Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses by Grigorev, Kirill, Nelson, Theodore M, Overbey, Eliah G, Houerbi, Nadia, Kim, JangKeun, Najjar, Deena, Damle, Namita, Afshin, Evan E, Ryon, Krista A, Thierry-Mieg, Jean, Thierry-Mieg, Danielle, Melnick, Ari M, Mateus, Jaime, Mason, Christopher E

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Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA) by Overbey, Eliah G, Ryon, Krista, Kim, JangKeun, Tierney, Braden T, Klotz, Remi, Ortiz, Veronica, Mullane, Sean, Schmidt, Julian C, MacKay, Matthew, Damle, Namita, Najjar, Deena, Matei, Irina, Patras, Laura, Garcia Medina, J. Sebastian, Kleinman, Ashley S, Wain Hirschberg, Jeremy, Proszynski, Jacqueline, Narayanan, S. Anand, Schmidt, Caleb M, Afshin, Evan E, Innes, Lucinda, Saldarriaga, Mateo Mejia, Schmidt, Michael A, Granstein, Richard D, Shirah, Bader, Yu, Min, Lyden, David, Mateus, Jaime, Mason, Christopher E

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Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight by Kim, JangKeun, Tierney, Braden T, Overbey, Eliah G, Dantas, Ezequiel, Fuentealba, Matias, Park, Jiwoon, Narayanan, S. Anand, Wu, Fei, Najjar, Deena, Chin, Christopher R, Meydan, Cem, Loy, Conor, Mathyk, Begum, Klotz, Remi, Ortiz, Veronica, Nguyen, Khiem, Ryon, Krista A, Damle, Namita, Houerbi, Nadia, Patras, Laura I, Schanzer, Nathan, Hutchinson, Gwyneth A, Foox, Jonathan, Bhattacharya, Chandrima, Mackay, Matthew, Afshin, Evan E, Hirschberg, Jeremy Wain, Kleinman, Ashley S, Schmidt, Julian C, Schmidt, Caleb M, Schmidt, Michael A, Beheshti, Afshin, Matei, Irina, Lyden, David, Mullane, Sean, Asadi, Amran, Lenz, Joan S, Mzava, Omary, Yu, Min, Ganesan, Saravanan, De Vlaminck, Iwijn, Melnick, Ari M, Barisic, Darko, Winer, Daniel A, Zwart, Sara R, Crucian, Brian E, Smith, Scott M, Mateus, Jaime, Furman, David, Mason, Christopher E

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Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight by Houerbi, Nadia, Kim, JangKeun, Overbey, Eliah G, Batra, Richa, Schweickart, Annalise, Patras, Laura, Lucotti, Serena, Ryon, Krista A, Najjar, Deena, Meydan, Cem, Damle, Namita, Chin, Christopher, Narayanan, S. Anand, Guarnieri, Joseph W, Widjaja, Gabrielle, Beheshti, Afshin, Tobias, Gabriel, Vatter, Fanny, Hirschberg, Jeremy Wain, Kleinman, Ashley, Afshin, Evan E, MacKay, Matthew, Chen, Qiuying, Miller, Dawson, Gajadhar, Aaron S, Williamson, Lucy, Tandel, Purvi, Yang, Qiu, Chu, Jessica, Benz, Ryan, Siddiqui, Asim, Hornburg, Daniel, Gross, Steven, Shirah, Bader, Krumsiek, Jan, Mateus, Jaime, Mao, Xiao, Matei, Irina, Mason, Christopher E

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Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight by Park, Jiwoon, Overbey, Eliah G, Narayanan, S. Anand, Kim, JangKeun, Tierney, Braden T, Damle, Namita, Najjar, Deena, Ryon, Krista A, Proszynski, Jacqueline, Kleinman, Ashley, Hirschberg, Jeremy Wain, MacKay, Matthew, Afshin, Evan E, Granstein, Richard, Gurvitch, Justin, Hudson, Briana M, Rininger, Aric, Mullane, Sean, Church, Sarah E, Meydan, Cem, Church, George, Beheshti, Afshin, Mateus, Jaime, Mason, Christopher E

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Spaceflight influences gene expression, photoreceptor integrity, and oxidative stress-related damage in the murine retina by Overbey, Eliah G, da Silveira, Willian Abraham, Stanbouly, Seta, Nishiyama, Nina C, Roque-Torres, Gina D, Pecaut, Michael J, Zawieja, David Carl, Wang, Charles, Willey, Jeffrey S, Delp, Michael D, Hardiman, Gary, Mao, Xiao Wen

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Immunological and Hematological Outcomes Following Protracted Low Dose/Low Dose Rate Ionizing Radiation and Simulated Microgravity by Paul, Amber M, Overbey, Eliah G, Silveira, Willian A da, Szewczyk, Nathaniel, Nishiyama, Nina C, Pecaut, Michael J, Galazka, Jonathan M, Mao, Xiao Wen

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Mammalian and Invertebrate Models as Complementary Tools for Gaining Mechanistic Insight on Muscle Responses to Spaceflight by Cahill, Thomas, Cope, Henry, Bass, Joseph J., Overbey, Eliah G., Gilbert, Rachel, da Silveira, Willian Abraham, Paul, Amber M., Mishra, Tejaswini, Herranz, Raúl, Reinsch, Sigrid S., Costes, Sylvain V., Hardiman, Gary, Szewczyk, Nathaniel J., Tahimic, Candice G. T.

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Molecular and physiological changes in the SpaceX Inspiration4 civilian crew by Jones, Christopher W., Overbey, Eliah G., Lacombe, Jerome, Ecker, Adrian J., Meydan, Cem, Ryon, Krista, Tierney, Braden, Damle, Namita, MacKay, Matthew, Afshin, Evan E., Foox, Jonathan, Park, Jiwoon, Nelson, Theodore M., Suhail Mohamad, Mir, Byhaqui, Syed Gufran Ahmad, Aslam, Burhan, Tali, Ummer Akbar, Nisa, Liaqun, Menon, Priya V., Patel, Chintan O., Khan, Sharib A., Ebert, Doug J., Everson, Aaron, Schubert, Michael C., Ali, Nabila N., Sarma, Mallika S., Kim, JangKeun, Houerbi, Nadia, Grigorev, Kirill, Garcia Medina, J. Sebastian, Summers, Alexander J., Gu, Jian, Altin, John A., Fattahi, Ali, Hirzallah, Mohammad I., Wu, Jimmy H., Stahn, Alexander C., Beheshti, Afshin, Klotz, Remi, Ortiz, Veronica, Yu, Min, Patras, Laura, Matei, Irina, Lyden, David, Melnick, Ari, Banerjee, Neil, Mullane, Sean, Kleinman, Ashley S., Loesche, Michael, Menon, Anil S., Donoviel, Dorit B., Urquieta, Emmanuel, Mateus, Jaime, Sargsyan, Ashot E., Shelhamer, Mark, Zenhausern, Frederic, Bershad, Eric M., Basner, Mathias, Mason, Christopher E.

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A second space age spanning omics, platforms and medicine across orbits by Mason, Christopher E., Green, James, Adamopoulos, Konstantinos I., Afshin, Evan E., Baechle, Jordan J., Basner, Mathias, Bailey, Susan M., Bielski, Luca, Borg, Josef, Borg, Joseph, Broddrick, Jared T., Burke, Marissa, Caicedo, Andrés, Castañeda, Verónica, Chatterjee, Subhamoy, Chin, Christopher R., Church, George, Costes, Sylvain V., De Vlaminck, Iwijn, Desai, Rajeev I., Dhir, Raja, Diaz, Juan Esteban, Etlin, Sofia M., Feinstein, Zachary, Furman, David, Garcia-Medina, J. Sebastian, Garrett-Bakelman, Francine, Giacomello, Stefania, Gupta, Anjali, Hassanin, Amira, Houerbi, Nadia, Irby, Iris, Javorsky, Emilia, Jirak, Peter, Jones, Christopher W., Kamal, Khaled Y., Kangas, Brian D., Karouia, Fathi, Kim, JangKeun, Kim, Joo Hyun, Kleinman, Ashley S., Lam, Try, Lawler, John M., Lee, Jessica A., Limoli, Charles L., Lucaci, Alexander, MacKay, Matthew, McDonald, J. Tyson, Melnick, Ari M., Meydan, Cem, Mieczkowski, Jakub, Muratani, Masafumi, Najjar, Deena, Othman, Mariam A., Overbey, Eliah G., Paar, Vera, Park, Jiwoon, Paul, Amber M., Perdyan, Adrian, Proszynski, Jacqueline, Reynolds, Robert J., Ronca, April E., Rubins, Kate, Ryon, Krista A., Sanders, Lauren M., Glowe, Patricia Savi, Shevde, Yash, Schmidt, Michael A., Scott, Ryan T., Shirah, Bader, Sienkiewicz, Karolina, Sierra, Maria A., Siew, Keith, Theriot, Corey A., Tierney, Braden T., Venkateswaran, Kasthuri, Hirschberg, Jeremy Wain, Walsh, Stephen B., Walter, Claire, Winer, Daniel A., Yu, Min, Zea, Luis, Mateus, Jaime, Beheshti, Afshin

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Spatiotemporal expression and control of haemoglobin in space by Borg, Josef, Loy, Conor, Kim, JangKeun, Buhagiar, Alfred, Chin, Christopher, Damle, Namita, De Vlaminck, Iwijn, Felice, Alex, Liu, Tammy, Matei, Irina, Meydan, Cem, Muratani, Masafumi, Mzava, Omary, Overbey, Eliah, Ryon, Krista A, Smith, Scott M, Tierney, Braden T, Trudel, Guy, Zwart, Sara R, Beheshti, Afshin, Mason, Christopher E, Borg, Joseph

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Protective alleles and precision healthcare in crewed spaceflight by Rutter, Lindsay A, MacKay, Matthew J, Cope, Henry, Szewczyk, Nathaniel J, Kim, JangKeun, Overbey, Eliah, Tierney, Braden T, Muratani, Masafumi, Lamm, Ben, Bezdan, Daniela, Paul, Amber M, Schmidt, Michael A, Church, George M, Giacomello, Stefania, Mason, Christopher E

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Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight by Wu, Fei, Du, Huixun, Overbey, Eliah, Kim, JangKeun, Makhijani, Priya, Martin, Nicolas, Lerner, Chad A, Nguyen, Khiem, Baechle, Jordan, Valentino, Taylor R, Fuentealba, Matias, Bartleson, Juliet M, Halaweh, Heather, Winer, Shawn, Meydan, Cem, Garrett-Bakelman, Francine, Sayed, Nazish, Melov, Simon, Muratani, Masafumi, Gerencser, Akos A, Kasler, Herbert G, Beheshti, Afshin, Mason, Christopher E, Furman, David, Winer, Daniel A

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The Space Omics and Medical Atlas (SOMA) and international astronaut biobank by Overbey, Eliah G., Tierney, Braden T., Park, Jiwoon, Houerbi, Nadia, Lucaci, Alexander G., Garcia Medina, Sebastian, Damle, Namita, Najjar, Deena, Grigorev, Kirill, Afshin, Evan E., Ryon, Krista A., Sienkiewicz, Karolina, Patras, Laura, Klotz, Remi, Ortiz, Veronica, MacKay, Matthew, Schweickart, Annalise, Chin, Christopher R., Sierra, Maria A., Valenzuela, Matias F., Dantas, Ezequiel, Nelson, Theodore M., Cekanaviciute, Egle, Deards, Gabriel, Foox, Jonathan, Narayanan, S. Anand, Schmidt, Caleb M., Schmidt, Julian C., Mullane, Sean, Tigchelaar, Seth Stravers, Levitte, Steven, Bhattacharya, Chandrima, Lucotti, Serena, Wain Hirschberg, Jeremy, Proszynski, Jacqueline, Burke, Marissa, Kleinman, Ashley S., Butler, Daniel J., Loy, Conor, Mzava, Omary, Lenz, Joan, Paul, Doru, Mozsary, Christopher, Sanders, Lauren M., Taylor, Lynn E., Patel, Chintan O., Khan, Sharib A., Suhail Mohamad, Mir, Byhaqui, Syed Gufran Ahmad, Aslam, Burhan, Gajadhar, Aaron S., Tandel, Purvi, Yang, Qiu, Chu, Jessica, Benz, Ryan W., Siddiqui, Asim, Hornburg, Daniel, Blease, Kelly, Moreno, Juan, Boddicker, Andrew, Zhao, Junhua, Lajoie, Bryan, Scott, Ryan T., Gilbert, Rachel R., Lai Polo, San-huei, Kruglyak, Semyon, Levy, Shawn, Ariyapala, Ishara, Beer, Joanne, Zhang, Bingqing, Hudson, Briana M., Rininger, Aric, Church, Sarah E., Beheshti, Afshin, Church, George M., Crucian, Brian E., Zwart, Sara R., Lyden, David C., Garrett-Bakelman, Francine, Krumsiek, Jan, Chen, Qiuying, Miller, Dawson, Shuga, Joe, Nemec, Corey, Trudel, Guy, Pelchat, Martin, Laneuville, Odette, De Vlaminck, Iwijn, Bolton, Kelly L., Bailey, Susan M., Granstein, Richard, Furman, David, Melnick, Ari M., Costes, Sylvain V., Shirah, Bader, Yu, Min, Menon, Anil S., Mateus, Jaime, Meydan, Cem, Mason, Christopher E.

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Space radiation damage rescued by inhibition of key spaceflight associated miRNAs by McDonald, J. Tyson, Kim, JangKeun, Farmerie, Lily, Johnson, Meghan L, Trovao, Nidia S, Arif, Shehbeel, Siew, Keith, Tsoy, Sergey, Bram, Yaron, Park, Jiwoon, Overbey, Eliah, Ryon, Krista, Haltom, Jeffrey, Singh, Urminder, Enguita, Francisco J, Zaksas, Victoria, Guarnieri, Joseph W, Topper, Michael, Wallace, Douglas C, Meydan, Cem, Baylin, Stephen, Meller, Robert, Muratani, Masafumi, Porterfield, D. Marshall, Kaufman, Brett, Mori, Marcelo A, Walsh, Stephen B, Sigaudo-Roussel, Dominique, Mebarek, Saida, Bottini, Massimo, Marquette, Christophe A, Wurtele, Eve Syrkin, Schwartz, Robert E, Galeano, Diego, Mason, Christopher E, Grabham, Peter, Beheshti, Afshin

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Transcriptomes of an Array of Chicken Ovary, Intestinal, and Immune Cells and Tissues by Overbey, Eliah G., Ng, Theros T., Catini, Pietro, Griggs, Lisa M., Stewart, Paul, Tkalcic, Suzana, Hawkins, R. David, Drechsler, Yvonne

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Enhancer Chromatin and 3D Genome Architecture Changes from Naive to Primed Human Embryonic Stem Cell States by Battle, Stephanie L., Doni Jayavelu, Naresh, Azad, Robert N., Hesson, Jennifer, Ahmed, Faria N., Overbey, Eliah G., Zoller, Joseph A., Mathieu, Julie, Ruohola-Baker, Hannele, Ware, Carol B., Hawkins, R. David

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Aging and putative frailty biomarkers are altered by spaceflight by Camera, Andrea, Tabetah, Marshall, Castañeda, Veronica, Kim, JangKeun, Galsinh, Aman Singh, Haro-Vinueza, Alissen, Salinas, Ivonne, Seylani, Allen, Arif, Shehbeel, Das, Saswati, Mori, Marcelo A, Carano, Anthony, de Oliveira, Lorraine Christine, Muratani, Masafumi, Barker, Richard, Zaksas, Victoria, Goel, Chirag, Dimokidis, Eleni, Taylor, Deanne M, Jeong, Jisu, Overbey, Eliah, Meydan, Cem, Porterfield, D. Marshall, Díaz, Juan Esteban, Caicedo, Andrés, Schisler, Jonathan C, Laiakis, Evagelia C, Mason, Christopher E, Kim, Man S, Karouia, Fathi, Szewczyk, Nathaniel J, Beheshti, Afshin

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Inspiration4 data access through the NASA Open Science Data Repository by Sanders, Lauren M, Grigorev, Kirill A, Scott, Ryan T, Saravia-Butler, Amanda M, Polo, San-Huei Lai, Gilbert, Rachel, Overbey, Eliah G, Kim, JangKeun, Mason, Christopher E, Costes, Sylvain V

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NASA GeneLab RNA-seq consensus pipeline: Standardized processing of short-read RNA-seq data by Overbey, Eliah G., Saravia-Butler, Amanda M., Zhang, Zhe, Rathi, Komal S., Fogle, Homer, da Silveira, Willian A., Barker, Richard J., Bass, Joseph J., Beheshti, Afshin, Berrios, Daniel C., Blaber, Elizabeth A., Cekanaviciute, Egle, Costa, Helio A., Davin, Laurence B., Fisch, Kathleen M., Gebre, Samrawit G., Geniza, Matthew, Gilbert, Rachel, Gilroy, Simon, Hardiman, Gary, Herranz, Raúl, Kidane, Yared H., Kruse, Colin P.S., Lee, Michael D., Liefeld, Ted, Lewis, Norman G., McDonald, J. Tyson, Meller, Robert, Mishra, Tejaswini, Perera, Imara Y., Ray, Shayoni, Reinsch, Sigrid S., Rosenthal, Sara Brin, Strong, Michael, Szewczyk, Nathaniel J., Tahimic, Candice G.T., Taylor, Deanne M., Vandenbrink, Joshua P., Villacampa, Alicia, Weging, Silvio, Wolverton, Chris, Wyatt, Sarah E., Zea, Luis, Costes, Sylvain V., Galazka, Jonathan M.

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