The transcription factor ERG regulates a low shear stress-induced anti-thrombotic pathway in the microvasculature by Peghaire, C, Dufton, N P, Lang, M, Salles-Crawley, I I, Ahnström, J, Kalna, V, Raimondi, C, Pericleous, C, Inuabasi, L, Kiseleva, R, Muzykantov, V R, Mason, J C, Birdsey, G M, Randi, A M

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Domain I: the hidden face of antiphospholipid syndrome by Pericleous, C, Rahman, A

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Domain I of β2GPI is capable of blocking serum IgA antiphospholipid antibodies binding in vitro: an effect enhanced by PEGylation by Albay, A, Artim-Esen, B, Pericleous, C, Wincup, C, Giles, I, Rahman, A, McDonnell, T

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In vivo inhibition of antiphospholipid antibody‐induced pathogenicity utilizing the antigenic target peptide domain I of β2‐glycoprotein I: proof of concept by IOANNOU, Y., ROMAY‐PENABAD, Z., PERICLEOUS, C., GILES, I., PAPALARDO, E., VARGAS, G., SHILAGARD, T., LATCHMAN, D. S., ISENBERG, D. A., RAHMAN, A., PIERANGELI, S.

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Are endothelial microparticles potential markers of vascular dysfunction in the antiphospholipid syndrome? by Pericleous, C, Giles, I, Rahman, A

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Meta-analysis of 17 clinical trials using omega-3 fatty acids in patients with cardiovascular disease by Liakou, P., Maughan, R., Pericleous, C., Mason, P., Mason, J.C.

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META-ANALYSIS OF 17 CLINICAL TRIALS USING OMEGA-3 FATTY ACIDS IN PATIENTS WITH CARDIOVASCULAR DISEASE by Liakou, P, Mason, P, Maughan, R, Pericleous, C, Mason, J

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Molecular imaging of experimental atherosclerosis using anti-malondialdehyde-modified low-density lipoprotein humanised antibody fragment targeted nanoparticles by Hartley, A, Greene, M, Caga-Anan, M, Owen, S, Mullin, M, Pericleous, C, Scott, C, Mason, J, Haskard, D O, Khamis, R

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S77Modulatory effects of rheumatoid arthritis IGG on neutrophil activation: a potential role in RA-ILD by Khawaja, A A, Pericleous, C, Ripoll, V M, Booth, H L, Holmes, V, Mikolasch, T, Giles, I, Porter, J C

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S77 Modulatory effects of rheumatoid arthritis IGG on neutrophil activation: a potential role in RA-ILD by Khawaja, AA, Pericleous, C, Ripoll, VM, Booth, HL, Holmes, V, Mikolasch, T, Giles, I, Porter, JC

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S79 Localised hypoxia enhances neutrophil extravasation and activation in interstitial lung disease by Khawaja, AA, Sahota, J, Pericleous, C, Ripoll, VM, Chong, DLW, Azzopardi, G, Thomas, LW, Booth, HL, Groves, AM, Ashcroft, M, Giles, I, Porter, JC

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Antiphospholipid antibodies and neurological manifestations in acute COVID-19: A single-centre cross-sectional study by Benjamin, Laura A., Paterson, Ross W., Moll, Rachel, Pericleous, Charis, Brown, Rachel, Mehta, Puja R., Athauda, Dilan, Ziff, Oliver J., Heaney, Judith, Checkley, Anna M., Houlihan, Catherine F., Chou, Michael, Heslegrave, Amanda J., Chandratheva, Arvind, Michael, Benedict D., Blennow, Kaj, Vivekanandam, Vinojini, Foulkes, Alexander, Mummery, Catherine J., Lunn, Michael P., Keddie, Stephen, Spyer, Moira J., Mckinnon, Tom, Hart, Melanie, Carletti, Francesco, Jäger, Hans Rolf, Manji, Hadi, Zandi, Michael S., Werring, David J., Nastouli, Eleni, Simister, Robert, Solomon, Tom, Zetterberg, Henrik, Schott, Jonathan M., Cohen, Hannah, Efthymiou, Maria

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Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of  2-glycoprotein I in a mouse model of anti-phospholipid antibody-... by Pericleous, C., Ruiz-Limon, P., Romay-Penabad, Z., Marin, A. C., Garza-Garcia, A., Murfitt, L., Driscoll, P. C., Latchman, D. S., Isenberg, D. A., Giles, I., Ioannou, Y., Rahman, A., Pierangeli, S. S.

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BHPR: Audit and Clinical Evaluation 103. Dental Health in Children and Young Adults with Inflammatory Arthritis: Access to Dental Care by Donnelly, S., Hassell, A., Bearne, L., Hayes, J., Empson, B., Kemp, P., Richards, P., Hay, E., Jones, L. E., Hislop, K., Barbosa Boucas, S., Nichols, V. P., Coulson, N., Ryan, S.-J., Manning, V. L., Hurley, M., Kennedy, N., Koduri, G., Kumar, K., Chapman, S., Ferguson, A. M., Lempp, H., Arden, N., Laxminarayan, R., Gates, L., Hermsen, L., Terwee, C. B., vd Zwaard, B., Nicky Thomas, V., Cope, A., Weinman, J., Agarwal, S., Paul, L., Gill, J., Steultjens, M., Hensor, E. M., Redmond, A., Wakefield, R. J., Law, R.-J., Kraus, A., Porter, D., Gupta, M., Lockhart, J. C., Ferrell, W. R., Nicolaou, M., Lillicrap, M., Merkel, P. A., Watts, R. A., Watt, K. A., Grosart, R., Khurshid, M. A., Sheeran, T., Muether, M., Clunie, G., Belsey, J., Holbrook, J., Dogra, S., Rao Chaganti, S., Thompson, J., Prentice, A., Winder, N., Osmond, C., Davey Smith, G., Toms, T. E., Price, T., Davidson, J., Foster, H., McDonagh, J., King, D., Goulston, L., Culliford, D., Taylor, P., Sofat, N., Thomas, M. J., Jordan, N., Chaib, A., San Tan, R., Yin Wong, T., Julian, T., Yvonne Alexander, M., Hall, C., Butters, T., Hickman, R., Leung, M. H., Situnayake, D., Lazarus, M. N., Ehrenstein, M. R., Bell, A., Ray, D. W., Watson, K. D., Erb, N., Edwards, C. J., Pericleous, C., Garza-Garcia, A., De La Torre Ortega, I., Cambridge, G., Croca, S. C., Giles, I., Artim Esen, B., Haque, S.

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BSPAR ANNUAL CONFERENCE ABSTRACTS Oral presentations O1. The impact of modern management on outcomes of JIA compared with healthy controls by Lim, D., Todd, M., Kourtoglou, N., Gerasimidis, K., Gardner-Medwin, J., Watson, L., Tullus, K., Pilkington, C., Chesters, C., Marks, S. D., Newland, P., Jones, C., Beresford, M. W., O'Neill, P., Lee, H., McErlane, F., Beresford, M., Baildam, E., Alice Chieng, S. E., Davidson, J., Foster, H., Lunt, M., Wedderburn, L. R., Thomson, W., Hyrich, K. L., Kavirayani, A., Thyagarajan, M. S., Ellis, J., Helen Strike, C. N. S., Ramanan, A. V., Fowlie, P., Walsh, J., Carline, T., Santos, D., Brimlow, K. W., Rangaraj, S., Grant, C., Little, J., Hinchcliffe, A., Dick, A., Ramanan, A., Ekdawy, D., Nagra, G., Camina, N., Edgerton, J., Choi, J., Lamb, K., Hawley, D., Cruikshank, M., Sen, E., Leone, V., Dunkley, L., McMahon, A.-M., Bale, P., Armon, K., Amin, T., Wood, M., Davies, R., Southwood, T. R., Kearsley-Fleet, L., Mowbray, K., Agarwal, M., Smith, E., Gray, W., Taylor-Robinson, D., Morgan, T., Gohar, F., Artim-Esen, B., Radziszewska, A., Pericleous, C., Rahman, A., Giles, I., Ioannou, Y., Jashek, D., Mosley, E., Arnold, K., Russell, N.-J., Roderick, M., Russell, N., Smith, N. S. M., Wilson, N., Chan, M., Hardy, E., Rapley, T., Hensman, P., Wraith, J. E., Clarkson, J., McVitty, C., Hughes, D. H., Martin, N., Warrier, K., Abinun, M., Jandial, S., O'Leary, D., Staunton, D., Lowry, C., McSweeney, N., Friswell, M., Walsh, A., Raja, A.

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BSPAR ANNUAL CONFERENCE ABSTRACTS Oral presentations O1. The impact of modern management on outcomes of JIA compared with healthy controls by Lim, D., Todd, M., Kourtoglou, N., Gerasimidis, K., Gardner-Medwin, J., Watson, L., Tullus, K., Pilkington, C., Chesters, C., Marks, S. D., Newland, P., Jones, C., Beresford, M. W., O'Neill, P., Lee, H., McErlane, F., Beresford, M., Baildam, E., Alice Chieng, S. E., Davidson, J., Foster, H., Lunt, M., Wedderburn, L. R., Thomson, W., Hyrich, K. L., Kavirayani, A., Thyagarajan, M. S., Ellis, J., Helen Strike, C. N. S., Ramanan, A. V., Fowlie, P., Walsh, J., Carline, T., Santos, D., Brimlow, K. W., Rangaraj, S., Grant, C., Little, J., Hinchcliffe, A., Dick, A., Ramanan, A., Ekdawy, D., Nagra, G., Camina, N., Edgerton, J., Choi, J., Lamb, K., Hawley, D., Cruikshank, M., Sen, E., Leone, V., Dunkley, L., McMahon, A.-M., Bale, P., Armon, K., Amin, T., Wood, M., Davies, R., Southwood, T. R., Kearsley-Fleet, L., Mowbray, K., Agarwal, M., Smith, E., Gray, W., Taylor-Robinson, D., Morgan, T., Gohar, F., Artim-Esen, B., Radziszewska, A., Pericleous, C., Rahman, A., Giles, I., Ioannou, Y., Jashek, D., Mosley, E., Arnold, K., Russell, N.-J., Roderick, M., Russell, N., Smith, N. S. M., Wilson, N., Chan, M., Hardy, E., Rapley, T., Hensman, P., Wraith, J. E., Clarkson, J., McVitty, C., Hughes, D. H., Martin, N., Warrier, K., Abinun, M., Jandial, S., O'Leary, D., Staunton, D., Lowry, C., McSweeney, N., Friswell, M., Walsh, A., Raja, A.

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In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of beta 2-glycoprotein I: proof of concept by Ioannou, Y, Romay-Penabad, Z, Pericleous, C, Giles, I, PAPALARDO, E, Vargas, G, SHILAGARD, T, Latchman, D S, Isenberg, Da, Rahman, A, Pierangeli, S

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Oral abstracts 3: RA Treatment and outcomes O13. Validation of jadas in all subtypes of juvenile idiopathic arthritis in a clinical setting by Beresford, M. W., Baildam, E. M., Davidson, J., Wedderburn, L., Nikiphorou, E., Carpenter, L., Kiely, P., Walsh, D., Dixey, J., Kapoor, S. R., Filer, A., Fitzpatrick, M., Taylor, P. C., Young, S. P., Dougados, M., Amital, H., Conaghan, P., Martin-Mola, E., Nasonov, E., Schett, G., Troum, O., Veldi, T., Huizinga, T., Durez, P., Richards, H. B., Supronik, J., Dokoupilova, E., Aelion, J. A., Kellner, H., Ligozio, G., Mpofu, S., Kavanaugh, A., Emery, P., Fleischmann, R., Pavelka, K., Redden, L., Smolen, J. S., Wilkie, R., Tajar, A., McBeth, J., Bowen, C. J., Gates, L., Culliford, D., Edwards, C. J., Ryan, S., Siddle, H. J., Waxman, R., Alcacer-Pitarch, B., Williams, R., Law, R.-J., Jones, J., Markland, D., Bruce, I., Giles, I., Rahman, A., Ioannou, Y., Warrell, C. E., Dobarro, D., Handler, C., Schreiber, B. E., Coghlan, J. G., Woodhead, F., Bunn, C., Abraham, D., Desai, S., du Bois, R., McHugh, N., Abignano, G., Woods, D., Meekings, A., McGonagle, D., Del Galdo, F., Mitchell, S., Bombardieri, M., Sutcliffe, N., Pitzalis, C., Lanyon, P., Cooper, A., Vadivelu, S., Lendrem, D., Foggo, H., Ng, W.-F., Shekar, P., Bailey, A.-M., Thompson, L., Salisbury, C., Foster, N. E., Coast, J., Hall, J., Kaur, S., Paskins, Z., Sanders, T., Croft, P. R., Hassell, A. B., Jinks, C., Peat, G., Monk, H. L., Mallen, C., Hider, S. L., Hayward, R.

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Muscle disorders 111. The impact of fatigue in patients with idiopathic inflammatory myopathy: a mixed method study by Sayer, A. A., Worsley, P. R., Srivastava, R. N., Elbaz, A., Mor, A., Norman, D., Collins, J., Milner, P. I., Jordan, K. P., Chapman, R., Walsh, D., Zhang, W., Doherty, S., Hathway, G., Mann, K. D., Mellon, S. J., Grieve, S., Gorodkin, R., Bukhari, M., Rajak, R., Stephenson, S., Morrison, L., Tobias, J. H., Lee, D. M., Claessens, F., Punab, M., Harvey, N. C., Robinson, S. M., Godfrey, K. M., Bridges, M., Patil, P., Fox, A., Nisar, S., Armon, K., Beresford, M. W., Lunt, M., Scaife, C., McAllister, C., Duncan, M., Penn, H., Pakozdi, A., Green, D. J., Hider, S. L., Palmer, M., Williamson, L., Done, J., Smolen, J. S., Emery, P., van der Heijde, D., Mozaffarian, N., Deeming, A., Rankin, E., Jordan, A., Joy, C., Borg, F. A., Bell, G. M., Hilkens, C. M., Banik, S., Withrington, R., Morrison, I., Thompson, H., Kinderlerer, A., Ferrari, M., Obrenovic, K., Erb, N., Justice, E., Gaillez, C., Hassanzadeh, R., Mangan, C., Timoshanko, J., Dougados, M., Schiff, M., Kaine, J. L., Delaet, I., McCrae, F., Teng, J., van Staa, T., Sarzi-Puttini, P., Andrianakos, A., Desjuzeur, M.-L., Gemmen, E. K., Paudyal, P., MacPherson, H., Sim, J., Ernst, E., Hsia, E., Doyle, M., Hassell, A., Simpson, G., Samborski, W., Bernasconi, C., Weinblatt, M., Kermik, J., McWilliams, D., Rao, V., Klearman, M., Lee, J., Thant, K. Z., Williams, J., Ramakrishnan, S. A.

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Basic science 232. Certolizumab pegol prevents pro-inflammatory alterations in endothelial cell function by Alexander, Y., Stone, M., Wang, E., Williams, A. S., Moots, R. J., Edwards, S. W., Chapman, V., Young, S. P., Kollnberger, S., Bowness, P., Giles, J. L., McHugh, K., Nayar, S., Oreffo, R. O., Wilkinson, M., Abozaid, H. S., Jayaraj, D. M., Choy, E. H., Hickling, M., Amos, N., Haddock, G., Cross, A. K., Corrigall, V., Ferrell, W. R., Mehta, P., Sharp, C. A., Wood, E. F., Abdulkader, R., Banik, S., Chana, J. K., Ayalew, Y., Khattak, F., Ng, N., Casey, M., Walker, D., Bateman, J., Davies, D., Walker-Bone, K., Gainsborough, N., Davies, U. M., Coady, D., Brown, D., Pendleton, N., Cordingley, L., Robinson, S. M., Godfrey, K. M., Sayer, A. A., Harvey, N. C., Low, A., Hyrich, K., Chitale, S., Estrach, C., Humphreys, J., Bunn, D., Macfarlane, G. J., Scott, I. C., Lewis, C. M., Cope, A., Spector, T., Herrick, A., Wilson, A., Hewlett, S., Morris, M., Cardy, C. M., Davies, C., Hakim, A. J., Jani, M., Rao, C., McLoughlin, Y., Else, S., Baguley, E., Husain, M. J., Brophy, S., Phillips, C. J., McLaren, J., Cooper, A., Marks, J., Gathany, T., Rutherford, M., Wilson, G., Johnson, P., Duncan, G., Adshead, R., Finlay, R., Fortune, F., Tarelli, E., Ioannou, J., Oomatia, A., Petri, M., Stewart, K., Sutton, E. J., Yee, C.-S., D'Cruz, D., Garza-Garcia, A., Driscoll, P. C., Kuvikova, I., Brown, N., Stockton, M., Kindness, K., Watts, R.

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