immersion on orthostatic intolerance and thermal stress by Steward, Charles J., Menzies, Campbell, Clarke, Neil D., Harwood, Amy E., Hill, Mathew, Pugh, Christopher J. A., Thake, C. Douglas, Cullen, Tom

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Dissecting the genomic complexity underlying medulloblastoma by Jones, David T W, Jäger, Natalie, Kool, Marcel, Zichner, Thomas, Hutter, Barbara, Sultan, Marc, Cho, Yoon-Jae, Pugh, Trevor J, Hovestadt, Volker, Stütz, Adrian M, Rausch, Tobias, Warnatz, Hans-Jörg, Ryzhova, Marina, Bender, Sebastian, Sturm, Dominik, Pleier, Sabrina, Cin, Huriye, Pfaff, Elke, Sieber, Laura, Wittmann, Andrea, Remke, Marc, Witt, Hendrik, Hutter, Sonja, Tzaridis, Theophilos, Weischenfeldt, Joachim, Raeder, Benjamin, Avci, Meryem, Amstislavskiy, Vyacheslav, Zapatka, Marc, Weber, Ursula D, Wang, Qi, Lasitschka, Bärbel, Bartholomae, Cynthia C, Schmidt, Manfred, von Kalle, Christof, Ast, Volker, Lawerenz, Chris, Eils, Jürgen, Kabbe, Rolf, Benes, Vladimir, van Sluis, Peter, Koster, Jan, Volckmann, Richard, Shih, David, Betts, Matthew J, Russell, Robert B, Coco, Simona, Tonini, Gian Paolo, Schüller, Ulrich, Hans, Volkmar, Graf, Norbert, Kim, Yoo-Jin, Monoranu, Camelia, Roggendorf, Wolfgang, Unterberg, Andreas, Herold-Mende, Christel, Milde, Till, Kulozik, Andreas E, von Deimling, Andreas, Witt, Olaf, Maass, Eberhard, Rössler, Jochen, Ebinger, Martin, Schuhmann, Martin U, Frühwald, Michael C, Hasselblatt, Martin, Jabado, Nada, Rutkowski, Stefan, von Bueren, André O, Williamson, Dan, Clifford, Steven C, McCabe, Martin G, Collins, V Peter, Wolf, Stephan, Wiemann, Stefan, Lehrach, Hans, Brors, Benedikt, Scheurlen, Wolfram, Felsberg, Jörg, Reifenberger, Guido, Northcott, Paul A, Taylor, Michael D, Meyerson, Matthew, Pomeroy, Scott L, Yaspo, Marie-Laure, Korbel, Jan O, Korshunov, Andrey, Eils, Roland, Pfister, Stefan M, Lichter, Peter

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Risk assessment tools in criminal justice and forensic psychiatry: The need for better data by Douglas, T, Pugh, J, Singh, I, Savulescu, J, Fazel, S

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Feasibility and reliability of frailty assessment in the critically ill: a systematic review by Pugh, Richard J, Ellison, Amy, Pye, Kate, Subbe, Christian P, Thorpe, Chris M, Lone, Nazir I, Clegg, Andrew

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The genomic complexity of primary human prostate cancer by BERGER, Michael F, LAWRENCE, Michael S, ONOFRIO, Robert, CARTER, Scott L, PARK, Kyung, HABEGGER, Lukas, AMBROGIO, Lauren, FENNELL, Timothy, PARKIN, Melissa, SAKSENA, Gordon, VOET, Douglas, RAMOS, Alex H, DEMICHELIS, Francesca, PUGH, Trevor J, WILKINSON, Jane, FISHER, Sheila, WINCKLER, Wendy, MAHAN, Scott, ARDLIE, Kristin, BALDWIN, Jennifer, SIMONS, Jonathan W, KITABAYASHI, Naoki, MACDONALD, Theresa Y, DRIER, Yotam, KANTOFF, Philip W, CHIN, Lynda, GABRIEL, Stacey B, GERSTEIN, Mark B, GOLUB, Todd R, MEYERSON, Matthew, TEWARI, Ashutosh, LANDER, Eric S, GETZ, Gad, RUBIN, Mark A, CIBULSKIS, Kristian, GARRAWAY, Levi A, SIVACHENKO, Andrey Y, SBONER, Andrea, ESGUEVA, Raquel, PFLUEGER, Dorothee, SOUGNEZ, Carrie

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates by Kis, Olena, Kaedbey, Rayan, Chow, Signy, Danesh, Arnavaz, Dowar, Mark, Li, Tiantian, Li, Zhihua, Liu, Jessica, Mansour, Mark, Masih-Khan, Esther, Zhang, Tong, Bratman, Scott V, Oza, Amit M, Kamel-Reid, Suzanne, Trudel, Suzanne, Pugh, Trevor J

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