Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

by Hruban, Ralph H., Moffitt, Richard A., Gupta, Manaswi, Getz, Gad, Gabriel, Stacey B., Meyerson, Matthew, Laird, Peter W., Loher, Phillipe, Rigoutsos, Isidore, Telonis, Aristeidis G., Mezlini, Aziz M., Hoadley, Katherine A., Murray, Bradley A., Hess, Julian, Zhang, Hailei, Tiao, Grace, Schumacher, Steven E., Noble, Michael S., Gehlenborg, Nils, Lawrence, Michael S., Bowlby, Reanne, Birol, Inanc, Weinstein, John N., Spellman, Paul T., Liu, Yuexin, Paul, Drwiega, Smyrk, Thomas, Gerken, Mark, Lau, Kevin, Renkel, Jeremy, Wise, Lisa, Yena, Peggy, Zmuda, Erik, Shih, Juliann, Balasundaram, Miruna, Chu, Andy, Chuah, Eric, Dhalla, Noreen, Mungall, Andrew J., Thiessen, Nina, Brooks, Denise, Balu, Saianand, Jefferys, Stuart R., Jones, Corbin D., Mose, Lisle E., Shi, Yan, Simons, Janae V., Soloway, Matthew G., Tan, Donghui, Chaffee, Kari, Oberg, Ann, Wheeler, David A., Bartlett, John, Stephen, Yeager, Howard, Zaren, Breggia, Anne, Shroff, Rachna T., Liu, Jia, Lolla, Laxmi, Pihl, Todd, Roggin, Kevin, Becker, Karl-Friedrich, Boice, Lori, Pretti da Cunha Tirapelli, Daniela, Huelsenbeck-Dill, Lori, Jenkins, Roger, Kemp, Rafael, Lyadov, Vladimir, Maithel, Shishir, Manikhas, Georgy, Montgomery, Eric, Noushmehr, Houtan, Owonikoko, Taofeek, Rieger-Christ, Kimberly, Sica, Gabriel, Su, Tao, Sullivan, Travis, Tarvin, Katherine, Urbanski, Stefan, Curley, Erin, Gardner, Johanna, Shelton, Candace, Bathe, Oliver, Hibshoosh, Hanina, Radenbaugh, Amie, Berrios, Mario, Bootwalla, Moiz S., Maglinte, Dennis T., Triche, Timothy J., Weisenberger, Daniel J., Kucherlapati, Melanie, Meier, Sam, Tempero, Margaret, Bailey, Peter, Gill, Anthony, Kench, James, Demchok, John A., Ferguson, Martin L., Tarnuzzer, Roy, Wang, Zhining
Published in Cancer cell

A global reference for human genetic variation

by Auton, Adam, Brooks, Lisa D, Durbin, Richard M, Garrison, Erik P, Kang, Hyun Min, Korbel, Jan O, Marchini, Jonathan L, McCarthy, Shane, McVean, Gil A, Abecasis, Gonçalo R
Published in Nature (London)

Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV): Designing Master Protocols for Evaluation of Candidate COVID-19 Therapeutics

by LaVange, Lisa, Adam, Stacey J, Currier, Judith S, Higgs, Elizabeth S, Reineck, Lora A, Hughes, Eric A, Read, Sarah W, ACTIV Therapeutics-Clinical Working Group
Published in Annals of Internal Medicine

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants

by Fu, Wenqing, O'Connor, Timothy D, Jun, Goo, Kang, Hyun Min, Abecasis, Goncalo, Leal, Suzanne M, Gabriel, Stacey, Rieder, Mark J, Altshuler, David, Shendure, Jay, Nickerson, Deborah A, Bamshad, Michael J, Akey, Joshua M
Published in Nature (London)

Parental origin of sequence variants associated with complex diseases

by Gudjonsson, Sigurjon A, Sigurdsson, Helgi, Kristinsson, Kari Th, Sigurdsson, Asgeir, Hreidarsson, Astradur B, Masson, Gisli, Ferguson-Smith, Anne C, Frigge, Michael L, Jonsson, Thorvaldur, Stacey, Simon N, Olafsson, Jon H, Benediktsdottir, Kristrun R, Gudbjartsson, Daniel F, Besenbacher, Soren, Gylfason, Arnaldur, Sigurgeirsson, Bardur, Olason, Pall I, Sverrisson, Sverrir, Stefansson, Kari, Johannsson, Oskar Th, Thorsteinsdottir, Unnur, Benediktsson, Rafn, Thorleifsson, Gudmar, Kong, Augustine, Steinthorsdottir, Valgerdur, Sulem, Patrick, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Sigurdsson, Gunnar
Published in Nature (London)

Exuberant fibroblast activity compromises lung function via ADAMTS4

by Boyd, David F, Allen, E Kaitlynn, Randolph, Adrienne G, Guo, Xi-Zhi J, Weng, Yunceng, Sanders, Catherine J, Bajracharya, Resha, Lee, Natalie K, Guy, Clifford S, Vogel, Peter, Guan, Wenda, Li, Yimin, Liu, Xiaoqing, Novak, Tanya, Newhams, Margaret M, Fabrizio, Thomas P, Wohlgemuth, Nicholas, Mourani, Peter M, Wight, Thomas N, Schultz-Cherry, Stacey, Cormier, Stephania A, Shaw-Saliba, Kathryn, Pekosz, Andrew, Rothman, Richard E, Chen, Kuan-Fu, Yang, Zifeng, Webby, Richard J, Zhong, Nanshan, Crawford, Jeremy Chase, Thomas, Paul G
Published in Nature (London)

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

by Do, Ron, Stitziel, Nathan O, Won, Hong-Hee, Jørgensen, Anders Berg, Duga, Stefano, Angelica Merlini, Pier, Kiezun, Adam, Farrall, Martin, Goel, Anuj, Zuk, Or, Guella, Illaria, Asselta, Rosanna, Lange, Leslie A, Peloso, Gina M, Auer, Paul L, Girelli, Domenico, Martinelli, Nicola, Farlow, Deborah N, DePristo, Mark A, Roberts, Robert, Stewart, Alexander F R, Saleheen, Danish, Danesh, John, Epstein, Stephen E, Sivapalaratnam, Suthesh, Hovingh, G Kees, Kastelein, John J, Samani, Nilesh J, Schunkert, Heribert, Erdmann, Jeanette, Shah, Svati H, Kraus, William E, Davies, Robert, Nikpay, Majid, Johansen, Christopher T, Wang, Jian, Hegele, Robert A, Hechter, Eliana, Marz, Winfried, Kleber, Marcus E, Huang, Jie, Johnson, Andrew D, Li, Mingyao, Burke, Greg L, Gross, Myron, Liu, Yongmei, Assimes, Themistocles L, Heiss, Gerardo, Lange, Ethan M, Folsom, Aaron R, Taylor, Herman A, Olivieri, Oliviero, Hamsten, Anders, Clarke, Robert, Reilly, Dermot F, Yin, Wu, Rivas, Manuel A, Donnelly, Peter, Rossouw, Jacques E, Psaty, Bruce M, Herrington, David M, Wilson, James G, Rich, Stephen S, Bamshad, Michael J, Tracy, Russell P, Cupples, L Adrienne, Rader, Daniel J, Reilly, Muredach P, Spertus, John A, Cresci, Sharon, Hartiala, Jaana, Tang, W H Wilson, Hazen, Stanley L, Allayee, Hooman, Reiner, Alex P, Carlson, Christopher S, Kooperberg, Charles, Jackson, Rebecca D, Boerwinkle, Eric, Lander, Eric S, Schwartz, Stephen M, Siscovick, David S, McPherson, Ruth, Tybjaerg-Hansen, Anne, Abecasis, Goncalo R, Watkins, Hugh, Nickerson, Deborah A, Ardissino, Diego, Sunyaev, Shamil R, O'Donnell, Christopher J, Altshuler, David, Gabriel, Stacey, Kathiresan, Sekar
Published in Nature (London)

A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses

by Amarilla, Alberto A., Sng, Julian D. J., Parry, Rhys, Deerain, Joshua M., Potter, James R., Setoh, Yin Xiang, Rawle, Daniel J., Le, Thuy T., Modhiran, Naphak, Wang, Xiaohui, Peng, Nias Y. G., Torres, Francisco J., Pyke, Alyssa, Harrison, Jessica J., Freney, Morgan E., Liang, Benjamin, McMillan, Christopher L. D., Cheung, Stacey T. M., Guevara, Darwin J. Da Costa, Hardy, Joshua M., Bettington, Mark, Muller, David A., Coulibaly, Fasséli, Moore, Frederick, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Hobson-Peters, Jody, Suhrbier, Andreas, Watterson, Daniel, Khromykh, Alexander A.
Published in Nature communications

High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection

by Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Hancock, Steven J, Peters, Kate M, Alvarez-Fraga, Laura, Forde, Brian M, Andersen, Stacey B, Miliya, Thyl, Harris, Patrick N A, Beatson, Scott A, Schlebusch, Sanmarie, Bergh, Haakon, Turner, Paul, Brauner, Annelie, Westerlund-Wikström, Benita, Irwin, Adam D, Schembri, Mark A
Published in eLife

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

by Ferreira, Teresa, He, Chunyan, Esko, Tõnu, Thorleifsson, Gudmar, Albrecht, Eva, Corre, Tanguy, Franceschini, Nora, Ganna, Andrea, Porcu, Eleonora, Stolk, Lisette, Tšernikova, Natalia, Tikkanen, Emmi, Wagner, Erin K, Hottenga, Jouke-Jan, Mangino, Massimo, Pers, Tune H, Atsma, Femke, Beckmann, Matthias W, Benitez, Javier, Blomqvist, Carl, Bojesen, Stig E, Bolla, Manjeet K, Brauch, Hiltrud, Brenner, Hermann, Buring, Julie E, Chanock, Stephen, Chen, Jinhui, Chenevix-Trench, Georgia, Couch, Fergus J, Czene, Kamila, D'adamo, Adamo Pio, Smith, George Davey, De Vivo, Immaculata, Demerath, Ellen W, Dennis, Joe, Dunning, Alison M, Eriksson, Johan G, Ferrucci, Luigi, Flesch-Janys, Dieter, Flyger, Henrik, Garcia, Melissa E, García-Closas, Montserrat, Gudnason, Vilmundur, Guénel, Pascal, Hall, Per, Hamann, Ute, Haring, Robin, Hartman, Catharina A, Heath, Andrew C, Hofman, Albert, Hu, Frank B, Karasik, David, Kosma, Veli-Matti, Kutalik, Zoltan, Lai, Sandra, Lindblom, Annika, Mägi, Reedik, Melbye, Mads, Michailidou, Kyriaki, Nevanlinna, Heli, Neven, Patrick, Nohr, Ellen A, Oostra, Ben A, Palotie, Aarno, Peterlongo, Paolo, Peto, Julian, Postma, Dirkje S, Pylkäs, Katri, Radice, Paolo, Ring, Susan, Rivadeneira, Fernando, Rose, Lynda M, Rudolph, Anja, Sanna, Serena, Southey, Mellissa C, Visser, Jenny A, Waldenberger, Melanie, Wallaschofski, Henri, Wolffenbuttel, Bruce Hr, Wright, Margaret J, Econs, Michael J, Khaw, Kay-Tee, Montgomery, Grant W, Streeten, Elizabeth A, Thorsteinsdottir, Unnur, Bergmann, Sven, Crisponi, Laura, Gasparini, Paolo, Gieger, Christian, Harris, Tamara B, Ingelsson, Erik, Järvelin, Marjo-Riitta, Kraft, Peter, Lawlor, Debbie, Metspalu, Andres, Pennell, Craig E, Zygmunt, Marek, Murray, Anna, Stefansson, Kari, Ong, Ken K
Published in Nature (London)

Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial

by Shepstone, Lee, Lenaghan, Elizabeth, Cooper, Cyrus, Clarke, Shane, Fong-Soe-Khioe, Rebekah, Fordham, Richard, Gittoes, Neil, Harvey, Ian, Harvey, Nick, Heawood, Alison, Holland, Richard, Howe, Amanda, Kanis, John, Marshall, Tarnya, O'Neill, Terence, Peters, Tim, Redmond, Niamh, Torgerson, David, Turner, David, McCloskey, Eugene, Shepstone, Lee, Lenaghan, Elizabeth, Cooper, Cyrus, Clarke, Shane, Fong-Soe-Khioe, Rebekah, Fordham, Ric, Gittoes, Neil, Harvey, Ian, Harvey, Nick, Heawood, Alison, Holland, Richard, Howe, Amanda, Kanis, John, Marshall, Tarnya, O'Neill, Terence, Peters, Tim, Redmond, Niamh, Torgerson, David, Turner, David, McCloskey, Eugene, Crabtree, Nicola, Duffy, Helen, Parle, Jim, Rashid, Farzana, Stant, Katie, Taylor, Kate, Thomas, Clare, Knox, Emma, Tenneson, Cherry, Williams, Helen, Adams, David, Bion, Veronica, Blacklock, Jeanette, Dyer, Tony, Bratherton, Selina, Fidler, Matt, Knight, Katharine, McGurk, Carol, Smith, Katie, Young, Stacey, Collins, Karen, Cushnaghan, Janet, Arundel, Catherine, Bell, Kerry, Clark, Laura, Collins, Sue, Gardner, Sarah, Mitchell, Natasha
Published in The Lancet (British edition)

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

by Võsa, Urmo, Stathopoulou, Maria G., de Vries, Paul S., Tanaka, Toshiko, Wu, Ying, Karlsson, Robert, Pool, René, Kemp, John P., Verweij, Niek, Smith, Albert V., Huq, Mahmudul, Deelen, Joris, Alizadeh, Behrooz Z., van der Harst, Pim, Navis, Gerjan, Snieder, Harold, Chasman, Daniel I., Meigs, James, Ligthart, Symen, Bis, Josh, Gross, Myron, Koenig, Wolfgang, Uher, Rudolf, Ward-Caviness, Cavin, Boerwinkle, Eric, Stacey, David, Eriksson, Johan, Lahti, Jari, Schraut, Katharina E., Suktitipat, Bhoom, Nutile, Teresa, Schork, Nicholas, Thiering, Elisabeth, Mahajan, Anubha, Aslibekyan, Stella, Yengo, Loïc, Rajan, Kumar B., Timpson, Nicholas, Huang, Hongyan, Uh, Hae-Won, Yanek, Lisa R., Verbanck, Marie, Magnusson, Patrik K.E., Ballantyne, Christie M., Montgomery, Grant W., Rueedi, Rico, Steri, Maristella, Stott, David J., Felix, Stephan B., Kraft, Peter, Seppälä, Ilkka, Williams, Stephen R., Moed, Matthijs, Langenberg, Claudia, Räikkönen, Katri, Sale, Michele M., Chen, Yii-Der I., James, Alan L., Soranzo, Nicole, Berenson, Gerald S., Liewald, David, Beilby, John, Ryan, Kathleen A., Balkau, Beverly, Paternoster, Lavinia, Kähönen, Mika, Sattar, Naveed, van Heemst, Diana, Gambaro, Giovanni, Ferrucci, Luigi, Karlsson, Magnus, Lind, Lars, Mori, Trevor A., Buckley, Brendan M., de Craen, Anton J.M., Scott, Rodney J., Strachan, David P., Jarvelin, Marjo-Riitta, Jukema, J. Wouter, Hamsten, Anders, Gudnason, Vilmundur, Qi, Lu, März, Winfried, Penninx, Brenda W.J.H., Worrall, Bradford B., Gibson, Greg, Oldehinkel, Albertine J., Murray, Sarah S., Pramstaller, Peter P., Deary, Ian J., Desch, Karl C., Hayward, Caroline, Arnett, Donna K., Jess, Tine, Psaty, Bruce M., Tracy, Russell P., Nolte, Ilja M., Visvikis-Siest, Sophie, Franke, Lude, Franco, Oscar H.
Published in American journal of human genetics

A structural variation reference for medical and population genetics

by Collins, Ryan L, Brand, Harrison, Karczewski, Konrad J, Zhao, Xuefang, Alföldi, Jessica, Francioli, Laurent C, Khera, Amit V, Lowther, Chelsea, Gauthier, Laura D, Wang, Harold, Watts, Nicholas A, Solomonson, Matthew, O'Donnell-Luria, Anne, Baumann, Alexander, Munshi, Ruchi, Walker, Mark, Whelan, Christopher W, Huang, Yongqing, Brookings, Ted, Sharpe, Ted, Stone, Matthew R, Valkanas, Elise, Fu, Jack, Tiao, Grace, Laricchia, Kristen M, Ruano-Rubio, Valentin, Stevens, Christine, Gupta, Namrata, Cusick, Caroline, Margolin, Lauren, Taylor, Kent D, Lin, Henry J, Rich, Stephen S, Post, Wendy S, Chen, Yii-Der Ida, Rotter, Jerome I, Nusbaum, Chad, Philippakis, Anthony, Lander, Eric, Gabriel, Stacey, Neale, Benjamin M, Kathiresan, Sekar, Daly, Mark J, Banks, Eric, MacArthur, Daniel G, Talkowski, Michael E
Published in Nature (London)

Association of BRCA2 K3326 With Small Cell Lung Cancer and Squamous Cell Cancer of the Skin

by Rafnar, Thorunn, Sigurjonsdottir, Gudbjorg R, Stacey, Simon N, Halldorsson, Gisli, Sulem, Patrick, Pardo, Luba M, Helgason, Hannes, Sigurdsson, Stefan T, Gudjonsson, Thorkell, Tryggvadottir, Laufey, Olafsdottir, Gudridur H, Jonasson, Jon G, Alexiusdottir, Kristin, Sigurdsson, Asgeir, Gudmundsson, Julius, Saemundsdottir, Jona, Sigurdsson, Jon K, Johannsdottir, Hrefna, Uitterlinden, Andre, Vermeulen, Sita H, Galesloot, Tessel E, Allain, Dawn C, Lacko, Martin, Sigurgeirsson, Bardur, Thorisdottir, Kristin, Johannsson, Oskar T, Sigurdsson, Fridbjorn, Ragnarsson, Gunnar B, Isaksson, Helgi, Hardardottir, Hronn, Gudbjartsson, Tomas, Gudbjartsson, Daniel F, Masson, Gisli, Kiemeney, Lambertus A M L, Ewart Toland, Amanda, Nijsten, Tamar, Peters, Wilbert H M, Olafsson, Jon H, Jonsson, Steinn, Thorsteinsdottir, Unnur, Thorleifsson, Gudmar, Stefansson, Kari
Published in JNCI : Journal of the National Cancer Institute

A Spring in the Desert: Infertility and Merciful Accompaniment

by Henkel, Kimberly, Koshute, Ann M., Huneck, Stacey
Published in The Linacre quarterly

Reactions to Changes in Work Control: Implications for Self-Determined and Non-Self-Determined Individuals

by Parker, Stacey L, Jimmieson, Nerina L, Amiot, Catherine E
Published in Journal of occupational health psychology

Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units: A Randomized Clinical Trial

by Blackwood, Bronagh, Tume, Lyvonne N, Morris, Kevin P, Clarke, Mike, McDowell, Clíona, Hemming, Karla, Peters, Mark J, McIlmurray, Lisa, Jordan, Joanne, Agus, Ashley, Murray, Margaret, Parslow, Roger, Walsh, Timothy S, Macrae, Duncan, Easter, Christina, Feltbower, Richard G, McAuley, Daniel F
Published in JAMA : the journal of the American Medical Association

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

by Teumer, Alexander, Li, Man, Garnaas, Maija, Taliun, Daniel, Yang, Qiong, Ko, Yi-An, Isaacs, Aaron, d'Adamo, Pio, Dieffenbach, Aida Karina, Zonderman, Alan B, Nolte, Ilja M, Smith, Albert V, Uitterlinden, Andre G, Johansson, Åsa, Kollerits, Barbara, Freedman, Barry I, Ponte, Belen, Hayward, Caroline, Helmer, Catherine, van Duijn, Cornelia M, Ruggiero, Daniela, Toniolo, Daniela, Czamara, Darina, Siscovick, David S, Gieger, Christian, Rochtchina, Elena, Holliday, Elizabeth G, Salvi, Erika, Bottinger, Erwin P, Murgia, Federico, Rivadeneira, Fernando, Ernst, Florian, Kronenberg, Florian, Homuth, Georg, Coassin, Stefan, Thun, Gian-Andri, Malerba, Giovanni, Montgomery, Grant W, Eiriksdottir, Gudny, Jacobs, Gunnar, Li, Guo, Schmidt, Helena, Lin, Honghuang, Ford, Ian, Prokopenko, Inga, Kolcic, Ivana, Stafford, Jeanette M, Gaspoz, Jean-Michel, Smith, Jennifer A, Hirschhorn, Joel N, Whitfield, John B, Coresh, Josef, Keene, Keith L, Yengo, Loic, Ferrucci, Luigi, Rose, Lynda M, Struchalin, Maksim, Kleber, Marcus E, Cavalieri, Margherita, Haun, Margot, Ciullo, Marina, Woodward, Mark, Cocca, Massimiliano, Nauck, Matthias, Waldenberger, Melanie, Pruijm, Menno, Stumvoll, Michael, Kähönen, Mika, Bouatia-Naji, Nabila, Martin, Nicholas G, Hastie, Nick, Probst-Hensch, Nicole, Devuyst, Olivier, Raitakari, Olli, Gasparini, Paolo, Kovacs, Peter, Wild, Philipp S, Froguel, Philippe, Biffar, Reiner, Schmidt, Reinhold, Scott, Rodney J, Katz, Ronit, Hwang, Shih-Jen, Enroth, Stefan, Turner, Stephen T, Zeller, Tanja, Nikopensius, Tiit, Esko, Tonu, Aalto, Ville, Igl, Wilmar, Lieb, Wolfgang, Liu, Yongmei, Snieder, Harold, Susztak, Katalin, Hamet, Pavel, Goessling, Wolfram, Chasman, Daniel I, Köttgen, Anna, Kao, W H Linda, Fox, Caroline S
Published in Nature communications

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli

by Schaale, K, Peters, K M, Murthy, A M, Fritzsche, A K, Phan, M-D, Totsika, M, Robertson, A A B, Nichols, K B, Cooper, M A, Stacey, K J, Ulett, G C, Schroder, K, Schembri, M A, Sweet, M J
Published in Mucosal immunology

Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of chronic levetiracetam treatment in 5XFAD mice: A MODEL‐AD preclinical testing core study

by Onos, Kristen D., Quinney, Sara K., Jones, David R., Masters, Andrea R., Pandey, Ravi, Keezer, Kelly J., Biesdorf, Carla, Metzger, Ingrid F., Meyers, Jill A., Peters, Johnathon, Persohn, Scott C., McCarthy, Brian P., Bedwell, Amanda A., Figueiredo, Lucas L., Cope, Zackary A., Sasner, Michael, Howell, Gareth R., Williams, Harriet M., Oblak, Adrian L., Lamb, Bruce T., Carter, Gregory W., Rizzo, Stacey J. Sukoff, Territo, Paul R.
Published in Alzheimer's & dementia : translational research & clinical interventions