Linked selection and recombination rate variation drive the evolution of the genomic landscape of differentiation across the speciation continuum of Ficedula flycatchers

by Burri, Reto, Nater, Alexander, Kawakami, Takeshi, Mugal, Carina F, Olason, Pall I, Smeds, Linnea, Suh, Alexander, Dutoit, Ludovic, Bureš, Stanislav, Garamszegi, Laszlo Z, Hogner, Silje, Moreno, Juan, Qvarnström, Anna, Ružić, Milan, Sæther, Stein-Are, Sætre, Glenn-Peter, Török, Janos, Ellegren, Hans
Published in Genome research

The sequences of 150,119 genomes in the UK Biobank

by Halldorsson, Bjarni V, Eggertsson, Hannes P, Moore, Kristjan H S, Hauswedell, Hannes, Eiriksson, Ogmundur, Ulfarsson, Magnus O, Palsson, Gunnar, Hardarson, Marteinn T, Oddsson, Asmundur, Jensson, Brynjar O, Kristmundsdottir, Snaedis, Sigurpalsdottir, Brynja D, Stefansson, Olafur A, Beyter, Doruk, Holley, Guillaume, Tragante, Vinicius, Gylfason, Arnaldur, Olason, Pall I, Zink, Florian, Asgeirsdottir, Margret, Sverrisson, Sverrir T, Sigurdsson, Brynjar, Gudjonsson, Sigurjon A, Sigurdsson, Gunnar T, Halldorsson, Gisli H, Sveinbjornsson, Gardar, Norland, Kristjan, Styrkarsdottir, Unnur, Magnusdottir, Droplaug N, Snorradottir, Steinunn, Kristinsson, Kari, Sobech, Emilia, Jonsson, Helgi, Geirsson, Arni J, Olafsson, Isleifur, Jonsson, Palmi, Pedersen, Ole Birger, Erikstrup, Christian, Brunak, Søren, Ostrowski, Sisse Rye, Thorleifsson, Gudmar, Jonsson, Frosti, Melsted, Pall, Jonsdottir, Ingileif, Rafnar, Thorunn, Holm, Hilma, Stefansson, Hreinn, Saemundsdottir, Jona, Gudbjartsson, Daniel F, Magnusson, Olafur T, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Jonsson, Hakon, Sulem, Patrick, Stefansson, Kari
Published in Nature (London)

Demographic divergence history of pied flycatcher and collared flycatcher inferred from whole-genome re-sequencing data

by Nadachowska-Brzyska, Krystyna, Burri, Reto, Olason, Pall I, Kawakami, Takeshi, Smeds, Linnéa, Ellegren, Hans
Published in PLoS genetics

The genomic landscape of species divergence in Ficedula flycatchers

by ELLEGREN, Hans, SMEDS, Linnéa, UEBBING, Severin, WOLF, Jochen B. W, BURRI, Reto, OLASON, Pall I, BACKSTRÖM, Niclas, KAWAKAMI, Takeshi, KÜNSTNER, Axel, MÄKINEN, Hannu, NADACHOWSKA-BRZYSKA, Krystyna, QVARNSTRÖM, Anna
Published in Nature (London)

A human phenome-interactome network of protein complexes implicated in genetic disorders

by Brunak, Søren, Lage, Kasper, Karlberg, E Olof, Størling, Zenia M, Ólason, Páll Í, Pedersen, Anders G, Rigina, Olga, Hinsby, Anders M, Tümer, Zeynep, Pociot, Flemming, Tommerup, Niels, Moreau, Yves
Published in Nature biotechnology

A whole-genome sequenced control population in northern Sweden reveals subregional genetic differences

by Svensson, Daniel, Rentoft, Matilda, Dahlin, Anna M, Lundholm, Emma, Olason, Pall I, Sjödin, Andreas, Nylander, Carin, Melin, Beatrice S, Trygg, Johan, Johansson, Erik
Published in PloS one

Sarek: A portable workflow for whole-genome sequencing analysis of germline and somatic variants [version 1; peer review: 2 approved]

by Garcia, Maxime, Juhos, Szilveszter, Larsson, Malin, Olason, Pall I, Martin, Marcel, Eisfeldt, Jesper, DiLorenzo, Sebastian, Sandgren, Johanna, Díaz De Ståhl, Teresita, Ewels, Philip, Wirta, Valtteri, Nistér, Monica, Käller, Max, Nystedt, Björn
Published in F1000 research

Sequence variants affecting the genome-wide rate of germline microsatellite mutations

by Kristmundsdottir, Snaedis, Jonsson, Hakon, Hardarson, Marteinn T, Palsson, Gunnar, Beyter, Doruk, Eggertsson, Hannes P, Gylfason, Arnaldur, Sveinbjornsson, Gardar, Holley, Guillaume, Stefansson, Olafur A, Halldorsson, Gisli H, Olafsson, Sigurgeir, Arnadottir, Gudny A, Olason, Pall I, Eiriksson, Ogmundur, Masson, Gisli, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Sulem, Patrick, Helgason, Agnar, Gudbjartsson, Daniel F, Halldorsson, Bjarni V, Stefansson, Kari
Published in Nature communications

A geographically matched control population efficiently limits the number of candidate disease-causing variants in an unbiased whole-genome analysis

by Rentoft, Matilda, Svensson, Daniel, Sjödin, Andreas, Olason, Pall I, Sjöström, Olle, Nylander, Carin, Osterman, Pia, Sjögren, Rickard, Netotea, Sergiu, Wibom, Carl, Cederquist, Kristina, Chabes, Andrei, Trygg, Johan, Melin, Beatrice S, Johansson, Erik
Published in PloS one

A meta-analysis uncovers the first sequence variant conferring risk of Bell's palsy

by Skuladottir, Astros Th, Bjornsdottir, Gyda, Thorleifsson, Gudmar, Walters, G Bragi, Nawaz, Muhammad Sulaman, Moore, Kristjan Helgi Swerford, Olason, Pall I, Thorgeirsson, Thorgeir E, Sigurpalsdottir, Brynja, Sveinbjornsson, Gardar, Eggertsson, Hannes P, Magnusson, Sigurdur H, Oddsson, Asmundur, Bjornsdottir, Anna, Vikingsson, Arnor, Sveinsson, Olafur A, Hrafnsdottir, Maria G, Sigurdardottir, Gudrun R, Halldorsson, Bjarni V, Hansen, Thomas Folkmann, Paarup, Helene, Erikstrup, Christian, Nielsen, Kaspar, Klokker, Mads, Bruun, Mie Topholm, Sorensen, Erik, Banasik, Karina, Burgdorf, Kristoffer S, Pedersen, Ole Birger, Ullum, Henrik, Jonsdottir, Ingileif, Stefansson, Hreinn, Stefansson, Kari
Published in Scientific reports

Author Correction: Germline variants at SOHLH2 influence multiple myeloma risk

by Duran-Lozano, Laura, Thorleifsson, Gudmar, Lopez de Lapuente Portilla, Aitzkoa, Niroula, Abhishek, Went, Molly, Thodberg, Malte, Pertesi, Maroulio, Ajore, Ram, Cafaro, Caterina, Olason, Pall I., Stefansdottir, Lilja, Bragi Walters, G., Halldorsson, Gisli H., Turesson, Ingemar, Kaiser, Martin F., Weinhold, Niels, Abildgaard, Niels, Andersen, Niels Frost, Mellqvist, Ulf-Henrik, Waage, Anders, Juul-Vangsted, Annette, Thorsteinsdottir, Unnur, Hansson, Markus, Houlston, Richard, Rafnar, Thorunn, Stefansson, Kari, Nilsson, Björn
Published in Blood cancer journal (New York)

Sarek: A portable workflow for whole-genome sequencing analysis of germline and somatic variants [version 2; peer review: 2 approved]

by Garcia, Maxime, Juhos, Szilveszter, Larsson, Malin, Olason, Pall I, Martin, Marcel, Eisfeldt, Jesper, DiLorenzo, Sebastian, Sandgren, Johanna, Díaz De Ståhl, Teresita, Ewels, Philip, Wirta, Valtteri, Nistér, Monica, Käller, Max, Nystedt, Björn
Published in F1000 research

Integrative analysis for finding genes and networks involved in diabetes and other complex diseases

by Bergholdt, Regine, Størling, Zenia M, Lage, Kasper, Karlberg, E Olof, Olason, Páll I, Aalund, Mogens, Nerup, Jørn, Brunak, Søren, Workman, Christopher T, Pociot, Flemming
Published in Genome Biology

Parental origin of sequence variants associated with complex diseases

by Gudjonsson, Sigurjon A, Sigurdsson, Helgi, Kristinsson, Kari Th, Sigurdsson, Asgeir, Hreidarsson, Astradur B, Masson, Gisli, Ferguson-Smith, Anne C, Frigge, Michael L, Jonsson, Thorvaldur, Stacey, Simon N, Olafsson, Jon H, Benediktsdottir, Kristrun R, Gudbjartsson, Daniel F, Besenbacher, Soren, Gylfason, Arnaldur, Sigurgeirsson, Bardur, Olason, Pall I, Sverrisson, Sverrir, Stefansson, Kari, Johannsson, Oskar Th, Thorsteinsdottir, Unnur, Benediktsson, Rafn, Thorleifsson, Gudmar, Kong, Augustine, Steinthorsdottir, Valgerdur, Sulem, Patrick, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Sigurdsson, Gunnar
Published in Nature (London)

Large-scale plasma proteomics comparisons through genetics and disease associations

by Eldjarn, Grimur Hjorleifsson, Ferkingstad, Egil, Lund, Sigrun H, Helgason, Hannes, Magnusson, Olafur Th, Gunnarsdottir, Kristbjorg, Olafsdottir, Thorunn A, Halldorsson, Bjarni V, Olason, Pall I, Zink, Florian, Gudjonsson, Sigurjon A, Sveinbjornsson, Gardar, Magnusson, Magnus I, Helgason, Agnar, Oddsson, Asmundur, Halldorsson, Gisli H, Magnusson, Magnus K, Saevarsdottir, Saedis, Eiriksdottir, Thjodbjorg, Masson, Gisli, Stefansson, Hreinn, Jonsdottir, Ingileif, Holm, Hilma, Rafnar, Thorunn, Melsted, Pall, Saemundsdottir, Jona, Norddahl, Gudmundur L, Thorleifsson, Gudmar, Ulfarsson, Magnus O, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari
Published in Nature (London)

Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset

by Saevarsdottir, Saedis, Stefansdottir, Lilja, Sulem, Patrick, Thorleifsson, Gudmar, Ferkingstad, Egil, Rutsdottir, Gudrun, Glintborg, Bente, Westerlind, Helga, Grondal, Gerdur, Loft, Isabella C, Sorensen, Signe Bek, Lie, Benedicte Alexandra, Brink, Mikael, Arlestig, Lisbeth, Arnthorsson, Asgeir Orn, Baecklund, Eva, Banasik, Karina, Bank, Steffen, Bjorkman, Lena I, Ellingsen, Torkell, Erikstrup, Christian, Frei, Oleksandr, Gjertsson, Inger, Gudbjartsson, Daniel F, Gudjonsson, Sigurjon A, Halldorsson, Gisli H, Hendricks, Oliver, Hillert, Jan, Hogdall, Estrid, Jacobsen, Søren, Jensen, Dorte Vendelbo, Jonsson, Helgi Freyr, Kastbom, Alf, Kockum, Ingrid, Kristensen, Salome, Kristjansdottir, Helga, Larsen, Margit H, Linauskas, Asta, Hauge, Ellen-Margrethe, Loft, Anne G, Ludviksson, Bjorn R, Lund, Sigrun H, Markusson, Thorsteinn, Masson, Gisli, Melsted, Pall, Moore, Kristjan H S, Munk, Heidi, Nielsen, Kaspar R, Norddahl, Gudmundur L, Oddsson, Asmundur, Olafsdottir, Thorunn A, Olason, Pall I, Olsson, Tomas, Ostrowski, Sisse Rye, Hørslev-Petersen, Kim, Rognvaldsson, Solvi, Sanner, Helga, Silberberg, Gilad N, Stefansson, Hreinn, Sørensen, Erik, Sørensen, Inge J, Turesson, Carl, Bergman, Thomas, Alfredsson, Lars, Kvien, Tore Kristian, Brunak, Søren, Steinsson, Kristján, Andersen, Vibeke, Andreassen, Ole, Rantapää-Dahlqvist, Solbritt, Hetland, Merete Lund, Klareskog, Lars, Askling, Johan, Padyukov, Leonid, Pedersen, Ole Bv, Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Stefansson, Kari
Published in Annals of the rheumatic diseases

Disruption of the neurexin 1 gene is associated with schizophrenia

by Rujescu, Dan, Ingason, Andres, Cichon, Sven, Pietiläinen, Olli P.H., Barnes, Michael R., Toulopoulou, Timothea, Picchioni, Marco, Vassos, Evangelos, Ettinger, Ulrich, Bramon, Elvira, Murray, Robin, Ruggeri, Mirella, Tosato, Sarah, Bonetto, Chiara, Steinberg, Stacy, Sigurdsson, Engilbert, Sigmundsson, Thordur, Petursson, Hannes, Gylfason, Arnaldur, Olason, Pall I., Hardarsson, Gudmundur, Jonsdottir, Gudrun A., Gustafsson, Omar, Fossdal, Ragnheidur, Giegling, Ina, Möller, Hans-Jürgen, Hartmann, Annette M., Hoffmann, Per, Crombie, Caroline, Fraser, Gillian, Walker, Nicholas, Lonnqvist, Jouko, Suvisaari, Jaana, Tuulio-Henriksson, Annamari, Djurovic, Srdjan, Melle, Ingrid, Andreassen, Ole A., Hansen, Thomas, Werge, Thomas, Kiemeney, Lambertus A., Franke, Barbara, Veltman, Joris, Buizer-Voskamp, Jacobine E., Sabatti, Chiara, Ophoff, Roel A., Rietschel, Marcella, Nöthen, Markus M., Stefansson, Kari, Peltonen, Leena, St Clair, David, Stefansson, Hreinn, Collier, David A.
Published in Human molecular genetics

Loss-of-Function Variants in the Tumor-Suppressor Gene PTPN14 Confer Increased Cancer Risk

by Olafsdottir, Thorhildur, Stacey, Simon N, Sveinbjornsson, Gardar, Thorleifsson, Gudmar, Norland, Kristjan, Sigurgeirsson, Bardur, Thorisdottir, Kristin, Kristjansson, Arni Kjalar, Tryggvadottir, Laufey, Sarin, Kavita Y, Benediktsson, Rafn, Jonasson, Jon G, Sigurdsson, Asgeir, Jonasdottir, Aslaug, Kristmundsdottir, Snaedis, Jonsson, Hakon, Gylfason, Arnaldur, Oddsson, Asmundur, Fridriksdottir, Run, Gudjonsson, Sigurjon A, Zink, Florian, Lund, Sigrun H, Rognvaldsson, Solvi, Melsted, Pall, Steinthorsdottir, Valgerdur, Gudmundsson, Julius, Mikaelsdottir, Evgenia, Olason, Pall I, Stefansdottir, Lilja, Eggertsson, Hannes P, Halldorsson, Bjarni V, Thorsteinsdottir, Unnur, Agustsson, Tomas T, Olafsson, Karl, Olafsson, Jon H, Sulem, Patrick, Rafnar, Thorunn, Gudbjartsson, Daniel F, Stefansson, Kari
Published in Cancer research (Chicago, Ill.)

Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura

by Bjornsdottir, Gyda, Chalmer, Mona A, Stefansdottir, Lilja, Skuladottir, Astros Th, Einarsson, Gudmundur, Andresdottir, Margret, Beyter, Doruk, Ferkingstad, Egil, Gretarsdottir, Solveig, Halldorsson, Bjarni V, Halldorsson, Gisli H, Helgadottir, Anna, Helgason, Hannes, Hjorleifsson Eldjarn, Grimur, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Jonsdottir, Ingileif, Knowlton, Kirk U, Nadauld, Lincoln D, Lund, Sigrun H, Magnusson, Olafur Th, Melsted, Pall, Moore, Kristjan H. S, Oddsson, Asmundur, Olason, Pall I, Sigurdsson, Asgeir, Stefansson, Olafur A, Saemundsdottir, Jona, Sveinbjornsson, Gardar, Tragante, Vinicius, Unnsteinsdottir, Unnur, Walters, G. Bragi, Zink, Florian, Rødevand, Linn, Andreassen, Ole, Igland, Jannicke, Lie, Rolv T, Haavik, Jan, Banasik, Karina, Brunak, Søren, Didriksen, Maria, T. Bruun, Mie, Erikstrup, Christian, Kogelman, Lisette J. A, Nielsen, Kaspar R, Sørensen, Erik, Pedersen, Ole B, Ullum, Henrik, Bay, Jakob, Boldsen, Jens K, Brodersen, Thorsten, Burgdorf, Kristoffer, Dinh, Khoa M, Dowsett, Joseph, Feenstra, Bjarke, Geller, Frank, Hindhede, Lotte, Hjalgrim, Henrik, Jacobsen, Rikke L, Jemec, Gregor, Kaspersen, Katrine, Kjerulf, Bertram D, Larsen, Margit A. H, Louloudis, Ioannis, Lundgaard, Agnete, Mikkelsen, Susan, Mikkelsen, Christina, Nissen, Ioanna, Nyegaard, Mette, Henriksen, Alexander P, Rohde, Palle D, Rostgaard, Klaus, Swinn, Michael, Thørner, Lise W, Bruun, Mie T, Werge, Thomas, Westergaard, David, Masson, Gisli, Thorsteinsdottir, Unnur, Olesen, Jes, Ludvigsson, Petur, Thorarensen, Olafur, Bjornsdottir, Anna, Sigurdardottir, Gudrun R, Sveinsson, Olafur A, Ostrowski, Sisse R, Holm, Hilma, Gudbjartsson, Daniel F, Thorleifsson, Gudmar, Sulem, Patrick, Stefansson, Hreinn, Thorgeirsson, Thorgeir E, Hansen, Thomas F, Stefansson, Kari
Published in Nature genetics

Lessons learned from implementing a national infrastructure in Sweden for storage and analysis of next-generation sequencing data

by Lampa, Samuel, Dahlö, Martin, Olason, Pall I, Hagberg, Jonas, Spjuth, Ola
Published in Gigascience