A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins

by Fryszkowska, Anna, An, Chihui, Alvizo, Oscar, Banerjee, Goutami, Canada, Keith A., Cao, Yang, DeMong, Duane, Devine, Paul N., Duan, Da, Elgart, David M., Farasat, Iman, Gauthier, Donald R., Guidry, Erin N., Jia, Xiujuan, Kong, Jongrock, Kruse, Nikki, Lexa, Katrina W., Makarov, Alexey A., Mann, Benjamin F., Milczek, Erika M., Mitchell, Vesna, Nazor, Jovana, Neri, Claudia, Orr, Robert K., Orth, Peter, Phillips, Eric M., Riggins, James N., Schafer, Wes A., Silverman, Steven M., Strulson, Christopher A., Subramanian, Nandhitha, Voladri, Rama, Yang, Hao, Yang, Jie, Yi, Xiang, Zhang, Xiyun, Zhong, Wendy
Published in Science (American Association for the Advancement of Science)

Investigating cone photoreceptor development using patient-derived NRL null retinal organoids

by Kallman, Alyssa, Capowski, Elizabeth E, Wang, Jie, Kaushik, Aniruddha M, Jansen, Alex D, Edwards, Kimberly L, Chen, Liben, Berlinicke, Cynthia A, Joseph Phillips, M, Pierce, Eric A, Qian, Jiang, Wang, Tza-Huei, Gamm, David M, Zack, Donald J
Published in Communications biology

Zileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammation

by Gounaris, Elias, Heiferman, Michael J, Heiferman, Jeffrey R, Shrivastav, Manisha, Vitello, Dominic, Blatner, Nichole R, Knab, Lawrence M, Phillips, Joseph D, Cheon, Eric C, Grippo, Paul J, Khazaie, Khashayarsha, Munshi, Hidayatullah G, Bentrem, David J
Published in PloS one

A mesoscale connectome of the mouse brain

by Oh, Seung Wook, Harris, Julie A, Ng, Lydia, Winslow, Brent, Cain, Nicholas, Mihalas, Stefan, Wang, Quanxin, Lau, Chris, Kuan, Leonard, Henry, Alex M, Mortrud, Marty T, Ouellette, Benjamin, Nguyen, Thuc Nghi, Sorensen, Staci A, Slaughterbeck, Clifford R, Wakeman, Wayne, Li, Yang, Feng, David, Ho, Anh, Nicholas, Eric, Hirokawa, Karla E, Bohn, Phillip, Joines, Kevin M, Peng, Hanchuan, Hawrylycz, Michael J, Phillips, John W, Hohmann, John G, Wohnoutka, Paul, Gerfen, Charles R, Koch, Christof, Bernard, Amy, Dang, Chinh, Jones, Allan R, Zeng, Hongkui
Published in Nature (London)

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

by Do, Ron, Stitziel, Nathan O, Won, Hong-Hee, Jørgensen, Anders Berg, Duga, Stefano, Angelica Merlini, Pier, Kiezun, Adam, Farrall, Martin, Goel, Anuj, Zuk, Or, Guella, Illaria, Asselta, Rosanna, Lange, Leslie A, Peloso, Gina M, Auer, Paul L, Girelli, Domenico, Martinelli, Nicola, Farlow, Deborah N, DePristo, Mark A, Roberts, Robert, Stewart, Alexander F R, Saleheen, Danish, Danesh, John, Epstein, Stephen E, Sivapalaratnam, Suthesh, Hovingh, G Kees, Kastelein, John J, Samani, Nilesh J, Schunkert, Heribert, Erdmann, Jeanette, Shah, Svati H, Kraus, William E, Davies, Robert, Nikpay, Majid, Johansen, Christopher T, Wang, Jian, Hegele, Robert A, Hechter, Eliana, Marz, Winfried, Kleber, Marcus E, Huang, Jie, Johnson, Andrew D, Li, Mingyao, Burke, Greg L, Gross, Myron, Liu, Yongmei, Assimes, Themistocles L, Heiss, Gerardo, Lange, Ethan M, Folsom, Aaron R, Taylor, Herman A, Olivieri, Oliviero, Hamsten, Anders, Clarke, Robert, Reilly, Dermot F, Yin, Wu, Rivas, Manuel A, Donnelly, Peter, Rossouw, Jacques E, Psaty, Bruce M, Herrington, David M, Wilson, James G, Rich, Stephen S, Bamshad, Michael J, Tracy, Russell P, Cupples, L Adrienne, Rader, Daniel J, Reilly, Muredach P, Spertus, John A, Cresci, Sharon, Hartiala, Jaana, Tang, W H Wilson, Hazen, Stanley L, Allayee, Hooman, Reiner, Alex P, Carlson, Christopher S, Kooperberg, Charles, Jackson, Rebecca D, Boerwinkle, Eric, Lander, Eric S, Schwartz, Stephen M, Siscovick, David S, McPherson, Ruth, Tybjaerg-Hansen, Anne, Abecasis, Goncalo R, Watkins, Hugh, Nickerson, Deborah A, Ardissino, Diego, Sunyaev, Shamil R, O'Donnell, Christopher J, Altshuler, David, Gabriel, Stacey, Kathiresan, Sekar
Published in Nature (London)

Optimal resistance exercise training parameters for stroke recovery: A protocol for a systematic review

by Noguchi, Kenneth S, Moncion, Kevin, Wiley, Elise, Morgan, Ashley, Huynh, Eric, Beauchamp, Marla K, Phillips, Stuart M, Thabane, Lehana, Tang, Ada
Published in PloS one

Immune control of HIV-1 after early treatment of acute infection

by Walker, Bruce D, Rosenberg, Eric S, Altfeld, Marcus, Poon, Samuel H, Phillips, Mary N, Wilkes, Barbara M, Eldridge, Robert L, Robbins, Gregory K, D'Aquila, Richard T, Goulder, Philip J. R
Published in Nature (London)

Integrating gene expression and clinical data to identify drug repurposing candidates for hyperlipidemia and hypertension

by Wu, Patrick, Feng, QiPing, Kerchberger, Vern Eric, Nelson, Scott D, Chen, Qingxia, Li, Bingshan, Edwards, Todd L, Cox, Nancy J, Phillips, Elizabeth J, Stein, C Michael, Roden, Dan M, Denny, Joshua C, Wei, Wei-Qi
Published in Nature communications

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

by Kathiresan, Sekar, Rader, Daniel J, Musunuru, Kiran, Strong, Alanna, Frank-Kamenetsky, Maria, Lee, Noemi E, Ahfeldt, Tim, Sachs, Katherine V, Li, Xiaoyu, Li, Hui, Kuperwasser, Nicolas, Ruda, Vera M, Pirruccello, James P, Muchmore, Brian, Prokunina-Olsson, Ludmila, Hall, Jennifer L, Schadt, Eric E, Morales, Carlos R, Lund-Katz, Sissel, Phillips, Michael C, Wong, Jamie, Cantley, William, Racie, Timothy, Ejebe, Kenechi G, Orho-Melander, Marju, Melander, Olle, Koteliansky, Victor, Fitzgerald, Kevin, Krauss, Ronald M, Cowan, Chad A
Published in Nature (London)

Cre Recombinase-Mediated Restoration of Nigrostriatal Dopamine in Dopamine-Deficient Mice Reverses Hypophagia and Bradykinesia

by Hnasko, Thomas S., Perez, Francisco A., Scouras, Alex D., Stoll, Elizabeth A., Gale, Samuel D., Luquet, Serge, Phillips, Paul E. M., Kremer, Eric J., Palmiter, Richard D.
Published in Proceedings of the National Academy of Sciences - PNAS

Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure

by Rasooly, Danielle, Peloso, Gina M, Pereira, Alexandre C, Dashti, Hesam, Giambartolomei, Claudia, Wheeler, Eleanor, Aung, Nay, Ferolito, Brian R, Pietzner, Maik, Farber-Eger, Eric H, Wells, Quinn Stanton, Kosik, Nicole M, Gaziano, Liam, Posner, Daniel C, Bento, A Patrícia, Hui, Qin, Liu, Chang, Aragam, Krishna, Wang, Zeyuan, Charest, Brian, Huffman, Jennifer E, Wilson, Peter W F, Phillips, Lawrence S, Whittaker, John, Munroe, Patricia B, Petersen, Steffen E, Cho, Kelly, Leach, Andrew R, Magariños, María Paula, Gaziano, John Michael, Langenberg, Claudia, Sun, Yan V, Joseph, Jacob, Casas, Juan P
Published in Nature communications

A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle

by Goode, Benjamin, Mondal, Gourish, Hyun, Michael, Ruiz, Diego Garrido, Lin, Yu-Hsiu, Van Ziffle, Jessica, Joseph, Nancy M, Onodera, Courtney, Talevich, Eric, Grenert, James P, Hewedi, Iman H, Snuderl, Matija, Brat, Daniel J, Kleinschmidt-DeMasters, Bette K, Rodriguez, Fausto J, Louis, David N, Yong, William H, Lopes, M Beatriz, Rosenblum, Marc K, Butowski, Nicholas, Tihan, Tarik, Bollen, Andrew W, Phillips, Joanna J, Wiita, Arun P, Yeh, Iwei, Jacobson, Matthew P, Bastian, Boris C, Perry, Arie, Solomon, David A
Published in Nature communications

Molecular determinants of mouse neurovirulence and mosquito infection for Western equine encephalitis virus

by Mossel, Eric C, Ledermann, Jeremy P, Phillips, Aaron T, Borland, Erin M, Powers, Ann M, Olson, Ken E
Published in PloS one

Global distribution of earthworm diversity

by Phillips, Helen R P, Guerra, Carlos A, Bartz, Marie L C, Brown, George, Crowther, Thomas W, Ferlian, Olga, Gongalsky, Konstantin B, van den Hoogen, Johan, Orgiazzi, Alberto, Routh, Devin, Bach, Elizabeth M, Bennett, Joanne, Loreau, Michel, Mathieu, Jérôme, Mulder, Christian, Ramirez, Kelly S, Rillig, Matthias C, Thakur, Madhav P, Wall, Diana H, Ayuke, Fredrick O, Bedano, José C, Birkhofer, Klaus, Blanchart, Eric, Blossey, Bernd, Bolger, Thomas, Bradley, Robert L, Callaham, Mac A, Capowiez, Yvan, Caulfield, Mark E, Dávalos, Andrea, Duhour, Andrés Esteban, van Eekeren, Nick, Emmerling, Christoph, Falco, Liliana B, Fernández, Rosa, Fonte, Steven J, Fragoso, Carlos, Franco, André L C, Gholami, Shaieste, Gundale, Michael J, Hackenberger, Davorka K, Hernández, Luis M, Hishi, Takuo, Holmstrup, Martin, Hopfensperger, Kristine N, Lwanga, Esperanza Huerta, Huhta, Veikko, Iannone, 3rd, Basil V, Iordache, Madalina, Kaneko, Nobuhiro, Keith, Aidan M, Kelly, Courtland A, Kernecker, Maria L, Klaminder, Jonatan, Kukkonen, Sanna T, Lalthanzara, H, Lammel, Daniel R, Lebedev, Iurii M, Lidon, Juan B Jesus, Lincoln, Noa K, Loss, Scott R, Marichal, Raphael, Matula, Radim, Moos, Jan Hendrik, Moreno, Gerardo, Morón-Ríos, Alejandro, Neirynck, Johan, Nuutinen, Visa, Rahman P, Mujeeb, Pansu, Johan, Paudel, Shishir, Pérès, Guénola, Piñeiro, Raúl, Ponge, Jean-François, Rebollo, Salvador, Rodeiro-Iglesias, Javier, Rodríguez, Miguel Á, Rousseau, Guillaume X, Rozen, Anna, van Schaik, Loes, Scharenbroch, Bryant C, Schmidt, Olaf, Schröder, Boris, Shashkov, Maxim P, Singh, Jaswinder, Smith, Sandy M, Steinwandter, Michael, Trigo, Dolores, Tsukamoto, Jiro, de Valença, Anne W, Vanek, Steven J, Virto, Iñigo, Wackett, Adrian A, Wehr, Nathaniel H, Whalen, Joann K, Wironen, Michael B, Wolters, Volkmar, Zenkova, Irina V, Zhang, Weixin, Eisenhauer, Nico
Published in Science (American Association for the Advancement of Science)

Targeted selected reaction monitoring mass spectrometric immunoassay for insulin-like growth factor 1

by Niederkofler, Eric E, Phillips, David A, Krastins, Bryan, Kulasingam, Vathany, Kiernan, Urban A, Tubbs, Kemmons A, Peterman, Scott M, Prakash, Amol, Diamandis, Eleftherios P, Lopez, Mary F, Nedelkov, Dobrin
Published in PloS one

Transcriptional landscape of the prenatal human brain

by Miller, Jeremy A, Ding, Song-Lin, Sunkin, Susan M, Smith, Kimberly A, Ng, Lydia, Szafer, Aaron, Ebbert, Amanda, Riley, Zackery L, Royall, Joshua J, Aiona, Kaylynn, Arnold, James M, Bennet, Crissa, Bertagnolli, Darren, Brouner, Krissy, Butler, Stephanie, Caldejon, Shiella, Carey, Anita, Cuhaciyan, Christine, Dalley, Rachel A, Dee, Nick, Dolbeare, Tim A, Facer, Benjamin A C, Feng, David, Fliss, Tim P, Gee, Garrett, Goldy, Jeff, Gourley, Lindsey, Gregor, Benjamin W, Gu, Guangyu, Howard, Robert E, Jochim, Jayson M, Kuan, Chihchau L, Lau, Christopher, Lee, Chang-Kyu, Lee, Felix, Lemon, Tracy A, Lesnar, Phil, McMurray, Bergen, Mastan, Naveed, Mosqueda, Nerick, Naluai-Cecchini, Theresa, Ngo, Nhan-Kiet, Nyhus, Julie, Oldre, Aaron, Olson, Eric, Parente, Jody, Parker, Patrick D, Parry, Sheana E, Stevens, Allison, Pletikos, Mihovil, Reding, Melissa, Roll, Kate, Sandman, David, Sarreal, Melaine, Shapouri, Sheila, Shapovalova, Nadiya V, Shen, Elaine H, Sjoquist, Nathan, Slaughterbeck, Clifford R, Smith, Michael, Sodt, Andy J, Williams, Derric, Zöllei, Lilla, Fischl, Bruce, Gerstein, Mark B, Geschwind, Daniel H, Glass, Ian A, Hawrylycz, Michael J, Hevner, Robert F, Huang, Hao, Jones, Allan R, Knowles, James A, Levitt, Pat, Phillips, John W, Sestan, Nenad, Wohnoutka, Paul, Dang, Chinh, Bernard, Amy, Hohmann, John G, Lein, Ed S
Published in Nature (London)

Delivery of Small Interfering RNA by Peptide-Targeted Mesoporous Silica Nanoparticle-Supported Lipid Bilayers

by Ashley, Carlee E, Carnes, Eric C, Epler, Katharine E, Padilla, David P, Phillips, Genevieve K, Castillo, Robert E, Wilkinson, Dan C, Wilkinson, Brian S, Burgard, Cameron A, Kalinich, Robin M, Townson, Jason L, Chackerian, Bryce, Willman, Cheryl L, Peabody, David S, Wharton, Walker, Brinker, C. Jeffrey
Published in ACS nano

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

by Bick, Alexander G, Nandakumar, Satish K, Fulco, Charles P, Zekavat, Seyedeh M, Szeto, Mindy D, Leventhal, Matthew J, Nasser, Joseph, Chang, Kyle, Gibson, Christopher J, Lin, Amy E, Taub, Margaret A, Barnes, Kathleen C, Moscati, Arden, Psaty, Bruce M, Silverman, Edwin K, Weiss, Scott T, Palmer, Nicholette D, Vasan, Ramachandran S, Burchard, Esteban G, He, Jiang, Kaplan, Robert C, Smith, Nicholas L, Arnett, Donna K, Schwartz, David A, Correa, Adolfo, Guo, Xiuqing, Custer, Brian, Peralta, Juan M, Gui, Hongsheng, Meyers, Deborah A, McGarvey, Stephen T, Chen, Ida Yii-Der, Shoemaker, M Benjamin, Peyser, Patricia A, Broome, Jai G, Gogarten, Stephanie M, Wang, Fei Fei, Wong, Quenna, Kenny, Eimear E, North, Kari E, Launer, Lenore J, Bis, Joshua C, Lasky-Su, Jessica, Bowden, Donald W, Cupples, L Adrienne, Becker, Lewis C, Smith, Jennifer A, Kelly, Tanika N, Aslibekyan, Stella, Heckbert, Susan R, Tiwari, Hemant K, Yang, Ivana V, Heit, John A, Johnsen, Jill M, Curran, Joanne E, Wenzel, Sally E, Weeks, Daniel E, Darbar, Dawood, Moon, Jee-Young, Tracy, Russell P, Buth, Erin J, Rafaels, Nicholas, Loos, Ruth J F, Durda, Peter, Liu, Yongmei, Hou, Lifang, Kachroo, Priyadarshini, Freedman, Barry I, Levy, Daniel, Bielak, Lawrence F, Whitsel, Eric A, Ellinor, Patrick T, Fingerlin, Tasha E, Raffield, Laura M, Armasu, Sebastian M, Wheeler, Marsha M, Blangero, John, Levy, Bruce D, Sheu, Wayne Huey-Herng, Roden, Dan M, Boerwinkle, Eric, Manson, JoAnn E, Taylor, Kent D, Johnson, Andrew D, Auer, Paul L, Kooperberg, Charles, Laurie, Cathy C, Smith, Albert V, Zhao, Hongyu, Lange, Ethan, Rotter, Jerome I, Wilson, James G, Kitzman, Jacob O, Lander, Eric S, Engreitz, Jesse M, Ebert, Benjamin L, Reiner, Alexander P, Abecasis, Gonçalo, Sankaran, Vijay G, Kathiresan, Sekar
Published in Nature (London)

LucY: A Versatile New Fluorescent Reporter Protein

by Auldridge, Michele E, Cao, Hongnan, Sen, Saurabh, Franz, Laura P, Bingman, Craig A, Yennamalli, Ragothaman M, Phillips, Jr, George N, Mead, David, Steinmetz, Eric J
Published in PloS one

Integrative functional genomic analysis of human brain development and neuropsychiatric risks

by Li, Mingfeng, Santpere, Gabriel, Imamura Kawasawa, Yuka, Evgrafov, Oleg V, Gulden, Forrest O, Pochareddy, Sirisha, Sunkin, Susan M, Li, Zhen, Shin, Yurae, Zhu, Ying, Sousa, André M M, Werling, Donna M, Kitchen, Robert R, Kang, Hyo Jung, Pletikos, Mihovil, Choi, Jinmyung, Muchnik, Sydney, Xu, Xuming, Wang, Daifeng, Lorente-Galdos, Belen, Liu, Shuang, Giusti-Rodríguez, Paola, Won, Hyejung, de Leeuw, Christiaan A, Pardiñas, Antonio F, Hu, Ming, Jin, Fulai, Li, Yun, Owen, Michael J, O'Donovan, Michael C, Walters, James T R, Posthuma, Danielle, Reimers, Mark A, Levitt, Pat, Weinberger, Daniel R, Hyde, Thomas M, Kleinman, Joel E, Geschwind, Daniel H, Hawrylycz, Michael J, State, Matthew W, Sanders, Stephan J, Sullivan, Patrick F, Gerstein, Mark B, Lein, Ed S, Knowles, James A, Sestan, Nenad
Published in Science (American Association for the Advancement of Science)